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Protein

60S ribosomal protein L17

Gene

RpL17

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L17
Gene namesi
Name:RpL17
ORF Names:CG3203
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0029897 RpL17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003234121 – 18660S ribosomal protein L17Add BLAST186

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei158Phosphoserine1 Publication1
Modified residuei161Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9W3W8
PRIDEiQ9W3W8

PTM databases

iPTMnetiQ9W3W8

Expressioni

Gene expression databases

BgeeiFBgn0029897
ExpressionAtlasiQ9W3W8 baseline and differential
GenevisibleiQ9W3W8 DM

Interactioni

Protein-protein interaction databases

BioGridi58099, 33 interactors
IntActiQ9W3W8, 19 interactors
MINTiQ9W3W8
STRINGi7227.FBpp0070940

Structurei

3D structure databases

ProteinModelPortaliQ9W3W8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3353 Eukaryota
COG0091 LUCA
InParanoidiQ9W3W8
KOiK02880
OMAiANAEYKG
OrthoDBiEOG091G0FOW
PhylomeDBiQ9W3W8

Family and domain databases

CDDicd00336 Ribosomal_L22, 1 hit
Gene3Di3.90.470.10, 1 hit
InterProiView protein in InterPro
IPR001063 Ribosomal_L22
IPR018260 Ribosomal_L22/L17_CS
IPR005721 Ribosomal_L22/L17_euk/arc
IPR036394 Ribosomal_L22/L17_sf
PANTHERiPTHR11593 PTHR11593, 1 hit
PfamiView protein in Pfam
PF00237 Ribosomal_L22, 1 hit
SUPFAMiSSF54843 SSF54843, 1 hit
TIGRFAMsiTIGR01038 uL22_arch_euk, 1 hit
PROSITEiView protein in PROSITE
PS00464 RIBOSOMAL_L22, 1 hit

Sequencei

Sequence statusi: Complete.

Q9W3W8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRYSRESDN VAKSCKARGP NLRVHFKNTH ETAQAIKRMP LRRAQRYLKA
60 70 80 90 100
VIDQKECVPF RRFNGGVGRC AQAKQWKTTQ GRWPKKSAEF LLQLLRNAEA
110 120 130 140 150
NADCKGLDAD RLVVHHIQVN RAQCLRRRTY RAHGRINPYM SSPCHVEVIL
160 170 180
TEKEELVSKA TDDEPAKKKL SKKKLQRQKE KMLRSE
Length:186
Mass (Da):21,593
Last modified:May 1, 2000 - v1
Checksum:i686083C4AD924544
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46194.1
AE014298 Genomic DNA Translation: AAF46195.1
AE014298 Genomic DNA Translation: AAN09182.1
AE014298 Genomic DNA Translation: AAN09183.1
AY060845 mRNA Translation: AAL28393.1
RefSeqiNP_001284961.1, NM_001298032.1
NP_572346.1, NM_132118.3
NP_727118.1, NM_167087.1
NP_727119.1, NM_167088.2
NP_727120.1, NM_167089.2
UniGeneiDm.7261

Genome annotation databases

EnsemblMetazoaiFBtr0070980; FBpp0070940; FBgn0029897
FBtr0070981; FBpp0070941; FBgn0029897
FBtr0070982; FBpp0070942; FBgn0029897
FBtr0070983; FBpp0070943; FBgn0029897
FBtr0345292; FBpp0311459; FBgn0029897
GeneIDi31613
KEGGidme:Dmel_CG3203

Similar proteinsi

Entry informationi

Entry nameiRL17_DROME
AccessioniPrimary (citable) accession number: Q9W3W8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: May 1, 2000
Last modified: July 18, 2018
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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