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Entry version 135 (13 Feb 2019)
Sequence version 2 (21 Feb 2006)
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Protein

TRAF3-interacting JNK-activating modulator

Gene

TRAF3IP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May function as an adapter molecule that regulates TRAF3-mediated JNK activation.By similarity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TRAF3-interacting JNK-activating modulator
Alternative name(s):
TRAF3-interacting protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TRAF3IP3
Synonyms:T3JAM
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000009790.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30766 TRAF3IP3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608255 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9Y228

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 526CytoplasmicSequence analysisAdd BLAST526
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei527 – 544Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST18
Topological domaini545 – 551ExtracellularSequence analysis7

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80342

Open Targets

More...
OpenTargetsi
ENSG00000009790

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670711

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TRAF3IP3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
88984949

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000724031 – 551TRAF3-interacting JNK-activating modulatorAdd BLAST551

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9Y228

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9Y228

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9Y228

PeptideAtlas

More...
PeptideAtlasi
Q9Y228

PRoteomics IDEntifications database

More...
PRIDEi
Q9Y228

ProteomicsDB human proteome resource

More...
ProteomicsDBi
85616
85617 [Q9Y228-2]
85618 [Q9Y228-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9Y228

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9Y228

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9Y228

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000009790 Expressed in 152 organ(s), highest expression level in small intestine Peyer's patch

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9Y228 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9Y228 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA040796

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain.By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123249, 36 interactors

Protein interaction database and analysis system

More...
IntActi
Q9Y228, 71 interactors

Molecular INTeraction database

More...
MINTi
Q9Y228

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000355991

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9Y228

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9Y228

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili240 – 436Sequence analysisAdd BLAST197
Coiled coili464 – 506Sequence analysisAdd BLAST43

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHX6 Eukaryota
ENOG410ZX9A LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160260

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000070108

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG054704

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9Y228

Identification of Orthologs from Complete Genome Data

More...
OMAi
KEPLSCA

Database of Orthologous Groups

More...
OrthoDBi
484467at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9Y228

TreeFam database of animal gene trees

More...
TreeFami
TF334641

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9Y228-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MISPDPRPSP GLARWAESYE AKCERRQEIR ESRRCRPNVT TCRQVGKTLR
60 70 80 90 100
IQQREQLQRA RLQQFFRRRN LELEEKGKAQ HPQAREQGPS RRPGQVTVLK
110 120 130 140 150
EPLSCARRIS SPREQVTGTS SEVFPAQHPP PSGICRDLSD HLSSQAGGLP
160 170 180 190 200
PQDTPIKKPP KHHRGTQTKA EGPTIKNDAS QQTNYGVAVL DKEIIQLSDY
210 220 230 240 250
LKEALQRELV LKQKMVILQD LLSTLIQASD SSWKGQLNED KLKGKLRSLE
260 270 280 290 300
NQLYTCTQKY SPWGMKKVLL EMEDQKNSYE QKAKESLQKV LEEKMNAEQQ
310 320 330 340 350
LQSTQRSLAL AEQKCEEWRS QYEALKEDWR TLGTQHRELE SQLHVLQSKL
360 370 380 390 400
QGADSRDLQM NQALRFLENE HQQLQAKIEC LQGDRDLCSL DTQDLQDQLK
410 420 430 440 450
RSEAEKLTLV TRVQQLQGLL QNQSLQLQEQ EKLLTKKDQA LPVWSPKSFP
460 470 480 490 500
NEVEPEGTGK EKDWDLRDQL QKKTLQLQAK EKECRELHSE LDNLSDEYLS
510 520 530 540 550
CLRKLQHCRE ELNQSQQLPP RRQCGRWLPV LMVVIAAALA VFLANKDNLM

I
Note: No experimental confirmation available.
Length:551
Mass (Da):63,626
Last modified:February 21, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA2DFF45A8D6ED19
GO
Isoform 2 (identifier: Q9Y228-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     95-114: Missing.

Show »
Length:531
Mass (Da):61,375
Checksum:i3ABAB20EEB018E30
GO
Isoform 3 (identifier: Q9Y228-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     352-353: GA → IN
     354-551: Missing.

