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Entry version 139 (16 Oct 2019)
Sequence version 3 (15 Jan 2008)
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Protein

Probable G-protein coupled receptor Mth-like 10

Gene

mthl10

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • G protein-coupled receptor activity Source: FlyBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Protein family/group databases

Transport Classification Database

More...
TCDBi
9.A.14.14.1 the g-protein-coupled receptor (gpcr) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable G-protein coupled receptor Mth-like 10
Alternative name(s):
Protein methuselah-like 10
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mthl10
Synonyms:mth2
ORF Names:CG17061
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0035132 mthl10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini33 – 250ExtracellularSequence analysisAdd BLAST218
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei251 – 271Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini272 – 280CytoplasmicSequence analysis9
Transmembranei281 – 301Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini302 – 312ExtracellularSequence analysisAdd BLAST11
Transmembranei313 – 333Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini334 – 353CytoplasmicSequence analysisAdd BLAST20
Transmembranei354 – 374Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini375 – 404ExtracellularSequence analysisAdd BLAST30
Transmembranei405 – 425Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini426 – 466CytoplasmicSequence analysisAdd BLAST41
Transmembranei467 – 487Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini488 – 498ExtracellularSequence analysisAdd BLAST11
Transmembranei499 – 519Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini520 – 585CytoplasmicSequence analysisAdd BLAST66

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 32Sequence analysisAdd BLAST32
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001303133 – 585Probable G-protein coupled receptor Mth-like 10Add BLAST553

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi56 ↔ 110By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi63N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi72N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi112 ↔ 117By similarity
Disulfide bondi121 ↔ 216By similarity
Disulfide bondi122 ↔ 135By similarity
Glycosylationi142N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi152N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi157N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi177 ↔ 236By similarity
Glycosylationi198N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi223N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9W0R5

PRoteomics IDEntifications database

More...
PRIDEi
Q9W0R5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0035132 Expressed in 22 organ(s), highest expression level in crop (Drosophila)

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9W0R5 differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9W0R5 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
63613, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0072472

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9W0R5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IWM1 Eukaryota
ENOG4111I4H LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000166745

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9W0R5

KEGG Orthology (KO)

More...
KOi
K04599

Identification of Orthologs from Complete Genome Data

More...
OMAi
FRPCTEM

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9W0R5

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00251 Mth_Ecto, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR010596 Methuselah_N_dom
IPR036272 Methuselah_N_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00002 7tm_2, 1 hit
PF06652 Methuselah_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF63877 SSF63877, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform B (identifier: Q9W0R5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPKKIHQPGG SLYCGVTLLG VLCLVVFRLI PGIPFGTYVM AERDHYHTID
60 70 80 90 100
DPNVPCNFYD TVNLTGHRLF PNGSYDYYGT IVPAELVGTY DYIHSSLTER
110 120 130 140 150
IEVREHVRGC VCKFKSCLNI CCPWRQVFNS EVDGCIIDHS DNRTWPDPPM
160 170 180 190 200
LNITFRNEST ILVNMFTQFA IQSFRPCPKM FSLQPETNNW DDYLLFENGS
210 220 230 240 250
MLRVDDKLLI RKNEFCMVPT YVNESDMFYT IHPANCDMQD DHSTVKIINS
260 270 280 290 300
YAMMFSIPFM MLTIAVYLLI PELRNQHGKS LVCYLIGLSV GYSSLCYVQL
310 320 330 340 350
YQVDATGVTC KVFGYTAYFF FMGAYMWLSV ISFDLWHNFR GTRGINRFQE
360 370 380 390 400
KKRFLFYSLY SWGIALVFLA FTYCAQQLTN LPANLKPGIG DGVYCWLDMS
410 420 430 440 450
NWAAMIYFYG PILAIVVANT IMFIMTAIKI HGVQREMARI IASENSTKNL
460 470 480 490 500
RTEKDKRFYR AWSNYRFGLF LRLFLIMGIT WLTELISYFV GSDKGWSKLF
510 520 530 540 550
YISDLANAMQ GFLIFMLFVM KKKVKHLITN RCSSVRDGSN QRQSQYSTKT
560 570 580
TSSSVANLSL HEKPSVEKPL VISSSVDPQK TTIFR
Note: No experimental confirmation available.
Length:585
Mass (Da):67,406
Last modified:January 15, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF1DE309DA35F014C
GO
Isoform A (identifier: Q9W0R5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     457-466: Missing.
     532-585: CSSVRDGSNQ...VDPQKTTIFR → TIRVRSLRQT...STSGIHSHEV

Note: No experimental confirmation available.
Show »
Length:577
Mass (Da):66,387
Checksum:i1EA40CA7652154FB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9NEX4M9NEX4_DROME
Methuselah-like 10, isoform D
mthl10 anon-WO0170980.166, anon-WO0170980.167, Dmel\CG17061, mth2, mthl-10
557Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9ND17M9ND17_DROME
Methuselah-like 10, isoform C
mthl10 anon-WO0170980.166, anon-WO0170980.167, Dmel\CG17061, mth2, mthl-10
584Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PGK2M9PGK2_DROME
Methuselah-like 10, isoform E
mthl10 anon-WO0170980.166, anon-WO0170980.167, Dmel\CG17061, mth2, mthl-10
575Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti150M → V in strain: ZIM(S)24. 1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_030270457 – 466Missing in isoform A. Curated10
Alternative sequenceiVSP_030271532 – 585CSSVR…TTIFR → TIRVRSLRQTESVTMGPTSF SMKQRFMDASNQIRKLVVIR NAFANGSTSGIHSHEV in isoform A. CuratedAdd BLAST54

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF47378.2
AE014296 Genomic DNA Translation: AAO41210.2
AF300364, AF300363 Genomic DNA Translation: AAK97869.1
AF300366, AF300365 Genomic DNA Translation: AAK97870.1
AF300368, AF300367 Genomic DNA Translation: AAK97871.1
AF300370, AF300369 Genomic DNA Translation: AAK97872.1
AF300372, AF300371 Genomic DNA Translation: AAK97873.1
AF300374, AF300373 Genomic DNA Translation: AAK97874.1
AF300376, AF300375 Genomic DNA Translation: AAK97875.1
AF300378, AF300377 Genomic DNA Translation: AAK97876.1
AF300380, AF300379 Genomic DNA Translation: AAK97877.1
AF300382, AF300381 Genomic DNA Translation: AAK97878.1
AF300384, AF300383 Genomic DNA Translation: AAK97879.1
AF300386, AF300385 Genomic DNA Translation: AAK97880.1
AF300388, AF300387 Genomic DNA Translation: AAK97881.1
AF300390, AF300389 Genomic DNA Translation: AAK97882.1
AF300392, AF300391 Genomic DNA Translation: AAK97883.1
AF300394, AF300393 Genomic DNA Translation: AAK97884.1
AF300396, AF300395 Genomic DNA Translation: AAK97885.1
AF300398, AF300397 Genomic DNA Translation: AAK97886.1
AF300400, AF300399 Genomic DNA Translation: AAK97887.1
AF300402, AF300401 Genomic DNA Translation: AAK97888.1
AF300404, AF300403 Genomic DNA Translation: AAK97889.1
AF300406, AF300405 Genomic DNA Translation: AAK97890.1
AF300408, AF300407 Genomic DNA Translation: AAK97891.1

NCBI Reference Sequences

More...
RefSeqi
NP_612030.2, NM_138186.3 [Q9W0R5-2]
NP_788446.2, NM_176268.3 [Q9W0R5-1]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0072572; FBpp0072471; FBgn0035132 [Q9W0R5-2]
FBtr0072573; FBpp0072472; FBgn0035132 [Q9W0R5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
38057

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG17061

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF47378.2
AE014296 Genomic DNA Translation: AAO41210.2
AF300364, AF300363 Genomic DNA Translation: AAK97869.1
AF300366, AF300365 Genomic DNA Translation: AAK97870.1
AF300368, AF300367 Genomic DNA Translation: AAK97871.1
AF300370, AF300369 Genomic DNA Translation: AAK97872.1
AF300372, AF300371 Genomic DNA Translation: AAK97873.1
AF300374, AF300373 Genomic DNA Translation: AAK97874.1
AF300376, AF300375 Genomic DNA Translation: AAK97875.1
AF300378, AF300377 Genomic DNA Translation: AAK97876.1
AF300380, AF300379 Genomic DNA Translation: AAK97877.1
AF300382, AF300381 Genomic DNA Translation: AAK97878.1
AF300384, AF300383 Genomic DNA Translation: AAK97879.1
AF300386, AF300385 Genomic DNA Translation: AAK97880.1
AF300388, AF300387 Genomic DNA Translation: AAK97881.1
AF300390, AF300389 Genomic DNA Translation: AAK97882.1
AF300392, AF300391 Genomic DNA Translation: AAK97883.1
AF300394, AF300393 Genomic DNA Translation: AAK97884.1
AF300396, AF300395 Genomic DNA Translation: AAK97885.1
AF300398, AF300397 Genomic DNA Translation: AAK97886.1
AF300400, AF300399 Genomic DNA Translation: AAK97887.1
AF300402, AF300401 Genomic DNA Translation: AAK97888.1
AF300404, AF300403 Genomic DNA Translation: AAK97889.1
AF300406, AF300405 Genomic DNA Translation: AAK97890.1
AF300408, AF300407 Genomic DNA Translation: AAK97891.1
RefSeqiNP_612030.2, NM_138186.3 [Q9W0R5-2]
NP_788446.2, NM_176268.3 [Q9W0R5-1]

3D structure databases

SMRiQ9W0R5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi63613, 1 interactor
STRINGi7227.FBpp0072472

Protein family/group databases

TCDBi9.A.14.14.1 the g-protein-coupled receptor (gpcr) family

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

Proteomic databases

PaxDbiQ9W0R5
PRIDEiQ9W0R5

Genome annotation databases

EnsemblMetazoaiFBtr0072572; FBpp0072471; FBgn0035132 [Q9W0R5-2]
FBtr0072573; FBpp0072472; FBgn0035132 [Q9W0R5-1]
GeneIDi38057
KEGGidme:Dmel_CG17061

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
38057
FlyBaseiFBgn0035132 mthl10

Phylogenomic databases

eggNOGiENOG410IWM1 Eukaryota
ENOG4111I4H LUCA
GeneTreeiENSGT00940000166745
InParanoidiQ9W0R5
KOiK04599
OMAiFRPCTEM
PhylomeDBiQ9W0R5

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
38057

Protein Ontology

More...
PROi
PR:Q9W0R5

Gene expression databases

BgeeiFBgn0035132 Expressed in 22 organ(s), highest expression level in crop (Drosophila)
ExpressionAtlasiQ9W0R5 differential
GenevisibleiQ9W0R5 DM

Family and domain databases

CDDicd00251 Mth_Ecto, 1 hit
InterProiView protein in InterPro
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR010596 Methuselah_N_dom
IPR036272 Methuselah_N_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF06652 Methuselah_N, 1 hit
SUPFAMiSSF63877 SSF63877, 1 hit
PROSITEiView protein in PROSITE
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTH10_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W0R5
Secondary accession number(s): Q7YWL1
, Q86BK3, Q95NU7, Q95YN4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: January 15, 2008
Last modified: October 16, 2019
This is version 139 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  3. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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