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Protein

Palmitoyltransferase

Gene

Dnz1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:Dnz1Imported
Synonyms:DNZ1Imported
ORF Names:CG6627Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0027453 Dnz1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalUniRule annotationAdd BLAST21
Transmembranei38 – 57HelicalUniRule annotationAdd BLAST20
Transmembranei150 – 171HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9XTL3

Expressioni

Gene expression databases

ExpressionAtlasiQ9XTL3 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 182DHHCInterPro annotationAdd BLAST83

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311 Eukaryota
COG5273 LUCA
GeneTreeiENSGT00880000137864
OrthoDBiEOG091G0OGD

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9XTL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVFIRDPCGI ACLVVTYGAV LYADYVVIRW IILTTMPGSL WMSFHVVLFN
60 70 80 90 100
TVVFLLAMSH SKAVFSDPGT VPLPANRLDF SDLHTTNKNN PPPGNGHSSE
110 120 130 140 150
WTVCTRCETY RPPRAHHCRI CKRCIRRMDH HCPWINNCVG ERNQKYFLQF
160 170 180 190 200
LIYVALLSLY SIALIVGSWV WPCEECSQNV IETQLRMIHS GYPYAGVRRC
210 220 230 240 250
SACSLRPSWW TSCMRFCTTR RPWRRYSRRA PIVQIGASTS CWRMCSDADI
260 270
RRCGCCPAPV SIMPPANHDT PLLSHEV
Length:277
Mass (Da):31,691
Last modified:November 1, 1999 - v1
Checksum:i6812E7DFBAFD6254
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF121360 mRNA Translation: AAD34351.1
AF121361 Genomic DNA Translation: AAD37505.1

Genome annotation databases

EnsemblMetazoaiFBtr0080181; FBpp0079770; FBgn0027453

Similar proteinsi

Entry informationi

Entry nameiQ9XTL3_DROME
AccessioniPrimary (citable) accession number: Q9XTL3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: May 23, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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