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Protein

60S ribosomal protein L8

Gene

rpl-2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L8
Gene namesi
Name:rpl-2Imported
Synonyms:rpl-8Imported
ORF Names:B0250.1Imported
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiB0250.1 ; CE18478 ; WBGene00004413 ; rpl-2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001297511 – 26060S ribosomal protein L8Add BLAST260

Proteomic databases

EPDiQ9XVF7
PaxDbiQ9XVF7
PeptideAtlasiQ9XVF7
PRIDEiQ9XVF7

Expressioni

Gene expression databases

BgeeiWBGene00004413

Interactioni

Protein-protein interaction databases

BioGridi45300, 5 interactors
DIPiDIP-24785N
IntActiQ9XVF7, 2 interactors
STRINGi6239.B0250.1.2

Structurei

3D structure databases

ProteinModelPortaliQ9XVF7
SMRiQ9XVF7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2309 Eukaryota
COG0090 LUCA
GeneTreeiENSGT00390000009907
HOGENOMiHOG000232983
InParanoidiQ9XVF7
KOiK02938
OMAiHGYIKGV
OrthoDBiEOG091G0K1G
PhylomeDBiQ9XVF7

Family and domain databases

Gene3Di2.30.30.30, 1 hit
4.10.950.10, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR022666 Rbsml_prot_L2_RNA-bd_dom
IPR014722 Rib_L2_dom2
IPR002171 Ribosomal_L2
IPR022669 Ribosomal_L2_C
IPR022671 Ribosomal_L2_CS
IPR014726 Ribosomal_L2_dom3
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR13691 PTHR13691, 1 hit
PfamiView protein in Pfam
PF00181 Ribosomal_L2, 1 hit
PF03947 Ribosomal_L2_C, 1 hit
PIRSFiPIRSF002158 Ribosomal_L2, 1 hit
SMARTiView protein in SMART
SM01383 Ribosomal_L2, 1 hit
SM01382 Ribosomal_L2_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 1 hit
PROSITEiView protein in PROSITE
PS00467 RIBOSOMAL_L2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9XVF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRRIRIQRK GAGGIFKSHN KHRKGASKLR PLDYAERHGY IKGLVKDIIH
60 70 80 90 100
DPGRGAPLAI IAFRDPYKYK TVKTTVVAAE GMHTGQFIHC GAKAQIQIGN
110 120 130 140 150
IVPVGTLPEG TTICNVENKS GDRGVIARAS GNYATVIAHN PDTKKTRIRL
160 170 180 190 200
PSGAKKVVQS VNRAMIGLVA GGGRTDKPLL KAGRSYHKYK AKRNSWPRVR
210 220 230 240 250
GVAMNPVEHP HGGGNHQHIG HPSTVRRDAS AGKKVGLIAA RRTGRIRGGK
260
PVKFTKEENV
Length:260
Mass (Da):28,204
Last modified:November 1, 1999 - v1
Checksum:iEA8EA20430A79213
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z81453 Genomic DNA Translation: CAB03792.1
PIRiT18676
RefSeqiNP_507940.1, NM_075539.5
UniGeneiCel.9069

Genome annotation databases

EnsemblMetazoaiB0250.1; B0250.1; WBGene00004413
GeneIDi180343
KEGGicel:CELE_B0250.1
UCSCiB0250.1.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiRL8_CAEEL
AccessioniPrimary (citable) accession number: Q9XVF7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: November 1, 1999
Last modified: May 23, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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