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Protein
Submitted name:

Forkhead protein FKHR1

Gene

Foxo1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi157 – 251Fork-headPROSITE-ProRule annotationAdd BLAST95

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscriptionSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead protein FKHR1Imported
Gene namesi
Name:Foxo1Imported
Synonyms:Fkhr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1890077 Foxo1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ9WVH5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini157 – 251Fork-headInterPro annotationAdd BLAST95

Phylogenomic databases

eggNOGiKOG2294 Eukaryota
COG5025 LUCA
HOVERGENiHBG057789

Family and domain databases

CDDicd00059 FH, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR032067 FOXO-TAD
IPR032068 FOXO_KIX-bd
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PF16676 FOXO-TAD, 1 hit
PF16675 FOXO_KIX_bdg, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q9WVH5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEAPQVVET DPDFEPLPRQ RSCTWPLPRP EFNQSNSTTS SPAPSGGAAA
60 70 80 90 100
NPDAAASLAS ASAVSTDFMS NLSLLEESED FARAPGCVAV AAAAAASRGL
110 120 130 140 150
CGDFQGPEAG CVHPAPPQPP PTGPLSQPPP VPPSAAAAAG PLAGQPRKTS
160 170 180 190 200
SSRRNAWGNL SYADLITKAI ESSAEKRLTL SQIYEWMVKS VPYFKDKGDS
210 220 230 240 250
NSSAGWKNSI RHNLSLHSKF IRVQNEGTGK SSWWMLNPEG GKSGKSPRRR
260 270 280 290 300
AASMDNNSKF AKSRGRAAKK KASLQSGQEG PGDSPGSQFS KWPASPGSHS
310 320 330 340 350
NDDFDNWSTF RPRTSSNAST ISGRLSPIMT EQDDLGDGDV HSLVYPPSAA
360 370 380 390 400
KMASTLPSLS EISNPENMEN LLDNLNLLSS PTSLTVSTQS SPGSMMQQTP
410 420 430 440 450
CYSFAPPNTS LNSPSPNYSK YTYGQSSMSP LPQMPMQTLQ DSKSSYGGLN
460 470 480 490 500
QYNCAPGLLK ELLTSDSPPH NDIMSPVDPG VAQPNSRVLG QNVMMGPNSV
510 520 530 540 550
MPAYGSQASH NKMMNPSSHT HPGHAQQTAS VNGRTPPHVV NTMPHTSAMN
560 570 580 590 600
RLTPVKTPLQ VPLSHPMQMS ALGRYSSVSS CNGYGRMGVL HQEKLPSDLD
610 620 630 640 650
GMFIERLDCD MESIIRNDLM DGDTLDFNFD NVLPNQSFPH SVKTTTHSWV

SG
Length:652
Mass (Da):69,571
Last modified:November 1, 1999 - v1
Checksum:i5484409D93D0611B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF114258 mRNA Translation: AAD42106.1
UniGeneiMm.29891

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF114258 mRNA Translation: AAD42106.1
UniGeneiMm.29891

3D structure databases

ProteinModelPortaliQ9WVH5
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1890077 Foxo1

Phylogenomic databases

eggNOGiKOG2294 Eukaryota
COG5025 LUCA
HOVERGENiHBG057789

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

CDDicd00059 FH, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR032067 FOXO-TAD
IPR032068 FOXO_KIX-bd
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PF16676 FOXO-TAD, 1 hit
PF16675 FOXO_KIX_bdg, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ9WVH5_MOUSE
AccessioniPrimary (citable) accession number: Q9WVH5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: September 12, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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