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Entry version 147 (02 Jun 2021)
Sequence version 3 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein, isoform C

Gene

Dmel\CG5937

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein, isoform CImported
Submitted name:
Uncharacterized protein, isoform DImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dmel\CG5937Imported
ORF Names:CG5937Imported, Dmel_CG5937Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0029834, CG5937

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0029834, Expressed in head and 17 other tissues

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini451 – 692SEC7InterPro annotationAdd BLAST242

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni493 – 540DisorderedSequence analysisAdd BLAST48
Regioni903 – 927DisorderedSequence analysisAdd BLAST25
Regioni1232 – 1252DisorderedSequence analysisAdd BLAST21
Regioni1507 – 1533DisorderedSequence analysisAdd BLAST27
Regioni1892 – 1940DisorderedSequence analysisAdd BLAST49
Regioni1961 – 1983DisorderedSequence analysisAdd BLAST23

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1507 – 1522Polar residuesSequence analysisAdd BLAST16
Compositional biasi1908 – 1940Polar residuesSequence analysisAdd BLAST33

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1846, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000167889

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000867_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
TCCWDSM

Database of Orthologous Groups

More...
OrthoDBi
40522at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR015403, Sec7_C
IPR000904, Sec7_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09324, DUF1981, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00222, Sec7, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9W444-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEDLFLLIIK ESTGTKHNAL RQTAQIAYDK LYRQHGIHRD PSHELRSVCF
60 70 80 90 100
TALQMALDTK RPKFITMGLN GLHRVIKDER FYIGLEPEDD SVWLPSQLLR
110 120 130 140 150
ATNGILPTTS SEDTVVNVLR LFLAMACSPA CTLNGRLLIE ILSRCGECWE
160 170 180 190 200
MGSRATKAAS LAAASQCLRT FCAFLIEEAE EVKKTAPAGL MTQTQASAVY
210 220 230 240 250
NEVIPVMQWL CSRLVEPNVN ASPNKKCENH SSLYLTECIL TLSSALPRNV
260 270 280 290 300
HANPHFTSFL WQKFCPTLAA ALGSPGRINL DKKFTYKDAL HMIENEARGF
310 320 330 340 350
FTGPGLDGPQ ARCVYLTAIQ LLRIAGAHGS LRPMLEALFH RMLLLPAPQN
360 370 380 390 400
RTEPLRCVRE IFKSPERLID LAVILYVDKN TAQGCSDEMA LFRLLVDAME
410 420 430 440 450
ECAYGASGGG SATEASLQAS VECMVALLDS LQVLCSGELT ESMISDQIVQ
460 470 480 490 500
VVNGRHDLLK DADYSGPLTY QSMARLPAPY RDAIVEFRQT VFETSSGSES
510 520 530 540 550
EGEPQHEQDA ASNGSGDTEG PEDDDPSSSS DETSRVENRW PYSHLEAPVM
560 570 580 590 600
PIRTDSDNDR QHARDFARAL RQDLVPKLLR LRSCVELDEA MQEFASAVCQ
610 620 630 640 650
ENSMNFSDFD YNLTAINADG IYLAIYSSLL LSLQLMRAGF YEQVAQGMSH
660 670 680 690 700
KDILVPMSEQ QFVTSVQNTG VLVYLSSPWL CELYQSVTVC NVLEAMPRQQ
710 720 730 740 750
LEGMGPRCAL VDMLCDAGGL GATQMLSEWQ RLQTANVKHK EEEQLHDKRR
760 770 780 790 800
EAAKKLCRRL LTCCWDSMVI VLSSGLGDLQ TSSASNKLVA LSKRTLRVKA
810 820 830 840 850
KANKSNGEAL YAMCLDGLHS AATLSNSLNL QHLAGKILNL LASNVCQTSG
860 870 880 890 900
PRISASQAMS MDVVLTGGLN LGSYSADCWP SIFAVCRHVS QLEHEIFSMQ
910 920 930 940 950
NPAISASPGS SRRDLETGEK LSNGNAQDKL NLSSIPIDDD ETCVDVYSFL
960 970 980 990 1000
QAPMQSPNTN ITSILKVYSG TNETVLLSQS DTSKVLCALS HQAENLFGDA
1010 1020 1030 1040 1050
AERLSLPSLC QFLKHLCRAS RDQLYKSQVA RKGSRIWWPS KGWKKLDSLP
1060 1070 1080 1090 1100
MSLLLHRIGD VTLKVFRSSR PLLHVLKVWA ITGPHLMDAA CHRDRMISKR
1110 1120 1130 1140 1150
AIEYIHDIIT ALLVEQSELP YFHFNEALLK PFENLLSMDT DVDVQDQIVA
1160 1170 1180 1190 1200
CLYEVVEAHR TEIRSGWRPL FGTLRNARSR MLNMSNIIDI FRVFLDSDNT
1210 1220 1230 1240 1250
LVFANAGLDC ILCLLSYLEI SGGGNNNACS GGSGSAAGGT ASNGGQQEED
1260 1270 1280 1290 1300
NTFRPTDFLH ETLRFLERCS SILGFMHSMP KCPNFHSTYK IKGISYTHII
1310 1320 1330 1340 1350
DANIPSSMEN FTYFGNDYLQ TRNEQYMISY RSLHIDKDTI VKIDEMDKPS
1360 1370 1380 1390 1400
GVLKVWFLLL DGLTNSLIVC PYSHQAPILQ TIFKLFKNLL ASPGIDFGFY
1410 1420 1430 1440 1450
CINHLLVPMI QDWLRYINKT GSSWQLVEKN FKHCCCMTTD LVVEFIEKSV
1460 1470 1480 1490 1500
PEQRRLGAGT KTRLAQIVHP ADNLLYSKLK FVTERIEREQ QQQQSPSVQD
1510 1520 1530 1540 1550
HGCGYTQQYD SSSSSASEEQ QKNGGGVGGG GSNLIESPTK ISGSATLALK
1560 1570 1580 1590 1600
QLLLVLIECA AQSQEAIARI SVSCLKHVIL STGMLFNESQ WMIACSAIHR
1610 1620 1630 1640 1650
ACTVTIAPLR QLSFAFHEKS NSFYGDCANV KVAARRDSSL EELARIYALA
1660 1670 1680 1690 1700
QQVFLSDNQR EPGQNQAPTP SASQCKLSDD RSYSFLLYPL NNGFNSNLDN
1710 1720 1730 1740 1750
FVIRIPFKNL VVGLLANQML LQLVAKLLLS RLKCVPQAVS TCIFDNYAAS
1760 1770 1780 1790 1800
AASPSHDYDL DFRSKEILLR CVKQYLMSAL EFDSRPGLKF LMQKVSNIEY
1810 1820 1830 1840 1850
AANLYKQMTS SWMIYYIALV DSHLNDIVVY NLGPEDLNFI LESCSRLNTT
1860 1870 1880 1890 1900
TVKKKENFVR YLFCLQDAWN LVCELYLSNS ALHEIESGSG KLRQKPPQLL
1910 1920 1930 1940 1950
HHPQTKPMCI SLNGNGDAEM TDTGSGSGSG SSTSPSKCVQ LQEEENVTMT
1960 1970 1980 1990 2000
TLISEFQPKC RSNPFDTNRQ AKSSEAESIS PEIEQQRASS ILKDSNYKRA
2010 2020 2030 2040 2050
ALAQLVVASM ELLRSLPGEA EENLKLLMTP TIREAFRLVQ LQGNELKVNQ

F
Length:2,051
Mass (Da):227,953
Last modified:June 26, 2013 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iACF3B07FC04A5698
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46115.3
AE014298 Genomic DNA Translation: ABW09341.2

NCBI Reference Sequences

More...
RefSeqi
NP_001096888.2, NM_001103418.3
NP_572289.2, NM_132061.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0305345; FBpp0293888; FBgn0029834
FBtr0305346; FBpp0293889; FBgn0029834

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
31537

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5937

UCSC genome browser

More...
UCSCi
CG5937-RA, d. melanogaster
CG5937-RB, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46115.3
AE014298 Genomic DNA Translation: ABW09341.2
RefSeqiNP_001096888.2, NM_001103418.3
NP_572289.2, NM_132061.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
31537

Genome annotation databases

EnsemblMetazoaiFBtr0305345; FBpp0293888; FBgn0029834
FBtr0305346; FBpp0293889; FBgn0029834
GeneIDi31537
KEGGidme:Dmel_CG5937
UCSCiCG5937-RA, d. melanogaster
CG5937-RB, d. melanogaster

Organism-specific databases

FlyBaseiFBgn0029834, CG5937

Phylogenomic databases

eggNOGiKOG1846, Eukaryota
GeneTreeiENSGT00940000167889
HOGENOMiCLU_000867_0_0_1
OMAiTCCWDSM
OrthoDBi40522at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
31537, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
31537

Gene expression databases

BgeeiFBgn0029834, Expressed in head and 17 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR015403, Sec7_C
IPR000904, Sec7_dom
PfamiView protein in Pfam
PF09324, DUF1981, 1 hit
SMARTiView protein in SMART
SM00222, Sec7, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9W444_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W444
Secondary accession number(s): A8JUY6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: June 26, 2013
Last modified: June 2, 2021
This is version 147 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
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