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Protein

Protein jagged-2

Gene

JAG2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity).By similarity

GO - Molecular functioni

  • calcium ion binding Source: InterPro
  • growth factor activity Source: UniProtKB
  • Notch binding Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein
Biological processNotch signaling pathway
LigandCalcium

Enzyme and pathway databases

ReactomeiR-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus
R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants
R-HSA-2660826 Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants
R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus
R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus
SignaLinkiQ9Y219
SIGNORiQ9Y219

Names & Taxonomyi

Protein namesi
Recommended name:
Protein jagged-2
Short name:
Jagged2
Short name:
hJ2
Gene namesi
Name:JAG2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000184916.8
HGNCiHGNC:6189 JAG2
MIMi602570 gene
neXtProtiNX_Q9Y219

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini27 – 1080ExtracellularSequence analysisAdd BLAST1054
Transmembranei1081 – 1101HelicalSequence analysisAdd BLAST21
Topological domaini1102 – 1238CytoplasmicSequence analysisAdd BLAST137

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi3714
OpenTargetsiENSG00000184916
PharmGKBiPA29987

Polymorphism and mutation databases

BioMutaiJAG2
DMDMi116242598

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000000762924 – 1238Protein jagged-2Add BLAST1215

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi153N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi198 ↔ 207By similarity
Disulfide bondi211 ↔ 223By similarity
Disulfide bondi231 ↔ 240By similarity
Disulfide bondi245 ↔ 256By similarity
Disulfide bondi249 ↔ 262By similarity
Disulfide bondi264 ↔ 273By similarity
Disulfide bondi276 ↔ 287By similarity
Disulfide bondi282 ↔ 293By similarity
Disulfide bondi295 ↔ 304By similarity
Disulfide bondi311 ↔ 323By similarity
Disulfide bondi317 ↔ 333By similarity
Disulfide bondi335 ↔ 344By similarity
Disulfide bondi351 ↔ 362By similarity
Disulfide bondi356 ↔ 371By similarity
Disulfide bondi373 ↔ 382By similarity
Disulfide bondi389 ↔ 400By similarity
Disulfide bondi394 ↔ 409By similarity
Disulfide bondi411 ↔ 420By similarity
Disulfide bondi427 ↔ 438By similarity
Disulfide bondi432 ↔ 447By similarity
Disulfide bondi449 ↔ 458By similarity
Disulfide bondi465 ↔ 475By similarity
Disulfide bondi469 ↔ 484By similarity
Disulfide bondi486 ↔ 495By similarity
Disulfide bondi502 ↔ 513By similarity
Disulfide bondi507 ↔ 522By similarity
Disulfide bondi524 ↔ 533By similarity
Disulfide bondi540 ↔ 551By similarity
Disulfide bondi545 ↔ 560By similarity
Disulfide bondi562 ↔ 571By similarity
Glycosylationi570N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi589 ↔ 612Sequence analysis
Disulfide bondi606 ↔ 622Sequence analysis
Glycosylationi619N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi624 ↔ 633By similarity
Disulfide bondi640 ↔ 651By similarity
Disulfide bondi645 ↔ 660By similarity
Disulfide bondi662 ↔ 671By similarity
Disulfide bondi678 ↔ 689By similarity
Disulfide bondi683 ↔ 698By similarity
Disulfide bondi700 ↔ 709By similarity
Disulfide bondi716 ↔ 727By similarity
Disulfide bondi721 ↔ 736By similarity
Disulfide bondi738 ↔ 747By similarity
Glycosylationi752N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi755 ↔ 766By similarity
Disulfide bondi760 ↔ 775By similarity
Disulfide bondi777 ↔ 786By similarity
Disulfide bondi793 ↔ 804By similarity
Disulfide bondi798 ↔ 813By similarity
Disulfide bondi815 ↔ 824By similarity
Disulfide bondi831 ↔ 842By similarity
Disulfide bondi836 ↔ 851By similarity
Disulfide bondi853 ↔ 862By similarity
Glycosylationi1058N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei1123PhosphoserineCombined sources1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

EPDiQ9Y219
PaxDbiQ9Y219
PeptideAtlasiQ9Y219
PRIDEiQ9Y219
ProteomicsDBi85595
85596 [Q9Y219-2]

PTM databases

iPTMnetiQ9Y219
PhosphoSitePlusiQ9Y219

Miscellaneous databases

PMAP-CutDBiQ9Y219

Expressioni

Tissue specificityi

Expressed in heart, placenta and skeletal muscle and to a lesser extent in pancreas. Very low expression in brain, lung, liver and kidney.

Gene expression databases

BgeeiENSG00000184916 Expressed in 222 organ(s), highest expression level in epithelium of mammary gland
CleanExiHS_JAG2
GenevisibleiQ9Y219 HS

Organism-specific databases

HPAiCAB025481
HPA030636
HPA050567

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
GFI1BQ5VTD92EBI-946223,EBI-946212

GO - Molecular functioni

Protein-protein interaction databases

BioGridi109918, 23 interactors
IntActiQ9Y219, 9 interactors
STRINGi9606.ENSP00000328169

Structurei

Secondary structure

11238
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ9Y219
SMRiQ9Y219
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini196 – 240DSLPROSITE-ProRule annotationAdd BLAST45
Domaini241 – 274EGF-like 1PROSITE-ProRule annotationAdd BLAST34
Domaini275 – 305EGF-like 2; atypicalPROSITE-ProRule annotationAdd BLAST31
Domaini307 – 345EGF-like 3PROSITE-ProRule annotationAdd BLAST39
Domaini347 – 383EGF-like 4PROSITE-ProRule annotationAdd BLAST37
Domaini385 – 421EGF-like 5; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini423 – 459EGF-like 6; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini461 – 496EGF-like 7; calcium-bindingPROSITE-ProRule annotationAdd BLAST36
Domaini498 – 534EGF-like 8PROSITE-ProRule annotationAdd BLAST37
Domaini536 – 572EGF-like 9PROSITE-ProRule annotationAdd BLAST37
Domaini574 – 634EGF-like 10; atypicalPROSITE-ProRule annotationAdd BLAST61
Domaini636 – 672EGF-like 11; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini674 – 710EGF-like 12; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini712 – 748EGF-like 13PROSITE-ProRule annotationAdd BLAST37
Domaini751 – 787EGF-like 14PROSITE-ProRule annotationAdd BLAST37
Domaini789 – 825EGF-like 15; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini827 – 863EGF-like 16; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini870 – 944VWFCPROSITE-ProRule annotationAdd BLAST75

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1217 Eukaryota
ENOG410XP6K LUCA
GeneTreeiENSGT00810000125346
HOGENOMiHOG000113124
HOVERGENiHBG031645
InParanoidiQ9Y219
KOiK21635
OMAiGVNCHIN
OrthoDBiEOG091G0A88
PhylomeDBiQ9Y219
TreeFamiTF351835

Family and domain databases

InterProiView protein in InterPro
IPR001774 DSL
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR009030 Growth_fac_rcpt_cys_sf
IPR033108 Jag2
IPR026219 Jagged/Serrate
IPR011651 Notch_ligand_N
IPR001007 VWF_dom
PANTHERiPTHR44097:SF1 PTHR44097:SF1, 1 hit
PfamiView protein in Pfam
PF01414 DSL, 1 hit
PF00008 EGF, 10 hits
PF07645 EGF_CA, 1 hit
PF12661 hEGF, 2 hits
PF07657 MNNL, 1 hit
PRINTSiPR02059 JAGGEDFAMILY
SMARTiView protein in SMART
SM00051 DSL, 1 hit
SM00181 EGF, 16 hits
SM00179 EGF_CA, 14 hits
SM00214 VWC, 1 hit
SM00215 VWC_out, 1 hit
SUPFAMiSSF57184 SSF57184, 2 hits
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 10 hits
PS51051 DSL, 1 hit
PS00022 EGF_1, 16 hits
PS01186 EGF_2, 12 hits
PS50026 EGF_3, 15 hits
PS01187 EGF_CA, 8 hits
PS50184 VWFC_2, 1 hit

