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Entry version 150 (03 Jul 2019)
Sequence version 3 (05 Jul 2004)
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Protein
Submitted name:

Uncharacterized protein, isoform B

Gene

Dmel\CG9485

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidaseImported, GlycosyltransferaseImported, Hydrolase, Transferase

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-6798695 Neutrophil degranulation

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GH13 Glycoside Hydrolase Family 13
GH133 Glycoside Hydrolase Family 133

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein, isoform BImported (EC:2.4.1.25Imported, EC:3.2.1.33Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dmel\CG9485Imported
Synonyms:BEST:GH22856Imported, FBgn0034618Imported
ORF Names:CG9485Imported, Dmel_CG9485Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0034618 CG9485

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9W2H8

PRoteomics IDEntifications database

More...
PRIDEi
Q9W2H8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0034618 Expressed in 14 organ(s), highest expression level in head

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9W2H8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9W2H8 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0071526

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini121 – 224hGDE_NInterPro annotationAdd BLAST104
Domaini230 – 672hDGE_amylaseInterPro annotationAdd BLAST443
Domaini810 – 1080hGDE_centralInterPro annotationAdd BLAST271
Domaini1148 – 1616GDE_CInterPro annotationAdd BLAST469

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3625 Eukaryota
COG3408 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012596

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9W2H8

Database of Orthologous Groups

More...
OrthoDBi
33175at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9W2H8

Family and domain databases

Conserved Domains Database

More...
CDDi
cd11327 AmyAc_Glg_debranch_2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR010401 AGL/Gdb1
IPR032788 AGL_central
IPR029436 AGL_euk_N
IPR032792 AGL_glucanoTrfase
IPR032790 GDE_C
IPR006421 Glycogen_debranch_met
IPR017853 Glycoside_hydrolase_SF

The PANTHER Classification System

More...
PANTHERi
PTHR10569 PTHR10569, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06202 GDE_C, 1 hit
PF14701 hDGE_amylase, 1 hit
PF14702 hGDE_central, 1 hit
PF14699 hGDE_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48208 SSF48208, 1 hit
SSF51445 SSF51445, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01531 glyc_debranch, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9W2H8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRYQLFRWLY GLIATVDNEP LPLQIKSEEE AFGENKKKKQ LASLENAISP
60 70 80 90 100
GKLDSVAIRT VPSANANAMG NAGSAEIVSN QIIRRREMST MGKETESHSI
110 120 130 140 150
PISEGQDAEH ILYRLKRGSK LSVHPDASLL GRKIVLYTNY PAEGQKFVRT
160 170 180 190 200
EYRVLGWQLS NGKQITSVMH PEAHVVDTDI RSQVELNMSG TYHFYFRYLE
210 220 230 240 250
RPDTGCSGAD GALYVQVEPT LHVGPPGAQK TIPLDSVRCQ TVLAKLLGPL
260 270 280 290 300
DTWEPKLRVA KEAGYNVIHF TPIQELGGSR SCYSLRDQLK VNSHFAPQKG
310 320 330 340 350
GKISFEDVEK VIKKCRQEWG VASICDIVLN HTANESDWLL QHPDATYSCA
360 370 380 390 400
TCPYLRPAFL LDATFAQCGA DIAEGSLEHV GVPAVIEQEC HLEALKYQLH
410 420 430 440 450
TSYMSKVNIH ELYQCDVMKY VNEFMSQVRT REPPKNVANE CRFQEIQLIQ
460 470 480 490 500
DPQYRRLAST INFELALEIF NAFHGDCFDE ESRFRKCAET LRRHLDALND
510 520 530 540 550
RVRCEVQGYI NYAIDNVLAG VRYERVQGDG PRVKEISEKH SVFMVYFTHT
560 570 580 590 600
GTQGKSLTEI EADMYTKAGE FFMAHNGWVM GYSDPLRDFA EEQPGRANVY
610 620 630 640 650
LKRELISWGD SVKLRFGRRP EDSPYLWQHM TEYVQTTARI FDGVRLDNCH
660 670 680 690 700
STPLHVAEYL LDAARKINPE LYVVAELFTN SDYTDNVFVN RLGITSLIRE
710 720 730 740 750
ALSAWDSHEQ GRLVYRYGGV PVGGFQANSS RHEATSVAHA LFLDLTHDNP
760 770 780 790 800
SPVEKRSVYD LLPSAALVSM ACCATGSNRG YDELVPHHIH VVDEERTYQE
810 820 830 840 850
WGKGVDSKSG IMGAKRALNL LHGQLAEEGF SQVYVDQMDP NVVAVTRHSP
860 870 880 890 900
ITHQSVILVA HTAFGYPSPN AGPTGIRPLR FEGVLDEIIL EASLTMQSDK
910 920 930 940 950
PFDRPAPFKK DPNVINGFTQ FQLNLQEHIP LAKSTVFQTQ AYSDGNNTEL
960 970 980 990 1000
NFANLRPGTV VAIRVSMHPG PRTSFDKLQK ISAALRIGSG EEYSQLQAIV
1010 1020 1030 1040 1050
SKLDLVALSG ALFSCDDEER DLGKGGTAYD IPNFGKIVYC GLQGFISLLT
1060 1070 1080 1090 1100
EISPKNDLGH PLCNNLRDGN WMMDYISDRL TSYEDLKPLS AWFKATFEPL
1110 1120 1130 1140 1150
KNIPRYLIPC YFDAIVSGVY NVLINQVNEL MPDFIKNGHS FPQSLALSTL
1160 1170 1180 1190 1200
QFLSVCKSAN LPGFSPALSP PKPPKQCVTL SAGLPHFSTG YMRCWGRDTF
1210 1220 1230 1240 1250
IALRGSMFLT GRYNEARFII IGFGQTLRHG LIPNLLDSGS KPRFNCRDAI
1260 1270 1280 1290 1300
WWWMYCIKQY VEDAPKGAEI LKDKVSRIFP YDDADAHAPG AFDQLLFDVM
1310 1320 1330 1340 1350
QEALQVHFQG LQYRERNAGY EIDAHMVDQG FNNQIGIHPE TGFVFGGNNF
1360 1370 1380 1390 1400
NCGTWMDKMG SSQKAGNKGR PSTPRDGSAV ELVGLQYAVL RFMQSLAEKE
1410 1420 1430 1440 1450
VIPYTGVERK GPSGEVTKWS YKEWADRIKN NFDKYFFVSE SETCSVANKK
1460 1470 1480 1490 1500
LIYKDSYGAT QSWTDYQLRC NFPITLTVAP DLCNPQNAWR ALERAKKYLL
1510 1520 1530 1540 1550
GPLGMKTMDP EDWNYRANYD NSNDSTDCTV AHGANYHQGP EWVWPIGFYL
1560 1570 1580 1590 1600
RARLIFAKKC GHLDETIAET WAILRAHLRE LQTSHWRGLP ELTNDNGSYC
1610 1620
GDSCRTQAWS VAAILEVLYD LHSLGADVA
Length:1,629
Mass (Da):183,219
Last modified:July 5, 2004 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i06020245A3AF4929
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E1JGQ5E1JGQ5_DROME
Uncharacterized protein, isoform D
FBgn0034618 BEST:GH22856, Dmel\CG9485, CG9485, Dmel_CG9485
1,563Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q86BS7Q86BS7_DROME
Uncharacterized protein, isoform C
BEST:GH22856 Dmel\CG9485, FBgn0034618, CG9485, Dmel_CG9485
1,546Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q7KVP4Q7KVP4_DROME
Uncharacterized protein, isoform A
Dmel\CG9485 BEST:GH22856, FBgn0034618, CG9485, Dmel_CG9485
1,542Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAM70868.2

