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Entry version 96 (29 Sep 2021)
Sequence version 1 (01 Nov 1999)
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Protein
Submitted name:

Hyaluronan receptor RHAMM

Gene

Hmmr

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptorImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Hyaluronan receptor RHAMMImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HmmrImported
Synonyms:RhammImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

Rat genome database

More...
RGDi
2805, Hmmr

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini15 – 338HMMR_NInterPro annotationAdd BLAST324
Domaini552 – 708HMMR_CInterPro annotationAdd BLAST157

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 59DisorderedSequence analysisAdd BLAST59

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili99 – 119Sequence analysisAdd BLAST21
Coiled coili134 – 154Sequence analysisAdd BLAST21
Coiled coili157 – 177Sequence analysisAdd BLAST21
Coiled coili210 – 230Sequence analysisAdd BLAST21
Coiled coili241 – 275Sequence analysisAdd BLAST35
Coiled coili286 – 338Sequence analysisAdd BLAST53
Coiled coili371 – 422Sequence analysisAdd BLAST52
Coiled coili463 – 504Sequence analysisAdd BLAST42
Coiled coili530 – 561Sequence analysisAdd BLAST32
Coiled coili597 – 617Sequence analysisAdd BLAST21
Coiled coili634 – 668Sequence analysisAdd BLAST35

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi25 – 59Polar residuesSequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
EHGATQE

Database of Orthologous Groups

More...
OrthoDBi
604725at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9WUF7

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031794, HMMR_C
IPR031787, HMMR_N
IPR026203, IHABP

The PANTHER Classification System

More...
PANTHERi
PTHR18956, PTHR18956, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15908, HMMR_C, 1 hit
PF15905, HMMR_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9WUF7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSFPKAPLKR FNDPSGCAPS PGAYDVKTSE STKGPVSFQK SQRFKNQRES
60 70 80 90 100
QQNLNIDKDT TLLASAKKAK TLVSKKESQK NDKDVKRLEK EIHVLLQERG
110 120 130 140 150
TQDKRIQDME SELENTEANL NAPVTEKPSL SANNASLEKR LTELTRANEL
160 170 180 190 200
LKSKFSEDAH QKNMRTLSLE LMKLRNKRET KMRSMMAKQE GMELKLQATQ
210 220 230 240 250
KDLIESKGKI VQLEGKLVSI EKEKIDEKSE TEKLLEYIEE ISCASDQVEK
260 270 280 290 300
YKLDIAQLEE DLKEKDREIL CLKQSLEEKV SFSKQIEDLT VKCQLLEAER
310 320 330 340 350
DDLVSKDRER AESLSAEMQV LTEKLLLERQ EYEKLQQNEL QSQSLLQQEK
360 370 380 390 400
ELSAHLQQQL CSFQEEMTSE RNVFKEQLKL ALDELDAVQQ KKEQSEKLVK
410 420 430 440 450
QLEEETKSTA EQLRRLDDLL REKEIELEKR TAAHAQATVI AQEKYSDTAQ
460 470 480 490 500
TLRDVTAQLE SYKSSTLKEI EDLKLENLTL QEKVAMAEKR VEDVQQQILT
510 520 530 540 550
AESTNQEYAK VVQDLQNSST LKEAEIKEIT SSYLEKITDL QNQLRQQNED
560 570 580 590 600
FRKQLEEEGA KMTEKETAVT ELTMEINKWR LLYEELFDKT KPFQQQLDAF
610 620 630 640 650
EAEKQALLNE HGATQEQLSK IRDSYAQLLG HQNLKQKIKH VVKLKDENSQ
660 670 680 690 700
LKSEVSKLRS QLAKRKQNEL RLQGELDKAL GIRHFDPSKA FCHESKENVT
710
LKTPLKEGNP NCC
Length:713
Mass (Da):82,395
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2FE310D5759C6CB3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF133037 mRNA Translation: AAD24473.1
AF336825 mRNA Translation: AAK21904.1

NCBI Reference Sequences

More...
RefSeqi
NP_037096.2, NM_012964.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
25460

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:25460

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF133037 mRNA Translation: AAD24473.1
AF336825 mRNA Translation: AAK21904.1
RefSeqiNP_037096.2, NM_012964.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi25460
KEGGirno:25460

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3161
RGDi2805, Hmmr

Phylogenomic databases

OMAiEHGATQE
OrthoDBi604725at2759
PhylomeDBiQ9WUF7

Family and domain databases

InterProiView protein in InterPro
IPR031794, HMMR_C
IPR031787, HMMR_N
IPR026203, IHABP
PANTHERiPTHR18956, PTHR18956, 2 hits
PfamiView protein in Pfam
PF15908, HMMR_C, 1 hit
PF15905, HMMR_N, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9WUF7_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9WUF7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: September 29, 2021
This is version 96 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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