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Protein

Putative H/ACA ribonucleoprotein complex subunit 2-like protein

Gene

Y48A6B.3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, RNA-binding
Biological processRibosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Putative H/ACA ribonucleoprotein complex subunit 2-like protein
Gene namesi
ORF Names:Y48A6B.3
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiY48A6B.3 ; CE19186 ; WBGene00012964

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001367711 – 163Putative H/ACA ribonucleoprotein complex subunit 2-like proteinAdd BLAST163

Proteomic databases

EPDiQ9XXD4
PaxDbiQ9XXD4
PeptideAtlasiQ9XXD4
PRIDEiQ9XXD4

Expressioni

Gene expression databases

BgeeiWBGene00012964

Interactioni

Subunit structurei

Component of the small nucleolar ribonucleoprotein particle containing H/ACA-type snoRNAs (H/ACA snoRNPs).

Protein-protein interaction databases

STRINGi6239.Y48A6B.3.1

Structurei

3D structure databases

ProteinModelPortaliQ9XXD4
SMRiQ9XXD4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3167 Eukaryota
COG1358 LUCA
GeneTreeiENSGT00550000074939
HOGENOMiHOG000055227
InParanoidiQ9XXD4
KOiK11129
OMAiNIPYCYT
OrthoDBiEOG091G0VZK
PhylomeDBiQ9XXD4

Family and domain databases

Gene3Di3.30.1330.30, 1 hit
InterProiView protein in InterPro
IPR002415 H/ACA_rnp_Nhp2_euk
IPR029064 L30e-like
IPR004038 Ribosomal_L7Ae/L30e/S12e/Gad45
IPR018492 Ribosomal_L7Ae/L8/Nhp2
IPR004037 Ribosomal_L7Ae_CS
PfamiView protein in Pfam
PF01248 Ribosomal_L7Ae, 1 hit
PRINTSiPR00881 L7ARS6FAMILY
PR00883 NUCLEARHMG
SUPFAMiSSF55315 SSF55315, 1 hit
PROSITEiView protein in PROSITE
PS01082 RIBOSOMAL_L7AE, 1 hit

Sequencei

Sequence statusi: Complete.

Q9XXD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKRNLDETM NESTVSEANG DATAPTTEKD EYQALCELVN PIAQPLANRK
60 70 80 90 100
LAKKVYKLIK KASAGDKTLR EGIKDVQKEL RRNEKGICIL AGNVSPIDVY
110 120 130 140 150
SHIPGICEEK EIPYVYIPSR EQLGLAVGHR RPSILIFVKP SGDFKELYDE
160
VAEALRHLTV EAA
Length:163
Mass (Da):18,091
Last modified:November 1, 1999 - v1
Checksum:iD1440685F584651A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL023844 Genomic DNA Translation: CAA19527.1
PIRiT26980
RefSeqiNP_499415.1, NM_067014.5
UniGeneiCel.9762

Genome annotation databases

EnsemblMetazoaiY48A6B.3; Y48A6B.3; WBGene00012964
GeneIDi176531
KEGGicel:CELE_Y48A6B.3
UCSCiY48A6B.3.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiNHP2_CAEEL
AccessioniPrimary (citable) accession number: Q9XXD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: November 1, 1999
Last modified: June 20, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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