Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 133 (29 Sep 2021)
Sequence version 1 (01 Nov 1999)
Previous versions | rss
Add a publicationFeedback
Protein

Teneurin-3

Gene

Tenm3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in neural development by regulating the establishment of proper connectivity within the nervous system (PubMed:17478416, PubMed:17803360, PubMed:23028443, PubMed:25406022, PubMed:22499796, PubMed:29414938).

Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion (PubMed:29414938).

Promotes homophilic adhesion in a splicing isoform-dependent manner: most isoforms (isoform-type A and type-B) can mediate homophilic interaction (PubMed:29414938).

Promotes axon guidance (PubMed:23028443).

Required for proper dendrite morphogenesis and axon targeting in the vertebrate visual system, thereby playing a key role in the development of the visual pathway (PubMed:17803360, PubMed:23028443, PubMed:25406022, PubMed:22499796).

Regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC) (PubMed:17803360, PubMed:23028443).

May also be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes (PubMed:20636325).

7 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion, Differentiation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Teneurin-31 Publication
Short name:
Ten-31 Publication
Alternative name(s):
Protein Odd Oz/ten-m homolog 32 Publications
Tenascin-M31 Publication
Short name:
Ten-m31 Publication
Teneurin transmembrane protein 31 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tenm3Imported
Synonyms:Kiaa14551 Publication, Odz32 Publications, Tnm31 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1345183, Tenm3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 310CytoplasmicSequence analysisAdd BLAST310
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei311 – 331HelicalSequence analysisAdd BLAST21
Topological domaini332 – 2715ExtracellularSequence analysisAdd BLAST2384

Keywords - Cellular componenti

Cell membrane, Cell projection, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice show impair binocular vision, consistent with altered ipsilateral retinal neuron projections both into the ventrolateral region of the lateral geniculate nucleus (dLGN) and the superior colliculus (SC) (PubMed:17803360, PubMed:23028443). The distribution of ipsilateral drive in V1 is altered, leading to an expanded but visuotopically misaligned binocular zone (PubMed:22499796). Conditional knockout mice lacking Tenm3 in CA1 neurons display proximal CA1 axons spread throughout the entire subiculum, instead of projecting only to distal regions (PubMed:29414938). When Tenm3 is absent from a subset of distal subicular cells, Tenm3-containing proximal CA1 axons do not target Tenm3 and instead innervate nearby Tenm3 regions (PubMed:29414938).4 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002595061 – 2715Teneurin-3Add BLAST2715

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi345N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi380N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi419N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi518 ↔ 528PROSITE-ProRule annotation
Disulfide bondi522 ↔ 533PROSITE-ProRule annotation
Disulfide bondi535 ↔ 544PROSITE-ProRule annotation
Disulfide bondi553 ↔ 564PROSITE-ProRule annotation
Disulfide bondi566 ↔ 575PROSITE-ProRule annotation
Disulfide bondi582 ↔ 593PROSITE-ProRule annotation
Disulfide bondi587 ↔ 598PROSITE-ProRule annotation
Disulfide bondi600 ↔ 609PROSITE-ProRule annotation
Disulfide bondi614 ↔ 625PROSITE-ProRule annotation
Disulfide bondi619 ↔ 630PROSITE-ProRule annotation
Disulfide bondi632 ↔ 641PROSITE-ProRule annotation
Disulfide bondi652 ↔ 665PROSITE-ProRule annotation
Disulfide bondi667 ↔ 676PROSITE-ProRule annotation
Glycosylationi670N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi681 ↔ 691PROSITE-ProRule annotation
Disulfide bondi685 ↔ 696PROSITE-ProRule annotation
Disulfide bondi698 ↔ 707PROSITE-ProRule annotation
Disulfide bondi712 ↔ 722PROSITE-ProRule annotation
Disulfide bondi716 ↔ 727PROSITE-ProRule annotation
Disulfide bondi729 ↔ 738PROSITE-ProRule annotation
Disulfide bondi752 ↔ 762PROSITE-ProRule annotation
Disulfide bondi756 ↔ 771PROSITE-ProRule annotation
Disulfide bondi773 ↔ 782PROSITE-ProRule annotation
Glycosylationi869N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi892N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1211N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1543N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1560N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1656N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1693N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1751N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1836N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1937N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2140N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi2280N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2592N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9WTS6

PRoteomics IDEntifications database

More...
PRIDEi
Q9WTS6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
258991 [Q9WTS6-1]
258992 [Q9WTS6-2]

