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Entry version 121 (16 Oct 2019)
Sequence version 3 (05 Jul 2004)
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Protein
Submitted name:

PIP82

Gene

PIP82

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
PIP82Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PIP82Imported
Synonyms:Dmel\CG11219Imported
ORF Names:CG11219Imported, Dmel_CG11219Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0024943 PIP82

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9W3E2

PRoteomics IDEntifications database

More...
PRIDEi
Q9W3E2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
FBgn0024943 Expressed in 6 organ(s), highest expression level in head

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q9W3E2 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q9W3E2, 3 interactors

STRING: functional protein association networks

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STRINGi
7227.FBpp0071179

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 55DisorderedSequence analysisAdd BLAST55
Regioni85 – 132DisorderedSequence analysisAdd BLAST48
Regioni291 – 471DisorderedSequence analysisAdd BLAST181
Regioni493 – 515DisorderedSequence analysisAdd BLAST23
Regioni544 – 567DisorderedSequence analysisAdd BLAST24
Regioni612 – 637DisorderedSequence analysisAdd BLAST26
Regioni702 – 771DisorderedSequence analysisAdd BLAST70
Regioni833 – 977DisorderedSequence analysisAdd BLAST145
Regioni1060 – 1195DisorderedSequence analysisAdd BLAST136

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili253 – 273Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi12 – 26BasicSequence analysisAdd BLAST15
Compositional biasi291 – 314PolyampholyteSequence analysisAdd BLAST24
Compositional biasi359 – 373Pro-richSequence analysisAdd BLAST15
Compositional biasi420 – 435BasicSequence analysisAdd BLAST16
Compositional biasi442 – 458PolyampholyteSequence analysisAdd BLAST17
Compositional biasi544 – 561PolarSequence analysisAdd BLAST18
Compositional biasi702 – 716PolarSequence analysisAdd BLAST15
Compositional biasi852 – 868PolarSequence analysisAdd BLAST17
Compositional biasi877 – 892AcidicSequence analysisAdd BLAST16
Compositional biasi897 – 943Pro-richSequence analysisAdd BLAST47
Compositional biasi944 – 965PolarSequence analysisAdd BLAST22
Compositional biasi1060 – 1083PolarSequence analysisAdd BLAST24
Compositional biasi1084 – 1098PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1099 – 1156PolarSequence analysisAdd BLAST58
Compositional biasi1174 – 1189PolarSequence analysisAdd BLAST16

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410KBCB Eukaryota
ENOG4110NE9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000033589

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9W3E2

Identification of Orthologs from Complete Genome Data

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OMAi
PRVLIHQ

Database of Orthologous Groups

More...
OrthoDBi
168474at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9W3E2

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9W3E2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHQEQQFQH YPHHQHHHHH HHHHIHQVQS ETQLEQRSSD LEPNRSRNTD
60 70 80 90 100
RIGSSMDFRN LCQRIDVDGL KAKLPQLKLP KSLPKLRGRK IFRSSKSGSN
110 120 130 140 150
AAGGGTAGGS AKDGAGAAQQ THLQVAGQSQ QFINRTPQRI STISSLMYEG
160 170 180 190 200
EQEEIRANLG QSQPGTYRSA GSLDDDYYAP GSGDRASRPI SPIKIPVVGA
210 220 230 240 250
LDDSSPSENG NVRTTFTQRL QRGYKSLSEL RIKHIFAKQT TVRRDNIEVD
260 270 280 290 300
RYVEQYEREL KSEKLARERR DREIAENYDI KIKTLAGTRQ NTFDDDDVEH
310 320 330 340 350
EQFERGKISH ETDESGMEAT PPLPSRRKPG IAATRFAKVR KPPLEMEEEQ
360 370 380 390 400
QQAAAEESPQ ANPPPPPPPR PSSYKQLLIN KLPHLPSLPN LPQFSRTKEE
410 420 430 440 450
TTKTAENADE NNASRKLSIR QNIKRLRKSI KRPSKIKSKA AAPVPDSDEE
460 470 480 490 500
EATPDGQKTK DAPTRSSTAN LRARLSRFAS TEQLQQRWRK SFKVAKEPEE
510 520 530 540 550
LETKAEGSAT GGASGVLGGL LVGSQLEKTL AKLNEKVHQL KFFQRNANNQ
560 570 580 590 600
NATTSKQPKP NTVGHEPIEI DDDELEATYH RSDSLEAENG NGNENDDSGE
610 620 630 640 650
DISAEEAFGQ IQEEDNEEDH SQDQTKRGQS SVSGIATAHA ARQMAKLAEI
660 670 680 690 700
QAASKSGAAA WSSESLEEIA DEDYPRVLIH QEHSDAYEST LIIAVASKGS
710 720 730 740 750
SMSPVVRSSG LKSSPAAGPK TSPHPEIRIS ASGPQKSMSY SPGNPRGEPV
760 770 780 790 800
TKRSPSPEFK TPAGGNKIVP KSETSAWLPN EQIIAGFKEQ TSWPAPALYK
810 820 830 840 850
PKSIDIFEAS AGGSAAFADF DEALRNAPVL RISAGSSIDT SGEEADDSCS
860 870 880 890 900
RVTRIRVQSP QIGNSRESLM AQEEEDKEAE RDSEEEEEER DPSERPPSES
910 920 930 940 950
PPPPPLPQRR PPTKRPATPP IYDAVPPPLP VSKPPPPPSV ETIPSVASLP
960 970 980 990 1000
SPAPVTRSMA QRSASMSRPA KPLVKTSSLR LTYNEQVRPG DVGKVNKLIS
1010 1020 1030 1040 1050
RFEGGRPRLC PRRMHSEEYE RCAQPEDEEP EMEQILELQI IERRAVDSVT
1060 1070 1080 1090 1100
PTNRAVVIPQ ITVNNNNNNE RQLEQSDQSD QSAHQEITDT RKTKSMELAL
1110 1120 1130 1140 1150
DRQNSNCSRS EYGSPLSFPS SRRSSTPTNL NANSNSNPNP STNPNQNPSQ
1160 1170 1180 1190
ILQHQRRSRR SMTRDDDNFY SFDSDEENSY YSISPSGSSR YVVEI
Length:1,195
Mass (Da):132,341
Last modified:July 5, 2004 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE25DAA951839481C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46386.3

NCBI Reference Sequences

More...
RefSeqi
NP_572487.3, NM_132259.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0071235; FBpp0071179; FBgn0024943

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
31791

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG11219

UCSC genome browser

More...
UCSCi
CG11219-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46386.3
RefSeqiNP_572487.3, NM_132259.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9W3E2, 3 interactors
STRINGi7227.FBpp0071179

Proteomic databases

PaxDbiQ9W3E2
PRIDEiQ9W3E2

Genome annotation databases

EnsemblMetazoaiFBtr0071235; FBpp0071179; FBgn0024943
GeneIDi31791
KEGGidme:Dmel_CG11219
UCSCiCG11219-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
31791
FlyBaseiFBgn0024943 PIP82

Phylogenomic databases

eggNOGiENOG410KBCB Eukaryota
ENOG4110NE9 LUCA
GeneTreeiENSGT00440000033589
InParanoidiQ9W3E2
OMAiPRVLIHQ
OrthoDBi168474at2759
PhylomeDBiQ9W3E2

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PIP82 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
31791

Gene expression databases

BgeeiFBgn0024943 Expressed in 6 organ(s), highest expression level in head
GenevisibleiQ9W3E2 DM

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9W3E2_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W3E2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: July 5, 2004
Last modified: October 16, 2019
This is version 121 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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