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UniProtKB - Q9W0M4 (Q9W0M4_DROME)
Protein
Endoplasmic reticulum transmembrane protein
Gene
Dmel\CG13887
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
UniRule annotationGO - Biological processi
- endoplasmic reticulum to Golgi vesicle-mediated transport Source: GO_Central
- intracellular protein transport Source: UniProtKB-UniRule
- protein localization to endoplasmic reticulum exit site Source: GO_Central
Keywordsi
Biological process | ER-Golgi transportUniRule annotationARBA annotation, Protein transportUniRule annotationARBA annotation, Transport |
Enzyme and pathway databases
Reactomei | R-DME-75153, Apoptotic execution phase |
Names & Taxonomyi
Protein namesi | Recommended name: Endoplasmic reticulum transmembrane proteinUniRule annotation |
Gene namesi | Name:Dmel\CG13887Imported ORF Names:CG13887Imported, Dmel_CG13887Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0035165, CG13887 |
VEuPathDBi | VectorBase:FBgn0035165 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane UniRule annotationARBA annotation; Multi-pass membrane protein UniRule annotationARBA annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: GO_Central
Other locations
- endomembrane system Source: FlyBase
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 7 – 28 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 48 – 67 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 101 – 118 | HelicalUniRule annotationAdd BLAST | 18 |
Keywords - Cellular componenti
Endoplasmic reticulumUniRule annotationARBA annotation, MembraneExpressioni
Gene expression databases
Bgeei | FBgn0035165, Expressed in seminal fluid secreting gland and 48 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q9W0M4, 2 interactors |
STRINGi | 7227.FBpp0072480 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 133 | Bap31InterPro annotationAdd BLAST | 133 | |
Domaini | 175 – 226 | Bap31_Bap29_CInterPro annotationAdd BLAST | 52 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 180 – 199 | DisorderedSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilARBA annotation, Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG1962, Eukaryota |
GeneTreei | ENSGT00390000011863 |
HOGENOMi | CLU_070975_0_0_1 |
OMAi | EMGLFML |
OrthoDBi | 1514108at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR008417, BAP29/BAP31 IPR040463, BAP29/BAP31_N IPR041672, Bap31/Bap29_C |
PANTHERi | PTHR12701, PTHR12701, 1 hit |
Pfami | View protein in Pfam PF05529, Bap31, 1 hit PF18035, Bap31_Bap29_C, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9W0M4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLVWTLIAG FLYAEIALVL LLVLPVLTPY RWNRFFKSKF LSMLGQQAHI
60 70 80 90 100
YFLLIMGILV IFLLEAIREM RKYSGLQQSN EVHLNVEMQH SMKLFRAQRN
110 120 130 140 150
FYISGFAIFL ALVIRRLVNL ICTQANLMAQ SEASFKQAQS ATAAARSLLE
160 170 180 190 200
NKNTEKAKEA GEDTTLIELN KLRERVQELT SDLNREKKDK EAVKSQAESI
210 220
NREYDRLTEE YSKLQKKITI GGGGNKDD
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketB9EQV3 | B9EQV3_DROME | Endoplasmic reticulum transmembrane... | CG13887-RC Dmel\CG13887, CG13887, Dmel_CG13887 | 184 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF47419.1 AY069750 mRNA Translation: AAL39895.1 AE014296 Genomic DNA Translation: AAN11453.1 AE014296 Genomic DNA Translation: AHN57916.1 |
RefSeqi | NP_001286891.1, NM_001299962.1 NP_612062.1, NM_138218.3 NP_728548.1, NM_167843.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0072583; FBpp0072480; FBgn0035165 FBtr0072584; FBpp0072481; FBgn0035165 FBtr0345588; FBpp0311657; FBgn0035165 |
GeneIDi | 38096 |
UCSCi | CG13887-RB, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF47419.1 AY069750 mRNA Translation: AAL39895.1 AE014296 Genomic DNA Translation: AAN11453.1 AE014296 Genomic DNA Translation: AHN57916.1 |
RefSeqi | NP_001286891.1, NM_001299962.1 NP_612062.1, NM_138218.3 NP_728548.1, NM_167843.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9W0M4, 2 interactors |
STRINGi | 7227.FBpp0072480 |
Protocols and materials databases
DNASUi | 38096 |
Genome annotation databases
EnsemblMetazoai | FBtr0072583; FBpp0072480; FBgn0035165 FBtr0072584; FBpp0072481; FBgn0035165 FBtr0345588; FBpp0311657; FBgn0035165 |
GeneIDi | 38096 |
UCSCi | CG13887-RB, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0035165, CG13887 |
VEuPathDBi | VectorBase:FBgn0035165 |
Phylogenomic databases
eggNOGi | KOG1962, Eukaryota |
GeneTreei | ENSGT00390000011863 |
HOGENOMi | CLU_070975_0_0_1 |
OMAi | EMGLFML |
OrthoDBi | 1514108at2759 |
Enzyme and pathway databases
Reactomei | R-DME-75153, Apoptotic execution phase |
Miscellaneous databases
BioGRID-ORCSi | 38096, 0 hits in 3 CRISPR screens |
ChiTaRSi | CG13887, fly |
GenomeRNAii | 38096 |
Gene expression databases
Bgeei | FBgn0035165, Expressed in seminal fluid secreting gland and 48 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR008417, BAP29/BAP31 IPR040463, BAP29/BAP31_N IPR041672, Bap31/Bap29_C |
PANTHERi | PTHR12701, PTHR12701, 1 hit |
Pfami | View protein in Pfam PF05529, Bap31, 1 hit PF18035, Bap31_Bap29_C, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9W0M4_DROME | |
Accessioni | Q9W0M4Primary (citable) accession number: Q9W0M4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | May 25, 2022 | |
This is version 170 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |