UniProtKB - Q9XEC7 (CRK37_ARATH)
Protein
Cysteine-rich receptor-like protein kinase 37
Gene
CRK37
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 373 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 470 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 351 – 359 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein serine/threonine kinase activity Source: GO_Central
- protein serine kinase activity Source: RHEA
- protein threonine kinase activity Source: RHEA
GO - Biological processi
- protein phosphorylation Source: GO_Central
Keywordsi
Molecular function | Kinase, Receptor, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Cysteine-rich receptor-like protein kinase 37 (EC:2.7.11.-)Short name: Cysteine-rich RLK37 |
Gene namesi | Name:CRK37 Ordered Locus Names:At4g04500 ORF Names:T26N6.11 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G04500 |
TAIRi | locus:2137144, AT4G04500 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 27 – 287 | ExtracellularSequence analysisAdd BLAST | 261 | |
Transmembranei | 288 – 308 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 309 – 646 | CytoplasmicSequence analysisAdd BLAST | 338 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 26 | Sequence analysisAdd BLAST | 26 | |
ChainiPRO_0000295084 | 27 – 646 | Cysteine-rich receptor-like protein kinase 37Add BLAST | 620 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 62 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 129 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 169 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 180 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 418 | PhosphotyrosineBy similarity | 1 | |
Modified residuei | 474 | PhosphoserineBy similarity | 1 | |
Modified residuei | 510 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 518 | PhosphotyrosineBy similarity | 1 |
Keywords - PTMi
Glycoprotein, PhosphoproteinProteomic databases
PaxDbi | Q9XEC7 |
PRIDEi | Q9XEC7 |
ProteomicsDBi | 222763 |
PTM databases
iPTMneti | Q9XEC7 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9XEC7, baseline and differential |
Genevisiblei | Q9XEC7, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 11091, 10 interactors |
IntActi | Q9XEC7, 10 interactors |
STRINGi | 3702.AT4G04500.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 27 – 132 | Gnk2-homologous 1PROSITE-ProRule annotationAdd BLAST | 106 | |
Domaini | 142 – 252 | Gnk2-homologous 2PROSITE-ProRule annotationAdd BLAST | 111 | |
Domaini | 345 – 626 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 282 |
Sequence similaritiesi
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.PROSITE-ProRule annotation
Keywords - Domaini
Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502SE86, Eukaryota |
HOGENOMi | CLU_000288_35_2_1 |
InParanoidi | Q9XEC7 |
OMAi | WRVEESD |
OrthoDBi | 684563at2759 |
PhylomeDBi | Q9XEC7 |
Family and domain databases
Gene3Di | 3.30.430.20, 2 hits |
InterProi | View protein in InterPro IPR002902, GNK2 IPR038408, GNK2_sf IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit PF01657, Stress-antifung, 2 hits |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS51473, GNK2, 2 hits PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9XEC7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKSCVVTSS FSLLLLFLQT LKYVHAGFIC YGDFFNVNYG VSRTYLFSSL
60 70 80 90 100
PSNVVSNGGF YNASFGRDSK NNRVHVVALC RRGYEKQACK TCLEHVIEDT
110 120 130 140 150
KSKCPRQKES FSWVTDEFDD VSCSLRYTNH STLGKLELLP NTINPNPNSI
160 170 180 190 200
DSKFNNMAMF SQEWIAMVNR TLEAASTAEN SSVLKYYSAT RTEFTQISDV
210 220 230 240 250
YALMQCVPDL SPGNCKRCLR ECVNDFQKQF WGRQGGGVSR PSCYFRWDLY
260 270 280 290 300
PYYRAFDNVV RVPAPPPQAS STIIDYGRDE KSFQGSNIAI IVVPSVINLI
310 320 330 340 350
IFVVLIFSWK RKQSHTIIND VFDSNNGQSM LRFDLRMIVT ATNNFSLENK
360 370 380 390 400
LGQGGFGSVY KGILPSGQEI AVKRLRKGSG QGGMEFKNEV LLLTRLQHRN
410 420 430 440 450
LVKLLGFCNE KDEEILVYEF VPNSSLDHFI FDEEKRRVLT WDVRYTIIEG
460 470 480 490 500
VARGLLYLHE DSQLRIIHRD LKASNILLDA EMNPKVADFG MARLFDMDET
510 520 530 540 550
RGQTSRVVGT YGYMAPEYAT YGQFSTKSDV YSFGVMLLEM ISGKSNKKLE
560 570 580 590 600
KEEEEEEEEL PAFVWKRWIE GRFAEIIDPL AAPSNNISIN EVMKLIHIGL
610 620 630 640
LCVQEDISKR PSINSILFWL ERHATITMPV PTPVAYLTRP SLSLGH
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8B4N1 | A0A1P8B4N1_ARATH | Cysteine-rich RLK (RECEPTOR-like pr... | CRK37 At4g04500, T26N6.11, T26N6_11 | 510 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF076243 Genomic DNA Translation: AAD29762.1 AL161500 Genomic DNA Translation: CAB77918.1 CP002687 Genomic DNA Translation: AEE82395.1 |
PIRi | G85056 |
RefSeqi | NP_192359.1, NM_116688.3 |
Genome annotation databases
EnsemblPlantsi | AT4G04500.1; AT4G04500.1; AT4G04500 |
GeneIDi | 825780 |
Gramenei | AT4G04500.1; AT4G04500.1; AT4G04500 |
KEGGi | ath:AT4G04500 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF076243 Genomic DNA Translation: AAD29762.1 AL161500 Genomic DNA Translation: CAB77918.1 CP002687 Genomic DNA Translation: AEE82395.1 |
PIRi | G85056 |
RefSeqi | NP_192359.1, NM_116688.3 |
3D structure databases
SMRi | Q9XEC7 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 11091, 10 interactors |
IntActi | Q9XEC7, 10 interactors |
STRINGi | 3702.AT4G04500.1 |
PTM databases
iPTMneti | Q9XEC7 |
Proteomic databases
PaxDbi | Q9XEC7 |
PRIDEi | Q9XEC7 |
ProteomicsDBi | 222763 |
Genome annotation databases
EnsemblPlantsi | AT4G04500.1; AT4G04500.1; AT4G04500 |
GeneIDi | 825780 |
Gramenei | AT4G04500.1; AT4G04500.1; AT4G04500 |
KEGGi | ath:AT4G04500 |
Organism-specific databases
Araporti | AT4G04500 |
TAIRi | locus:2137144, AT4G04500 |
Phylogenomic databases
eggNOGi | ENOG502SE86, Eukaryota |
HOGENOMi | CLU_000288_35_2_1 |
InParanoidi | Q9XEC7 |
OMAi | WRVEESD |
OrthoDBi | 684563at2759 |
PhylomeDBi | Q9XEC7 |
Miscellaneous databases
PROi | PR:Q9XEC7 |
Gene expression databases
ExpressionAtlasi | Q9XEC7, baseline and differential |
Genevisiblei | Q9XEC7, AT |
Family and domain databases
Gene3Di | 3.30.430.20, 2 hits |
InterProi | View protein in InterPro IPR002902, GNK2 IPR038408, GNK2_sf IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit PF01657, Stress-antifung, 2 hits |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS51473, GNK2, 2 hits PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CRK37_ARATH | |
Accessioni | Q9XEC7Primary (citable) accession number: Q9XEC7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 10, 2007 |
Last sequence update: | November 1, 1999 | |
Last modified: | April 7, 2021 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families