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Protein

Putative transcription factor Ovo-like 1

Gene

Ovol1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri118 – 140C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri146 – 168C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri174 – 197C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri213 – 236C2H2-type 4PROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transcription factor Ovo-like 1
Short name:
mOvo1
Short name:
mOvo1a
Gene namesi
Name:Ovol1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1330290 Ovol1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000470121 – 267Putative transcription factor Ovo-like 1Add BLAST267

Proteomic databases

PaxDbiQ9WTJ2
PRIDEiQ9WTJ2

PTM databases

iPTMnetiQ9WTJ2
PhosphoSitePlusiQ9WTJ2

Expressioni

Tissue specificityi

Expressed in skin, testis, kidney and weakly in lung. Not detected in heart, brain, spleen, liver and skeletal muscle.

Developmental stagei

First expressed at E14.5 day in the suprabasal layers of developing epidermis, at E15.5 expression begins in the inner cells of developing hair germs and restricted to inner root sheath and/or precortical cells of developing hair follicles.

Gene expression databases

BgeeiENSMUSG00000024922 Expressed in 98 organ(s), highest expression level in skin of back
CleanExiMM_OVOL1
GenevisibleiQ9WTJ2 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025861

Structurei

3D structure databases

ProteinModelPortaliQ9WTJ2
SMRiQ9WTJ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri118 – 140C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri146 – 168C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri174 – 197C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri213 – 236C2H2-type 4PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG3576 Eukaryota
ENOG4111H28 LUCA
GeneTreeiENSGT00920000149010
HOGENOMiHOG000231694
HOVERGENiHBG053384
InParanoidiQ9WTJ2
KOiK09216
OMAiQPYQEPE
OrthoDBiEOG091G0LB1
PhylomeDBiQ9WTJ2
TreeFamiTF337552

Family and domain databases

InterProiView protein in InterPro
IPR027756 Ovo-like
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR10032 PTHR10032, 1 hit
PfamiView protein in Pfam
PF00096 zf-C2H2, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 4 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequencei

Sequence statusi: Complete.

Q9WTJ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRAFLVKKP CVSTCKRNWS ELPDEERGEI YVPVSLGFCP PQPYREPEAS
60 70 80 90 100
VAEPPSCPLA LDMSLRDSSY SVAPGPCVVA QLPSEDVSHL TDPQSRDQGF
110 120 130 140 150
LRTKMKVTLG DSPNGDLFTC HICQKSFTHQ RMLNRHMKCH NDVKRHLCTY
160 170 180 190 200
CGKGFNDTFD LKRHVRTHTG VRPYKCSLCD KAFTQRCSLE SHLKKIHGVQ
210 220 230 240 250
QKYAYKERRA KLYVCEECGC TSESQEGHVL HLKERHPDSP LLRKTSKKVA
260
VALQNTVTSL LQGSPHL
Length:267
Mass (Da):30,222
Last modified:November 1, 1999 - v1
Checksum:iDAD4F51150C21C2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF134804 mRNA Translation: AAD29689.1
AF134805 mRNA Translation: AAD29690.1
AK003801 mRNA Translation: BAB23003.1
AK028577 mRNA Translation: BAC26015.1
AK132478 mRNA Translation: BAE21188.1
AK132505 mRNA Translation: BAE21208.1
AK132506 mRNA Translation: BAE21209.1
BC021411 mRNA Translation: AAH21411.1
CCDSiCCDS29469.1
RefSeqiNP_064319.1, NM_019935.3
UniGeneiMm.280225

Genome annotation databases

EnsembliENSMUST00000025861; ENSMUSP00000025861; ENSMUSG00000024922
GeneIDi18426
KEGGimmu:18426
UCSCiuc008gdu.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF134804 mRNA Translation: AAD29689.1
AF134805 mRNA Translation: AAD29690.1
AK003801 mRNA Translation: BAB23003.1
AK028577 mRNA Translation: BAC26015.1
AK132478 mRNA Translation: BAE21188.1
AK132505 mRNA Translation: BAE21208.1
AK132506 mRNA Translation: BAE21209.1
BC021411 mRNA Translation: AAH21411.1
CCDSiCCDS29469.1
RefSeqiNP_064319.1, NM_019935.3
UniGeneiMm.280225

3D structure databases

ProteinModelPortaliQ9WTJ2
SMRiQ9WTJ2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025861

PTM databases

iPTMnetiQ9WTJ2
PhosphoSitePlusiQ9WTJ2

Proteomic databases

PaxDbiQ9WTJ2
PRIDEiQ9WTJ2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025861; ENSMUSP00000025861; ENSMUSG00000024922
GeneIDi18426
KEGGimmu:18426
UCSCiuc008gdu.1 mouse

Organism-specific databases

CTDi5017
MGIiMGI:1330290 Ovol1

Phylogenomic databases

eggNOGiKOG3576 Eukaryota
ENOG4111H28 LUCA
GeneTreeiENSGT00920000149010
HOGENOMiHOG000231694
HOVERGENiHBG053384
InParanoidiQ9WTJ2
KOiK09216
OMAiQPYQEPE
OrthoDBiEOG091G0LB1
PhylomeDBiQ9WTJ2
TreeFamiTF337552

Miscellaneous databases

PROiPR:Q9WTJ2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024922 Expressed in 98 organ(s), highest expression level in skin of back
CleanExiMM_OVOL1
GenevisibleiQ9WTJ2 MM

Family and domain databases

InterProiView protein in InterPro
IPR027756 Ovo-like
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR10032 PTHR10032, 1 hit
PfamiView protein in Pfam
PF00096 zf-C2H2, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 4 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiOVOL1_MOUSE
AccessioniPrimary (citable) accession number: Q9WTJ2
Secondary accession number(s): Q545S2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: November 7, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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