UniProtKB - Q9VZ73 (Q9VZ73_DROME)
Protein
Submitted name:
AT26201p
Gene
Dmel\CG17030
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- ubiquitin conjugating enzyme activity Source: GO_Central
- ubiquitin protein ligase binding Source: GO_Central
- ubiquitin-protein transferase activity Source: FlyBase
GO - Biological processi
- protein polyubiquitination Source: FlyBase
- ubiquitin-dependent protein catabolic process Source: GO_Central
Enzyme and pathway databases
Reactomei | R-DME-1169408, ISG15 antiviral mechanism R-DME-983168, Antigen processing: Ubiquitination & Proteasome degradation |
Names & Taxonomyi
Protein namesi | Submitted name: AT26201pImported |
Gene namesi | Name:Dmel\CG17030Imported ORF Names:CG17030Imported, Dmel_CG17030Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0035584, CG17030 |
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
Other locations
- ubiquitin ligase complex Source: GO_Central
Interactioni
GO - Molecular functioni
- ubiquitin protein ligase binding Source: GO_Central
Protein-protein interaction databases
IntActi | Q9VZ73, 4 interactors |
STRINGi | 7227.FBpp0073230 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 13 – 147 | UBC coreInterPro annotationAdd BLAST | 135 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 160 – 180 | DisorderedSequence analysisAdd BLAST | 21 |
Phylogenomic databases
eggNOGi | KOG0422, Eukaryota |
GeneTreei | ENSGT00940000165322 |
HOGENOMi | CLU_030988_13_3_1 |
OMAi | WHMEMAG |
OrthoDBi | 1420213at2759 |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VZ73-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKKEEPLMD GPKRMNRELA LMLEDKQNLQ FRNLLVEPNN IYKWTGLLMP
60 70 80 90 100
VAPPYDKGAY KMEIDFPLDY PFKPPRIHIN TRMYHLNVNE RGQVCVPILE
110 120 130 140 150
VEHWIPTTRI DQVLQVLLAT INDPQPENAW HIEMAGEYRN DPVRFFKMAD
160 170 180
AWVQKYSEPR PTEEELAKFA RKRKKAMTKK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF47953.1 AY089444 mRNA Translation: AAL90182.1 |
RefSeqi | NP_647941.1, NM_139684.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0073374; FBpp0073230; FBgn0035584 |
GeneIDi | 38591 |
KEGGi | dme:Dmel_CG17030 |
UCSCi | CG17030-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF47953.1 AY089444 mRNA Translation: AAL90182.1 |
RefSeqi | NP_647941.1, NM_139684.3 |
3D structure databases
SMRi | Q9VZ73 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q9VZ73, 4 interactors |
STRINGi | 7227.FBpp0073230 |
Genome annotation databases
EnsemblMetazoai | FBtr0073374; FBpp0073230; FBgn0035584 |
GeneIDi | 38591 |
KEGGi | dme:Dmel_CG17030 |
UCSCi | CG17030-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0035584, CG17030 |
Phylogenomic databases
eggNOGi | KOG0422, Eukaryota |
GeneTreei | ENSGT00940000165322 |
HOGENOMi | CLU_030988_13_3_1 |
OMAi | WHMEMAG |
OrthoDBi | 1420213at2759 |
Enzyme and pathway databases
Reactomei | R-DME-1169408, ISG15 antiviral mechanism R-DME-983168, Antigen processing: Ubiquitination & Proteasome degradation |
Miscellaneous databases
BioGRID-ORCSi | 38591, 0 hits in 1 CRISPR screen |
GenomeRNAii | 38591 |
Gene expression databases
Bgeei | FBgn0035584, Expressed in testis and 17 other tissues |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VZ73_DROME | |
Accessioni | Q9VZ73Primary (citable) accession number: Q9VZ73 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 174 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |