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Entry version 144 (02 Jun 2021)
Sequence version 2 (01 Oct 2002)
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Protein

Protein mahjong

Gene

mahj

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable substrate recognition component of tsome E3 ubiquitin-protein ligase complex (By similarity).

Plays a key role in cell competition via its interaction with l2gl.

By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathway

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-983168, Antigen processing: Ubiquitination & Proteasome degradation

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein mahjong
Alternative name(s):
DDB1- and CUL4-associated factor-like 1
VPRBP-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mahj
ORF Names:CG10080
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0034641, mahj

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Homozygous mutants develop more slowly and die at a late pupal stage. Zygotic mutants do not have obvious patterning defects during embryonic or larval development but cells undergo apoptosis when surrounded by wild-type cells in the wing disk epithelium.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002874761 – 1544Protein mahjongAdd BLAST1544

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei565Phosphoserine1 Publication1
Modified residuei569Phosphoserine1 Publication1
Modified residuei955Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9W2F2

PRoteomics IDEntifications database

More...
PRIDEi
Q9W2F2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9W2F2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0034641, Expressed in oocyte and 36 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9W2F2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9W2F2, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the CUL4-RBX1-DDB1-DCAF1 E3 ubiquitin-protein ligase complex (By similarity).

Interacts with l2gl.

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
63088, 15 interactors

Protein interaction database and analysis system

More...
IntActi
Q9W2F2, 2 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0293270

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9W2F2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini912 – 944LisHPROSITE-ProRule annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 110DisorderedSequence analysisAdd BLAST110
Regioni946 – 973DisorderedSequence analysisAdd BLAST28
Regioni987 – 1059DisorderedSequence analysisAdd BLAST73
Regioni1447 – 1475DisorderedSequence analysisAdd BLAST29
Regioni1487 – 1544DisorderedSequence analysisAdd BLAST58

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1302 – 1309DWD box 18
Motifi1338 – 1345DWD box 28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi40 – 86Acidic residuesSequence analysisAdd BLAST47
Compositional biasi1012 – 1032Polar residuesSequence analysisAdd BLAST21
Compositional biasi1454 – 1468Acidic residuesSequence analysisAdd BLAST15
Compositional biasi1496 – 1533Acidic residuesSequence analysisAdd BLAST38

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The DWD boxes are required for interaction with DDB1.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the VPRBP/DCAF1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1832, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005874

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001785_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9W2F2

