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Protein
Submitted name:

DEAD-box RNA helicase

Gene

DDX5

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-GGA-72163 mRNA Splicing - Major Pathway
R-GGA-9018519 Estrogen-dependent gene expression

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD-box RNA helicaseImported
Submitted name:
DEAD-box helicase 5Imported
Gene namesi
Name:DDX5Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 18

Expressioni

Gene expression databases

BgeeiENSGALG00000003532
ExpressionAtlasiQ9W744 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000034001

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini82 – 110Q_MOTIFInterPro annotationAdd BLAST29
Domaini113 – 288Helicase ATP-bindingInterPro annotationAdd BLAST176
Domaini316 – 463Helicase C-terminalInterPro annotationAdd BLAST148

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi82 – 110Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0331 Eukaryota
COG0513 LUCA
GeneTreeiENSGT00920000149008
HOGENOMiHOG000268804
HOVERGENiHBG015893
KOiK12823
OrthoDBiEOG091G033A

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR033488 DDX5
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR012587 P68_rpt
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PANTHERiPTHR24031:SF404 PTHR24031:SF404, 1 hit
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
PF08061 P68HR, 2 hits
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SM01414 P68HR, 2 hits
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequencei

Sequence statusi: Complete.

Q9W744-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGFGAPRFG GSRAGPLSGK KFGNPGEKLT KKKWNLDELP KFEKNFYQEH
60 70 80 90 100
PDVVRRTAQE VEQYRSSKEV TVRGHNCPKP IINFYEANFP ANVMEVIQRQ
110 120 130 140 150
NFTEPTAIQA QGWPVALSGL DMVGVAQTGS GKTLSYLLPA IVHINHQPFL
160 170 180 190 200
ERGDGPICLV LAPTRELAQQ VQQVAAEYSR ACRLKSTCIY GGAPKGPQIR
210 220 230 240 250
DLERGVEICI ATPGRLIDFL EAGKTNLRRC TYLVLDEADR MLDMGFEPQI
260 270 280 290 300
RKIVDQIRPD RQTLMWSATW PKEVRQLAED FLKEYVHINI GALELSANHN
310 320 330 340 350
ILQIVDVCHD VEKDDKLIRL MEEIMSEKEN KTIVFVETKR RCDDLTRKMR
360 370 380 390 400
RDGWPAMGIH GDKSQQERDW VLNEFKHGKA PILIATDVAS RGLDVEDVKF
410 420 430 440 450
VINYDYPNSS EDYIHRIGRT ARSTKTGTAY TFFTPNNIKQ VNDLISVLRE
460 470 480 490 500
ANQAINPKLL QLIEDRGSGR SRGDRRDRYS AGKRGGFSSF RERENFERTY
510 520 530 540 550
GALGKRDFGA KAQNGAYSTQ SFSNGTPFGN GFAAAGMQAG FRAGNPAGAY
560 570 580 590
QNGYDQQYGS NIANMHNGMN QQQYAYPATG AAPMIGYPMP ASYSQ
Length:595
Mass (Da):66,736
Last modified:November 1, 1999 - v1
Checksum:iB98192334B6F6201
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000212 Genomic DNA No translation available.
AF158370 mRNA Translation: AAD40318.1
RefSeqiNP_990158.1, NM_204827.1
UniGeneiGga.4548

Genome annotation databases

EnsembliENSGALT00000005586; ENSGALP00000005576; ENSGALG00000003532
GeneIDi395629
KEGGigga:395629

Similar proteinsi

Entry informationi

Entry nameiQ9W744_CHICK
AccessioniPrimary (citable) accession number: Q9W744
Secondary accession number(s): F1NM08
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: June 20, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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