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Protein

Alpha-amylase

Gene

group 4 allergen

Organism
Euroglyphus maynei (Mayne's house dust mite)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase
Biological processCarbohydrate metabolismUniRule annotationSAAS annotation

Protein family/group databases

CAZyiGH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotationSAAS annotation (EC:3.2.1.1UniRule annotationSAAS annotation)
Gene namesi
Name:group 4 allergenImported
OrganismiEuroglyphus maynei (Mayne's house dust mite)Imported
Taxonomic identifieri6958 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaePyroglyphinaeEuroglyphus

Pathology & Biotechi

Protein family/group databases

Allergomei3277 Eur m 4.0101
344 Eur m 4

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500433784326 – 521Alpha-amylaseSequence analysisAdd BLAST496

Structurei

3D structure databases

ProteinModelPortaliQ9Y196
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 419AamyInterPro annotationAdd BLAST383
Domaini428 – 519Aamy_CInterPro annotationAdd BLAST92

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.40.1180, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR031319 A-amylase_C
IPR006046 Alpha_amylase
IPR006047 Glyco_hydro_13_cat_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PRINTSiPR00110 ALPHAAMYLASE
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SM00632 Aamy_C, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Y196-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPKIYLKLI TVLFISLFVQ NNVHCKYHNP HFIGNRCVIT HLMEWKYDDI
60 70 80 90 100
GDECERFLGP YGYGGVQVSP VNEHAILDRR PWYERYQPVS YDLRTRSGDE
110 120 130 140 150
QQFRRMVKRC NKAGVRIYVD IVLNHMTGGQ SGQGTNGNHY NGITMQYPGV
160 170 180 190 200
PFGPNDFHGH ESCQTKDLEI HNYSDRNEAR NCRLSGLRDL KQQSEYVRKK
210 220 230 240 250
QVDFLNHLID IGVAGFRSDA STHQWPDDLR SIYSQLHTLN KEFFPENSHP
260 270 280 290 300
FIYHETIYYG GNGINSNEYT SLGRIIEFRF YKEITNVFRG NNQLRWLKNF
310 320 330 340 350
GTEWGLVPSN DALVMIDSHD LRVGHTGKLG FNINCFEARL LKASTAFMLA
360 370 380 390 400
WNYGIPRVMS SYFWNQIIRD GKDVNDWVGP PTDQHGNILS VHPNADLTCN
410 420 430 440 450
HEWICEHRWR QIYNMVRFKM IAGQEPVRNW WDNGDYQIAF SRGSHAFIAI
460 470 480 490 500
NLQKNGDKNL RQRLHTGLPA GTYCDIISGD LIHNKCTGKS IQVDKNGLAD
510 520
IYVGHDELDA FVAYHIGARI E
Length:521
Mass (Da):60,271
Last modified:November 1, 1999 - v1
Checksum:iC6DA122F49868737
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF144061 mRNA Translation: AAD38943.1

Similar proteinsi

Entry informationi

Entry nameiQ9Y196_EURMA
AccessioniPrimary (citable) accession number: Q9Y196
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: July 18, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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