UniProtKB - Q9XGR4 (2AB2A_ARATH)
Serine/threonine protein phosphatase 2A regulatory subunit B''alpha
B''ALPHA
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Calcium bindingi | 403 – 414 | PROSITE-ProRule annotationAdd BLAST | 12 |
GO - Molecular functioni
- calcium ion binding Source: InterPro
- protein phosphatase regulator activity Source: GO_Central
GO - Biological processi
- protein dephosphorylation Source: GO_Central
Keywordsi
Ligand | Calcium, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Serine/threonine protein phosphatase 2A regulatory subunit B''alphaShort name: AtB''alpha Short name: PP2A, B'' subunit, alpha isoform |
Gene namesi | Name:B''ALPHA Ordered Locus Names:At5g44090 ORF Names:MLN1.1 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G44090 |
TAIRi | locus:2167623, AT5G44090 |
Subcellular locationi
Mitochondrion
- mitochondrion Source: TAIR
Other locations
- protein phosphatase type 2A complex Source: GO_Central
Pathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000422787 | 1 – 538 | Serine/threonine protein phosphatase 2A regulatory subunit B''alphaAdd BLAST | 538 |
Proteomic databases
PaxDbi | Q9XGR4 |
PRIDEi | Q9XGR4 |
ProteomicsDBi | 245168 |
PTM databases
iPTMneti | Q9XGR4 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9XGR4, baseline and differential |
Genevisiblei | Q9XGR4, AT |
Interactioni
Subunit structurei
PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families) and cell signaling molecules.
Interacts with HMGR1L and HMGR1S (via N-terminus), but not with HMG2.
Interacts with PP2AA1.
1 PublicationProtein-protein interaction databases
BioGRIDi | 19682, 7 interactors |
IntActi | Q9XGR4, 7 interactors |
STRINGi | 3702.AT5G44090.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 177 – 212 | EF-hand 1PROSITE-ProRule annotationAdd BLAST | 36 | |
Domaini | 264 – 299 | EF-hand 2PROSITE-ProRule annotationAdd BLAST | 36 | |
Domaini | 390 – 425 | EF-hand 3PROSITE-ProRule annotationAdd BLAST | 36 |
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | KOG2562, Eukaryota |
HOGENOMi | CLU_019589_3_0_1 |
InParanoidi | Q9XGR4 |
OMAi | NLNIACG |
PhylomeDBi | Q9XGR4 |
Family and domain databases
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR041534, EF-hand_13 IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom |
Pfami | View protein in Pfam PF17958, EF-hand_13, 1 hit PF13499, EF-hand_7, 1 hit PF13833, EF-hand_8, 1 hit |
SUPFAMi | SSF47473, SSF47473, 2 hits |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
10 20 30 40 50
MEIDGGNDVQ ILDPELLQLP GLSPVSLKEN PHIAEELFSQ WLSLPETGRL
60 70 80 90 100
VKSLIDDTKS STPVSVSKNC TSLNVACGSA LPSVFLNSGT PPLSPRGSPG
110 120 130 140 150
SPRFSRQKTS PSLQSPLKSV REPKRQLIPQ FYFQHGRPPA KELREQCISM
160 170 180 190 200
VDQFFSNYID GLHMDEFKSI TKEVCKLPSF LSSVLFRKID TSGTGIVTRD
210 220 230 240 250
AFIKYWVDGH MLAMDVASQI YNILRQPGCK YLRQADFKPV LDELLTTHPG
260 270 280 290 300
LEFLRNTPEF QERYAETVIY RIFYYINRSG TGCITLRELK RGNLITAMQQ
310 320 330 340 350
VDEEDDINKV IRYFSYEHFY VIYCRFWELD GDHDFLIDKE NLIKYGNHAL
360 370 380 390 400
TYRIVDRIFS QVPRKFTSKV EGKMSYEDFA YFILAEEDKS SEPSLEYWFK
410 420 430 440 450
CIDLDGDGVI TPNEMQFFYE EQLHRMECIT QEPVLFEDIL CQIFDMIKPE
460 470 480 490 500
KENCITLQDL KASKLSGNIF NILFNLNKFM AFETRDPFLI RQERENPTLT
510 520 530
EWDRFAQREY VRLSMEEDVE EVSNGSADVW DEPLESPF
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8BH17 | A0A1P8BH17_ARATH | Calcium-binding EF-hand family prot... | At5g44090 | 573 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF165429 mRNA Translation: AAD45158.1 AB005239 Genomic DNA Translation: BAB10976.1 CP002688 Genomic DNA Translation: AED95057.1 AY099553 mRNA Translation: AAM20405.1 BT002124 mRNA Translation: AAN72135.1 AY462121 mRNA Translation: AAS44556.1 |
RefSeqi | NP_199222.1, NM_123776.4 |
Genome annotation databases
EnsemblPlantsi | AT5G44090.1; AT5G44090.1; AT5G44090 |
GeneIDi | 834432 |
Gramenei | AT5G44090.1; AT5G44090.1; AT5G44090 |
KEGGi | ath:AT5G44090 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF165429 mRNA Translation: AAD45158.1 AB005239 Genomic DNA Translation: BAB10976.1 CP002688 Genomic DNA Translation: AED95057.1 AY099553 mRNA Translation: AAM20405.1 BT002124 mRNA Translation: AAN72135.1 AY462121 mRNA Translation: AAS44556.1 |
RefSeqi | NP_199222.1, NM_123776.4 |
3D structure databases
SMRi | Q9XGR4 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 19682, 7 interactors |
IntActi | Q9XGR4, 7 interactors |
STRINGi | 3702.AT5G44090.1 |
PTM databases
iPTMneti | Q9XGR4 |
Proteomic databases
PaxDbi | Q9XGR4 |
PRIDEi | Q9XGR4 |
ProteomicsDBi | 245168 |
Genome annotation databases
EnsemblPlantsi | AT5G44090.1; AT5G44090.1; AT5G44090 |
GeneIDi | 834432 |
Gramenei | AT5G44090.1; AT5G44090.1; AT5G44090 |
KEGGi | ath:AT5G44090 |
Organism-specific databases
Araporti | AT5G44090 |
TAIRi | locus:2167623, AT5G44090 |
Phylogenomic databases
eggNOGi | KOG2562, Eukaryota |
HOGENOMi | CLU_019589_3_0_1 |
InParanoidi | Q9XGR4 |
OMAi | NLNIACG |
PhylomeDBi | Q9XGR4 |
Miscellaneous databases
PROi | PR:Q9XGR4 |
Gene expression databases
ExpressionAtlasi | Q9XGR4, baseline and differential |
Genevisiblei | Q9XGR4, AT |
Family and domain databases
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR041534, EF-hand_13 IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom |
Pfami | View protein in Pfam PF17958, EF-hand_13, 1 hit PF13499, EF-hand_7, 1 hit PF13833, EF-hand_8, 1 hit |
SUPFAMi | SSF47473, SSF47473, 2 hits |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | 2AB2A_ARATH | |
Accessioni | Q9XGR4Primary (citable) accession number: Q9XGR4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 26, 2013 |
Last sequence update: | November 1, 1999 | |
Last modified: | December 2, 2020 | |
This is version 132 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names