Identification of Orthologs from Complete Genome Data

More...
OMAi
VWESVCS

Database of Orthologous Groups

More...
OrthoDBi
105679at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9W2F2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR006594, LisH
IPR033270, VPRBP/DCAF1
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR036322, WD40_repeat_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13129, PTHR13129, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00667, LisH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50896, LISH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9W2F2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEGSGSENA AAAEAAAEAE AATEAALMAE AVAVAYQSDE EEQPEAEDMP
60 70 80 90 100
EQAGDNQEED AAEQQDGGEP EADEDADADD AMSVENAENE SDSGGNAEET
110 120 130 140 150
AAADRRQATK KELTQIIDKW EQQQTQNGYD PVPTLRSLAE IFEREKDVYR
160 170 180 190 200
RKDPDPLDSR HPYRADPSCQ YGLLLKLLFR KDTFMGKLLN DYLRENYFSR
210 220 230 240 250
QNVSRSSLEL NILACRLILE IMPGMETSAV FQTAEGDGTI NRIYSWAEDS
260 270 280 290 300
IEPLQSYATG LLAEAMEVSD IAINFRDLNI RLVPKMIKRL HMLLAISKSA
310 320 330 340 350
TSDVNTSMHN LSADSSTAGM LSWVACASNA SAPQSPQHNG SGLGASSSQH
360 370 380 390 400
GDASNMSILF ENSRDAFSVS RYYKRMYIPL HPATADTSQM LIMRFLTSLG
410 420 430 440 450
EYQEFLAMAF ENNVMQLIFG YLENLDRRDT CLAYEVLKYL ASLLCHKKFA
460 470 480 490 500
LEFISHGGLE LLLKVPRPSL ATTGVSIAIY YLAYCEDAME RICSMQRPLI
510 520 530 540 550
SELVRYALWI LGRCHDSSKC HATMFFSLSF QFKVILDEFD AQDGLRKLYN
560 570 580 590 600
VISVLKILDP SHNDSDNDSD FNEDVECASR QMVRHVCVAL KRYMEAHFFY
610 620 630 640 650
KYNSFLCQTN AASPAPSSAH YFNQNPTVAA KLTFDQLNDQ IRTLQEHTSI
660 670 680 690 700
RAHWQPVDQL MKLGGITMLL RIIAFSYDWV NSGRSETVRS ALDVLSVCCI
710 720 730 740 750
IPRVYVVLCE RLLMLDKTTT SGFCSVLGAA AGEISSDAEV IKSALAVLCH
760 770 780 790 800
CVCSPIIRKD SGTSLIKFGT SSRKNKANHK YAEELIERVW ESVCSNNGIV
810 820 830 840 850
VLLSLMQTKG PITDADCIRG MACRALAGLA RSDRVRQIVS KLPLFASGQL
860 870 880 890 900
QTLMRDPILQ EKRAEHVIFQ KYALELLERV SGKTKPLNNP LDPSLSNMHK
910 920 930 940 950
ANVIAQTRIQ YNKQQLYQLI FEHLESNGLS QTAQMLQREV GLPLQTPTTR
960 970 980 990 1000
SFHQSPFDYK SLPSGSSSLS RNRLRSRMQD VNAAIMGNGD LNRSFGEDSS
1010 1020 1030 1040 1050
PAGAGGSNAG DGVSIPNFSS LNTTQTPIKI RRTDRSSVSR SIQKQAMEPG
1060 1070 1080 1090 1100
GMSVGLAEDG QLHPKRITLN TIVTEYLTNQ HSLCNNPVTT CPQFDLYEPH
1110 1120 1130 1140 1150
KCPDPKPSRL LSSNYNLTSR HARTQAGFNT SRFDRRYVHT HFSPWRSIRS
1160 1170 1180 1190 1200
ADYEDLEFTC CDLAGKYIIV GTQQGDGRVF NMNDGVEQFF SNCHNFSVDA
1210 1220 1230 1240 1250
IKANRAGDLV ITSSFWRTPT SILWSIADDE FKLKLRLPDV TYCEFSQTVQ
1260 1270 1280 1290 1300
DRLLGTQNEC ATLFDINTGS KVASFTPTIP NLYTKNRATL CRTDELILSD
1310 1320 1330 1340 1350
GVLWDVRSGK EIHKFDKFNQ CISGVFHPNC LEIIANTEVW DLRTFHLLQT
1360 1370 1380 1390 1400
VPVLDQRNCT FSPMHVIYGA SLGADRDHDM ETTTYDTSFN VLDAYDYSSI
1410 1420 1430 1440 1450
ATIDVKRNIN DLSVSANGSL IAVVEDYSGY ESKQETYVKI YAVGVKKSER
1460 1470 1480 1490 1500
SEEEDDEEVP ESDEDGSDTG SENTFAIGQN LLGFPLLRNL HGSDNDDEDL
1510 1520 1530 1540
DEDDDDGEPL DSDDDSDDDD GSDNGDDDGD FDVLEYFDRS SSDD
Length:1,544
Mass (Da):172,085
Last modified:October 1, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF70B699513C3DAD5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4K8A5A0A0B4K8A5_DROME
Mahjong, isoform B
mahj anon-WO0172774.151, BcDNA:SD08722, Dmel\CG10080, Mahj, VprBP
1,544Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAO24927 differs from that shown. Reason: Frameshift.Curated
The sequence AAV36910 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti48 – 49DM → ET in AAO24927 (Ref. 3) Curated2
Sequence conflicti1376R → K in AAO24927 (Ref. 3) Curated1
Sequence conflicti1376R → K in AAM48473 (Ref. 3) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF46740.2
AY118444 mRNA Translation: AAM48473.2
BT003172 mRNA Translation: AAO24927.1 Frameshift.
BT016025 mRNA Translation: AAV36910.1 Frameshift.

NCBI Reference Sequences

More...
RefSeqi
NP_001246451.1, NM_001259522.2
NP_611592.2, NM_137748.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0071658; FBpp0071575; FBgn0034641
FBtr0304728; FBpp0293270; FBgn0034641

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
37462

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG10080

UCSC genome browser

More...
UCSCi
CG10080-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF46740.2
AY118444 mRNA Translation: AAM48473.2
BT003172 mRNA Translation: AAO24927.1 Frameshift.
BT016025 mRNA Translation: AAV36910.1 Frameshift.
RefSeqiNP_001246451.1, NM_001259522.2
NP_611592.2, NM_137748.4

3D structure databases

SMRiQ9W2F2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi63088, 15 interactors
IntActiQ9W2F2, 2 interactors
STRINGi7227.FBpp0293270

PTM databases

iPTMnetiQ9W2F2

Proteomic databases

PaxDbiQ9W2F2
PRIDEiQ9W2F2

Genome annotation databases

EnsemblMetazoaiFBtr0071658; FBpp0071575; FBgn0034641
FBtr0304728; FBpp0293270; FBgn0034641
GeneIDi37462
KEGGidme:Dmel_CG10080
UCSCiCG10080-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
37462
FlyBaseiFBgn0034641, mahj

Phylogenomic databases

eggNOGiKOG1832, Eukaryota
GeneTreeiENSGT00390000005874
HOGENOMiCLU_001785_1_0_1
InParanoidiQ9W2F2
OMAiVWESVCS
OrthoDBi105679at2759
PhylomeDBiQ9W2F2

Enzyme and pathway databases

UniPathwayiUPA00143
ReactomeiR-DME-983168, Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
37462, 1 hit in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
37462

Protein Ontology

More...
PROi
PR:Q9W2F2

Gene expression databases

BgeeiFBgn0034641, Expressed in oocyte and 36 other tissues
ExpressionAtlasiQ9W2F2, baseline and differential
GenevisibleiQ9W2F2, DM

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR006594, LisH
IPR033270, VPRBP/DCAF1
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR036322, WD40_repeat_dom_sf
PANTHERiPTHR13129, PTHR13129, 1 hit
SMARTiView protein in SMART
SM00667, LisH, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
SSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50896, LISH, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDCAF1_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W2F2
Secondary accession number(s): Q5U167, Q86PE6, Q8MT13
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 1, 2002
Last modified: June 2, 2021
This is version 144 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families
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