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Protein

40S ribosomal protein S15

Gene

rps-15

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Negatively regulates lifespan.1 Publication

GO - Molecular functioni

GO - Biological processi

  • determination of adult lifespan Source: WormBase
  • ribosomal small subunit assembly Source: GO_Central
  • translation Source: InterPro

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-CEL-72702 Ribosomal scanning and start codon recognition
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S15
Gene namesi
Name:rps-15Imported
ORF Names:F36A2.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF36A2.6 ; CE09945 ; WBGene00004484 ; rps-15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001300372 – 15140S ribosomal protein S15Add BLAST150

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanine1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9XVP0
PaxDbiQ9XVP0
PeptideAtlasiQ9XVP0
PRIDEiQ9XVP0

PTM databases

iPTMnetiQ9XVP0

Expressioni

Gene expression databases

BgeeiWBGene00004484

Interactioni

Protein-protein interaction databases

BioGridi38126, 10 interactors
IntActiQ9XVP0, 12 interactors
STRINGi6239.F36A2.6.1

Structurei

3D structure databases

ProteinModelPortaliQ9XVP0
SMRiQ9XVP0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uS19 family.Sequence analysis

Phylogenomic databases

eggNOGiKOG0898 Eukaryota
COG0185 LUCA
GeneTreeiENSGT00390000000475
HOGENOMiHOG000111561
InParanoidiQ9XVP0
KOiK02958
OMAiVIRTHCR
OrthoDBiEOG091G0ZRG
PhylomeDBiQ9XVP0

Family and domain databases

Gene3Di3.30.860.20, 1 hit
HAMAPiMF_00531 Ribosomal_S19, 1 hit
InterProiView protein in InterPro
IPR002222 Ribosomal_S19
IPR020934 Ribosomal_S19_CS
IPR023575 Ribosomal_S19_SF
IPR005713 Ribosomal_S19A/S15e
PANTHERiPTHR11880 PTHR11880, 1 hit
PfamiView protein in Pfam
PF00203 Ribosomal_S19, 1 hit
PIRSFiPIRSF002144 Ribosomal_S19, 1 hit
PRINTSiPR00975 RIBOSOMALS19
SUPFAMiSSF54570 SSF54570, 1 hit
TIGRFAMsiTIGR01025 uS19_arch, 1 hit
PROSITEiView protein in PROSITE
PS00323 RIBOSOMAL_S19, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9XVP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATQDDAHLA ELKKKRTFRK FMYRGVDLDQ LLDMSREQFT KLLPCRMRRR
60 70 80 90 100
LDRGLKRKHL ALIAKVQKAK KAAGVLEKPA TVKTHLRDMI ILPELVGGVI
110 120 130 140 150
GIYNGKVFNQ TEIKPEMIGF YLGEFAISYK PVKHGRPGIG ATHSSRFIPL

K
Length:151
Mass (Da):17,244
Last modified:January 23, 2007 - v3
Checksum:i146D97D8669C100C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z81077 Genomic DNA Translation: CAB03065.1
PIRiT21828
RefSeqiNP_492384.1, NM_059983.5
UniGeneiCel.8614

Genome annotation databases

EnsemblMetazoaiF36A2.6; F36A2.6; WBGene00004484
GeneIDi172693
KEGGicel:CELE_F36A2.6
UCSCiF36A2.6.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiRS15_CAEEL
AccessioniPrimary (citable) accession number: Q9XVP0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: January 23, 2007
Last modified: February 28, 2018
This is version 125 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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