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2431, 3 N-Linked glycans (2 sites) [Q9WTS6-2]
2757, 4 N-Linked glycans (2 sites)

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q9WTS6, 17 sites, 4 N-linked glycans (2 sites)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9WTS6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9WTS6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In brain, expressed in highly specific regions of the postnatal brain: expressed in restricted domains of the developing hippocampal region, including proximal CA1, distal subiculum, and medial entorhinal cortex (at protein level) (PubMed:29414938). Expression matches with topographic connectivity between entorhinal cortex, CA1, and subiculum (at protein level) (PubMed:29414938). Also specifically expressed in subregions of the presubiculum, parasubiculum, medial mammillary nucleus and anteroventral thalamic nucleus that are topographically connected with subiculum or entorhinal cortex (at protein level) (PubMed:29414938). Expressed in neurons of the developing visual pathway (at protein level). Expressed in the dorsal and ventral lateral geniculate nucleus (dLGN and vLGN) and optic tract at birth. Expressed in ipsilateral retinal axons of terminal zones (TZs) in the developing superior colliculus (SC) throughout the first postnatal week. Expressed in the layer V of the visual caudal cortex. Expressed in the femoral and mandibular condylar cartilages. Strongly expressed in fibrous and proliferating chondrocytes. Poorly expressed in mature chondrocytes. Not expressed in hypertrophic chondrocytes (PubMed:12915301, PubMed:17478416, PubMed:17803360, PubMed:20636325, PubMed:23028443).6 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in the neural plate at 7.5 dpc. Expressed in the forebrain and telencephalon at 8.5 dpc. Expressed in the diencephalon, spinal cord and midbrain at 12.5 dpc. Expressed in the retinal ganglion cell (RGC) layer and the dorsal lateral geniculate nucleus (dLGN) at 16 dpc. Expressed in ipsilateral retinal axons of terminal zones (TZs) in the developing superior colliculus (SC) at 16 dpc, onward.3 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer; disulfide-linked; to mediate homophilic cell adhesion (PubMed:29414938, PubMed:12000766). Most isoforms (isoform-type A and type-B) can mediate homophilic interaction (PubMed:29414938). Heterodimer with either TENM1 or TENM2 (PubMed:12000766). May also form heterodimer with TENM4 (PubMed:12000766). Isoform A0B0: Does not form homodimer to mediate homophilic cell adhesion. Isoform A0B0: Heterodimer with ADGRL3 (PubMed:29414938).

2 Publications

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9WTS6, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000140141

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9WTS6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9WTS6

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 309Teneurin N-terminalPROSITE-ProRule annotationAdd BLAST309
Domaini514 – 545EGF-like 1PROSITE-ProRule annotationAdd BLAST32
Domaini546 – 576EGF-like 2PROSITE-ProRule annotationAdd BLAST31
Domaini578 – 610EGF-like 3PROSITE-ProRule annotationAdd BLAST33
Domaini611 – 642EGF-like 4PROSITE-ProRule annotationAdd BLAST32
Domaini644 – 677EGF-like 5PROSITE-ProRule annotationAdd BLAST34
Domaini678 – 709EGF-like 6PROSITE-ProRule annotationAdd BLAST32
Domaini710 – 739EGF-like 7PROSITE-ProRule annotationAdd BLAST30
Domaini740 – 783EGF-like 8PROSITE-ProRule annotationAdd BLAST44
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1181 – 1209NHL 1Add BLAST29
Repeati1216 – 1260NHL 2Add BLAST45
Repeati1286 – 1330NHL 3Add BLAST45
Repeati1347 – 1387NHL 4Add BLAST41
Repeati1418 – 1445NHL 5Add BLAST28
Repeati1474 – 1517NHL 6Add BLAST44
Repeati1527 – 1546YD 1Add BLAST20
Repeati1563 – 1583YD 2Add BLAST21
Repeati1626 – 1645YD 3Add BLAST20
Repeati1646 – 1668YD 4Add BLAST23
Repeati1839 – 1858YD 5Add BLAST20
Repeati1880 – 1898YD 6Add BLAST19
Repeati1899 – 1919YD 7Add BLAST21
Repeati1926 – 1943YD 8Add BLAST18
Repeati1944 – 1965YD 9Add BLAST22
Repeati1966 – 1983YD 10Add BLAST18
Repeati1986 – 2006YD 11Add BLAST21
Repeati2009 – 2029YD 12Add BLAST21
Repeati2037 – 2056YD 13Add BLAST20
Repeati2062 – 2079YD 14Add BLAST18
Repeati2080 – 2106YD 15Add BLAST27
Repeati2108 – 2121YD 16Add BLAST14
Repeati2122 – 2145YD 17Add BLAST24
Repeati2148 – 2168YD 18Add BLAST21
Repeati2169 – 2189YD 19Add BLAST21
Repeati2191 – 2211YD 20Add BLAST21
Repeati2223 – 2243YD 21Add BLAST21
Repeati2245 – 2265YD 22Add BLAST21
Repeati2291 – 2332YD 23Add BLAST42

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 38DisorderedSequence analysisAdd BLAST38
Regioni142 – 223DisorderedSequence analysisAdd BLAST82

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 28Basic and acidic residuesSequence analysisAdd BLAST28
Compositional biasi142 – 159Polar residuesSequence analysisAdd BLAST18
Compositional biasi194 – 216Polar residuesSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

EGF-like domains 2 and 5 which have an odd number of cysteines might enable the formation of intermolecular disulfide bonds.1 Publication
Cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteins.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tenascin family. Teneurin subfamily.Curated

Keywords - Domaini

EGF-like domain, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4659, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9WTS6

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9WTS6

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.120.10.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011042, 6-blade_b-propeller_TolB-like
IPR008969, CarboxyPept-like_regulatory
IPR000742, EGF-like_dom
IPR022385, Rhs_assc_core
IPR027691, Ten-3/4
IPR009471, Ten_N
IPR028916, Tox-GHH_dom
IPR006530, YD

The PANTHER Classification System

More...
PANTHERi
PTHR11219:SF65, PTHR11219:SF65, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06484, Ten_N, 2 hits
PF15636, Tox-GHH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 8 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49464, SSF49464, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022, EGF_1, 8 hits
PS01186, EGF_2, 7 hits
PS50026, EGF_3, 5 hits
PS51361, TENEURIN_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (8+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 8 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: 8 different isoforms are produced by the inclusion or exclusion of 'exon 12' and 'exon 20' (at splice sites A and B, respectively). The different isoforms probably mediate a combination of specific homophilic and/or heterophilic interactions.1 Publication

This entry has 8 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform A1B11 Publication (identifier: Q9WTS6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDVKERRPYC SLTKSRREKE RRYTNSSADN EECRVPTQKS YSSSETLKAF
60 70 80 90 100
DHDYSRLLYG NRVKDLVHRE ADEYTRQGQN FTLRQLGVCE SATRRGVAFC
110 120 130 140 150
AEMGLPHRGY SISAGSDADT ENEAVMSPEH AMRLWGRGVK SGRSSCLSSR
160 170 180 190 200
SNSALTLTDT EHENRSDSES EQPSNNPGQP TLQPLPPSHK QHPAQHHPSI
210 220 230 240 250
TSLNRNSLTN RRNQSPAPPA ALPAELQTTP ESVQLQDSWV LGSNVPLESR
260 270 280 290 300
HFLFKTGTGT TPLFSTATPG YTMASGSVYS PPTRPLPRNT LSRSAFKFKK
310 320 330 340 350
SSKYCSWRCT ALCAVGVSVL LAILLSYFIA MHLFGLNWHL QQTENDTFEN
360 370 380 390 400
GKVNSDTVPT NTVSLPSGDN GKLGGFTHEN NTIDSGELDI GRRAIQEVPP
410 420 430 440 450
GIFWRSQLFI DQPQFLKFNI SLQKDALIGV YGRKGLPPSH TQYDFVELLD
460 470 480 490 500
GSRLIAREQR NLVESERAGR QARSVSLHEA GFIQYLDSGI WHLAFYNDGK
510 520 530 540 550
NPEQVSFNTI VIESVVECPR NCHGNGECVS GTCHCFPGFL GPDCSRAACP
560 570 580 590 600
VLCSGNGQYS KGRCLCFSGW KGTECDVPTT QCIDPQCGGR GICIMGSCAC
610 620 630 640 650
NSGYKGENCE EADCLDPGCS NHGVCIHGEC HCNPGWGGSN CEILKTMCAD
660 670 680 690 700
QCSGHGTYLQ ESGSCTCDPN WTGPDCSNEI CSVDCGSHGV CMGGSCRCEE
710 720 730 740 750
GWTGPACNQR ACHPRCAEHG TCKDGKCECS QGWNGEHCTI AHYLDKIVKE
760 770 780 790 800
GCPGLCNSNG RCTLDQNGWH CVCQPGWRGA GCDVAMETLC TDSKDNEGDG
810 820 830 840 850
LIDCMDPDCC LQSSCQNQPY CRGLPDPQDI ISQSLQTPSQ QAAKSFYDRI
860 870 880 890 900
SFLIGSDSTH VLPGESPFNK SLASVIRGQV LTADGTPLIG VNVSFLHYSE
910 920 930 940 950
YGYTITRQDG MFDLVANGGA SLTLVFERSP FLTQYHTVWI PWNVFYVMDT
960 970 980 990 1000
LVMKKEENDI PSCDLSGFVR PSPIIVSSPL STFFRSSPED SPIIPETQVL
1010 1020 1030 1040 1050
HEETTIPGTD LKLSYLSSRA AGYKSVLKIT MTQAVIPFNL MKVHLMVAVV
1060 1070 1080 1090 1100
GRLFQKWFPA SPNLAYTFIW DKTDAYNQKV YGLSEAVVSV GYEYESCLDL
1110 1120 1130 1140 1150
TLWEKRTAVL QGYELDASNM GGWTLDKHHV LDVQNGILYK GNGENQFISQ
1160 1170 1180 1190 1200
QPPVVSSIMG NGRRRSISCP SCNGQADGNK LLAPVALACG IDGSLYVGDF
1210 1220 1230 1240 1250
NYVRRIFPSG NVTSVLELRN KDFRHSSNPA HRYYLATDPV TGDLYVSDTN
1260 1270 1280 1290 1300
TRRIYRPKSL TGAKDLTKNA EVVAGTGEQC LPFDEARCGD GGKAVEATLM
1310 1320 1330 1340 1350
SPKGMAIDKN GLIYFVDGTM IRKVDQNGII STLLGSNDLT SARPLTCDTS
1360 1370 1380 1390 1400
MHISQVRLEW PTDLAINPMD NSIYVLDNNV VLQITENRQV RIAAGRPMHC
1410 1420 1430 1440 1450
QVPGVEYPVG KHAVQTTLES ATAIAVSYSG VLYITETDEK KINRIRQVTT
1460 1470 1480 1490 1500
DGEISLVAGI PSECDCKNDA NCDCYQSGDG YAKDAKLNAP SSLAASPDGT
1510 1520 1530 1540 1550
LYIADLGNIR IRAVSKNKPL LNSMNFYEVA SPTDQELYIF DINGTHQYTV
1560 1570 1580 1590 1600
SLVTGDYLYN FSYSNDNDVT AVTDSNGNTL RIRRDPNRMP VRVVSPDNQV
1610 1620 1630 1640 1650
IWLTIGTNGC LKSMTAQGLE LVLFTYHGNS GLLATKSDET GWTTFFDYDS
1660 1670 1680 1690 1700
EGRLTNVTFP TGVVTNLHGD MDKAITVDIE SSSREEDVSI TSNLSSIDSF
1710 1720 1730 1740 1750
YTMVQDQLRN SYQIGYDGSL RIFYASGLDS HYQTEPHVLA GTANPTVAKR
1760 1770 1780 1790 1800
NMTLPGENGQ NLVEWRFRKE QAQGKVNVFG RKLRVNGRNL LSVDFDRTTK
1810 1820 1830 1840 1850
TEKIYDDHRK FLLRIAYDTS GHPTLWLPSS KLMAVNVTYS STGQIASIQR
1860 1870 1880 1890 1900
GTTSEKVDYD SQGRIVSRVF ADGKTWSYTY LEKSMVLLLH SQRQYIFEYD
1910 1920 1930 1940 1950
MWDRLSAITM PSVARHTMQT IRSIGYYRNI YNPPESNASI ITDYNEEGLL
1960 1970 1980 1990 2000
LQTAFLGTSR RVLFKYRRQT RLSEILYDST RVSFTYDETA GVLKTVNLQS
2010 2020 2030 2040 2050
DGFICTIRYR QIGPLIDRQI FRFSEDGMVN ARFDYSYDNS FRVTSMQGVI
2060 2070 2080 2090 2100
NETPLPIDLY QFDDISGKVE QFGKFGVIYY DINQIISTAV MTYTKHFDAH
2110 2120 2130 2140 2150
GRIKEIQYEI FRSLMYWITI QYDNMGRVTK REIKIGPFAN TTKYAYEYDV
2160 2170 2180 2190 2200
DGQLQTVYLN EKIMWRYNYD LNGNLHLLNP SSSARLTPLR YDLRDRITRL
2210 2220 2230 2240 2250
GDVQYRLDED GFLRQRGTEI FEYSSKGLLT RVYSKGSGWT VIYRYDGLGR
2260 2270 2280 2290 2300
RVSSKTSLGQ HLQFFYADLT YPTRITHVYN HSSSEITSLY YDLQGHLFAM
2310 2320 2330 2340 2350
EISSGDEFYI ASDNTGTPLA VFSSNGLMLK QTQYTAYGEI YFDSNVDFQL
2360 2370 2380 2390 2400
VIGFHGGLYD PLTKLIHFGE RDYDILAGRW TTPDIEIWKR IGKDPAPFNL
2410 2420 2430 2440 2450
YMFRNNNPAS KIHDVKDYIT DVNSWLVTFG FHLHNAIPGF PVPKFDLTEP
2460 2470 2480 2490 2500
SYELVKSQQW EDVPPIFGVQ QQVARQAKAF LSLGKMAEVQ VSRRKAGAEQ
2510 2520 2530 2540 2550
SWLWFATVKS LIGKGVMLAV SQGRVQTNVL NIANEDCIKV AAVLNNAFYL
2560 2570 2580 2590 2600
ENLHFTIEGK DTHYFIKTTT PESDLGTLRL TSGRKALENG INVTVSQSTT
2610 2620 2630 2640 2650
VVNGRTRRFA DVEMQFGALA LHVRYGMTLD EEKARILEQA RQRALARAWA
2660 2670 2680 2690 2700
REQQRVRDGE EGARLWTEGE KRQLLSAGKV QGYDGYYVLS VEQYPELADS
2710
ANNIQFLRQS EIGKR
Length:2,715
Mass (Da):303,066
Last modified:November 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i598F46A77334C2E1
GO
Isoform A0B01 Publication (identifier: Q9WTS6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     741-749: Missing.
     1219-1225: Missing.

