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UniProtKB - Q9VY33 (Q9VY33_DROME)
Protein
Submitted name:
Defective proboscis extension response 8, isoform A
Gene
dpr8
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Biological processi
- sensory perception of chemical stimulus Source: FlyBase
- synapse organization Source: FlyBase
Names & Taxonomyi
Protein namesi | Submitted name: Defective proboscis extension response 8, isoform AImportedSubmitted name: Defective proboscis extension response 8, isoform BImportedSubmitted name: GH05565pImported |
Gene namesi | Name:dpr8Imported Synonyms:CG11477Imported, CG14415Imported, CG5291Imported, CT16867Imported, Dmel\CG32600Imported, dpr 8Imported, Dpr-8Imported, Dpr8Imported ORF Names:CG32600Imported, Dmel_CG32600Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0052600, dpr8 |
VEuPathDBi | VectorBase:FBgn0052600 |
Subcellular locationi
Plasma Membrane
- integral component of plasma membrane Source: FlyBase
- neuron projection membrane Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | Sequence analysisAdd BLAST | 21 | |
ChainiPRO_5015100752 | 22 – 344 | Sequence analysisAdd BLAST | 323 |
Interactioni
Binary interactionsi
Protein-protein interaction databases
IntActi | Q9VY33, 13 interactors |
STRINGi | 7227.FBpp0073730 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 42 – 129 | Ig-likeInterPro annotationAdd BLAST | 88 | |
Domaini | 145 – 237 | Ig-likeInterPro annotationAdd BLAST | 93 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 309 – 344 | DisorderedSequence analysisAdd BLAST | 36 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 320 – 337 | Basic and acidic residuesSequence analysisAdd BLAST | 18 |
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG3510, Eukaryota |
HOGENOMi | CLU_046341_3_3_1 |
OMAi | RSNRNCQ |
OrthoDBi | 974511at2759 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR013098, Ig_I-set IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013106, Ig_V-set IPR013151, Immunoglobulin IPR037448, Zig-8 |
PANTHERi | PTHR23279, PTHR23279, 1 hit |
Pfami | View protein in Pfam PF07679, I-set, 1 hit PF00047, ig, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 2 hits SM00408, IGc2, 2 hits SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 2 hits |
i Sequence
Sequence statusi: Complete.
Q9VY33-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTHWIIFLG ILCLLAGCTD GASKRFFTDF LQDLPTPGTG GPTFDTTIGT
60 70 80 90 100
NITGLVGKTV KLTCRVKNLG NRTVSWVRHR DIHLLTVGRY TYTSDQRFEA
110 120 130 140 150
MHSPHAEDWT LRIRYAQRKD SGIYECQIST TPPIGHSVYL NIVEPVTDII
160 170 180 190 200
GGPELHINRG STINLTCIVK FAPEPPPTVI WSHNREIINF DSPRGGISLV
210 220 230 240 250
TEKGVLTTSR LLVQKAITQD SGLYTCTPSN ANPTSVRVHI VDGEHPAAMH
260 270 280 290 300
TGNNGNSTAS QPPVLLPLVL LTCSTLMLLQ LVASCSTLVP ATPPGCRTVQ
310 320 330 340
QASTFAEEKA MGQRSNRNCQ DLQELEESQD LRRRGVERSA VPGT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014298 Genomic DNA Translation: AAF48372.2 AY060637 mRNA Translation: AAL28185.1 AE014298 Genomic DNA Translation: AHN59709.1 |
RefSeqi | NP_001285239.1, NM_001298310.1 NP_727781.1, NM_167408.2 |
Genome annotation databases
EnsemblMetazoai | FBtr0073913; FBpp0073730; FBgn0052600 FBtr0343518; FBpp0310122; FBgn0052600 |
GeneIDi | 32387 |
KEGGi | dme:Dmel_CG32600 |
UCSCi | CG32600-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014298 Genomic DNA Translation: AAF48372.2 AY060637 mRNA Translation: AAL28185.1 AE014298 Genomic DNA Translation: AHN59709.1 |
RefSeqi | NP_001285239.1, NM_001298310.1 NP_727781.1, NM_167408.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9VY33, 13 interactors |
STRINGi | 7227.FBpp0073730 |
Protocols and materials databases
DNASUi | 32387 |
Genome annotation databases
EnsemblMetazoai | FBtr0073913; FBpp0073730; FBgn0052600 FBtr0343518; FBpp0310122; FBgn0052600 |
GeneIDi | 32387 |
KEGGi | dme:Dmel_CG32600 |
UCSCi | CG32600-RA, d. melanogaster |
Organism-specific databases
CTDi | 32387 |
FlyBasei | FBgn0052600, dpr8 |
VEuPathDBi | VectorBase:FBgn0052600 |
Phylogenomic databases
eggNOGi | KOG3510, Eukaryota |
HOGENOMi | CLU_046341_3_3_1 |
OMAi | RSNRNCQ |
OrthoDBi | 974511at2759 |
Miscellaneous databases
BioGRID-ORCSi | 32387, 0 hits in 1 CRISPR screen |
ChiTaRSi | dpr8, fly |
GenomeRNAii | 32387 |
Gene expression databases
Bgeei | FBgn0052600, Expressed in brain and 18 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR013098, Ig_I-set IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013106, Ig_V-set IPR013151, Immunoglobulin IPR037448, Zig-8 |
PANTHERi | PTHR23279, PTHR23279, 1 hit |
Pfami | View protein in Pfam PF07679, I-set, 1 hit PF00047, ig, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 2 hits SM00408, IGc2, 2 hits SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VY33_DROME | |
Accessioni | Q9VY33Primary (citable) accession number: Q9VY33 Secondary accession number(s): Q95SR2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | October 1, 2002 | |
Last modified: | January 19, 2022 | |
This is version 183 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |