Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 164 (29 Sep 2021)
Sequence version 4 (04 Dec 2007)
Previous versions | rss
Add a publicationFeedback
Protein

Palmitoyltransferase ZDHHC8

Gene

Zdhhc8

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes (By similarity).

Regulates tissue growth possibly by regulating Ras64B protein stability (PubMed:30735487).

May regulate CG34450 mRNA levels (PubMed:30735487).

By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei129S-palmitoyl cysteine intermediatePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Palmitoyltransferase ZDHHC8Curated (EC:2.3.1.225By similarity)
Alternative name(s):
Zinc finger DHHC domain-containing protein 8By similarity
Zinc finger DHHC-type containing 81 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zdhhc81 PublicationImported
Synonyms:anon-Pen16Imported, Dm_X:47283Imported, p16Imported
ORF Names:CG34449Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0085478, Zdhhc8

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:FBgn0085478

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 9CytoplasmicCurated9
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei10 – 30HelicalSequence analysisAdd BLAST21
Topological domaini31 – 47ExtracellularCuratedAdd BLAST17
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Topological domaini69 – 142CytoplasmicCuratedAdd BLAST74
Transmembranei143 – 163HelicalSequence analysisAdd BLAST21
Topological domaini164 – 177ExtracellularCuratedAdd BLAST14
Transmembranei178 – 198HelicalSequence analysisAdd BLAST21
Topological domaini199 – 934CytoplasmicCuratedAdd BLAST736

Keywords - Cellular componenti

Cell membrane, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Lethal at larval stage (PubMed:30735487). RNAi-mediated knockdown results in extra vein material (PubMed:30735487). RNAi-mediated knockdown in the wing results in tissue overgrowth due to enhanced cell proliferation (PubMed:30735487).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004535251 – 934Palmitoyltransferase ZDHHC8CuratedAdd BLAST934

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9W345

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0085478, Expressed in digestive system element and 33 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9W345, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9W345, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9W345, 8 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0111665

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9W345

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini99 – 149DHHCPROSITE-ProRule annotationAdd BLAST51

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni336 – 440DisorderedSequence analysisAdd BLAST105
Regioni506 – 525DisorderedSequence analysisAdd BLAST20
Regioni669 – 705DisorderedSequence analysisAdd BLAST37
Regioni751 – 780DisorderedSequence analysisAdd BLAST30
Regioni835 – 862DisorderedSequence analysisAdd BLAST28
Regioni881 – 934DisorderedSequence analysisAdd BLAST54

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi336 – 353Polar residuesSequence analysisAdd BLAST18
Compositional biasi363 – 406Polar residuesSequence analysisAdd BLAST44
Compositional biasi678 – 705Polar residuesSequence analysisAdd BLAST28
Compositional biasi840 – 860Polar residuesSequence analysisAdd BLAST21
Compositional biasi881 – 923Polar residuesSequence analysisAdd BLAST43

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The DHHC domain is required for palmitoyltransferase activity.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1311, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000175425

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010307_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9W345

Identification of Orthologs from Complete Genome Data

More...
OMAi
YPWVPAY

Database of Orthologous Groups

More...
OrthoDBi
1264614at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9W345

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001594, Palmitoyltrfase_DHHC

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01529, DHHC, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50216, DHHC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (6+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 6 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 6 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform AImported (identifier: Q9W345-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPKCDVKTRY IPATFAWIVL LLTTFLFFFY PCQFYVKSHP WVLAYQGVIT
60 70 80 90 100
FFVLANFTLA TFMDPGIIPK ASPDEDCEEE LRAPLYKNAE INGITVKMKW
110 120 130 140 150
CVTCKFYRPP RCSHCSVCNH CIETFDHHCP WVNNCIGRRN YRFFFFFLVS
160 170 180 190 200
LSIHMLSIFS LCLVYVLKIM PNIKDTAPIV AIILMGLVTI LAIPIFGLTG
210 220 230 240 250
FHMVLVSRGR TTNEQVTGKF KGGYNPFSRG CWHNCCYTQF GPQYPSLLNP
260 270 280 290 300
KKYASRRSQV QNQAISTICN DRSGQQTGAG SGAGGNGTAA VSGGGGGVGS
310 320 330 340 350
GGGMRGTAVQ YSPRSFYDAS REKRGIQVKT YMAEGNGYNQ RSGSTTLYSK
360 370 380 390 400
LSPGRECSDT DLEPPPASQS QDCEPTPPLQ RHNSSSFYLP QVSDSGGLNG
410 420 430 440 450
SVSTGGGGGG DSPRHMRLYH PRHSPHARPR GLDPQRGYTS DALSPDHPVG
460 470 480 490 500
YGVGVNGSQQ QQQQALAAAA AAAAVAAQNQ RSATTTATPT MQQRIKPLGV
510 520 530 540 550
ATPLVMASPV RRSNPGTPTQ PRRPDFIGLN AQAVAQQQQQ QQQAAAAAAA
560 570 580 590 600
AYYEYTSGLP PQHPQAPSIQ QQQQQLLLQQ QRVLMQHQQQ QQALQQQQQQ
610 620 630 640 650
QQQAAVHAAH PQHAALAQAA YGGSPQRRFL SEGELVRQGA GGGVAGGELS
660 670 680 690 700
YARSNNTVDN IRELAGSPQR GVYMWKDTSP GFTNNAGQQQ QQQQQAQQVV
710 720 730 740 750
SSGIGSSAGT LSSSGAAAGV MPHAQYMTAG GGAHPLIMTH SRLQDYTIQQ
760 770 780 790 800
QQQQQQQQAA AAAAASYHRS NPTSPTTMPQ VSGAGQSYIL RYGGGGAVGA
810 820 830 840 850
AGSSGSLASV TASNPATGGG GYQPALRGGV AVFPPNPMGN QGGGNLQTQP
860 870 880 890 900
SPQIKRKQTP TRPMSFVRAL EMADSMEMQS LEQQQNGGIP GSGSVGNNQQ
910 920 930
AGGGGGGHLM QSNASNSGTP DRASIYDMNY EISV
Length:934
Mass (Da):99,717
Last modified:December 4, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8772DDF71B7EE7E3
GO
Isoform BImported (identifier: Q9W345-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     328-350: Missing.