Show »
Length:2,699
Mass (Da):301,043
Checksum:i56D7679CB2B5BB47
GO
Isoform A0B11 Publication (identifier: Q9WTS6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     741-749: Missing.

Show »
Length:2,706
Mass (Da):301,997
Checksum:iEDA39911FEA75680
GO
Isoform A1B01 Publication (identifier: Q9WTS6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1219-1226: RNKDFRHS → S

Show »
Length:2,708
Mass (Da):302,112
Checksum:i571756DE38F48115
GO
Isoform A2B11 Publication (identifier: Q9WTS6-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     749-749: K → KDKIGYK

Show »
Length:2,721
Mass (Da):303,771
Checksum:i9283595CCF69008D
GO
Isoform A2B01 Publication (identifier: Q9WTS6-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     749-749: K → KDKIGYK
     1219-1226: RNKDFRHS → S

Show »
Length:2,714
Mass (Da):302,817
Checksum:iCB89670E82907698
GO
Isoform A3B11 Publication (identifier: Q9WTS6-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     749-749: K → KADKIGYK

Show »
Length:2,722
Mass (Da):303,842
Checksum:i770F2925A7CA9972
GO
Isoform A3B01 Publication (identifier: Q9WTS6-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     749-749: K → KADKIGYK
     1219-1226: RNKDFRHS → S

Show »
Length:2,715
Mass (Da):302,888
Checksum:i7425FC363BF32174
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3X907G3X907_MOUSE
Teneurin-3
Tenm3 Odz3
2,715Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7ZNJ5B7ZNJ5_MOUSE
Odz3 protein
Tenm3 Odz3
2,699Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YW49D3YW49_MOUSE
Teneurin-3
Tenm3 Odz3
495Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YW50D3YW50_MOUSE
Teneurin-3
Tenm3 Odz3
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RM36A0A1D5RM36_MOUSE
Teneurin-3
Tenm3
159Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RM80A0A1D5RM80_MOUSE
Teneurin-3
Tenm3
169Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAE22691 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1632 – 1637LLATKS → AFSHQK in BAE22691 (PubMed:16141072).Curated6
Sequence conflicti1640T → S in BAE23200 (PubMed:16141072).Curated1
Sequence conflicti2332T → I in AAF28316 (PubMed:10625539).Curated1
Sequence conflicti2332T → I in BAE23200 (PubMed:16141072).Curated1
Sequence conflicti2332T → I in BAC65795 (PubMed:16141072).Curated1
Sequence conflicti2482Missing in BAC27329 (PubMed:16141072).Curated1
Sequence conflicti2636I → L in BAB27919 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_021402741 – 749Missing in isoform A0B0 and isoform A0B1. 2 Publications1 Publication9
Alternative sequenceiVSP_059560749K → KDKIGYK in isoform A2B1 and isoform A2B0. 1 Publication1
Alternative sequenceiVSP_059561749K → KADKIGYK in isoform A3B1 and isoform A3B0. 1 Publication1
Alternative sequenceiVSP_0595621219 – 1226RNKDFRHS → S in isoform A1B0, isoform A2B0 and isoform A3B0. 1 Publication8
Alternative sequenceiVSP_0214031219 – 1225Missing in isoform A0B0. 2 Publications7

