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Entry version 134 (08 May 2019)
Sequence version 1 (01 Nov 1999)
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Protein

Phosphatidylinositol-binding clathrin assembly protein unc-11

Gene

unc-11

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Required for the efficient targeting of the synaptic vesicle protein synaptobrevin.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processEndocytosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-432722 Golgi Associated Vesicle Biogenesis
R-CEL-8856825 Cargo recognition for clathrin-mediated endocytosis
R-CEL-8856828 Clathrin-mediated endocytosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphatidylinositol-binding clathrin assembly protein unc-11
Alternative name(s):
AP180-like adaptor protein
Uncoordinated protein 11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:unc-11
ORF Names:C32E8.10
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

WormBase

More...
WormBasei
C32E8.10a ; CE23562 ; WBGene00006751 ; unc-11
C32E8.10b ; CE27812 ; WBGene00006751 ; unc-11
C32E8.10c ; CE24822 ; WBGene00006751 ; unc-11
C32E8.10d ; CE23564 ; WBGene00006751 ; unc-11
C32E8.10e ; CE23565 ; WBGene00006751 ; unc-11
C32E8.10f ; CE23566 ; WBGene00006751 ; unc-11
C32E8.10h ; CE27813 ; WBGene00006751 ; unc-11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Coated pit, Cytoplasmic vesicle, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001870651 – 586Phosphatidylinositol-binding clathrin assembly protein unc-11Add BLAST586

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9XZI6

PeptideAtlas

More...
PeptideAtlasi
Q9XZI6

PRoteomics IDEntifications database

More...
PRIDEi
Q9XZI6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9XZI6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

High levels in the nervous system and at lower levels in other tissues. In neurons, enriched at presynaptic terminals and is also present in cell bodies.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00006751 Expressed in 5 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds clathrin and phosphatidylinositol 4,5-bisphosphate.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
37426, 3 interactors

Database of interacting proteins

More...
DIPi
DIP-25315N

Protein interaction database and analysis system

More...
IntActi
Q9XZI6, 8 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9XZI6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini29 – 161ENTHPROSITE-ProRule annotationCuratedAdd BLAST133

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PICALM/SNAP91 family.Curated

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183068

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9XZI6

KEGG Orthology (KO)

More...
KOi
K20044

Identification of Orthologs from Complete Genome Data

More...
OMAi
TNPFARR

Database of Orthologous Groups

More...
OrthoDBi
755817at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9XZI6

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.58.150, 1 hit
1.25.40.90, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011417 ANTH_dom
IPR014712 Clathrin_AP_dom2
IPR013809 ENTH
IPR008942 ENTH_VHS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07651 ANTH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00273 ENTH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48464 SSF48464, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50942 ENTH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (9)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 9 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform A1 Publication (identifier: Q9XZI6-1) [UniParc]FASTAAdd to basket
Also known as: aCurated

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQTIEKALHQ PMPFTTGGQT ISDRLTAAKH SLAGSQLGKT ICKATTEEVM
60 70 80 90 100
APKKKHLDYL LHCTNEPNVS IPSMANLLIE RTQNPNWTVV YKALITIHNI
110 120 130 140 150
MCYGNERFSQ YLASCNTTFN LTAFVDKVGG AGGYDMSTHV RRYAKYIGEK
160 170 180 190 200
INTYRMCAFD FCKVKRGRED GLLRTMHTDK LLKTIPILQN QIDALLEFSV
210 220 230 240 250
TTSELNNGVI NCSFILLFRD LIRLFACYND GIINVLEKYF DMNKKQCRDA
260 270 280 290 300
LDTYKSFLTR LDKVAEFLRV AESVGIDRGE IPDLTRAPAS LLEALEAHLI
310 320 330 340 350
HLEGGKAPPP TQQHVAPHQF TTGFAFSQQP QPALGDAERQ RYIELEQERL
360 370 380 390 400
RQFEDQKKSI NSANPFANDV ASAAPAPATS AAQPDLLDMF QSSAAPAPQT
410 420 430 440 450
ADVTNPFGNF AAPSAFPTNV PPPAAHSAPF GVQPAPQHSA APFYANLHQA
460 470 480 490 500
PPMQSQAPNG HQAAPFGYPN AHPDDLARMT AQMSLNQQGA PAGWNTTTSA
510 520 530 540 550
VSNNPFGATS APQPMYTAPM GMYQQPFGAQ PMWNPAMAAY GQQYGYGQPV
560 570 580
PPQQQHQIQL VHAAMAAKNA AQAQQAQAAS ADPFGL
Length:586
Mass (Da):64,064
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E337A81D302DD81
GO
Isoform B1 Publication (identifier: Q9XZI6-2) [UniParc]FASTAAdd to basket
Also known as: hCurated

The sequence of this isoform differs from the canonical sequence as follows:
     419-458: Missing.
     489-489: G → GYR

Show »
Length:548
Mass (Da):60,273
Checksum:i8641691EF297D717
GO
Isoform C1 Publication (identifier: Q9XZI6-3) [UniParc]FASTAAdd to basket
Also known as: bCurated

The sequence of this isoform differs from the canonical sequence as follows:
     419-458: Missing.