NCBI Reference Sequences

More...
RefSeqi
NP_726062.2, NM_166444.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0071600; FBpp0071526; FBgn0034618

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
37435

UCSC genome browser

More...
UCSCi
CG9485-RB d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAM70868.2
RefSeqiNP_726062.2, NM_166444.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7227.FBpp0071526

Protein family/group databases

CAZyiGH13 Glycoside Hydrolase Family 13
GH133 Glycoside Hydrolase Family 133

Proteomic databases

PaxDbiQ9W2H8
PRIDEiQ9W2H8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0071600; FBpp0071526; FBgn0034618
GeneIDi37435
UCSCiCG9485-RB d. melanogaster

Organism-specific databases

FlyBaseiFBgn0034618 CG9485

Phylogenomic databases

eggNOGiKOG3625 Eukaryota
COG3408 LUCA
GeneTreeiENSGT00390000012596
InParanoidiQ9W2H8
OrthoDBi33175at2759
PhylomeDBiQ9W2H8

Enzyme and pathway databases

ReactomeiR-DME-6798695 Neutrophil degranulation

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
37435

Gene expression databases

BgeeiFBgn0034618 Expressed in 14 organ(s), highest expression level in head
ExpressionAtlasiQ9W2H8 baseline and differential
GenevisibleiQ9W2H8 DM

Family and domain databases

CDDicd11327 AmyAc_Glg_debranch_2, 1 hit
Gene3Di1.50.10.10, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR010401 AGL/Gdb1
IPR032788 AGL_central
IPR029436 AGL_euk_N
IPR032792 AGL_glucanoTrfase
IPR032790 GDE_C
IPR006421 Glycogen_debranch_met
IPR017853 Glycoside_hydrolase_SF
PANTHERiPTHR10569 PTHR10569, 1 hit
PfamiView protein in Pfam
PF06202 GDE_C, 1 hit
PF14701 hDGE_amylase, 1 hit
PF14702 hGDE_central, 1 hit
PF14699 hGDE_N, 1 hit
SUPFAMiSSF48208 SSF48208, 1 hit
SSF51445 SSF51445, 1 hit
TIGRFAMsiTIGR01531 glyc_debranch, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9W2H8_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W2H8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: July 5, 2004
Last modified: July 3, 2019
This is version 150 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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