Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 169 (29 Sep 2021)
Sequence version 1 (01 May 2000)
Previous versions | rss
Add a publicationFeedback
Protein

DNA repair protein Rev1

Gene

Rev1

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Deoxycytidyl transferase involved in DNA repair (PubMed:22532806).

Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents (By similarity).

During homologous recombination (HR) repair of DNA double-strand breaks (DSBs) regulates the extent of repair synthesis (PubMed:22532806).

Possibly recruits the DNA polymerase zeta complex or another translesion polymerase to early DSB repair intermediates to initiate repair synthesis, while also blocking the access of more processive polymerases preventing them from acting during the initial stages of HR repair (PubMed:22532806).

By similarity1 Publication

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+Note: Binds 2 magnesium ions.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi279MagnesiumPROSITE-ProRule annotation1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei284Substrate discriminationPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei373dCTPBy similarity1
Metal bindingi421MagnesiumPROSITE-ProRule annotation1
Binding sitei421dCTPBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei422PROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi361 – 367dCTP bindingBy similarity7

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Nucleotidyltransferase, Transferase
Biological processDNA damage, DNA repair, DNA synthesis
LigandMagnesium, Metal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-110312, Translesion synthesis by REV1
R-DME-5655862, Translesion synthesis by POLK
R-DME-5656121, Translesion synthesis by POLI

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA repair protein Rev1UniRule annotation (EC:2.7.7.-UniRule annotation)
Alternative name(s):
Reversionless protein 11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rev11 PublicationImported
ORF Names:CG12189Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0035150, Rev1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:FBgn0035150

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Highly sensitive to ionizing radiation due to defects in homologous recombination (HR) repair. The percentage of full HR repair is normal but the length of the repair synthesis tracts is increased.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004487431 – 995DNA repair protein Rev1Add BLAST995

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9W0P2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0035150, Expressed in egg chamber and 37 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9W0P2, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via C-terminus) with DNApol-eta/DNApolH (via C-terminal regions).

Interacts (via C-terminus) with DNApol-iota/DNApolI.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9W0P2, 8 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0072456

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9W0P2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 121BRCTPROSITE-ProRule annotationAdd BLAST87
Domaini275 – 505UmuCPROSITE-ProRule annotationAdd BLAST231

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni135 – 164DisorderedSequence analysisAdd BLAST30
Regioni182 – 211DisorderedSequence analysisAdd BLAST30
Regioni696 – 868Interaction with DNApol-iota/DNApolI1 PublicationAdd BLAST173
Regioni878 – 995Interaction with DNApol-eta/DNApolH1 PublicationAdd BLAST118

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi141 – 164Basic and acidic residuesSequence analysisAdd BLAST24

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA polymerase type-Y family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2093, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156374

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003901_0_2_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
DEMFVEL

Database of Orthologous Groups

More...
OrthoDBi
299766at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9W0P2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.58.1280, 1 hit
3.30.1490.100, 1 hit
3.30.70.270, 1 hit
3.40.50.10190, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001357, BRCT_dom
IPR036420, BRCT_dom_sf
IPR043502, DNA/RNA_pol_sf
IPR036775, DNA_pol_Y-fam_lit_finger_sf
IPR017961, DNA_pol_Y-fam_little_finger
IPR012112, REV1
IPR031991, Rev1_C
IPR038401, Rev1_C_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR001126, UmuC

