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UniProtKB - Q9W1X5 (Q9W1X5_DROME)
Protein
Submitted name:
GH04942p
Gene
nahoda
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
Names & Taxonomyi
Protein namesi | Submitted name: GH04942pImportedSubmitted name: Nahoda, isoform AImportedSubmitted name: Nahoda, isoform BImported |
Gene namesi | ORF Names:CG12781Imported, Dmel_CG12781Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0034797, nahoda |
VEuPathDBi | VectorBase:FBgn0034797 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 1088 – 1111 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembranePTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 229 ↔ 238 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondPROSITE-ProRule annotationExpressioni
Gene expression databases
Bgeei | FBgn0034797, Expressed in second segment of antenna (Drosophila) and 39 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q9W1X5, 4 interactors |
STRINGi | 7227.FBpp0071853 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 198 – 239 | EGF-likeInterPro annotationAdd BLAST | 42 | |
Domaini | 549 – 680 | DOMONInterPro annotationAdd BLAST | 132 | |
Domaini | 767 – 887 | DOMONInterPro annotationAdd BLAST | 121 | |
Domaini | 933 – 1046 | SEAInterPro annotationAdd BLAST | 114 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 319 – 590 | DisorderedSequence analysisAdd BLAST | 272 | |
Regioni | 1147 – 1322 | DisorderedSequence analysisAdd BLAST | 176 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 324 – 426 | Basic and acidic residuesSequence analysisAdd BLAST | 103 | |
Compositional biasi | 438 – 551 | Basic and acidic residuesSequence analysisAdd BLAST | 114 | |
Compositional biasi | 1167 – 1223 | Polar residuesSequence analysisAdd BLAST | 57 | |
Compositional biasi | 1237 – 1252 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 1260 – 1302 | Basic and acidic residuesSequence analysisAdd BLAST | 43 |
Keywords - Domaini
EGF-like domainPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG4293, Eukaryota |
GeneTreei | ENSGT00610000087018 |
HOGENOMi | CLU_269388_0_0_1 |
OMAi | LIQNSPW |
OrthoDBi | 1064366at2759 |
Family and domain databases
CDDi | cd09631, DOMON_DOH, 2 hits |
InterProi | View protein in InterPro IPR045266, DOH_DOMON IPR005018, DOMON_domain IPR000742, EGF-like_dom IPR013111, EGF_extracell IPR000082, SEA_dom |
Pfami | View protein in Pfam PF07974, EGF_2, 1 hit |
SMARTi | View protein in SMART SM00664, DoH, 2 hits |
PROSITEi | View protein in PROSITE PS50836, DOMON, 2 hits PS00022, EGF_1, 1 hit PS01186, EGF_2, 1 hit PS50026, EGF_3, 1 hit PS50024, SEA, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9W1X5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSIQSTRHSP FAWTARALLL LATWCCYLGY LGSEAHVALT YPPARKFDLD
60 70 80 90 100
FLDNARTKAP CGMPKGSIRT SLLSGTQFNV TWHLAYAHKG GFRLQLLDAL
110 120 130 140 150
DRPVLDLTPH VNNSEFVSTD VTAQSYQVKI PNDFECYNCT LRLLRQADEW
160 170 180 190 200
TTSYRFWSCA DVDIKLRKDF KETCSGNGKY FPSRCKCDKN FYGPQCQYKD
210 220 230 240 250
ECSADSDCGV QGKCVELGGT SLPKKQCYCN FGWFGIGCNK RSPYKSTSLD
260 270 280 290 300
LSSYSKKELS PDYHVYWRLL EEQKEIEMVL KVNGTSWVGL GWRPRGMTPE
310 320 330 340 350
CKNFPLIRDI GDLTTTLEAS VPEPKSEPEP KSEPEPKSEP EPKSEPEPKS
360 370 380 390 400
EPEPKSEPEP KSEPEPKSEP EPKSEPEPKS EPEPKSEPEP KSEPEPKSEP
410 420 430 440 450
EPKSEPEPKS EPEPKSEPEP KSEPQPKQLA ELRAAPEPQS EPEPKSEPEP
460 470 480 490 500
KSEPEPKSEP EPKSEPEPKS EPEPKSEPEP KSEPEPKSEP EPTSEPEPKS
510 520 530 540 550
APEPKSEPEP TSEPEPTSKP EPTSEPEPKS EPEPKSEPEA QSSKSKRVAG
560 570 580 590 600
DFAKKGVSSV STSVSYRVST KSDRQRREAD SPKYRLNPYT PRHDFNGMDC
