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Entry version 155 (23 Feb 2022)
Sequence version 2 (27 Jul 2011)
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Protein

Solute carrier family 2, facilitated glucose transporter member 5

Gene

Slc2a5

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:12031501, PubMed:19091748).

Can mediate the uptake of deoxyglucose, but with low efficiency (By similarity).

Essential for fructose uptake in the small intestine (PubMed:19091748, PubMed:26071406).

Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (PubMed:19091748).

Required for the development of high blood pressure in response to high dietary fructose intake (PubMed:19091748).

By similarity3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Fructose uptake is inhibited by cytochalasin B.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei31D-fructoseBy similarity1
Binding sitei166D-fructoseBy similarity1
Binding sitei287D-fructoseBy similarity1
Binding sitei386D-fructoseBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6798695, Neutrophil degranulation
R-MMU-8981373, Intestinal hexose absorption

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier family 2, facilitated glucose transporter member 5Curated
Alternative name(s):
Fructose transporterCurated
Glucose transporter type 5, small intestine1 Publication
Short name:
GLUT-51 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Slc2a5Imported
Synonyms:Glut51 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1928369, Slc2a5

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000028976

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 17CytoplasmicBy similarityAdd BLAST17
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei18 – 38Helical; Name=1By similarityAdd BLAST21
Topological domaini39 – 67ExtracellularBy similarityAdd BLAST29
Transmembranei68 – 90Helical; Name=2By similarityAdd BLAST23
Topological domaini91 – 97CytoplasmicBy similarity7
Transmembranei98 – 118Helical; Name=3By similarityAdd BLAST21
Topological domaini119 – 125ExtracellularBy similarity7
Transmembranei126 – 148Helical; Name=4By similarityAdd BLAST23
Topological domaini149 – 160CytoplasmicBy similarityAdd BLAST12
Transmembranei161 – 181Helical; Name=5By similarityAdd BLAST21
Topological domaini182 – 191ExtracellularBy similarity10
Transmembranei192 – 212Helical; Name=6By similarityAdd BLAST21
Topological domaini213 – 276CytoplasmicBy similarityAdd BLAST64
Transmembranei277 – 297Helical; Name=7By similarityAdd BLAST21
Topological domaini298 – 312ExtracellularBy similarityAdd BLAST15
Transmembranei313 – 333Helical; Name=8By similarityAdd BLAST21
Topological domaini334 – 341CytoplasmicBy similarity8
Transmembranei342 – 362Helical; Name=9By similarityAdd BLAST21
Topological domaini363 – 370ExtracellularBy similarity8
Transmembranei371 – 393Helical; Name=10By similarityAdd BLAST23
Topological domaini394 – 411CytoplasmicBy similarityAdd BLAST18
Transmembranei412 – 432Helical; Name=11By similarityAdd BLAST21
Topological domaini433 – 438ExtracellularBy similarity6
Transmembranei439 – 459Helical; Name=12By similarityAdd BLAST21
Topological domaini460 – 501CytoplasmicBy similarityAdd BLAST42

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice fed a standard diet appear normal and healthy, and display no visible phenotype (PubMed:18417103, PubMed:19091748, PubMed:26071406). Mutant mice show reduced food intake when kept on a high-frucose diet and about 28% reduction of their body weight within seven days. They loose more weight than wild-type mice that receive similar amounts of high-fructose food (PubMed:19091748). Mutant mice show strongly decreased fructose absorption in the jejunum (PubMed:19091748, PubMed:26071406). Contrary to wild-type, mutant mice have a strongly distended colon and caecum when kept on a high-fructose diet. Their intestines look normal when they are fed a standard diet. Contrary to wild-type, mutant mice do not display increased fructose levels in blood serum when kept on a high-fructose diet. Contrary to wild-type, they do not show increased salt absorption in response to fructose, and do not develop high blood pressure in response to fructose feeding. On the contrary, the blood pressure of mutant mice is strongly decreased after five days on a high-fructose diet. Mutant mice develop hypovolemic shock and die after 7 to 10 days on high-fructose diet (PubMed:19091748). Mutant mice display no defects of cochlear morphology or any hearing defects (PubMed:18417103).3 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000503701 – 501Solute carrier family 2, facilitated glucose transporter member 5Add BLAST501

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi50N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Acetylation, Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9WV38

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9WV38

PRoteomics IDEntifications database

More...
PRIDEi
Q9WV38

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
271187

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q9WV38, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9WV38

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9WV38

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected at the apical membrane of villi in the jejunum (PubMed:18496516, PubMed:19091748, PubMed:26071406). Detected in jejunum mucosa (PubMed:26071406). Detected in epididymis and whole testis (at protein level) (PubMed:18417103). Detected in small intestine, kidney and testis (PubMed:12031501, PubMed:18417103, PubMed:19091748). Detected in cochlea, but not in inner or outer cochlear hair cells (PubMed:18417103).4 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated in jejunum by dietary fructose intake (at protein level) (PubMed:18496516). Up-regulated in jejunum by dietary fructose intake (PubMed:18496516, PubMed:26071406). Up-regulated by dietary fructose intake in small intestine and testis (PubMed:12031501).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028976, Expressed in testis and 142 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9WV38, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
208011, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000030826

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9WV38, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9WV38

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni295 – 297D-fructose bindingBy similarity3
Regioni418 – 419D-fructose bindingBy similarity2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0569, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156846

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001265_30_5_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9WV38

Identification of Orthologs from Complete Genome Data

More...
OMAi
PTEMRGK

Database of Orthologous Groups

More...
OrthoDBi
326501at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9WV38

TreeFam database of animal gene trees

More...
TreeFami
TF313762

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1250.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002442, Fru_transpt_5
IPR045263, GLUT
IPR020846, MFS_dom
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR003663, Sugar/inositol_transpt
IPR005829, Sugar_transporter_CS

The PANTHER Classification System

More...
PANTHERi
PTHR23503, PTHR23503, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00083, Sugar_tr, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01194, GLUCTRSPORT5
PR00171, SUGRTRNSPORT

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473, SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00879, SP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850, MFS, 1 hit
PS00216, SUGAR_TRANSPORT_1, 1 hit
PS00217, SUGAR_TRANSPORT_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9WV38-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEKHQEETG ELTLVLALAT LIAAFGSSFQ YGYNVAAVNS PSEFMQQFYN
60 70 80 90 100
DTYYDRNEEN IESFTLTLLW SLTVSMFPFG GFIGSLMVGT LVNKLGRKGA
110 120 130 140 150
LLFNNIFSIL PAILMGCSQI AQSFELIIIS RLLVGICAGI SSNVVPMYLG
160 170 180 190 200
ELAPKNLRGA LGVVPQLFIT VGILVAQLFG LRSLLANEDG WPVLLGLTGV
210 220 230 240 250
PAGLQLLLLP FFPESPRYLL IQKKDEAAAE RALQTLRGWK DVHLEMEEIR
260 270 280 290 300
KEDEAEKAAG FISVWKLFTM QSLRWQLISM IVLMAGQQLS GVNAIYYYAD
310 320 330 340 350
QIYLSAGVKS DDVQYVTAGT GAVNVFMTIL TIFVVELWGR RFLLLVGFST
360 370 380 390 400
CLIACLVLTA ALALQNTISW MPYISIVCVI VYVIGHALGP SPIPALLITE
410 420 430 440 450
IFLQSSRPAA YMIGGSVHWL SNFTVGLIFP FIQMGLGPYS FIIFATICFL
460 470 480 490 500
TTIYIFMVVP ETKGRTFIEI NQIFTMKNKV SDVYPKKEEE LGALPHAILE