Show »
Length:546
Mass (Da):59,954
Checksum:i69D424C56BAF517A
GO
Isoform c (identifier: Q9XZI6-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     459-459: N → NEPENPFITAPAAPQMHNAPPVPPPPASQGAPAPINPFADPSATAASSAQPFGDPDDFKFEQKNVKIKILIP

Note: No experimental confirmation available.
Show »
Length:657
Mass (Da):71,443
Checksum:i891BA9FB3525AAD2
GO
Isoform D1 Publication (identifier: Q9XZI6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     397-449: Missing.
     489-489: G → GYR

Show »
Length:535
Mass (Da):58,978
Checksum:i7EB8FC25A2896AA5
GO
Isoform d (identifier: Q9XZI6-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     397-408: APQTADVTNPFG → LLQCNRKLQMVS
     409-460: Missing.

Note: No experimental confirmation available.
Show »
Length:534
Mass (Da):58,994
Checksum:i4FDEE1FAEDBA4847
GO
Isoform E1 Publication (identifier: Q9XZI6-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     383-512: Missing.

Show »
Length:456
Mass (Da):50,727
Checksum:i44EDE64136212A9E
GO
Isoform e (identifier: Q9XZI6-9) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     383-467: QPDLLDMFQS...PNGHQAAPFG → HQCIRLQWEC...LVVYFSLSLS
     468-586: Missing.

Note: No experimental confirmation available.
Show »
Length:467
Mass (Da):53,131
Checksum:i42042675FC806DA9
GO
Isoform fCurated (identifier: Q9XZI6-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-388: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:198
Mass (Da):20,632
Checksum:i2F38F15C93F0F0C1
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0506791 – 388Missing in isoform f. CuratedAdd BLAST388
Alternative sequenceiVSP_050680383 – 512Missing in isoform E. 1 PublicationAdd BLAST130
Alternative sequenceiVSP_020098383 – 467QPDLL…AAPFG → HQCIRLQWECINNHLVLSQC GILRWQHTVNNMDTDNLFHH NSNTKFNWFMQRWLQRTLHK LNRPRPPQPIHLDYSLVVYF SLSLS in isoform e. 1 PublicationAdd BLAST85
Alternative sequenceiVSP_050681397 – 449Missing in isoform D. 1 PublicationAdd BLAST53
Alternative sequenceiVSP_020099397 – 408APQTA…TNPFG → LLQCNRKLQMVS in isoform d. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_020100409 – 460Missing in isoform d. 1 PublicationAdd BLAST52
Alternative sequenceiVSP_050682419 – 458Missing in isoform C and isoform B. 1 PublicationAdd BLAST40
Alternative sequenceiVSP_020101459N → NEPENPFITAPAAPQMHNAP PVPPPPASQGAPAPINPFAD PSATAASSAQPFGDPDDFKF EQKNVKIKILIP in isoform c. 1 Publication1
Alternative sequenceiVSP_020102468 – 586Missing in isoform e. 1 PublicationAdd BLAST119
Alternative sequenceiVSP_050683489G → GYR in isoform B and isoform D. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF144257 mRNA Translation: AAD37365.1
AF144258 mRNA Translation: AAD37366.1
AF144259 mRNA Translation: AAD37367.1
AF144260 mRNA Translation: AAD37368.1
AF144261 mRNA Translation: AAD37369.1
AF144262 mRNA Translation: AAD37370.1
FO080749 Genomic DNA Translation: CCD66409.1
FO080749 Genomic DNA Translation: CCD66410.1
FO080749 Genomic DNA Translation: CCD66411.1
FO080749 Genomic DNA Translation: CCD66412.1
FO080749 Genomic DNA Translation: CCD66413.1
FO080749 Genomic DNA Translation: CCD66414.1
FO080749 Genomic DNA Translation: CCD66415.1

NCBI Reference Sequences

More...
RefSeqi
NP_001021014.1, NM_001025843.2 [Q9XZI6-3]
NP_001021015.1, NM_001025844.1 [Q9XZI6-9]
NP_001021016.1, NM_001025845.2 [Q9XZI6-2]
NP_491227.1, NM_058826.1 [Q9XZI6-1]
NP_491228.1, NM_058827.3 [Q9XZI6-7]
NP_491229.1, NM_058828.1 [Q9XZI6-8]
NP_491230.1, NM_058829.3 [Q9XZI6-6]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C32E8.10a; C32E8.10a; WBGene00006751 [Q9XZI6-1]
C32E8.10b; C32E8.10b; WBGene00006751 [Q9XZI6-3]
C32E8.10c; C32E8.10c; WBGene00006751 [Q9XZI6-7]
C32E8.10d; C32E8.10d; WBGene00006751 [Q9XZI6-8]
C32E8.10e; C32E8.10e; WBGene00006751 [Q9XZI6-9]
C32E8.10f; C32E8.10f; WBGene00006751 [Q9XZI6-6]
C32E8.10h; C32E8.10h; WBGene00006751 [Q9XZI6-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
171952

