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Protein

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase

Gene

glct-3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-alpha-D-glucuronate + [protein]-3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine = UDP + [protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine.UniRule annotation

Cofactori

Mn2+UniRule annotation

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

  • galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity Source: GO_Central
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
LigandManganeseUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

ReactomeiR-CEL-1971475 A tetrasaccharide linker sequence is required for GAG synthesis
UniPathwayi
UPA00378

Protein family/group databases

CAZyiGT43 Glycosyltransferase Family 43

Names & Taxonomyi

Protein namesi
Recommended name:
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferaseUniRule annotation (EC:2.4.1.135UniRule annotation)
Gene namesi
Name:glct-3Imported
ORF Names:CELE_T15D6.7Imported, T15D6.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiT15D6.7 ; CE42859 ; WBGene00011781 ; glct-3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatusUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ9XU73

Expressioni

Gene expression databases

BgeeiWBGene00011781 Expressed in 2 organ(s), highest expression level in multi-cellular organism

Interactioni

Protein-protein interaction databases

STRINGi6239.T15D6.7

Structurei

3D structure databases

ProteinModelPortaliQ9XU73
SMRiQ9XU73
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 43 family.UniRule annotation

Keywords - Domaini

Signal-anchorUniRule annotation, Transmembrane

Phylogenomic databases

eggNOGiKOG1476 Eukaryota
ENOG410XP79 LUCA
GeneTreeiENSGT00390000017640
InParanoidiQ9XU73
OMAiFPMDMAG
OrthoDBiEOG091G0G8P
PhylomeDBiQ9XU73

Family and domain databases

CDDicd00218 GlcAT-I, 1 hit
Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR005027 Glyco_trans_43
IPR029044 Nucleotide-diphossugar_trans
PANTHERiPTHR10896 PTHR10896, 1 hit
PfamiView protein in Pfam
PF03360 Glyco_transf_43, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit

Sequencei

Sequence statusi: Complete.

Q9XU73-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNRLGGFAI RWYAVGGLFG GSEIVSSILK DDPRILNFIV TYAFRIKPTS
60 70 80 90 100
PQDSGSNRMI IVITPTYKRI TRLADITRLA NTLSQVENLH WIVIEDGEST
110 120 130 140 150
IPNVQNILER SELLYTYVAH RTASGYPARG WYQRDMALKL IRTNPSQILG
160 170 180 190 200
EHEGEAVIYF ADDDNSYDLR LFEDYIRNVK KLGLWAVGLA GGAAVEAPNV
210 220 230 240 250
VNKKVTSFNF KWKSKRRFAV DMAGFAINLD YILNSSAVFG TECKRGDGAP
260 270 280 290 300
ETCLLEDLGF DLNDIEPFGY EKEKNNEILV WHTKTSYSGM KVKEAEKFGY

FVEP
Length:304
Mass (Da):34,320
Last modified:September 23, 2008 - v3
Checksum:i835BF2C4228E9B51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB05617.3
RefSeqiNP_493138.3, NM_060737.3
UniGeneiCel.27710

Genome annotation databases

EnsemblMetazoaiT15D6.7; T15D6.7; WBGene00011781
GeneIDi188533
KEGGicel:CELE_T15D6.7
UCSCiT15D6.7 c. elegans

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB05617.3
RefSeqiNP_493138.3, NM_060737.3
UniGeneiCel.27710

3D structure databases

ProteinModelPortaliQ9XU73
SMRiQ9XU73
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T15D6.7

Protein family/group databases

CAZyiGT43 Glycosyltransferase Family 43

Proteomic databases

PaxDbiQ9XU73

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT15D6.7; T15D6.7; WBGene00011781
GeneIDi188533
KEGGicel:CELE_T15D6.7
UCSCiT15D6.7 c. elegans

Organism-specific databases

CTDi188533
WormBaseiT15D6.7 ; CE42859 ; WBGene00011781 ; glct-3

Phylogenomic databases

eggNOGiKOG1476 Eukaryota
ENOG410XP79 LUCA
GeneTreeiENSGT00390000017640
InParanoidiQ9XU73
OMAiFPMDMAG
OrthoDBiEOG091G0G8P
PhylomeDBiQ9XU73

Enzyme and pathway databases

UniPathwayi
UPA00378

ReactomeiR-CEL-1971475 A tetrasaccharide linker sequence is required for GAG synthesis

Gene expression databases

BgeeiWBGene00011781 Expressed in 2 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd00218 GlcAT-I, 1 hit
Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR005027 Glyco_trans_43
IPR029044 Nucleotide-diphossugar_trans
PANTHERiPTHR10896 PTHR10896, 1 hit
PfamiView protein in Pfam
PF03360 Glyco_transf_43, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ9XU73_CAEEL
AccessioniPrimary (citable) accession number: Q9XU73
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: September 23, 2008
Last modified: November 7, 2018
This is version 116 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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