UniProtKB - Q9WZW5 (Q9WZW5_THEMA)
Protein
Protein-export membrane protein SecF
Gene
secF
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Functioni
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation
GO - Molecular functioni
GO - Biological processi
- intracellular protein transmembrane transport Source: UniProtKB-UniRule
- protein targeting Source: UniProtKB-UniRule
- protein transport Source: GO_Central
- protein transport by the Sec complex Source: UniProtKB-UniRule
Keywordsi
Biological process | Protein transport, TranslocationUniRule annotationARBA annotation, Transport |
Enzyme and pathway databases
BioCyci | TMAR243274:G1H0Q-66-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Protein-export membrane protein SecFUniRule annotation |
Gene namesi | Name:secFUniRule annotation Ordered Locus Names:TM_0861Imported |
Organismi | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported |
Taxonomic identifieri | 243274 [NCBI] |
Taxonomic lineagei | Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 31 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 136 – 154 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 161 – 182 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 188 – 208 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 240 – 258 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 264 – 288 | HelicalUniRule annotationAdd BLAST | 25 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membraneUniRule annotation, Cell membrane, MembraneInteractioni
Subunit structurei
Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
UniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 154 – 289 | SSDInterPro annotationAdd BLAST | 136 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
OMAi | AFEWRMA |
OrthoDBi | 410730at2 |
Family and domain databases
HAMAPi | MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS IPR005665, SecF_bac IPR000731, SSD |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF07549, Sec_GG, 1 hit PF02355, SecD_SecF, 1 hit |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00916, 2A0604s01, 1 hit TIGR00966, 3a0501s07, 1 hit |
PROSITEi | View protein in PROSITE PS50156, SSD, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9WZW5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRKEIDFMGK SKIFITISLI LIAISIVSIF TKGFNFGVEF TGGSEIIVRF
60 70 80 90 100
ENKEVTENDI RAAISQISEE FANARIVEVR SAGDPSNVQK YSIIVPKTYE
110 120 130 140 150
PDEKQKIQEE MEKLLSGKVV SFNEISGTAA EEIRRGTWTA ILVALVVLLI
160 170 180 190 200
YITIRFRFIF GVAAVVALIH DVLITMGFFS LFGYEINVAA VAAFLTLLGY
210 220 230 240 250
SLNDTIVLSD RIRENMRRYR GRNMVNIVNM SINQVLARTI NTSLTTFFVV
260 270 280 290
FVLLLFAGNA VKPFAFGMTV GTIVGTYSSL YVASPIIVKW TKQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000512 Genomic DNA Translation: AAD35943.1 |
PIRi | F72325 |
RefSeqi | NP_228670.1, NC_000853.1 WP_004080745.1, NZ_CP011107.1 |
Genome annotation databases
EnsemblBacteriai | AAD35943; AAD35943; TM_0861 AGL49788; AGL49788; Tmari_0863 |
KEGGi | tma:TM0861 tmi:THEMA_00330 tmw:THMA_0883 |
PATRICi | fig|243274.17.peg.862 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000512 Genomic DNA Translation: AAD35943.1 |
PIRi | F72325 |
RefSeqi | NP_228670.1, NC_000853.1 WP_004080745.1, NZ_CP011107.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
EnsemblBacteriai | AAD35943; AAD35943; TM_0861 AGL49788; AGL49788; Tmari_0863 |
KEGGi | tma:TM0861 tmi:THEMA_00330 tmw:THMA_0883 |
PATRICi | fig|243274.17.peg.862 |
Phylogenomic databases
OMAi | AFEWRMA |
OrthoDBi | 410730at2 |
Enzyme and pathway databases
BioCyci | TMAR243274:G1H0Q-66-MONOMER |
Family and domain databases
HAMAPi | MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR022646, SecD/SecF_CS IPR005665, SecF_bac IPR000731, SSD |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF07549, Sec_GG, 1 hit PF02355, SecD_SecF, 1 hit |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00916, 2A0604s01, 1 hit TIGR00966, 3a0501s07, 1 hit |
PROSITEi | View protein in PROSITE PS50156, SSD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9WZW5_THEMA | |
Accessioni | Q9WZW5Primary (citable) accession number: Q9WZW5 Secondary accession number(s): G4FCW3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1999 |
Last sequence update: | November 1, 1999 | |
Last modified: | December 2, 2020 | |
This is version 120 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |