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Protein

Polyamine-modulated factor 1-binding protein 1

Gene

Pmfbp1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in sperm morphology especially the sperm tail and consequently affect fertility. May also be involved in the general organization of cellular cytoskeleton.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Polyamine-modulated factor 1-binding protein 1
Short name:
PMF-1-binding protein
Alternative name(s):
Sperm tail-associated protein
Gene namesi
Name:Pmfbp1
Synonyms:Stap
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1930136 Pmfbp1

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003046201 – 1022Polyamine-modulated factor 1-binding protein 1Add BLAST1022

Proteomic databases

MaxQBiQ9WVQ0
PaxDbiQ9WVQ0
PRIDEiQ9WVQ0

PTM databases

iPTMnetiQ9WVQ0
PhosphoSitePlusiQ9WVQ0

Expressioni

Tissue specificityi

Located at the tail of elongated spermatids.1 Publication

Gene expression databases

BgeeiENSMUSG00000031727 Expressed in 43 organ(s), highest expression level in testis
CleanExiMM_PMFBP1
ExpressionAtlasiQ9WVQ0 baseline and differential
GenevisibleiQ9WVQ0 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034162

Structurei

3D structure databases

ProteinModelPortaliQ9WVQ0
SMRiQ9WVQ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili89 – 121Sequence analysisAdd BLAST33
Coiled coili169 – 281Sequence analysisAdd BLAST113
Coiled coili312 – 377Sequence analysisAdd BLAST66
Coiled coili411 – 732Sequence analysisAdd BLAST322
Coiled coili758 – 968Sequence analysisAdd BLAST211

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IV92 Eukaryota
ENOG4112C9M LUCA
GeneTreeiENSGT00390000012700
HOGENOMiHOG000060143
HOVERGENiHBG072641
InParanoidiQ9WVQ0
OMAiQENQLCV
OrthoDBiEOG091G02GR
PhylomeDBiQ9WVQ0
TreeFamiTF336266

Family and domain databases

InterProiView protein in InterPro
IPR037391 PMF1-bd
PANTHERiPTHR18881 PTHR18881, 1 hit

Sequencei

Sequence statusi: Complete.

Q9WVQ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLKLKGELRT AKGLKNEAGE RDRDVSNLNS KLLSLQLDIK NLHDVCKRQG
60 70 80 90 100
KTLQENQLCV EEAMLKANHN KKQAQTLVFT DNQMDFRVNK QYHLRQLQQL
110 120 130 140 150
KKKLLTLQQE LEFRTQELQA SYCSLLQYQS ILEKQTSDLL VLHRHCKLKE
160 170 180 190 200
DEVILYEEEM GNHSKSTGEK LHLAQEQLAL AGDKILSLER SLNLYRDKYQ
210 220 230 240 250
TSLSNIELLE CQVKMLEGEL SGLIGQDPEN KGDHPKVRIY TSPCVIQEHQ
260 270 280 290 300
ETLKRLSEVW QKVSEQDDLI QELRNKLACS NSLVLEREEA LIKLQAEFAS
310 320 330 340 350
YTATHRHPPT SSEDCEDITK ILKHLQEQKD SQCLHVEEYQ NLVKDLRMEL
360 370 380 390 400
EAVSEQKKKI MKDMMKLELD LHGLREETSC VIEKKDKETV FLQYRLQDLQ
410 420 430 440 450
QQYTESQKLS LKKDKLLQDK DERLHELEKN LMQVQNSLRE KEAELEKLQC
460 470 480 490 500
TTKELDTSLQ EARQSTSKID CEALRAEIQK LKDSLEEARE QLKVSDQNLT
510 520 530 540 550
QSKEEAHLSA SSLEDAHRKI ENCLLQDKQK EEVIKDLQSQ LHKLQKESSK
560 570 580 590 600
IEEERKHNRQ RLQELSSELS EGQRRLSNAE KEKSLLQKTL DEDEKKIDEL
610 620 630 640 650
FHSTQVSEQK QRELTNSIRK LEEELLEIKG LLEEKREQLK KSKEQEKALE
660 670 680 690 700
EEIEALRQEA KRKEKMAKEH LRKLDEEKEN LQAELTSRSS HLDSSLNKYN
710 720 730 740 750
SSQKVIQELN AEIARQKDSI MILQTQLDSA IQKEKNCFQN MVSKEAYEEL
760 770 780 790 800
VRKSGNCQDD LTQALEKLTQ ATSETKSLNR SLQQTQERKA QLEDEIAAYE
810 820 830 840 850
ERMKKLNMEL KKLQGFQQQS EQEVHNFDKK LEEMSNQVLQ WQRQHQSDLK
860 870 880 890 900
MLAAKESQLR EFQEEMATLR ESLLADEKEP YSPPAKLTPK ETCRHHREND
910 920 930 940 950
QIMNNVEQWA KEQKIANEKL GNKLREQVKY IAKLTGEKDH LHNVMVHLQQ
960 970 980 990 1000
ENKKLKNEIE EKKLKAGNPR ICVKAFPPNK LEPSQKGKLC CALGWRGIPQ
1010 1020
DLTPKTDHKY MGLPHSSGSS YC
Length:1,022
Mass (Da):119,401
Last modified:November 1, 1999 - v1
Checksum:i4C41FE64AFCD984A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB029919 mRNA Translation: BAA82514.1
CCDSiCCDS40468.1
RefSeqiNP_064322.1, NM_019938.3
XP_006531277.1, XM_006531214.3
UniGeneiMm.42166

Genome annotation databases

EnsembliENSMUST00000034162; ENSMUSP00000034162; ENSMUSG00000031727
GeneIDi56523
KEGGimmu:56523
UCSCiuc009nii.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB029919 mRNA Translation: BAA82514.1
CCDSiCCDS40468.1
RefSeqiNP_064322.1, NM_019938.3
XP_006531277.1, XM_006531214.3
UniGeneiMm.42166

3D structure databases

ProteinModelPortaliQ9WVQ0
SMRiQ9WVQ0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034162

PTM databases

iPTMnetiQ9WVQ0
PhosphoSitePlusiQ9WVQ0

Proteomic databases

MaxQBiQ9WVQ0
PaxDbiQ9WVQ0
PRIDEiQ9WVQ0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000034162; ENSMUSP00000034162; ENSMUSG00000031727
GeneIDi56523
KEGGimmu:56523
UCSCiuc009nii.2 mouse

Organism-specific databases

CTDi83449
MGIiMGI:1930136 Pmfbp1

Phylogenomic databases

eggNOGiENOG410IV92 Eukaryota
ENOG4112C9M LUCA
GeneTreeiENSGT00390000012700
HOGENOMiHOG000060143
HOVERGENiHBG072641
InParanoidiQ9WVQ0
OMAiQENQLCV
OrthoDBiEOG091G02GR
PhylomeDBiQ9WVQ0
TreeFamiTF336266

Miscellaneous databases

ChiTaRSiPmfbp1 mouse
PROiPR:Q9WVQ0
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031727 Expressed in 43 organ(s), highest expression level in testis
CleanExiMM_PMFBP1
ExpressionAtlasiQ9WVQ0 baseline and differential
GenevisibleiQ9WVQ0 MM

Family and domain databases

InterProiView protein in InterPro
IPR037391 PMF1-bd
PANTHERiPTHR18881 PTHR18881, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPMFBP_MOUSE
AccessioniPrimary (citable) accession number: Q9WVQ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 1, 1999
Last modified: November 7, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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