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Entry version 137 (02 Jun 2021)
Sequence version 1 (01 Nov 1999)
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Protein
Submitted name:

PadR family transcriptional regulator

Gene

aphA

Organism
Vibrio cholerae
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
PadR family transcriptional regulatorImported
Submitted name:
Transcriptional regulatorImported
Submitted name:
Uncharacterized protein aphAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:aphAImported
ORF Names:C9J66_06975Imported, D6U24_09765Imported, ERS013165_01671Imported, ERS013166_01505Imported, ERS013173_02279Imported, ERS013198_02052Imported, ERS013199_03231Imported, ERS013200_00061Imported, ERS013201_00878Imported, ERS013202_02088Imported, EYB64_07510Imported, F0315_06550Imported, F0M16_05160Imported, FKR41_12085Imported, FLM02_07620Imported, FXE88_03380Imported, FXF03_07650Imported, HPY05_01240Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiVibrio choleraeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri666 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000043247 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000319979 Componenti: Unassembled WGS sequence
  • UP000322743 Componenti: Chromosome 1
  • UP000471242 Componenti: Unassembled WGS sequence
  • UP000044247 Componenti: Unassembled WGS sequence
  • UP000323225 Componenti: Unassembled WGS sequence
  • UP000043560 Componenti: Unassembled WGS sequence
  • UP000044806 Componenti: Unassembled WGS sequence
  • UP000509695 Componenti: Chromosome 1
  • UP000041770 Componenti: Unassembled WGS sequence
  • UP000248087 Componenti: Unassembled WGS sequence
  • UP000461489 Componenti: Unassembled WGS sequence
  • UP000046067 Componenti: Unassembled WGS sequence
  • UP000294145 Componenti: Unassembled WGS sequence
  • UP000045578 Componenti: Unassembled WGS sequence
  • UP000323819 Componenti: Unassembled WGS sequence
  • UP000039886 Componenti: Unassembled WGS sequence
  • UP000322999 Componenti: Unassembled WGS sequence

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Miscellaneous databases

Pathogen-Host Interaction database

More...
PHI-basei
PHI:711

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini7 – 80PadRInterPro annotationAdd BLAST74
Domaini92 – 176Vir_act_alpha_CInterPro annotationAdd BLAST85

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili115 – 135Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
1629615at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018309, Tscrpt_reg_PadR_C
IPR005149, Tscrpt_reg_PadR_N
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03551, PadR, 1 hit
PF10400, Vir_act_alpha_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9X399-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLPHVILTV LSTRDATGYD ITKEFSASIG YFWKASHQQV YRELNKMGEQ
60 70 80 90 100
GLVTCVLEPQ EGKPDRKVYS ITQAGRSALG EWFDQPTAHP TVRDEFSAKL
110 120 130 140 150
MACSVQSAEP YRLQLAELVE ESRKLVAHYQ EIEAAYYANP AVLDKQQRLE
160 170
RLTLRRNLLV RQAWIQWADE VLAELNAMA
Length:179
Mass (Da):20,429
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDDB10F84CA31D8CB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF065442 Genomic DNA Translation: AAD31382.1
CWPA01000007 Genomic DNA Translation: CSA31496.1
CWOW01000007 Genomic DNA Translation: CSA47353.1
CWPD01000011 Genomic DNA Translation: CSB01311.1
CWQJ01000004 Genomic DNA Translation: CSB76262.1
CWQY01000001 Genomic DNA Translation: CSB92877.1
CWQA01000010 Genomic DNA Translation: CSC02760.1
CWQG01000007 Genomic DNA Translation: CSC10968.1
CWQX01000067 Genomic DNA Translation: CSC95030.1
VUAA01000004 Genomic DNA Translation: KAA1255739.1
QZRB01000011 Genomic DNA Translation: MVD23644.1
VHOF01000006 Genomic DNA Translation: NAO20110.1
PYRF01000005 Genomic DNA Translation: PYC83587.1
CP043557 Genomic DNA Translation: QEO44971.1
CP053810 Genomic DNA Translation: QKU73655.1
SISP01000009 Genomic DNA Translation: TBM43587.1
VIOS01000019 Genomic DNA Translation: TQP15265.1
VSIJ01000023 Genomic DNA Translation: TXX66182.1
VSHU01000009 Genomic DNA Translation: TXY66825.1

Protein sequence database of the Protein Information Resource

More...
PIRi
E82049

NCBI Reference Sequences

More...
RefSeqi
WP_000056565.1, NZ_WYCS01000014.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AKO76102; AKO76102; EN12_12860
CPR22881; CPR22881; CPR22881
KFE27562; KFE27562; DN30_1763
ORP16026; ORP16026; B7947_01545
PYC83587; PYC83587; C9J66_06975

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57741247

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vcq:EN18_16260
vcx:VAA049_252
vcz:VAB027_244

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|666.1965.peg.722

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF065442 Genomic DNA Translation: AAD31382.1
CWPA01000007 Genomic DNA Translation: CSA31496.1
CWOW01000007 Genomic DNA Translation: CSA47353.1
CWPD01000011 Genomic DNA Translation: CSB01311.1
CWQJ01000004 Genomic DNA Translation: CSB76262.1
CWQY01000001 Genomic DNA Translation: CSB92877.1
CWQA01000010 Genomic DNA Translation: CSC02760.1
CWQG01000007 Genomic DNA Translation: CSC10968.1
CWQX01000067 Genomic DNA Translation: CSC95030.1
VUAA01000004 Genomic DNA Translation: KAA1255739.1
QZRB01000011 Genomic DNA Translation: MVD23644.1
VHOF01000006 Genomic DNA Translation: NAO20110.1
PYRF01000005 Genomic DNA Translation: PYC83587.1
CP043557 Genomic DNA Translation: QEO44971.1
CP053810 Genomic DNA Translation: QKU73655.1
SISP01000009 Genomic DNA Translation: TBM43587.1
VIOS01000019 Genomic DNA Translation: TQP15265.1
VSIJ01000023 Genomic DNA Translation: TXX66182.1
VSHU01000009 Genomic DNA Translation: TXY66825.1
PIRiE82049
RefSeqiWP_000056565.1, NZ_WYCS01000014.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YG2X-ray2.20A1-179[»]
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...
PDBe-KBiSearch...

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
2615664

Genome annotation databases

EnsemblBacteriaiAKO76102; AKO76102; EN12_12860
CPR22881; CPR22881; CPR22881
KFE27562; KFE27562; DN30_1763
ORP16026; ORP16026; B7947_01545
PYC83587; PYC83587; C9J66_06975
GeneIDi57741247
KEGGivcq:EN18_16260
vcx:VAA049_252
vcz:VAB027_244
PATRICifig|666.1965.peg.722

Phylogenomic databases

OrthoDBi1629615at2

Miscellaneous databases

PHI-baseiPHI:711

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR018309, Tscrpt_reg_PadR_C
IPR005149, Tscrpt_reg_PadR_N
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF03551, PadR, 1 hit
PF10400, Vir_act_alpha_C, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9X399_VIBCL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9X399
Secondary accession number(s): Q7DCS8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: June 2, 2021
This is version 137 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
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