UniProtKB - Q9X286 (NUSB_THEMA)
Protein
Transcription antitermination protein NusB
Gene
nusB
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Functioni
Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.UniRule annotation
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
GO - Biological processi
- DNA-templated transcription, termination Source: UniProtKB-UniRule
- transcription antitermination Source: UniProtKB-KW
Keywordsi
Molecular function | RNA-binding |
Biological process | Transcription, Transcription antitermination, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription antitermination protein NusBUniRule annotationAlternative name(s): Antitermination factor NusB1 PublicationUniRule annotation |
Gene namesi | Name:nusBUniRule annotation Ordered Locus Names:TM_1765 |
Organismi | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) |
Taxonomic identifieri | 243274 [NCBI] |
Taxonomic lineagei | Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000176599 | 1 – 142 | Transcription antitermination protein NusBAdd BLAST | 142 |
Interactioni
Subunit structurei
Monomer or homodimer; in equilibrium, with a preference for the monomer. Dimerization may be employed to package NusB in an inactive form until recruitment into antitermination complexes.
1 PublicationProtein-protein interaction databases
STRINGi | 243274.THEMA_05400 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q9X286 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q9X286 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG0781, Bacteria |
InParanoidi | Q9X286 |
OMAi | DRMPVVD |
OrthoDBi | 1574817at2 |
Family and domain databases
Gene3Di | 1.10.940.10, 1 hit |
HAMAPi | MF_00073, NusB, 1 hit |
InterProi | View protein in InterPro IPR035926, NusB-like_sf IPR011605, NusB_fam IPR006027, NusB_RsmB_TIM44 |
PANTHERi | PTHR11078, PTHR11078, 1 hit |
Pfami | View protein in Pfam PF01029, NusB, 1 hit |
SUPFAMi | SSF48013, SSF48013, 1 hit |
TIGRFAMsi | TIGR01951, nusB, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9X286-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKTPRRRMRL AVFKALFQHE FRRDEDLEQI LEEILDETYD KKAKEDARRY
60 70 80 90 100
IRGIKENLSM IDDLISRYLE KWSLNRLSVV DRNVLRLATY ELLFEKDIPI
110 120 130 140
EVTIDEAIEI AKRYGTENSG KFVNGILDRI AKEHAPKEKF EL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000512 Genomic DNA Translation: AAD36829.1 |
PIRi | D72212 |
RefSeqi | NP_229562.1, NC_000853.1 WP_004082311.1, NZ_CP011107.1 |
Genome annotation databases
EnsemblBacteriai | AAD36829; AAD36829; TM_1765 |
KEGGi | tma:TM1765 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000512 Genomic DNA Translation: AAD36829.1 |
PIRi | D72212 |
RefSeqi | NP_229562.1, NC_000853.1 WP_004082311.1, NZ_CP011107.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1TZT | X-ray | 1.55 | A/B | 1-142 | [»] | |
1TZU | X-ray | 1.85 | A | 1-142 | [»] | |
1TZV | X-ray | 1.35 | A | 1-142 | [»] | |
1TZW | X-ray | 1.60 | A | 1-142 | [»] | |
1TZX | X-ray | 1.72 | A/B | 1-142 | [»] | |
SMRi | Q9X286 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 243274.THEMA_05400 |
Chemistry databases
DrugBanki | DB04272, Citric acid |
Genome annotation databases
EnsemblBacteriai | AAD36829; AAD36829; TM_1765 |
KEGGi | tma:TM1765 |
Phylogenomic databases
eggNOGi | COG0781, Bacteria |
InParanoidi | Q9X286 |
OMAi | DRMPVVD |
OrthoDBi | 1574817at2 |
Miscellaneous databases
EvolutionaryTracei | Q9X286 |
Family and domain databases
Gene3Di | 1.10.940.10, 1 hit |
HAMAPi | MF_00073, NusB, 1 hit |
InterProi | View protein in InterPro IPR035926, NusB-like_sf IPR011605, NusB_fam IPR006027, NusB_RsmB_TIM44 |
PANTHERi | PTHR11078, PTHR11078, 1 hit |
Pfami | View protein in Pfam PF01029, NusB, 1 hit |
SUPFAMi | SSF48013, SSF48013, 1 hit |
TIGRFAMsi | TIGR01951, nusB, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | NUSB_THEMA | |
Accessioni | Q9X286Primary (citable) accession number: Q9X286 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | November 1, 1999 | |
Last modified: | December 2, 2020 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families