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16589, BRCT_2, 1 hit
PF00817, IMS, 1 hit
PF11799, IMS_C, 1 hit
PF16727, REV1_C, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036573, REV1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00292, BRCT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF100879, SSF100879, 1 hit
SSF52113, SSF52113, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50172, BRCT, 1 hit
PS50173, UMUC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9W0P2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRDEDNGFS EWGGYFEAKK SKLEEQFAAA SDPFRKSDLF QGISIFVNGR
60 70 80 90 100
TDPSADELKR IMMVHGGTFH HYERSHTTYI IASVLPDVKV RNMNLSKFIS
110 120 130 140 150
AKWVVDCLEK KKIVDYKPYL LYTNQKTSQP MLIFGKPKDN GANESKSDVE
160 170 180 190 200
PPKDKAEVEV DSTKDETQME LGGILKNLQQ AVATSPEKEA SASESKITNL
210 220 230 240 250
STTSNNSTTA RTAADPNFLS EFYKNSRLHH IATLGAGFKQ YVCRLRQKHG
260 270 280 290 300
TQGFPKRETL KSLANSHHNC LERYVMHIDM DCFFVSVGLR TRPELRGLPI
310 320 330 340 350
AVTHSKGGNA ATDVPVHPQA DRKAELELFA QRFEHHFHDG DKAEKVRSGF
360 370 380 390 400
DKKMSLSEIA SCSYEAREKG IRNGMFVGQA LKLCPELKTI PYDFEGYKEV
410 420 430 440 450
AFTLYDTVAQ YTLNIEAVSC DEMFVELTDL AHELNVDVMA FVSHLRQEVY
460 470 480 490 500
SKTGCPCSAG VAGNKLLARM ATKEAKPNGQ FLLDSSNDIL AYMAPMSLDL
510 520 530 540 550
LPGVGSSISH KLKQAGLNNC GDVQNTTLEK MEKVLGKKLG QNLFQNCRGI
560 570 580 590 600
DDRPLAYEQI RKTVSAEMNF GIRFTNSVEC EQFLCQLSEE VTKRLVEIRR
610 620 630 640 650
KARSINLKIM VRAAEAPVET SKYMGHGVCD IINKSSLIKY ATDDVNVITT
660 670 680 690 700
VVLDLMKDAD IPPDELRGLG IHLTRLEDAN EVRKENNIKE MFGKMSEMRK
710 720 730 740 750
DKPIPQGAVG DKSIGDDKVN KPLVFENKPK PREPRNVLSM LTAAAVSRKS
760 770 780 790 800
VTEDRSQRGT SKPITRPLSL VPKLDEDVLA QLPEDIRLEV IANREEHLCI
810 820 830 840 850
AEYDGYRSPQ YPTLRSPPLL NPYVTTNVSP LKATDLKPST SRAAVARLQK
860 870 880 890 900
RKERKEQEHY IRSDQIVADY IDDLPDFVNP HILKLISHPV EMPELLMGDN
910 920 930 940 950
YKDLLNDWVS REEVPKPNDV DLILKQVSRM IKNDQLDHVC DVMKYWCRII
960 970 980 990
NMKRSSSCCW HVAYKHIEES IQNQMLTIEG YSLLFIEYIR CIKCS
Length:995
Mass (Da):112,414
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8647D89E66ECB6B6
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence ABY21724 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti690E → Q in AAL39416 (PubMed:12537569).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB049435 mRNA Translation: BAB15801.1
AE014296 Genomic DNA Translation: AAF47401.1
BT031311 mRNA Translation: ABY21724.1 Different initiation.
AY069271 mRNA Translation: AAL39416.1

NCBI Reference Sequences

More...
RefSeqi
NP_612047.1, NM_138203.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0072557; FBpp0072456; FBgn0035150

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
38079

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG12189

UCSC genome browser

More...
UCSCi
CG12189-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049435 mRNA Translation: BAB15801.1
AE014296 Genomic DNA Translation: AAF47401.1
BT031311 mRNA Translation: ABY21724.1 Different initiation.
AY069271 mRNA Translation: AAL39416.1
RefSeqiNP_612047.1, NM_138203.3

3D structure databases

SMRiQ9W0P2
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9W0P2, 8 interactors
STRINGi7227.FBpp0072456

Proteomic databases

PaxDbiQ9W0P2

Genome annotation databases

EnsemblMetazoaiFBtr0072557; FBpp0072456; FBgn0035150
GeneIDi38079
KEGGidme:Dmel_CG12189
UCSCiCG12189-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51455
FlyBaseiFBgn0035150, Rev1
VEuPathDBiVectorBase:FBgn0035150

Phylogenomic databases

eggNOGiKOG2093, Eukaryota
GeneTreeiENSGT00940000156374
HOGENOMiCLU_003901_0_2_1
OMAiDEMFVEL
OrthoDBi299766at2759
PhylomeDBiQ9W0P2

Enzyme and pathway databases

ReactomeiR-DME-110312, Translesion synthesis by REV1
R-DME-5655862, Translesion synthesis by POLK
R-DME-5656121, Translesion synthesis by POLI

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
38079, 1 hit in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
38079

Protein Ontology

More...
PROi
PR:Q9W0P2

Gene expression databases

BgeeiFBgn0035150, Expressed in egg chamber and 37 other tissues
ExpressionAtlasiQ9W0P2, baseline and differential

Family and domain databases

Gene3Di1.20.58.1280, 1 hit
3.30.1490.100, 1 hit
3.30.70.270, 1 hit
3.40.50.10190, 1 hit
InterProiView protein in InterPro
IPR001357, BRCT_dom
IPR036420, BRCT_dom_sf
IPR043502, DNA/RNA_pol_sf
IPR036775, DNA_pol_Y-fam_lit_finger_sf
IPR017961, DNA_pol_Y-fam_little_finger
IPR012112, REV1
IPR031991, Rev1_C
IPR038401, Rev1_C_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR001126, UmuC
PfamiView protein in Pfam
PF16589, BRCT_2, 1 hit
PF00817, IMS, 1 hit
PF11799, IMS_C, 1 hit
PF16727, REV1_C, 1 hit
PIRSFiPIRSF036573, REV1, 1 hit
SMARTiView protein in SMART
SM00292, BRCT, 1 hit
SUPFAMiSSF100879, SSF100879, 1 hit
SSF52113, SSF52113, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS50172, BRCT, 1 hit
PS50173, UMUC, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiREV1_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9W0P2
Secondary accession number(s): A9UNE7, Q8T9I8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 11, 2019
Last sequence update: May 1, 2000
Last modified: September 29, 2021
This is version 169 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again