Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 162 (07 Apr 2021)
Sequence version 2 (31 Oct 2006)
Previous versions | rss
Add a publicationFeedback
Protein

Probable histone-lysine N-methyltransferase CG1716

Gene

Set2

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable histone methyltransferase. Histone methylation gives specific tags for epigenetic transcriptional activation or repression (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi17 – 29A.T hook 1Add BLAST13
DNA bindingi197 – 209A.T hook 2Add BLAST13

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, Methyltransferase, Transferase
Biological processTranscription, Transcription regulation
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-5693565, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9VYD1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable histone-lysine N-methyltransferase CG1716 (EC:2.1.1.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Set2
ORF Names:CG1716
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0030486, Set2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002595231 – 2313Probable histone-lysine N-methyltransferase CG1716Add BLAST2313

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei404Phosphothreonine1 Publication1
Modified residuei786Phosphoserine1 Publication1
Modified residuei788Phosphoserine1 Publication1
Modified residuei2130Phosphoserine1 Publication1
Modified residuei2131Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VYD1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9VYD1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0030486, Expressed in oocyte and 40 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VYD1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VYD1, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
58681, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VYD1, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0073610

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1307 – 1360AWSPROSITE-ProRule annotationAdd BLAST54
Domaini1362 – 1479SETPROSITE-ProRule annotationAdd BLAST118
Domaini1486 – 1502Post-SETPROSITE-ProRule annotationAdd BLAST17
Domaini1963 – 1996WWPROSITE-ProRule annotationAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi326 – 672Glu-richAdd BLAST347
Compositional biasi675 – 898Lys-richAdd BLAST224
Compositional biasi983 – 1008Ser-richAdd BLAST26

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4442, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000172873

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000516_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VYD1