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB025412 mRNA Translation: BAA77398.1
AF195418 mRNA Translation: AAF28316.1
MG387139 mRNA Translation: AUQ44320.1
MG387140 mRNA Translation: AUQ44321.1
MG387141 mRNA Translation: AUQ44322.1
MG387142 mRNA Translation: AUQ44323.1
MG387143 mRNA Translation: AUQ44324.1
MG387144 mRNA Translation: AUQ44325.1
MG387145 mRNA Translation: AUQ44326.1
MG387146 mRNA Translation: AUQ44327.1
AK011924 mRNA Translation: BAB27919.1
AK031268 mRNA Translation: BAC27329.1
AK122513 mRNA Translation: BAC65795.1
AK135844 mRNA Translation: BAE22691.1 Different initiation.
AK136994 mRNA Translation: BAE23200.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS22303.1 [Q9WTS6-1]
CCDS85538.1 [Q9WTS6-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB025412 mRNA Translation: BAA77398.1
AF195418 mRNA Translation: AAF28316.1
MG387139 mRNA Translation: AUQ44320.1
MG387140 mRNA Translation: AUQ44321.1
MG387141 mRNA Translation: AUQ44322.1
MG387142 mRNA Translation: AUQ44323.1
MG387143 mRNA Translation: AUQ44324.1
MG387144 mRNA Translation: AUQ44325.1
MG387145 mRNA Translation: AUQ44326.1
MG387146 mRNA Translation: AUQ44327.1
AK011924 mRNA Translation: BAB27919.1
AK031268 mRNA Translation: BAC27329.1
AK122513 mRNA Translation: BAC65795.1
AK135844 mRNA Translation: BAE22691.1 Different initiation.
AK136994 mRNA Translation: BAE23200.1
CCDSiCCDS22303.1 [Q9WTS6-1]
CCDS85538.1 [Q9WTS6-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6FAYelectron microscopy3.80A845-2715[»]
SMRiQ9WTS6
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiQ9WTS6, 1 interactor
STRINGi10090.ENSMUSP00000140141

PTM databases

GlyConnecti2431, 3 N-Linked glycans (2 sites) [Q9WTS6-2]
2757, 4 N-Linked glycans (2 sites)
GlyGeniQ9WTS6, 17 sites, 4 N-linked glycans (2 sites)
iPTMnetiQ9WTS6
PhosphoSitePlusiQ9WTS6

Proteomic databases

PaxDbiQ9WTS6
PRIDEiQ9WTS6
ProteomicsDBi258991 [Q9WTS6-1]
258992 [Q9WTS6-2]

Organism-specific databases

MGIiMGI:1345183, Tenm3

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG4659, Eukaryota
InParanoidiQ9WTS6
PhylomeDBiQ9WTS6

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Tenm3, mouse

Protein Ontology

More...
PROi
PR:Q9WTS6
RNActiQ9WTS6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

Gene3Di2.120.10.30, 2 hits
InterProiView protein in InterPro
IPR011042, 6-blade_b-propeller_TolB-like
IPR008969, CarboxyPept-like_regulatory
IPR000742, EGF-like_dom
IPR022385, Rhs_assc_core
IPR027691, Ten-3/4
IPR009471, Ten_N
IPR028916, Tox-GHH_dom
IPR006530, YD
PANTHERiPTHR11219:SF65, PTHR11219:SF65, 1 hit
PfamiView protein in Pfam
PF06484, Ten_N, 2 hits
PF15636, Tox-GHH, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 8 hits
SUPFAMiSSF49464, SSF49464, 1 hit
TIGRFAMsiTIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 2 hits
PROSITEiView protein in PROSITE
PS00022, EGF_1, 8 hits
PS01186, EGF_2, 7 hits
PS50026, EGF_3, 5 hits
PS51361, TENEURIN_N, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTEN3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9WTS6
Secondary accession number(s): A0A2K9QKY6
, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 1, 1999
Last modified: September 29, 2021
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again