Note: No experimental confirmation available.
Show »
Length:353
Mass (Da):40,674
Checksum:i5405FE9F07EE18F7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AJU2B1AJU2_HUMAN
TRAF3-interacting JNK-activating mo...
TRAF3IP3
182Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J0C0C9J0C0_HUMAN
TRAF3-interacting JNK-activating mo...
TRAF3IP3
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JBA0C9JBA0_HUMAN
TRAF3-interacting JNK-activating mo...
TRAF3IP3
156Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E2QRE5E2QRE5_HUMAN
TRAF3-interacting JNK-activating mo...
TRAF3IP3
404Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YF09H0YF09_HUMAN
TRAF3-interacting JNK-activating mo...
TRAF3IP3
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JXB3C9JXB3_HUMAN
TRAF3-interacting JNK-activating mo...
TRAF3IP3
26Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024283373Q → E2 PublicationsCorresponds to variant dbSNP:rs669694Ensembl.1
Natural variantiVAR_035664529P → S in a colorectal cancer sample; somatic mutation. 1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01727195 – 114Missing in isoform 2. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_017272352 – 353GA → IN in isoform 3. 1 Publication2
Alternative sequenceiVSP_017273354 – 551Missing in isoform 3. 1 PublicationAdd BLAST198

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL049667 mRNA Translation: CAB41242.1
AL022398 Genomic DNA No translation available.
CH471100 Genomic DNA Translation: EAW93444.1
BC110302 mRNA Translation: AAI10303.1
BC130417 mRNA Translation: AAI30418.1
BC144139 mRNA Translation: AAI44140.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1490.2 [Q9Y228-1]
CCDS81422.1 [Q9Y228-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001274683.1, NM_001287754.1
NP_001307072.1, NM_001320143.1 [Q9Y228-1]
NP_001307073.1, NM_001320144.1 [Q9Y228-2]
NP_079504.2, NM_025228.3 [Q9Y228-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.147434

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367024; ENSP00000355991; ENSG00000009790 [Q9Y228-1]
ENST00000367025; ENSP00000355992; ENSG00000009790 [Q9Y228-1]
ENST00000367026; ENSP00000355993; ENSG00000009790 [Q9Y228-2]
ENST00000478359; ENSP00000417665; ENSG00000009790 [Q9Y228-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80342

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80342

UCSC genome browser

More...
UCSCi
uc001hhm.4 human [Q9Y228-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049667 mRNA Translation: CAB41242.1
AL022398 Genomic DNA No translation available.
CH471100 Genomic DNA Translation: EAW93444.1
BC110302 mRNA Translation: AAI10303.1
BC130417 mRNA Translation: AAI30418.1
BC144139 mRNA Translation: AAI44140.1
CCDSiCCDS1490.2 [Q9Y228-1]
CCDS81422.1 [Q9Y228-2]
RefSeqiNP_001274683.1, NM_001287754.1
NP_001307072.1, NM_001320143.1 [Q9Y228-1]
NP_001307073.1, NM_001320144.1 [Q9Y228-2]
NP_079504.2, NM_025228.3 [Q9Y228-1]
UniGeneiHs.147434

3D structure databases

ProteinModelPortaliQ9Y228
SMRiQ9Y228
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123249, 36 interactors
IntActiQ9Y228, 71 interactors
MINTiQ9Y228
STRINGi9606.ENSP00000355991

PTM databases

iPTMnetiQ9Y228
PhosphoSitePlusiQ9Y228
SwissPalmiQ9Y228

Polymorphism and mutation databases

BioMutaiTRAF3IP3
DMDMi88984949

Proteomic databases

EPDiQ9Y228
jPOSTiQ9Y228
PaxDbiQ9Y228
PeptideAtlasiQ9Y228
PRIDEiQ9Y228
ProteomicsDBi85616
85617 [Q9Y228-2]
85618 [Q9Y228-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
80342
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367024; ENSP00000355991; ENSG00000009790 [Q9Y228-1]
ENST00000367025; ENSP00000355992; ENSG00000009790 [Q9Y228-1]
ENST00000367026; ENSP00000355993; ENSG00000009790 [Q9Y228-2]
ENST00000478359; ENSP00000417665; ENSG00000009790 [Q9Y228-3]
GeneIDi80342
KEGGihsa:80342
UCSCiuc001hhm.4 human [Q9Y228-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80342
DisGeNETi80342
EuPathDBiHostDB:ENSG00000009790.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TRAF3IP3

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0159943
HGNCiHGNC:30766 TRAF3IP3
HPAiHPA040796
MIMi608255 gene
neXtProtiNX_Q9Y228
OpenTargetsiENSG00000009790
PharmGKBiPA142670711

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IHX6 Eukaryota
ENOG410ZX9A LUCA
GeneTreeiENSGT00940000160260
HOGENOMiHOG000070108
HOVERGENiHBG054704
InParanoidiQ9Y228
OMAiKEPLSCA
OrthoDBi484467at2759
PhylomeDBiQ9Y228
TreeFamiTF334641

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TRAF3IP3 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
TRAF3IP3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
80342

Protein Ontology

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PROi
PR:Q9Y228

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000009790 Expressed in 152 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiQ9Y228 baseline and differential
GenevisibleiQ9Y228 HS

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiT3JAM_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9Y228
Secondary accession number(s): A1L464
, A6NIU9, Q2YDB5, Q4VY06, Q7Z706
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: February 21, 2006
Last modified: February 13, 2019
This is version 135 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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