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Entry version 124 (08 May 2019)
Sequence version 2 (27 Jul 2011)
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Protein

CASP8-associated protein 2

Gene

Casp8ap2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation (By similarity). Required for histone gene transcription and progression through S phase (By similarity). Required for histone gene transcription and S phase progression (By similarity). Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis.By similarity2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Repressor
Biological processApoptosis, Cell cycle, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-3899300 SUMOylation of transcription cofactors

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CASP8-associated protein 2
Alternative name(s):
FLICE-associated huge protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Casp8ap2Imported
Synonyms:FlashImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1349399 Casp8ap2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Mitochondrion, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000761892 – 1962CASP8-associated protein 2Add BLAST1961

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei20PhosphoserineBy similarity1
Modified residuei560PhosphoserineBy similarity1
Modified residuei798PhosphoserineBy similarity1
Modified residuei858PhosphoserineBy similarity1
Modified residuei923PhosphoserineBy similarity1
Modified residuei1323N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9WUF3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9WUF3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9WUF3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9WUF3

PeptideAtlas

More...
PeptideAtlasi
Q9WUF3

PRoteomics IDEntifications database

More...
PRIDEi
Q9WUF3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9WUF3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9WUF3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in heart, brain, thymus, lung, testis and spleen.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028282 Expressed in 289 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9WUF3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9WUF3 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Self-associates.

Interacts with NPAT (By similarity).

Interacts with SRRT (By similarity).

Interacts (via SIM domains) with SUMO1 and SUMO2 (By similarity).

Interacts with SP100; may negatively regulate CASP8AP2 export from the nucleus to the cytoplasm (By similarity).

Interacts with NCOA2 and NCOA3 (By similarity).

Component of the death-inducing signaling complex (DISC) with CASP8, FADD and FAS.

Interacts with TRAF2.

By similarity3 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
205038, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q9WUF3, 3 interactors

Molecular INTeraction database

More...
MINTi
Q9WUF3

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000029950

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9WUF3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1688 – 1962NCOA2-bindingBy similarityAdd BLAST275

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1716 – 1720SUMO interaction motif 1 (SIM); mediates the binding to polysumoylated substratesBy similarity5

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEBH Eukaryota
ENOG410YRSQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00620000088063

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000049238

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9WUF3

Identification of Orthologs from Complete Genome Data

More...
OMAi
FCDSINF

Database of Orthologous Groups

More...
OrthoDBi
31356at2759

TreeFam database of animal gene trees

More...
TreeFami
TF332487

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039674 FLASH

The PANTHER Classification System

More...
PANTHERi
PTHR15489 PTHR15489, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9WUF3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAADDDNGDG TGLFDVCPAS PLKNNDEGSL DIYAGLDSAV SDSTARSCVS
60 70 80 90 100
FRNCLDLYEE ILTEEGTAKE ATYNDLQIEY GKCQQQMKDL MKRFKEIQTQ
110 120 130 140 150
NLNLKNENQS LKKNISALIK TARVEINRKD EEINHLHQRL SEFPHFRNNH
160 170 180 190 200
KTARTKDSQS TSPHLDDCSK TDHGVKSDVQ KDVHPNTAQP NLEKEGKSHS
210 220 230 240 250
EAQNPLHLST GVEKHCANNV WSRSPYQVGE GNSNEDNRRG RSGTRHSQCS
260 270 280 290 300
RGTDRTQKDL HSSCNDSEPR DKEANSRLQG HPEKHGNSEA RTESKISESK
310 320 330 340 350
SSTGMGYKSE RSASSWEKET SRERPHTRVE SQHDKNLEKQ NERLQNMHRK
360 370 380 390 400
ELPSQDKTER KVDVKFKPAG EEQGHRGRVD RALPPHPKND VKHYGFNKYH
410 420 430 440 450
PEERRGREDC KRDRGMNSHG FQDRRCSSFL SSNRNSKYPH SKEVSVAHQW
460 470 480 490 500
ENTPFKAERH RTEDRRKRER ENKEESRHVK SDKKSPPEHL QRTHKDTKKS
510 520 530 540 550
TADGKRQTEP KHGKGAVSNS ELSKGTDSKE GATKVESGPN EAKGKDLKLS
560 570 580 590 600
FMEKLNLTLS PAKKQPACQD NPHQITGVPE PSGTCDSRSL ETTGTVACLP
610 620 630 640 650
SGSEHNREET KSELPEPKEA LLATSQLRIS IPENKMKEEK RLLFKSVENT
660 670 680 690 700
VPCELLACGT EISLPAPVEI EQARCLLGSV EVEETCGGAR TAASVVMHVL
710 720 730 740 750
PEHASEDASQ ELDTKRHDGI NACAISEGVK TKVILSPKAA AASESHLAPL
760 770 780 790 800
VEEPSISLVN CSGDNNPKLE PSLEERPIVE TKSCPLESCL PKETFVPSPQ
810 820 830 840 850
KTELIDHKIE TGESNSVYQD DDNSVLSIDF NNLRPIPDPI SPLNSPVRPV
860 870 880 890 900
CKVVSMESSC AIPLYDSSHK DEFPSNSTLS TFKSQSDLNK ENEKPVPKFD
910 920 930 940 950
KCSEADSCKH LSLDELEEGE IRSDDEESVA QKRLEKSARP RVSAEVQPGK
960 970 980 990 1000
SSPGSRRSTV HVHKDNGRTA VKLPRDRLTW SKRSSESRPS NTERKSKTMS
1010 1020 1030 1040 1050
ISSLEKILPL ILVPSSLWEV MHMLRLLGKH VRKNYMKFKI KFSLTQFHRI
1060 1070 1080 1090 1100
IESAILSFTS LVKCLDLSKI CKSVSTLQKS LCEVIESNLK QVKKNGIVDR
1110 1120 1130 1140 1150
LFEQQQTDMK KKLWKFVDEQ LDYLFEKLKK ILLKFCDSVN FENENSEGKL
1160 1170 1180 1190 1200
GKKYKERTQH SNCQKKKMDN KEIRREKVLK SENTVNFKSS LGCEKSEEKH
1210 1220 1230 1240 1250
QDQNKTNASI VKHDVKRTFS TCSDNTKNAE CKEQFLEKSC PSTPRPGKDE
1260 1270 1280 1290 1300
GHTEEEAQAA QHASAKSERS FEILTEQQAS SLTFNLVSDA QMGEIFKSLL
1310 1320 1330 1340 1350
QGSDLLDTSG TEKAEWELKT PEKQLLESLK CESAPACATE ELVSEGASLC
1360 1370 1380 1390 1400
PKVISDDNWS LLSSEKGPSL SSGLSLPVHP DVLDENCMFE VSSNTALGKD
1410 1420 1430 1440 1450
NVYSSEKSKP CISSILLEDL AVSLTVPSPL KSDGHLSFLK PEVLSTSTPE
1460 1470 1480 1490 1500
EVISAHFSED ALLEEEDASE QDIHLALESD NSSSKSSCSS WTSRSVASGF
1510 1520 1530 1540 1550
QYHPNLPMHA VIMEKSNDHF IVKIRRATPS TSPGLKHGVV AEESLTSLPR
1560 1570 1580 1590 1600
TGKEAGVATE KEPNLFQSTV LKPVKDLENT DKNIDKSKLT HEEQNSIVQT
1610 1620 1630 1640 1650
QVPDIYEFLK DASNKVVHCD QVVDDCFKLH QVWEPKVSEN LQELPSMEKI
1660 1670 1680 1690 1700
PHSLDNHLPD THIDLTKDSA TETKSLGELM EVTVLNVDHL ECSQTNLDQD
1710 1720 1730 1740 1750
AEITCSSLQP DTIDAFIDLT HDASSESKNE GSEPVLAVEG MGCQVICIDE
1760 1770 1780 1790 1800
DTNKEGKMGR ANSPLESIVE ETCIDLTSES PGSCEIKRHN LKSEPPSKLD
1810 1820 1830 1840 1850
CLELPETLGN GHKKRKNSPG VSHSSQKKQR KDIDLSSEKT QRLSPNSDRN
1860 1870 1880 1890 1900
GDAHRKQASK KREPAVNETS LSSEASPEVK GSTAVLAASP ASLSAKNVIK
1910 1920 1930 1940 1950
KKGEIIVSWT RNDDREILLE CQKRMPSLKT FTYLAVKLNK NPNQVSERFQ
1960
QLKKLFEKSK CR
Length:1,962
Mass (Da):219,091
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7B3FC637BB98D9EF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AX75B1AX75_MOUSE
CASP8-associated protein 2
Casp8ap2
190Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti152T → A in AAD29045 (PubMed:10235259).Curated1
Sequence conflicti1062V → I in AAD29045 (PubMed:10235259).Curated1
Sequence conflicti1766E → K in BAB27860 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF132726 mRNA Translation: AAD29045.1
AL805973 Genomic DNA No translation available.
BC138022 mRNA Translation: AAI38023.1
BC138041 mRNA Translation: AAI38042.1
AK011818 mRNA Translation: BAB27860.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18016.1