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform Long (identifier: Q9Y219-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRAQGRGRLP RRLLLLLALW VQAARPMGYF ELQLSALRNV NGELLSGACC
60 70 80 90 100
DGDGRTTRAG GCGHDECDTY VRVCLKEYQA KVTPTGPCSY GHGATPVLGG
110 120 130 140 150
NSFYLPPAGA AGDRARARAR AGGDQDPGLV VIPFQFAWPR SFTLIVEAWD
160 170 180 190 200
WDNDTTPNEE LLIERVSHAG MINPEDRWKS LHFSGHVAHL ELQIRVRCDE
210 220 230 240 250
NYYSATCNKF CRPRNDFFGH YTCDQYGNKA CMDGWMGKEC KEAVCKQGCN
260 270 280 290 300
LLHGGCTVPG ECRCSYGWQG RFCDECVPYP GCVHGSCVEP WQCNCETNWG
310 320 330 340 350
GLLCDKDLNY CGSHHPCTNG GTCINAEPDQ YRCTCPDGYS GRNCEKAEHA
360 370 380 390 400
CTSNPCANGG SCHEVPSGFE CHCPSGWSGP TCALDIDECA SNPCAAGGTC
410 420 430 440 450
VDQVDGFECI CPEQWVGATC QLDANECEGK PCLNAFSCKN LIGGYYCDCI
460 470 480 490 500
PGWKGINCHI NVNDCRGQCQ HGGTCKDLVN GYQCVCPRGF GGRHCELERD
510 520 530 540 550
ECASSPCHSG GLCEDLADGF HCHCPQGFSG PLCEVDVDLC EPSPCRNGAR
560 570 580 590 600
CYNLEGDYYC ACPDDFGGKN CSVPREPCPG GACRVIDGCG SDAGPGMPGT
610 620 630 640 650
AASGVCGPHG RCVSQPGGNF SCICDSGFTG TYCHENIDDC LGQPCRNGGT
660 670 680 690 700
CIDEVDAFRC FCPSGWEGEL CDTNPNDCLP DPCHSRGRCY DLVNDFYCAC
710 720 730 740 750
DDGWKGKTCH SREFQCDAYT CSNGGTCYDS GDTFRCACPP GWKGSTCAVA
760 770 780 790 800
KNSSCLPNPC VNGGTCVGSG ASFSCICRDG WEGRTCTHNT NDCNPLPCYN
810 820 830 840 850
GGICVDGVNW FRCECAPGFA GPDCRINIDE CQSSPCAYGA TCVDEINGYR
860 870 880 890 900
CSCPPGRAGP RCQEVIGFGR SCWSRGTPFP HGSSWVEDCN SCRCLDGRRD
910 920 930 940 950
CSKVWCGWKP CLLAGQPEAL SAQCPLGQRC LEKAPGQCLR PPCEAWGECG
960 970 980 990 1000
AEEPPSTPCL PRSGHLDNNC ARLTLHFNRD HVPQGTTVGA ICSGIRSLPA
1010 1020 1030 1040 1050
TRAVARDRLL VLLCDRASSG ASAVEVAVSF SPARDLPDSS LIQGAAHAIV
1060 1070 1080 1090 1100
AAITQRGNSS LLLAVTEVKV ETVVTGGSST GLLVPVLCGA FSVLWLACVV
1110 1120 1130 1140 1150
LCVWWTRKRR KERERSRLPR EESANNQWAP LNPIRNPIER PGGHKDVLYQ
1160 1170 1180 1190 1200
CKNFTPPPRR ADEALPGPAG HAAVREDEED EDLGRGEEDS LEAEKFLSHK
1210 1220 1230
FTKDPGRSPG RPAHWASGPK VDNRAVRSIN EARYAGKE
Length:1,238
Mass (Da):133,367
Last modified:October 17, 2006 - v3
Checksum:i23B4FCD7D2891EF7
GO
Isoform Short (identifier: Q9Y219-2) [UniParc]FASTAAdd to basket
Also known as: HJAG2.del-E6

The sequence of this isoform differs from the canonical sequence as follows:
     424-461: Missing.

Show »
Length:1,200
Mass (Da):129,235
Checksum:iC74AA0EE201D5FA7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti8 – 12RLPRR → AFPPA in AAB71189 (PubMed:9315665).Curated5
Sequence conflicti119A → P in AAB71189 (PubMed:9315665).Curated1
Sequence conflicti129L → F in AAB71189 (PubMed:9315665).Curated1
Sequence conflicti384L → SA in CAA74706 (PubMed:9486542).Curated1
Sequence conflicti424 – 426ANE → VND in AAB71189 (PubMed:9315665).Curated3
Sequence conflicti1235A → V in AAB61285 (PubMed:10079256).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_028113501E → K3 PublicationsCorresponds to variant dbSNP:rs1057744Ensembl.1
Natural variantiVAR_048986538D → N. Corresponds to variant dbSNP:rs9972231Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_001395424 – 461Missing in isoform Short. 1 PublicationAdd BLAST38

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020201 mRNA Translation: AAB71189.1
AF003521 mRNA Translation: AAB61285.1
AF029778 mRNA Translation: AAB84215.1
AF029779 mRNA Translation: AAB84216.1
AF111170 Genomic DNA Translation: AAD15562.1
Y14330 mRNA Translation: CAA74706.1
CCDSiCCDS9998.1 [Q9Y219-1]
CCDS9999.1 [Q9Y219-2]
RefSeqiNP_002217.3, NM_002226.4 [Q9Y219-1]
NP_660142.1, NM_145159.2 [Q9Y219-2]
UniGeneiHs.433445

