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Protein

40S ribosomal protein S15

Gene

rps-15

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Negatively regulates lifespan.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • RNA binding Source: InterPro
  • structural constituent of ribosome Source: GO_Central

GO - Biological processi

  • determination of adult lifespan Source: WormBase
  • ribosomal small subunit assembly Source: GO_Central
  • translation Source: InterPro

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-CEL-72649 Translation initiation complex formation
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-CEL-72702 Ribosomal scanning and start codon recognition
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S15
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rps-15Imported
ORF Names:F36A2.6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

WormBase

More...
WormBasei
F36A2.6 ; CE09945 ; WBGene00004484 ; rps-15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001300372 – 15140S ribosomal protein S15Add BLAST150

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanine1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9XVP0

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9XVP0

PeptideAtlas

More...
PeptideAtlasi
Q9XVP0

PRoteomics IDEntifications database

More...
PRIDEi
Q9XVP0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9XVP0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00004484 Expressed in 5 organ(s), highest expression level in material anatomical entity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
38126, 10 interactors

Protein interaction database and analysis system

More...
IntActi
Q9XVP0, 12 interactors

STRING: functional protein association networks

More...
STRINGi
6239.F36A2.6.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9XVP0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9XVP0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS19 family.Sequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0898 Eukaryota
COG0185 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000475

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111561

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9XVP0

KEGG Orthology (KO)

More...
KOi
K02958

Identification of Orthologs from Complete Genome Data

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OMAi
VIRTHCR

Database of Orthologous Groups

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OrthoDBi
EOG091G0ZRG

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9XVP0

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.30.860.20, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00531 Ribosomal_S19, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002222 Ribosomal_S19
IPR020934 Ribosomal_S19_CS
IPR023575 Ribosomal_S19_SF
IPR005713 Ribosomal_S19A/S15e

The PANTHER Classification System

More...
PANTHERi
PTHR11880 PTHR11880, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00203 Ribosomal_S19, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002144 Ribosomal_S19, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00975 RIBOSOMALS19

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54570 SSF54570, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01025 uS19_arch, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00323 RIBOSOMAL_S19, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9XVP0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATQDDAHLA ELKKKRTFRK FMYRGVDLDQ LLDMSREQFT KLLPCRMRRR
60 70 80 90 100
LDRGLKRKHL ALIAKVQKAK KAAGVLEKPA TVKTHLRDMI ILPELVGGVI
110 120 130 140 150
GIYNGKVFNQ TEIKPEMIGF YLGEFAISYK PVKHGRPGIG ATHSSRFIPL

K
Length:151
Mass (Da):17,244
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i146D97D8669C100C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z81077 Genomic DNA Translation: CAB03065.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T21828

NCBI Reference Sequences

More...
RefSeqi
NP_492384.1, NM_059983.5

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Cel.8614

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F36A2.6; F36A2.6; WBGene00004484

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
172693

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F36A2.6

UCSC genome browser

More...
UCSCi
F36A2.6.2 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z81077 Genomic DNA Translation: CAB03065.1
PIRiT21828
RefSeqiNP_492384.1, NM_059983.5
UniGeneiCel.8614

3D structure databases

ProteinModelPortaliQ9XVP0
SMRiQ9XVP0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi38126, 10 interactors
IntActiQ9XVP0, 12 interactors
STRINGi6239.F36A2.6.1

PTM databases

iPTMnetiQ9XVP0

Proteomic databases

EPDiQ9XVP0
PaxDbiQ9XVP0
PeptideAtlasiQ9XVP0
PRIDEiQ9XVP0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF36A2.6; F36A2.6; WBGene00004484
GeneIDi172693
KEGGicel:CELE_F36A2.6
UCSCiF36A2.6.2 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
172693
WormBaseiF36A2.6 ; CE09945 ; WBGene00004484 ; rps-15

Phylogenomic databases

eggNOGiKOG0898 Eukaryota
COG0185 LUCA
GeneTreeiENSGT00390000000475
HOGENOMiHOG000111561
InParanoidiQ9XVP0
KOiK02958
OMAiVIRTHCR
OrthoDBiEOG091G0ZRG
PhylomeDBiQ9XVP0

Enzyme and pathway databases

ReactomeiR-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-CEL-72649 Translation initiation complex formation
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-CEL-72702 Ribosomal scanning and start codon recognition
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9XVP0

Gene expression databases

BgeeiWBGene00004484 Expressed in 5 organ(s), highest expression level in material anatomical entity

Family and domain databases

Gene3Di3.30.860.20, 1 hit
HAMAPiMF_00531 Ribosomal_S19, 1 hit
InterProiView protein in InterPro
IPR002222 Ribosomal_S19
IPR020934 Ribosomal_S19_CS
IPR023575 Ribosomal_S19_SF
IPR005713 Ribosomal_S19A/S15e
PANTHERiPTHR11880 PTHR11880, 1 hit
PfamiView protein in Pfam
PF00203 Ribosomal_S19, 1 hit
PIRSFiPIRSF002144 Ribosomal_S19, 1 hit
PRINTSiPR00975 RIBOSOMALS19
SUPFAMiSSF54570 SSF54570, 1 hit
TIGRFAMsiTIGR01025 uS19_arch, 1 hit
PROSITEiView protein in PROSITE
PS00323 RIBOSOMAL_S19, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS15_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9XVP0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: January 23, 2007
Last modified: December 5, 2018
This is version 128 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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