Show »
Length:911
Mass (Da):97,179
Checksum:iDCCA3236C61E2F85
GO
Isoform CImported (identifier: Q9W345-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     328-350: Missing.
     512-523: RSNPGTPTQPRR → SQYSNSENSTNS
     524-934: Missing.

Show »
Length:500
Mass (Da):54,397
Checksum:i42AA0A1A6F2C3B4E
GO
Isoform DImported (identifier: Q9W345-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     512-523: RSNPGTPTQPRR → SQYSNSENSTNS
     524-934: Missing.

Show »
Length:523
Mass (Da):56,935
Checksum:i95301D36C4AB3EAB
GO
Isoform FImported (identifier: Q9W345-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     430-511: Missing.

Show »
Length:852
Mass (Da):91,366
Checksum:iF652F5DAF6729C39
GO
Isoform GImported (identifier: Q9W345-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     71-75: Missing.
     328-350: Missing.

Show »
Length:906
Mass (Da):96,679
Checksum:i8965033B662B221A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PH36M9PH36_DROME
Zinc finger DHHC-type containing 8,...
Zdhhc8 anon-Pen16, CG12136, CG15372, CG17251, CG32705
1,052Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_06115871 – 75Missing in isoform G. Curated5
Alternative sequenceiVSP_061159328 – 350Missing in isoform B, isoform G and isoform C. CuratedAdd BLAST23
Alternative sequenceiVSP_061160430 – 511Missing in isoform F. CuratedAdd BLAST82
Alternative sequenceiVSP_061161512 – 523RSNPG…TQPRR → SQYSNSENSTNS in isoform D and isoform C. CuratedAdd BLAST12
Alternative sequenceiVSP_061162524 – 934Missing in isoform D and isoform C. CuratedAdd BLAST411

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46491.4
AE014298 Genomic DNA Translation: AFH07306.1
AE014298 Genomic DNA Translation: ABW09368.1
AE014298 Genomic DNA Translation: ABW09369.1
AE014298 Genomic DNA Translation: AHN59522.1
AE014298 Genomic DNA Translation: AHN59523.1

NCBI Reference Sequences

More...
RefSeqi
NP_727339.3, NM_167189.6

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0112753; FBpp0111665; FBgn0085478

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
31887

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG34449

UCSC genome browser

More...
UCSCi
CG34449-RA, d. melanogaster

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF46491.4
AE014298 Genomic DNA Translation: AFH07306.1
AE014298 Genomic DNA Translation: ABW09368.1
AE014298 Genomic DNA Translation: ABW09369.1
AE014298 Genomic DNA Translation: AHN59522.1
AE014298 Genomic DNA Translation: AHN59523.1
RefSeqiNP_727339.3, NM_167189.6

3D structure databases

SMRiQ9W345
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9W345, 8 interactors
STRINGi7227.FBpp0111665

Proteomic databases

PRIDEiQ9W345

Genome annotation databases

EnsemblMetazoaiFBtr0112753; FBpp0111665; FBgn0085478
GeneIDi31887
KEGGidme:Dmel_CG34449
UCSCiCG34449-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
29801
FlyBaseiFBgn0085478, Zdhhc8
VEuPathDBiVectorBase:FBgn0085478

Phylogenomic databases

eggNOGiKOG1311, Eukaryota
GeneTreeiENSGT00940000175425
HOGENOMiCLU_010307_0_0_1
InParanoidiQ9W345
OMAiYPWVPAY
OrthoDBi1264614at2759
PhylomeDBiQ9W345

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
31887, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
31887

Gene expression databases

BgeeiFBgn0085478, Expressed in digestive system element and 33 other tissues
ExpressionAtlasiQ9W345, baseline and differential
GenevisibleiQ9W345, DM

Family and domain databases

InterProiView protein in InterPro
IPR001594, Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529, DHHC, 1 hit
PROSITEiView protein in PROSITE
PS50216, DHHC, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZDHC8_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W345
Secondary accession number(s): A8JUM2
, A8JUM5, M9NGX0, X2JE99, X2JJ56
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 29, 2021
Last sequence update: December 4, 2007
Last modified: September 29, 2021
This is version 164 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again