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C32E8.10

UCSC genome browser

More...
UCSCi
C32E8.10f c. elegans [Q9XZI6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF144257 mRNA Translation: AAD37365.1
AF144258 mRNA Translation: AAD37366.1
AF144259 mRNA Translation: AAD37367.1
AF144260 mRNA Translation: AAD37368.1
AF144261 mRNA Translation: AAD37369.1
AF144262 mRNA Translation: AAD37370.1
FO080749 Genomic DNA Translation: CCD66409.1
FO080749 Genomic DNA Translation: CCD66410.1
FO080749 Genomic DNA Translation: CCD66411.1
FO080749 Genomic DNA Translation: CCD66412.1
FO080749 Genomic DNA Translation: CCD66413.1
FO080749 Genomic DNA Translation: CCD66414.1
FO080749 Genomic DNA Translation: CCD66415.1
RefSeqiNP_001021014.1, NM_001025843.2 [Q9XZI6-3]
NP_001021015.1, NM_001025844.1 [Q9XZI6-9]
NP_001021016.1, NM_001025845.2 [Q9XZI6-2]
NP_491227.1, NM_058826.1 [Q9XZI6-1]
NP_491228.1, NM_058827.3 [Q9XZI6-7]
NP_491229.1, NM_058828.1 [Q9XZI6-8]
NP_491230.1, NM_058829.3 [Q9XZI6-6]

3D structure databases

SMRiQ9XZI6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi37426, 3 interactors
DIPiDIP-25315N
IntActiQ9XZI6, 8 interactors

PTM databases

iPTMnetiQ9XZI6

Proteomic databases

EPDiQ9XZI6
PeptideAtlasiQ9XZI6
PRIDEiQ9XZI6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC32E8.10a; C32E8.10a; WBGene00006751 [Q9XZI6-1]
C32E8.10b; C32E8.10b; WBGene00006751 [Q9XZI6-3]
C32E8.10c; C32E8.10c; WBGene00006751 [Q9XZI6-7]
C32E8.10d; C32E8.10d; WBGene00006751 [Q9XZI6-8]
C32E8.10e; C32E8.10e; WBGene00006751 [Q9XZI6-9]
C32E8.10f; C32E8.10f; WBGene00006751 [Q9XZI6-6]
C32E8.10h; C32E8.10h; WBGene00006751 [Q9XZI6-2]
GeneIDi171952
KEGGicel:CELE_C32E8.10
UCSCiC32E8.10f c. elegans [Q9XZI6-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
171952
WormBaseiC32E8.10a ; CE23562 ; WBGene00006751 ; unc-11
C32E8.10b ; CE27812 ; WBGene00006751 ; unc-11
C32E8.10c ; CE24822 ; WBGene00006751 ; unc-11
C32E8.10d ; CE23564 ; WBGene00006751 ; unc-11
C32E8.10e ; CE23565 ; WBGene00006751 ; unc-11
C32E8.10f ; CE23566 ; WBGene00006751 ; unc-11
C32E8.10h ; CE27813 ; WBGene00006751 ; unc-11

Phylogenomic databases

GeneTreeiENSGT00950000183068
InParanoidiQ9XZI6
KOiK20044
OMAiTNPFARR
OrthoDBi755817at2759
PhylomeDBiQ9XZI6

Enzyme and pathway databases

ReactomeiR-CEL-432722 Golgi Associated Vesicle Biogenesis
R-CEL-8856825 Cargo recognition for clathrin-mediated endocytosis
R-CEL-8856828 Clathrin-mediated endocytosis

Miscellaneous databases

Protein Ontology

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PROi
PR:Q9XZI6

Gene expression databases

BgeeiWBGene00006751 Expressed in 5 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

Family and domain databases

Gene3Di1.20.58.150, 1 hit
1.25.40.90, 1 hit
InterProiView protein in InterPro
IPR011417 ANTH_dom
IPR014712 Clathrin_AP_dom2
IPR013809 ENTH
IPR008942 ENTH_VHS
PfamiView protein in Pfam
PF07651 ANTH, 1 hit
SMARTiView protein in SMART
SM00273 ENTH, 1 hit
SUPFAMiSSF48464 SSF48464, 1 hit
PROSITEiView protein in PROSITE
PS50942 ENTH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPICAL_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9XZI6
Secondary accession number(s): Q95Q72
, Q95Q73, Q95Q74, Q95Q75, Q9UA04, Q9UA05, Q9XZI7, Q9XZI8, Q9XZI9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: November 1, 1999
Last modified: May 8, 2019
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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