NCBI Reference Sequences

More...
RefSeqi
NP_001116450.1, NM_001122978.2
NP_036127.2, NM_011997.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000029950; ENSMUSP00000029950; ENSMUSG00000028282
ENSMUST00000178925; ENSMUSP00000136016; ENSMUSG00000028282

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
26885

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:26885

UCSC genome browser

More...
UCSCi
uc008sew.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF132726 mRNA Translation: AAD29045.1
AL805973 Genomic DNA No translation available.
BC138022 mRNA Translation: AAI38023.1
BC138041 mRNA Translation: AAI38042.1
AK011818 mRNA Translation: BAB27860.1
CCDSiCCDS18016.1
RefSeqiNP_001116450.1, NM_001122978.2
NP_036127.2, NM_011997.3

3D structure databases

SMRiQ9WUF3
ModBaseiSearch...

Protein-protein interaction databases

BioGridi205038, 1 interactor
IntActiQ9WUF3, 3 interactors
MINTiQ9WUF3
STRINGi10090.ENSMUSP00000029950

PTM databases

iPTMnetiQ9WUF3
PhosphoSitePlusiQ9WUF3

Proteomic databases

EPDiQ9WUF3
jPOSTiQ9WUF3
MaxQBiQ9WUF3
PaxDbiQ9WUF3
PeptideAtlasiQ9WUF3
PRIDEiQ9WUF3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000029950; ENSMUSP00000029950; ENSMUSG00000028282
ENSMUST00000178925; ENSMUSP00000136016; ENSMUSG00000028282
GeneIDi26885
KEGGimmu:26885
UCSCiuc008sew.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9994
MGIiMGI:1349399 Casp8ap2

Phylogenomic databases

eggNOGiENOG410IEBH Eukaryota
ENOG410YRSQ LUCA
GeneTreeiENSGT00620000088063
HOGENOMiHOG000049238
InParanoidiQ9WUF3
OMAiFCDSINF
OrthoDBi31356at2759
TreeFamiTF332487

Enzyme and pathway databases

ReactomeiR-MMU-3899300 SUMOylation of transcription cofactors

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Casp8ap2 mouse

Protein Ontology

More...
PROi
PR:Q9WUF3

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000028282 Expressed in 289 organ(s), highest expression level in embryo
ExpressionAtlasiQ9WUF3 baseline and differential
GenevisibleiQ9WUF3 MM

Family and domain databases

InterProiView protein in InterPro
IPR039674 FLASH
PANTHERiPTHR15489 PTHR15489, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC8AP2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9WUF3
Secondary accession number(s): B1AX74, Q9CSW2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 27, 2011
Last modified: May 8, 2019
This is version 124 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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