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Protein
Submitted name:

Proteasome Regulatory Particle, ATPase-like

Gene

rpt-6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
R-CEL-1236978 Cross-presentation of soluble exogenous antigens (endosomes)
R-CEL-174113 SCF-beta-TrCP mediated degradation of Emi1
R-CEL-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA
R-CEL-4608870 Asymmetric localization of PCP proteins
R-CEL-5632684 Hedgehog 'on' state
R-CEL-5668541 TNFR2 non-canonical NF-kB pathway
R-CEL-5689603 UCH proteinases
R-CEL-5689880 Ub-specific processing proteases
R-CEL-68949 Orc1 removal from chromatin
R-CEL-69229 Ubiquitin-dependent degradation of Cyclin D1
R-CEL-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
R-CEL-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-CEL-8939902 Regulation of RUNX2 expression and activity
R-CEL-8941858 Regulation of RUNX3 expression and activity
R-CEL-8948751 Regulation of PTEN stability and activity
R-CEL-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Submitted name:
Proteasome Regulatory Particle, ATPase-likeImported
Gene namesi
Name:rpt-6Imported
ORF Names:CELE_Y49E10.1Imported, Y49E10.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiY49E10.1 ; CE22219 ; WBGene00004506 ; rpt-6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

ProteasomeImported

PTM / Processingi

Proteomic databases

EPDiQ9XTT9
PaxDbiQ9XTT9
PeptideAtlasiQ9XTT9

Expressioni

Gene expression databases

BgeeiWBGene00004506

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-27139N
IntActiQ9XTT9, 4 interactors
STRINGi6239.Y49E10.1.1

Structurei

3D structure databases

ProteinModelPortaliQ9XTT9
SMRiQ9XTT9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini192 – 331AAAInterPro annotationAdd BLAST140

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili38 – 79Sequence analysisAdd BLAST42

Sequence similaritiesi

Belongs to the AAA ATPase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0728 Eukaryota
COG1222 LUCA
GeneTreeiENSGT00550000074947
HOGENOMiHOG000225143
InParanoidiQ9XTT9
KOiK03066
OMAiHGNNQEA
OrthoDBiEOG091G096W
PhylomeDBiQ9XTT9

Family and domain databases

InterProiView protein in InterPro
IPR005937 26S_Psome_P45-like
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR01242 26Sp45, 1 hit
PROSITEiView protein in PROSITE
PS00674 AAA, 1 hit

Sequencei

Sequence statusi: Complete.

Q9XTT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPPASTASS ADPSKPTAQK LTEESDEKTL RKYFSTKVDD AQQKVADKSQ
60 70 80 90 100
NVRRLQAQRN ELNTKVRMLK EELQQLHEQG SYVGEVSKAM DKKKVLVKVH
110 120 130 140 150
PEGKYVVDVD KSIDINSLNT GARVALRADS YALHKLLPNK VDPLVSLMMV
160 170 180 190 200
EKVPDSTYEM VGGLDKQIKE IKEVIELPVK HPELFDALGI AQPKGVLLFG
210 220 230 240 250
PPGTGKTLLA RAVAHHTECT FIRVSGSELV QKFIGEGARM VRELFVMARE
260 270 280 290 300
HAPSIIFMDE IDSIGSSRVE GSSGGDSEVQ RTMLELLNQL DGFEATKNIK
310 320 330 340 350
VIMATNRIDI LDPALLRPGR IDRKIEFPAP DEKARADILK IHSRKMNLMR
360 370 380 390 400
GINMAKIAEQ IPGASGAEVK SVCTEAGMFA LRERRIHVTQ EDFEMAVGKV
410
MQKDSEKNMS IKKLWK
Length:416
Mass (Da):46,250
Last modified:November 1, 1999 - v1
Checksum:i8F6E840EF99B1298
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CAB11558.1
PIRiT27048
RefSeqiNP_499609.1, NM_067208.4
UniGeneiCel.22621

Genome annotation databases

EnsemblMetazoaiY49E10.1; Y49E10.1; WBGene00004506
GeneIDi176661
KEGGicel:CELE_Y49E10.1
UCSCiY49E10.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ9XTT9_CAEEL
AccessioniPrimary (citable) accession number: Q9XTT9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: May 23, 2018
This is version 155 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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