Genome annotation databases

EnsembliENST00000331782; ENSP00000328169; ENSG00000184916 [Q9Y219-1]
ENST00000347004; ENSP00000328566; ENSG00000184916 [Q9Y219-2]
GeneIDi3714
KEGGihsa:3714
UCSCiuc001yqg.4 human [Q9Y219-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Cross-referencesi

Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020201 mRNA Translation: AAB71189.1
AF003521 mRNA Translation: AAB61285.1
AF029778 mRNA Translation: AAB84215.1
AF029779 mRNA Translation: AAB84216.1
AF111170 Genomic DNA Translation: AAD15562.1
Y14330 mRNA Translation: CAA74706.1
CCDSiCCDS9998.1 [Q9Y219-1]
CCDS9999.1 [Q9Y219-2]
RefSeqiNP_002217.3, NM_002226.4 [Q9Y219-1]
NP_660142.1, NM_145159.2 [Q9Y219-2]
UniGeneiHs.433445

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5MW5X-ray2.70A27-309[»]
5MW7X-ray2.80A27-348[»]
5MWFX-ray2.80A/B/C/D/E/F27-309[»]
ProteinModelPortaliQ9Y219
SMRiQ9Y219
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi109918, 23 interactors
IntActiQ9Y219, 9 interactors
STRINGi9606.ENSP00000328169

PTM databases

iPTMnetiQ9Y219
PhosphoSitePlusiQ9Y219

Polymorphism and mutation databases

BioMutaiJAG2
DMDMi116242598

Proteomic databases

EPDiQ9Y219
PaxDbiQ9Y219
PeptideAtlasiQ9Y219
PRIDEiQ9Y219
ProteomicsDBi85595
85596 [Q9Y219-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000331782; ENSP00000328169; ENSG00000184916 [Q9Y219-1]
ENST00000347004; ENSP00000328566; ENSG00000184916 [Q9Y219-2]
GeneIDi3714
KEGGihsa:3714
UCSCiuc001yqg.4 human [Q9Y219-1]

Organism-specific databases

CTDi3714
DisGeNETi3714
EuPathDBiHostDB:ENSG00000184916.8
GeneCardsiJAG2
H-InvDBiHIX0037647
HGNCiHGNC:6189 JAG2
HPAiCAB025481
HPA030636
HPA050567
MIMi602570 gene
neXtProtiNX_Q9Y219
OpenTargetsiENSG00000184916
PharmGKBiPA29987
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1217 Eukaryota
ENOG410XP6K LUCA
GeneTreeiENSGT00810000125346
HOGENOMiHOG000113124
HOVERGENiHBG031645
InParanoidiQ9Y219
KOiK21635
OMAiGVNCHIN
OrthoDBiEOG091G0A88
PhylomeDBiQ9Y219
TreeFamiTF351835

Enzyme and pathway databases

ReactomeiR-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus
R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants
R-HSA-2660826 Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants
R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus
R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus
SignaLinkiQ9Y219
SIGNORiQ9Y219

Miscellaneous databases

ChiTaRSiJAG2 human
GeneWikiiJAG2
GenomeRNAii3714
PMAP-CutDBiQ9Y219
PROiPR:Q9Y219
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000184916 Expressed in 222 organ(s), highest expression level in epithelium of mammary gland
CleanExiHS_JAG2
GenevisibleiQ9Y219 HS

Family and domain databases

InterProiView protein in InterPro
IPR001774 DSL
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR009030 Growth_fac_rcpt_cys_sf
IPR033108 Jag2
IPR026219 Jagged/Serrate
IPR011651 Notch_ligand_N
IPR001007 VWF_dom
PANTHERiPTHR44097:SF1 PTHR44097:SF1, 1 hit
PfamiView protein in Pfam
PF01414 DSL, 1 hit
PF00008 EGF, 10 hits
PF07645 EGF_CA, 1 hit
PF12661 hEGF, 2 hits
PF07657 MNNL, 1 hit
PRINTSiPR02059 JAGGEDFAMILY
SMARTiView protein in SMART
SM00051 DSL, 1 hit
SM00181 EGF, 16 hits
SM00179 EGF_CA, 14 hits
SM00214 VWC, 1 hit
SM00215 VWC_out, 1 hit
SUPFAMiSSF57184 SSF57184, 2 hits
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 10 hits
PS51051 DSL, 1 hit
PS00022 EGF_1, 16 hits
PS01186 EGF_2, 12 hits
PS50026 EGF_3, 15 hits
PS01187 EGF_CA, 8 hits
PS50184 VWFC_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJAG2_HUMAN
AccessioniPrimary (citable) accession number: Q9Y219
Secondary accession number(s): Q9UE17
, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: October 17, 2006
Last modified: November 7, 2018
This is version 186 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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