610 620 630 640 650
TDIVIGAARG MASRVGDYYS RDRSTPHTDE FFGGKSNLAL GTGFEENGVT
660 670 680 690 700
TIIFRKKLVA NEPTDHTLDD ALTHVIWAKG QEPEAYVHVP ASGLETQIAT
710 720 730 740 750
VKNFYQQDEL KYHGHQMQRG VTQINFFEKE KSATSTDRND LGTNVLDNDC
760 770 780 790 800
YGHWKYPSNC SPQEHTCEYY ASWETVGKGD EMRWHIETSN TQTWTGIGFS
810 820 830 840 850
DDQRMSQTDA IIGWVDGRSG RPFLMDTWVL GYAPPKLDDR QDIYNASGRI
860 870 880 890 900
EKGVTILEFN RKRVSNDEQD LSFTDDHCLY LFFPVLGGAF NVVNKKIRKH
910 920 930 940 950
EQVPPISSQR VCIKSCGKEL ESVFVGTSTP APSRLVYAVA VKLMNLGESY
960 970 980 990 1000
EAPKPGTVEF NNLAATISDS FNGILSPLTG YYKTEILGFE KEGSTMVAKV
1010 1020 1030 1040 1050
QAMFDKADVE KKHALETNEV DKTSEAAAQK NADVIRSALK DQVATGRVGS
1060 1070 1080 1090 1100
LTVDPQFLDF EALEYKSSSE PNAKETLLSF FDLSETRLYI VLGLIAALVL
1110 1120 1130 1140 1150
IALIQAFCTI WKTSRKSKNT KEKLIQNSPW KEFASNTNYA FDPYGETEEK
1160 1170 1180 1190 1200
NITNSSSGKE KARNRHQSTT SSQQTTLPMS HSPTSKSQMY YESPNGQGKS
1210 1220 1230 1240 1250
SNGNGSRGNG RATQESSVGG APYSRSSYAE RAYSLPRQAH QYQQSPASMQ
1260 1270 1280 1290 1300
PSGYYTHDRR AARQGSRDRE REREREEERR QRQDRDRDSG YDRSRDDPRQ
1310 1320 1330
NGGSDTPDFY FMPSQRKYSG EVVRVYVDYN KDPKH
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0B4K7Z1 | A0A0B4K7Z1_DROME | Nahoda, isoform C | nahoda CT36793, Dmel\CG12781, CG12781, Dmel_CG12781 | 1,148 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013599 Genomic DNA Translation: AAF46927.2 AY060632 mRNA Translation: AAL28180.1 AE013599 Genomic DNA Translation: AAN16114.1 |
RefSeqi | NP_523815.2, NM_079091.4 NP_726264.1, NM_166569.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0071942; FBpp0071853; FBgn0034797 FBtr0071943; FBpp0071854; FBgn0034797 |
GeneIDi | 37641 |
UCSCi | CG12781-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013599 Genomic DNA Translation: AAF46927.2 AY060632 mRNA Translation: AAL28180.1 AE013599 Genomic DNA Translation: AAN16114.1 |
RefSeqi | NP_523815.2, NM_079091.4 NP_726264.1, NM_166569.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9W1X5, 4 interactors |
STRINGi | 7227.FBpp0071853 |
Protocols and materials databases
DNASUi | 37641 |
Genome annotation databases
EnsemblMetazoai | FBtr0071942; FBpp0071853; FBgn0034797 FBtr0071943; FBpp0071854; FBgn0034797 |
GeneIDi | 37641 |
UCSCi | CG12781-RA, d. melanogaster |
Organism-specific databases
CTDi | 37641 |
FlyBasei | FBgn0034797, nahoda |
VEuPathDBi | VectorBase:FBgn0034797 |
Phylogenomic databases
eggNOGi | KOG4293, Eukaryota |
GeneTreei | ENSGT00610000087018 |
HOGENOMi | CLU_269388_0_0_1 |
OMAi | LIQNSPW |
OrthoDBi | 1064366at2759 |
Miscellaneous databases
BioGRID-ORCSi | 37641, 0 hits in 1 CRISPR screen |
ChiTaRSi | nahoda, fly |
GenomeRNAii | 37641 |
Gene expression databases
Bgeei | FBgn0034797, Expressed in second segment of antenna (Drosophila) and 39 other tissues |
Family and domain databases
CDDi | cd09631, DOMON_DOH, 2 hits |
InterProi | View protein in InterPro IPR045266, DOH_DOMON IPR005018, DOMON_domain IPR000742, EGF-like_dom IPR013111, EGF_extracell IPR000082, SEA_dom |
Pfami | View protein in Pfam PF07974, EGF_2, 1 hit |
SMARTi | View protein in SMART SM00664, DoH, 2 hits |
PROSITEi | View protein in PROSITE PS50836, DOMON, 2 hits PS00022, EGF_1, 1 hit PS01186, EGF_2, 1 hit PS50026, EGF_3, 1 hit PS50024, SEA, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9W1X5_DROME | |
Accessioni | Q9W1X5Primary (citable) accession number: Q9W1X5 Secondary accession number(s): Q95SR6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | October 1, 2002 | |
Last modified: | January 19, 2022 | |
This is version 180 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |