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Protein

Nuclear pore complex protein Nup214

Gene

Nup214

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex including emb and phosphorylated Mad.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • nuclear localization sequence binding Source: GO_Central
  • structural constituent of nuclear pore Source: GO_Central

GO - Biological processi

  • mRNA transport Source: UniProtKB-KW
  • negative regulation of protein export from nucleus Source: FlyBase
  • positive regulation of RNA export from nucleus Source: UniProtKB
  • protein import into nucleus Source: UniProtKB
  • protein localization to nuclear pore Source: FlyBase

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-DME-191859 snRNP Assembly
R-DME-3301854 Nuclear Pore Complex (NPC) Disassembly
R-DME-3371453 Regulation of HSF1-mediated heat shock response
R-DME-4551638 SUMOylation of chromatin organization proteins
R-DME-4615885 SUMOylation of DNA replication proteins
R-DME-5578749 Transcriptional regulation by small RNAs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nuclear pore complex protein Nup214
Alternative name(s):
214 kDa nucleoporin
Short name:
DNup214
Nucleoporin Nup214
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nup214Imported
ORF Names:CG3820
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0010660 Nup214

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Nuclear pore complex, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002048601 – 1711Nuclear pore complex protein Nup214Add BLAST1711

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9W1X4

PRoteomics IDEntifications database

More...
PRIDEi
Q9W1X4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0010660 Expressed in 26 organ(s), highest expression level in embryo

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9W1X4 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with mbo/Nup88 to form components of the nuclear pore complex, of which emb is also a member.1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
70095, 11 interactors

Database of interacting proteins

More...
DIPi
DIP-18878N

Protein interaction database and analysis system

More...
IntActi
Q9W1X4, 3 interactors

Molecular INTeraction database

More...
MINTi
Q9W1X4

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0071905

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9W1X4

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9W1X4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati472 – 4731Curated2
Repeati486 – 4872Curated2
Repeati497 – 4983Curated2
Repeati511 – 5124Curated2
Repeati514 – 5155Curated2
Repeati535 – 5366Curated2
Repeati588 – 5897Curated2
Repeati598 – 5998Curated2
Repeati1009 – 10109Curated2
Repeati1075 – 107610Curated2
Repeati1077 – 107811Curated2
Repeati1097 – 109812Curated2
Repeati1106 – 110713Curated2
Repeati1135 – 113614Curated2
Repeati1218 – 121915Curated2
Repeati1229 – 123016Curated2
Repeati1240 – 124117Curated2
Repeati1356 – 135718Curated2
Repeati1388 – 138919Curated2
Repeati1399 – 140020Curated2
Repeati1434 – 143521Curated2
Repeati1449 – 145022Curated2
Repeati1458 – 145923Curated2
Repeati1472 – 147324Curated2
Repeati1481 – 148225Curated2
Repeati1487 – 148826Curated2
Repeati1507 – 150827Curated2
Repeati1512 – 151328Curated2
Repeati1539 – 154029Curated2
Repeati1547 – 154830Curated2
Repeati1562 – 156331Curated2
Repeati1571 – 157232Curated2
Repeati1584 – 158533Curated2
Repeati1588 – 158934Curated2
Repeati1601 – 160235Curated2
Repeati1617 – 161836Curated2
Repeati1623 – 162437Curated2
Repeati1629 – 163038Curated2
Repeati1635 – 163639Curated2
Repeati1641 – 164240Curated2
Repeati1647 – 164841Curated2
Repeati1650 – 165142Curated2
Repeati1662 – 166343Curated2
Repeati1686 – 168744Curated2
Repeati1702 – 170345Curated2

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni472 – 170345 X 2 AA repeats of F-GCuratedAdd BLAST1232
Regioni650 – 672Leucine-zipper 1Add BLAST23
Regioni767 – 788Leucine-zipper 2Add BLAST22

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi900 – 953Pro-richAdd BLAST54
Compositional biasi1152 – 1305Thr-richAdd BLAST154
Compositional biasi1356 – 1707Gly/Phe-richAdd BLAST352

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains FG repeats. FG repeats are interaction sites for karyopherins (importins, exportins) and form probably an affinity gradient, guiding the transport proteins unidirectionally with their cargo through the NPC. FG repeat regions are highly flexible and lack ordered secondary structure. The overall conservation of FG repeats regarding exact sequence, spacing, and repeat unit length is limited. FG-rich region are required for emb localization to the nuclear pore complex.1 Publication

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3630 Eukaryota
ENOG410YBVS LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000165854

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9W1X4

KEGG Orthology (KO)

More...
KOi
K14317

Identification of Orthologs from Complete Genome Data

More...
OMAi
NQTSQWS

Database of Orthologous Groups

More...
OrthoDBi
EOG091G02Y1

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9W1X4

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026054 Nucleoporin
IPR015943 WD40/YVTN_repeat-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR23193 PTHR23193, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9W1X4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQNAPDCED TQDFQFKLHH KIVAFKKCGE PRSNVNLLAV SSSRGLLFAG
60 70 80 90 100
SPTQPELKVI IVKDLVNAKS TAQQPQARLV PLPSIPNYIA CSSDGNLLAV
110 120 130 140 150
NHTQNGTSLL SIYAVLSFMT PDVRPVYNIR LAAEDHVHGV QLLWNPVLPN
160 170 180 190 200
SLAVVLSNGA LAMYALKEGG NFEMHSLDKN QQVKCGCWSP KGKQIVLGFP
210 220 230 240 250
GGTVKQFKPD LTLAKTLLCP PNIHDAPFDT IAIQWLSTFQ FAVIFLQHGE
260 270 280 290 300
DCSPSLYILN APKAGAPSYI NYYDICYSMN GPRNHQFVFS HVPQWNLLLV
310 320 330 340 350
VSANGVEVGI MRSTEAGDTP AWQQLTLLDE ARIEMPLSED KDETFPLGFA
360 370 380 390 400
FDTSTTHQLT INEKKLQTMP MVHVLSSDGE LLSFNFLNVL PTAVSVCSPP
410 420 430 440 450
PPVADTSGQF KPLNMLLASE EEEQPAWAAS PSKAPAATPA ASSDISFAFT
460 470 480 490 500
PNTVTSTPAP SKDKQPSLFS GFGAAAAKAP APQLSFGTAP TSSPVSFGAP
510 520 530 540 550
TTNAAKPTTP FGGFGTQATT TAMGSMFSAS GANAFGGMAL NKPAIASVTP
560 570 580 590 600
RTAAPGSTVP ATPASAPANK PLYTVPLTFT PVDTKPATSA PPQIADESLK
610 620 630 640 650
PDDTEPIIKD MIALQIEAFS KDIQKQKEQT KELLKGIAAP SALRAYAKRL
660 670 680 690 700
DDLQELNEQA KDVEFELDVQ GLRQGLNEAY AIVAECRGKL EIYRKPEITR
710 720 730 740 750
LMNSSSCDPS GRRMLARLQS YVAANEAQLR LAQQHVDLQW EQFQDVVRRN
760 770 780 790 800
SKSRMHMPCL EGIYQRLTRL QNLTSNQRIV QNNIKSKLKE RGLLQAALLD
810 820 830 840 850
QEKSRTRTNE AVDTLTDSIL TMSLSQVVDS NAAKLTRERL QKIRNIVQLQ
860 870 880 890 900
KINVICPQRP DRVGLKSEVI LETKRRAEQI KRAAAKPATA NKYTQAAVAP
910 920 930 940 950
PSPPDVAPTP AVAPMPQATV TVAPPLPKPM PSIPSVVEKP GVPTHPTTPV
960 970 980 990 1000
ATPFSFSQSI PFVKTSTVTP TTNTVTPGEA AKPGLSIFGG STISSFSFGG
1010 1020 1030 1040 1050
GAAKSALSFG TGSPAVAAPT PKPNPLSAVE KPTPEPTKPK EQKAAESKEF
1060 1070 1080 1090 1100
KAVQPETEES KVPQKPKAET ENKSFGFGGF TGTGGTVGNT SSSPFSFGGL
1110 1120 1130 1140 1150
GSSLGFGGTA AAVPKSEPSS TATTSVATSA STAPFGIFSA ALAKPSNSEP
1160 1170 1180 1190 1200
ITTVTSNTTT ITSKPTNVIA SSSVTDAPSV TTTNAVTSST DPIGGLFSSV
1210 1220 1230 1240 1250
TICKPNTPAD TTKPANIFGG GLSAGSFSFG GTIDASKGLF GSTKPVATAP
1260 1270 1280 1290 1300
TSVTEANNKT DPISTTPSAI STTTATTTVS SPAVVPAAVT AAVPATSSTT
1310 1320 1330 1340 1350
VTSSTAVPGS AFSFSNAFST LSAGGAAAPT TSASAPLAAK SPTATSTGNN
1360 1370 1380 1390 1400
SSNSVFGGGF AVATSTAAPV ASPFQSAAKS PVSSANIFGS IPKAETSVFG
1410 1420 1430 1440 1450
GATTAPSNTT AAATPDAPPA GLFASAAISN PSPFGSPTTR APASGGNIFG
1460 1470 1480 1490 1500
QAVKPSVFGQ PAQAGDSGGS IFGGGSASTP FGSSSIFGGG NTQGAVGAPA
1510 1520 1530 1540 1550
AGSTSIFGQK VFGQSSAAAP AAGGNIFSNP VGSPQASPFG GGGNSIFGSP
1560 1570 1580 1590 1600
ATAPPASGGS IFGGGSSSGG FGSFTQTTPA QGGFGGGFGQ GGGGSVAQTG
1610 1620 1630 1640 1650
FGSPQAPQQQ TTTPGGFGAK PVFGGSPAFG ASPTFGGGAT FGSPKGFGGF
1660 1670 1680 1690 1700
GGASPVASPP PFGAAAKPAQ GNIFETLGGQ ESGLSFGNLA QTGNSNAQKP
1710
AFGGSSFMNY R
Length:1,711
Mass (Da):175,176
Last modified:October 1, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7C73E46C789E55ED
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti72A → G in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti126V → I in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti520T → N in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti902S → P in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti1143A → T in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti1162T → A in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti1174V → A in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti1246V → L in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti1267P → A in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti1319S → G in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti1344A → S in AAM11320 (PubMed:12537569).Curated1
Sequence conflicti1385A → G in AAM11320 (PubMed:12537569).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF46928.2
AY094967 mRNA Translation: AAM11320.1

NCBI Reference Sequences

More...
RefSeqi
NP_652039.2, NM_143782.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0071996; FBpp0071905; FBgn0010660

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
46091

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG3820

UCSC genome browser

More...
UCSCi
CG3820-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF46928.2
AY094967 mRNA Translation: AAM11320.1
RefSeqiNP_652039.2, NM_143782.3

3D structure databases

ProteinModelPortaliQ9W1X4
SMRiQ9W1X4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi70095, 11 interactors
DIPiDIP-18878N
IntActiQ9W1X4, 3 interactors
MINTiQ9W1X4
STRINGi7227.FBpp0071905

Proteomic databases

PaxDbiQ9W1X4
PRIDEiQ9W1X4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0071996; FBpp0071905; FBgn0010660
GeneIDi46091
KEGGidme:Dmel_CG3820
UCSCiCG3820-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8021
FlyBaseiFBgn0010660 Nup214

Phylogenomic databases

eggNOGiKOG3630 Eukaryota
ENOG410YBVS LUCA
GeneTreeiENSGT00940000165854
InParanoidiQ9W1X4
KOiK14317
OMAiNQTSQWS
OrthoDBiEOG091G02Y1
PhylomeDBiQ9W1X4

Enzyme and pathway databases

ReactomeiR-DME-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-DME-191859 snRNP Assembly
R-DME-3301854 Nuclear Pore Complex (NPC) Disassembly
R-DME-3371453 Regulation of HSF1-mediated heat shock response
R-DME-4551638 SUMOylation of chromatin organization proteins
R-DME-4615885 SUMOylation of DNA replication proteins
R-DME-5578749 Transcriptional regulation by small RNAs

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
46091

Protein Ontology

More...
PROi
PR:Q9W1X4

Gene expression databases

BgeeiFBgn0010660 Expressed in 26 organ(s), highest expression level in embryo
GenevisibleiQ9W1X4 DM

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR026054 Nucleoporin
IPR015943 WD40/YVTN_repeat-like_dom_sf
PANTHERiPTHR23193 PTHR23193, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNU214_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W1X4
Secondary accession number(s): Q8T3K4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: October 1, 2002
Last modified: December 5, 2018
This is version 140 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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