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Protein

Macrophage-expressed gene 1 protein

Gene

Mpeg1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • defense response to bacterium Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Macrophage-expressed gene 1 protein
Short name:
Macrophage gene 1 protein
Short name:
Mpg-1
Gene namesi
Name:Mpeg1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi69275 Mpeg1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini20 – 653ExtracellularSequence analysisAdd BLAST634
Transmembranei654 – 674HelicalSequence analysisAdd BLAST21
Topological domaini675 – 714CytoplasmicSequence analysisAdd BLAST40

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000032414520 – 714Macrophage-expressed gene 1 proteinAdd BLAST695

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi185N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi269N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi375N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9WV57
PRIDEiQ9WV57

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000066960

Structurei

3D structure databases

ProteinModelPortaliQ9WV57
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 345MACPFPROSITE-ProRule annotationAdd BLAST316

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IER6 Eukaryota
ENOG410ZMVS LUCA
HOVERGENiHBG057416
InParanoidiQ9WV57
PhylomeDBiQ9WV57

Family and domain databases

InterProiView protein in InterPro
IPR020864 MACPF
IPR039707 MPEG1
PANTHERiPTHR31463 PTHR31463, 1 hit
PfamiView protein in Pfam
PF01823 MACPF, 1 hit
SMARTiView protein in SMART
SM00457 MACPF, 1 hit
PROSITEiView protein in PROSITE
PS51412 MACPF_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9WV57-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNSFMAIALI WMMIACAEAD KPLRDPGMTG FQTCKDTLKL PVLEVLPGGG
60 70 80 90 100
WDNLRNIDMG RVIDLTYTNC KTTEDGQYII PDEVYTIPQK ESNLEMNSEI
110 120 130 140 150
RDSWVNYQST TSFSINTELS LFSKVNGKFS TEFQRMKTLQ VKDQAVTTRV
160 170 180 190 200
QVRNRIYTVK NSPTSELSFG FTNALMDICD QLEKNQTKMA TYLAELLVLN
210 220 230 240 250
YGTHVITSVD AGAALVQEDH IRSSFLLDNQ NSENTVTASA GIAFLNIVNF
260 270 280 290 300
KVETDHTSQT LLTKSYLSNR TNSRVQSFGG IPFYPGITLE TWQKGITNHL
310 320 330 340 350
VAIDRAGLPL HFFIKPDKLP GLPGGLVKKL SKTVETAVRH YYTFNTHPGC
360 370 380 390 400
TNVDSPNFNF QANMEDDSCD AKVTNFTFGG LYQECTELSG DALCQNLEQK
410 420 430 440 450
NLLTGDFSCP SGYTPVHLLS QTHEEGYSRL ECKKKCTLKI FCKTVCEDVF
460 470 480 490 500
RVAKAQFRAY WCVATGQVPD NSGLLFGGLF TDKSINPMTN AQSCPAGYIP
510 520 530 540 550
LNLFESLKVC VSLDYELGYK FSVPFGGFFS CIMGNPLVNS DTAKDIGAPS
560 570 580 590 600
LKKCPGGFSQ HLAVISDGCQ VSYCVKAGIF TGGSLLPVRL PPYTKPPLMS
610 620 630 640 650
QVATNTVIVT SSETARSWIK DPQTNQWKLG EPLELHKAMT VIHGDGNGMS
660 670 680 690 700
GGEAAGVTLG VIIALGIVIT LAIYSTRKYK KEKEYQEIEE QESLVGSFAT
710
DASPPNGEQD PCPA
Length:714
Mass (Da):78,527
Last modified:March 18, 2008 - v2
Checksum:i3235512C40B9DF35
GO

Sequence cautioni

The sequence AAD38417 differs from that shown. Reason: Frameshift at several positions.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03005343 Genomic DNA No translation available.
AF156540 mRNA Translation: AAD38417.1 Frameshift.
UniGeneiRn.162497
Rn.4301

Genome annotation databases

UCSCiRGD:69275 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03005343 Genomic DNA No translation available.
AF156540 mRNA Translation: AAD38417.1 Frameshift.
UniGeneiRn.162497
Rn.4301

3D structure databases

ProteinModelPortaliQ9WV57
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000066960

Proteomic databases

PaxDbiQ9WV57
PRIDEiQ9WV57

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:69275 rat

Organism-specific databases

RGDi69275 Mpeg1

Phylogenomic databases

eggNOGiENOG410IER6 Eukaryota
ENOG410ZMVS LUCA
HOVERGENiHBG057416
InParanoidiQ9WV57
PhylomeDBiQ9WV57

Miscellaneous databases

PROiPR:Q9WV57

Family and domain databases

InterProiView protein in InterPro
IPR020864 MACPF
IPR039707 MPEG1
PANTHERiPTHR31463 PTHR31463, 1 hit
PfamiView protein in Pfam
PF01823 MACPF, 1 hit
SMARTiView protein in SMART
SM00457 MACPF, 1 hit
PROSITEiView protein in PROSITE
PS51412 MACPF_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMPEG1_RAT
AccessioniPrimary (citable) accession number: Q9WV57
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: November 7, 2018
This is version 58 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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