Family and domain databases

Conserved Domains Database

More...
CDDi
cd19172, SET_SETD2, 1 hit
cd00201, WW, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1740.100, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017956, AT_hook_DNA-bd_motif
IPR006560, AWS_dom
IPR003616, Post-SET_dom
IPR001214, SET_dom
IPR044437, SETD2/Set2_SET
IPR013257, SRI
IPR038190, SRI_sf
IPR001202, WW_dom
IPR036020, WW_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17907, AWS, 1 hit
PF00856, SET, 1 hit
PF08236, SRI, 1 hit
PF00397, WW, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00384, AT_hook, 2 hits
SM00570, AWS, 1 hit
SM00508, PostSET, 1 hit
SM00317, SET, 1 hit
SM00456, WW, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51045, SSF51045, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51215, AWS, 1 hit
PS50868, POST_SET, 1 hit
PS50280, SET, 1 hit
PS01159, WW_DOMAIN_1, 1 hit
PS50020, WW_DOMAIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VYD1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEESGPPSNP SPVASRGRGR GRPPKVALSA LGNTPPHINP SLKHADAEAS
60 70 80 90 100
PTAPEDQDSG QSECRRSSRK KIIKFDVRDL LNKNRKAHKI QIEARIDSNP
110 120 130 140 150
STGHSQSGTT AASTSMSTAT ASAASASSAA TVSRLFSMFE MSHQSLPPPP
160 170 180 190 200
PPPTALEIFA KPRPTQSLIV AQVTSEPSAV GGAHPVQTMA GLPPVTPRKR
210 220 230 240 250
GRPRKSQLAD AAIIPTVIVP SCSDSDTNST STTTSNMSSD SGELPGFPIQ
260 270 280 290 300
KPKSKLRVSL KRLKLGGRLE SSDSGNSPSS SSPEVEPPAL QDENAMDERP
310 320 330 340 350
KQEQNLSRMV DAEENSDSDS QIIFIEIETE SPKGEEEQEE GRPVEVEPQD
360 370 380 390 400
LIDIDMELAK QEPTPDPEED LDEIMVEVLS GPPSLWSADD EAEEEEDATV
410 420 430 440 450
QRATPPGKEP AADSCSSAPR RSRRSAPLSG SSRQGKTLEE TFAEIAAESS
460 470 480 490 500
KQILEAEESQ DQEEQHILID LIEDTLKSDN IAASLNKDIF EPKVETKATC
510 520 530 540 550
GEVVPRPEMV TEDVYITEGI AATLEKSAVV TKPTTEMIAE TKLSDEVVIE
560 570 580 590 600
PPLKDESDPK QTEVELPESK PAVNIPKSER ILSAEVETTS SPLVPPECCT
610 620 630 640 650
LESVSGPVLL ETSLSTEEKS NENVETTPLK TEAAKEDSPP AAPEEEASNS
660 670 680 690 700
SEEPNFLLED YESNQEQVAE DEMMKCNNQK GQKQTPLPEM KEPEKPVAET
710 720 730 740 750
VSKKEKAMEN PARSSPAIVD KKVRAGEMEK KVVKSTKGTV PEKKMDSKKS
760 770 780 790 800
CAAVTPAKQK ESGKSAKEAI LKKETEKEKS SAKLDSSSPN TLDKKGKDTA
810 820 830 840 850
QWSPQLQTLP KSSTKPPQES APSVISKTTS NQPAPKEEQH AAKKGLSDNS
860 870 880 890 900
PPSVLKAKEK AVSGFVECDA MFKAMDLANA QLRLDEKNKK KLKKVPTKVE
910 920 930 940 950
APPKVEPPTA VPVPGQKKSL SGKTSLRRNT VYEDSPNLER NSSPSSDSAQ
960 970 980 990 1000
ANTSAGKLKP SKVKKKINPR RSTICEAAKD LRSSSSSSTP TREVAASSPV
1010 1020 1030 1040 1050
STSSDSSSKR NGSKRTTSDL DGGSKLDQRR YTICEDRQPE TAIPVPLTKR
1060 1070 1080 1090 1100
RFSMHPKASA NPLHDTLLQT AGKKRGRKEG KESLSRQNSL DSSSSASQGA
1110 1120 1130 1140 1150
PKKKALKSAE ILSAALLETE SSESTSSGSK MSRWDVQTSP ELEAANPFGD
1160 1170 1180 1190 1200
IAKFIEDGVN LLKRDKVDED QRKEGQDEVK READPEEDEF AQRVANMETP
1210 1220 1230 1240 1250
ATTPTPSPTQ SNPEDSASTT TVLKELETGG GVRRSHRIKQ KPQGPRASQG
1260 1270 1280 1290 1300
RGVASVALAP ISMDEQLAEL ANIEAINEQF LRSEGLNTFQ LLKENFYRCA
1310 1320 1330 1340 1350
RQVSQENAEM QCDCFLTGDE EAQGHLSCGA GCINRMLMIE CGPLCSNGAR
1360 1370 1380 1390 1400
CTNKRFQQHQ CWPCRVFRTE KKGCGITAEL LIPPGEFIME YVGEVIDSEE
1410 1420 1430 1440 1450
FERRQHLYSK DRNRHYYFMA LRGEAVIDAT SKGNISRYIN HSCDPNAETQ
1460 1470 1480 1490 1500
KWTVNGELRI GFFSVKPIQP GEEITFDYQY LRYGRDAQRC YCEAANCRGW
1510 1520 1530 1540 1550
IGGEPDSDEG EQLDEESDSD AEMDEEELEA EPEEGQPRKS AKAKAKSKLK
1560 1570 1580 1590 1600
AKLPLATGRK RKEQTKPKDR EYKAGRWLKP SATGSSSSAE KPPKKPKVNK
1610 1620 1630 1640 1650
FQAMLEDPDV VEELSLLRRG GLKNQQDTLR FSRCLVRAKL LKTRLALLRV
1660 1670 1680 1690 1700
LTHGELPCRR LFLDYHGLRL LHAWISENGN DDQLREALLD TLESLPIPNR
1710 1720 1730 1740 1750
TMLSDSRVYQ SVQLWSNSLE QQLAVVPQEK QAALHKRMVA LLQKWQALPE
1760 1770 1780 1790 1800
IFRIPKRERI EQMKEHEREA DRQQKHVHAS TALEDQRERE SSNDRFRQDR
1810 1820 1830 1840 1850
FRRDTTSSRI GKPIRMSGNN TICTITTQQK GSNGAPDGMT RNDNRRRSDI
1860 1870 1880 1890 1900
GPPSEQRRTL SKELRRSLFE RKVALDEAER RVCTEDRLEH ELRCEFFGAD
1910 1920 1930 1940 1950
INTDPKQLPF YQKTDTNEWF NSDDVPVPAP PRTELLTKAL LSPDIDVGQG
1960 1970 1980 1990 2000
ATDVEYKLPP GVDPLPPAWN WQVTSDGDIY YYNLRERISQ WEPPSPEQRL
2010 2020 2030 2040 2050
QTLLEENTTQ QPLHELQIDP AVLENELIQV DTDYVGSLSA KSLAQYIEAK
2060 2070 2080 2090 2100
VRERRDLRRS KLVSIRLISP RRDEDRLYNQ LESRKYKENK EKIRRRKELY
2110 2120 2130 2140 2150
RRRKIEVLPD AVDEIPVPGK ALPIQPYLFS SDEEETKVAA IEQPAAEEEQ
2160 2170 2180 2190 2200
DSLNMAPSTS HAAMAALGKA VAQPTGLGTV GKRKLPMPPS VTVKKHRQEQ
2210 2220 2230 2240 2250
RSKKVKSSQS PLTATSAREA HEKFRFEISG HVANFLRPYR KESCTLGRIT
2260 2270 2280 2290 2300
SDEDYKFLVN RLSYHITTKE MRYCEVSGNP LSCTESVKHK SYDFINQYMR
2310
QKGPVYKKPA END
Length:2,313
Mass (Da):256,791
Last modified:October 31, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i811F133520284E2F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E1JJN9E1JJN9_DROME
SET domain containing 2, isoform B
Set2 dHypb, Dmel\CG1716, dSet2, Hypb, SET2
2,313Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF48273 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAK84931 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti490F → S in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti500C → R in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti509M → L in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti700T → A in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti710N → K in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti737K → R in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti2148E → A in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti2179T → S in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti2202S → N in AAK84931 (PubMed:12537569).Curated1
Sequence conflicti2215T → S in AAK84931 (PubMed:12537569).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48273.2 Sequence problems.
BT025042 mRNA Translation: ABE73213.1
AY050232 mRNA Translation: AAK84931.1 Frameshift.

NCBI Reference Sequences

More...
RefSeqi
NP_001162740.1, NM_001169269.2
NP_572888.2, NM_132660.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0301559; FBpp0290774; FBgn0030486

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
32301

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG1716

UCSC genome browser

More...
UCSCi
CG1716-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48273.2 Sequence problems.
BT025042 mRNA Translation: ABE73213.1
AY050232 mRNA Translation: AAK84931.1 Frameshift.
RefSeqiNP_001162740.1, NM_001169269.2
NP_572888.2, NM_132660.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi58681, 4 interactors
IntActiQ9VYD1, 1 interactor
STRINGi7227.FBpp0073610

PTM databases

iPTMnetiQ9VYD1

Proteomic databases

PaxDbiQ9VYD1

Genome annotation databases

EnsemblMetazoaiFBtr0301559; FBpp0290774; FBgn0030486
GeneIDi32301
KEGGidme:Dmel_CG1716
UCSCiCG1716-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
32301
FlyBaseiFBgn0030486, Set2

Phylogenomic databases

eggNOGiKOG4442, Eukaryota
GeneTreeiENSGT00940000172873
HOGENOMiCLU_000516_0_0_1
InParanoidiQ9VYD1

Enzyme and pathway databases

ReactomeiR-DME-5693565, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
SignaLinkiQ9VYD1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
32301, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
32301

Protein Ontology

More...
PROi
PR:Q9VYD1

Gene expression databases

BgeeiFBgn0030486, Expressed in oocyte and 40 other tissues
ExpressionAtlasiQ9VYD1, baseline and differential
GenevisibleiQ9VYD1, DM

Family and domain databases

CDDicd19172, SET_SETD2, 1 hit
cd00201, WW, 1 hit
Gene3Di1.10.1740.100, 1 hit
InterProiView protein in InterPro
IPR017956, AT_hook_DNA-bd_motif
IPR006560, AWS_dom
IPR003616, Post-SET_dom
IPR001214, SET_dom
IPR044437, SETD2/Set2_SET
IPR013257, SRI
IPR038190, SRI_sf
IPR001202, WW_dom
IPR036020, WW_dom_sf
PfamiView protein in Pfam
PF17907, AWS, 1 hit
PF00856, SET, 1 hit
PF08236, SRI, 1 hit
PF00397, WW, 1 hit
SMARTiView protein in SMART
SM00384, AT_hook, 2 hits
SM00570, AWS, 1 hit
SM00508, PostSET, 1 hit
SM00317, SET, 1 hit
SM00456, WW, 1 hit
SUPFAMiSSF51045, SSF51045, 1 hit
PROSITEiView protein in PROSITE
PS51215, AWS, 1 hit
PS50868, POST_SET, 1 hit
PS50280, SET, 1 hit
PS01159, WW_DOMAIN_1, 1 hit
PS50020, WW_DOMAIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC1716_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VYD1
Secondary accession number(s): Q1RL18, Q961S6, Q9VYD0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: April 7, 2021
This is version 162 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again