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Entry version 169 (29 Sep 2021)
Sequence version 2 (01 Mar 2001)
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Protein
Submitted name:

C11.1, isoform A

Gene

c11.1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
C11.1, isoform AImported
Submitted name:
C11.1, isoform BImported
Submitted name:
LD28902pImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:c11.1Imported
Synonyms:C11.1Imported, Dmel\CG12132Imported
ORF Names:CG12132Imported, Dmel_CG12132Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

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FlyBasei
FBgn0040236, c11.1

Eukaryotic Pathogen, Vector and Host Database Resources

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VEuPathDBi
VectorBase:FBgn0040236

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9W350

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0040236, Expressed in Malpighian tubule and 39 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9W350, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
Q9W350, 2 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0071261

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 45DisorderedSequence analysisAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi15 – 45Polar residuesSequence analysisAdd BLAST31

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2032, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000166577

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003168_0_1_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
NMVSFHN

Database of Orthologous Groups

More...
OrthoDBi
31329at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9W350

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9W350-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGRGVGGGG SGAATGGGSA NNKSAAGNSA ATGNADASTA TAAPNDKPTI
60 70 80 90 100
LEGVLHNIFD GLMDKEEQVR IAMQQAIVKI LETHPERAAE ILSEHRSQQP
110 120 130 140 150
KMTDQTVAML LDCIRRVVGA ETPLPPAANQ KLIDLALQEL TKNPEHLPLI
160 170 180 190 200
QNPAQRILVA IGRSSPESCE QVMEALQEKG TSTEGVAHFM LMQCLGLLAT
210 220 230 240 250
ENPAGVVPHI KAILSRSQPH LVGIRQDHIK QAHAYAIGRF SEALLEESGK
260 270 280 290 300
KEEENCSTEI SVAYDVLFNQ WLHSREPKVC VEILQALSSM YPLLPKDRIQ
310 320 330 340 350
DQAARLVPQI LALYRRSVDR NAVTQFLCSV LKTNLALNAT VLDGIIDVLV
360 370 380 390 400
THLFDLVCVY PDYEKPQTVK GHYEVLRCFH LLAGHQPYST RIMDTLLIHL
410 420 430 440 450
RNNSERERMK SLLILTHLLN SCAGNIENRI PATIECLKQL ILSERGIKMK
460 470 480 490 500
LTLLKTIVAL AQKSHIRDKE FVWFVVRHSC RFSKPSQEHG SQEEHANLVL
510 520 530 540 550
SCENTLYMLA STVGTLDELL KRELLNYLIL LDYTDICGNL AKCLASLFAK
560 570 580 590 600
SPHIEYDIAG DDAATEQATP ESMGAAGEDR SVIKRGKVMV PGAETIYARC
610 620 630 640 650
LALLGNQQCI KRCSNILSFL RYYHPQVNPA LEELWERKIP DLLLQINRES
660 670 680 690 700
AYRQLLHDFV LETNEFLGGL DENFAQRLAS KLADQMYLYP MQLPHSEWHL
710 720 730 740 750
PDLSAERGML LQAVALTLLQ VTDVACIHTK IDLIVTTARQ ERLDKHVKHA
760 770 780 790 800
DYEKRIEPCA RALGYISRQH LGHLIKKLTE LAQVGGRKHS TGFFSNLHFI
810 820 830 840 850
KDTHKELENY KSNLLVVKAF GRIMDEADPL QSIQHLDEDD TLLGFLIQQL
860 870 880 890 900
AVHKDQTIMS AILQTLLSIC NQLIATKEQL PAPLRHRKQI METVFNIPIE
910 920 930 940 950
APFHDLPLLP TILKLGTDFI RIGGPDTEEC VDGGVIFEIA CRNFFGCAQQ
960 970 980 990 1000
LKMKFDSQEE DERNSFLAKH LNESLPQLNA LVRAIVELDA SPATLDLIIG
1010 1020 1030 1040 1050
ILEGWTRDRN SEVRICASHV FNNTLDVYIK SMKIGCEAPS KFNQTGQMLG
1060 1070 1080 1090 1100
KIVPRCIDSN GTVRQVSVEI LQKTLEIACI YETLTIASID STADWLKEIE
1110 1120 1130 1140 1150
TIKEHIITDE PKQIYNLAGD IAKIIALRIS SFQYLQFCKT LLHSLRDPEQ
1160 1170 1180 1190 1200
SSTIGASVVL KFFIQQKGSE LFHAIPDLVR DSLLALRVCE VPRAKSGVLK
1210 1220 1230 1240 1250
ALVALTKHHP KLVCAEMLSQ PLPYDPNLVE YWHLVCNDPE LTGLTLDNFL
1260 1270 1280 1290 1300
QLLSGASLQE GGQDASLSER QKLASGQPFA IFCALHEMLP CKDIKGQLET
1310 1320 1330 1340 1350
RFADMFCMLL TSLSSYTNLA APNPINNASL SPNQTQSGKT KFGFVPNKEL
1360 1370 1380 1390 1400
IKLNPCQIAL ETFQAFLTNL EMEQIASVLT VNTQLASSAD WHNYIELLTP
1410 1420 1430 1440 1450
MAIGLGQQLQ LGSPQMRQLV NSLSKYVASP YDGQRVAAVG IFSRLVPLKP
1460 1470 1480 1490 1500
TGELAASILL HLGAALSDPN AVVRGLSIQG MGYVGQLGEK EAKRYSETAI
1510 1520 1530 1540 1550
GALLKGVDDP VGDCLINIPL ESMRGLSGIL RALPSERVEP FHVSLAIRIR
1560 1570 1580 1590 1600
PFLGNYALEM REAAIQLFGD ICEGKHDDGS SSPTSSMEAL REQLIANLFP
1610 1620 1630 1640 1650
LLLHLSESEV AIASACRGTL QRVCRLLTAP RVVEMAEQQL GEERGHQLNY
1660 1670 1680 1690 1700
SSFVLEFVKT IALELTDHIQ DFIDSCLPQL RSQWPEVRGS AAIVIGILHN
1710 1720 1730 1740
FLSERNVQTE TVASKIAVLL KDEQALVRMR AATALGYFFG DI
Length:1,742
Mass (Da):193,091
Last modified:March 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE2539654B9F6E282
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46485.2
AY069558 mRNA Translation: AAL39703.1
AE014298 Genomic DNA Translation: AHN59521.1

NCBI Reference Sequences

More...
RefSeqi
NP_001285050.1, NM_001298121.1
NP_652606.1, NM_144349.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0071326; FBpp0071261; FBgn0040236
FBtr0343368; FBpp0310025; FBgn0040236

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
53436

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG12132

UCSC genome browser

More...
UCSCi
CG12132-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46485.2
AY069558 mRNA Translation: AAL39703.1
AE014298 Genomic DNA Translation: AHN59521.1
RefSeqiNP_001285050.1, NM_001298121.1
NP_652606.1, NM_144349.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9W350, 2 interactors
STRINGi7227.FBpp0071261

Proteomic databases

PRIDEiQ9W350

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
53436

Genome annotation databases

EnsemblMetazoaiFBtr0071326; FBpp0071261; FBgn0040236
FBtr0343368; FBpp0310025; FBgn0040236
GeneIDi53436
KEGGidme:Dmel_CG12132
UCSCiCG12132-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
53436
FlyBaseiFBgn0040236, c11.1
VEuPathDBiVectorBase:FBgn0040236

Phylogenomic databases

eggNOGiKOG2032, Eukaryota
GeneTreeiENSGT00940000166577
HOGENOMiCLU_003168_0_1_1
OMAiNMVSFHN
OrthoDBi31329at2759
PhylomeDBiQ9W350

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
53436, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
53436

Gene expression databases

BgeeiFBgn0040236, Expressed in Malpighian tubule and 39 other tissues
ExpressionAtlasiQ9W350, baseline and differential

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
SUPFAMiSSF48371, SSF48371, 3 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9W350_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W350
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: March 1, 2001
Last modified: September 29, 2021
This is version 169 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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