Q
Length:501
Mass (Da):55,409
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4F562A3BF848E5C7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti84G → S in AAD42235 (PubMed:12031501).Curated1
Sequence conflicti87M → V in AAD42235 (PubMed:12031501).Curated1
Sequence conflicti90T → N in AAD42235 (PubMed:12031501).Curated1
Sequence conflicti97 – 99RKG → KKR in AAD42235 (PubMed:12031501).Curated3
Sequence conflicti114L → F in AAD42235 (PubMed:12031501).Curated1
Sequence conflicti236L → I in AAD42235 (PubMed:12031501).Curated1
Sequence conflicti471N → I in AAD42235 (PubMed:12031501).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF161071 mRNA Translation: AAD42235.1
AK029720 mRNA Translation: BAC26582.1
AL606971 Genomic DNA No translation available.
CU210939 Genomic DNA No translation available.
CH466594 Genomic DNA Translation: EDL14883.1
BC023500 mRNA Translation: AAH23500.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18968.1

NCBI Reference Sequences

More...
RefSeqi
NP_062715.2, NM_019741.3
XP_006539139.1, XM_006539076.3
XP_017175818.1, XM_017320329.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000030826; ENSMUSP00000030826; ENSMUSG00000028976

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
56485

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:56485

UCSC genome browser

More...
UCSCi
uc008vxk.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF161071 mRNA Translation: AAD42235.1
AK029720 mRNA Translation: BAC26582.1
AL606971 Genomic DNA No translation available.
CU210939 Genomic DNA No translation available.
CH466594 Genomic DNA Translation: EDL14883.1
BC023500 mRNA Translation: AAH23500.1
CCDSiCCDS18968.1
RefSeqiNP_062715.2, NM_019741.3
XP_006539139.1, XM_006539076.3
XP_017175818.1, XM_017320329.1

3D structure databases

SMRiQ9WV38
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi208011, 1 interactor
STRINGi10090.ENSMUSP00000030826

PTM databases

GlyGeniQ9WV38, 1 site
iPTMnetiQ9WV38
PhosphoSitePlusiQ9WV38

Proteomic databases

jPOSTiQ9WV38
PaxDbiQ9WV38
PRIDEiQ9WV38
ProteomicsDBi271187

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1404, 419 antibodies from 33 providers

The DNASU plasmid repository

More...
DNASUi
56485

Genome annotation databases

EnsembliENSMUST00000030826; ENSMUSP00000030826; ENSMUSG00000028976
GeneIDi56485
KEGGimmu:56485
UCSCiuc008vxk.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6518
MGIiMGI:1928369, Slc2a5
VEuPathDBiHostDB:ENSMUSG00000028976

Phylogenomic databases

eggNOGiKOG0569, Eukaryota
GeneTreeiENSGT00940000156846
HOGENOMiCLU_001265_30_5_1
InParanoidiQ9WV38
OMAiPTEMRGK
OrthoDBi326501at2759
PhylomeDBiQ9WV38
TreeFamiTF313762

Enzyme and pathway databases

ReactomeiR-MMU-6798695, Neutrophil degranulation
R-MMU-8981373, Intestinal hexose absorption

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
56485, 1 hit in 63 CRISPR screens

Protein Ontology

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PROi
PR:Q9WV38
RNActiQ9WV38, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000028976, Expressed in testis and 142 other tissues
GenevisibleiQ9WV38, MM

Family and domain databases

Gene3Di1.20.1250.20, 1 hit
InterProiView protein in InterPro
IPR002442, Fru_transpt_5
IPR045263, GLUT
IPR020846, MFS_dom
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR003663, Sugar/inositol_transpt
IPR005829, Sugar_transporter_CS
PANTHERiPTHR23503, PTHR23503, 1 hit
PfamiView protein in Pfam
PF00083, Sugar_tr, 1 hit
PRINTSiPR01194, GLUCTRSPORT5
PR00171, SUGRTRNSPORT
SUPFAMiSSF103473, SSF103473, 1 hit
TIGRFAMsiTIGR00879, SP, 1 hit
PROSITEiView protein in PROSITE
PS50850, MFS, 1 hit
PS00216, SUGAR_TRANSPORT_1, 1 hit
PS00217, SUGAR_TRANSPORT_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGTR5_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9WV38
Secondary accession number(s): Q8R1N7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: July 27, 2011
Last modified: February 23, 2022
This is version 155 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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