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UniProtKB - Q9VXV3 (Q9VXV3_DROME)

Entry version 141 (25 May 2022)
Sequence version 1 (01 May 2000)
Previous versions | rss
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Protein
Submitted name:

Shattered

Gene

shtd

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-DME-141430, Inactivation of APC/C via direct inhibition of the APC/C complex
R-DME-174048, APC/C:Cdc20 mediated degradation of Cyclin B
R-DME-174084, Autodegradation of Cdh1 by Cdh1:APC/C
R-DME-174154, APC/C:Cdc20 mediated degradation of Securin
R-DME-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
R-DME-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-DME-176407, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
R-DME-176408, Regulation of APC/C activators between G1/S and early anaphase
R-DME-176409, APC/C:Cdc20 mediated degradation of mitotic proteins
R-DME-176412, Phosphorylation of the APC/C
R-DME-179409, APC-Cdc20 mediated degradation of Nek2A
R-DME-2467813, Separation of Sister Chromatids
R-DME-2559582, Senescence-Associated Secretory Phenotype (SASP)
R-DME-69017, CDK-mediated phosphorylation and removal of Cdc6
R-DME-983168, Antigen processing: Ubiquitination & Proteasome degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ShatteredImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:shtdImported
Synonyms:APC1Imported, Apc1Imported, Dmel\CG9198Imported, SHTDImported, ShtdImported
ORF Names:CG9198Imported, Dmel_CG9198Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0004391, shtd

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		VectorBase:FBgn0004391

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9VXV3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0004391, Expressed in cleaving embryo and 36 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9VXV3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9VXV3, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q9VXV3, 14 interactors

STRING: functional protein association networks

More...STRINGi		7227.FBpp0073893

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9VXV3

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9VXV3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1815 – 1923APC1_CInterPro annotationAdd BLAST109

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 32DisorderedSequence analysisAdd BLAST32
Regioni556 – 583DisorderedSequence analysisAdd BLAST28
Regioni749 – 774DisorderedSequence analysisAdd BLAST26
Regioni1065 – 1086DisorderedSequence analysisAdd BLAST22

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi749 – 770Polar residuesSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the APC1 family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1858, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000016757

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001202_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9VXV3

Identification of Orthologs from Complete Genome Data

More...OMAi		MQPPDSR

Database of Orthologous Groups

More...OrthoDBi		738153at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9VXV3

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR024990, Apc1
IPR041221, APC1_C
IPR011989, ARM-like

The PANTHER Classification System

More...PANTHERi		PTHR12827, PTHR12827, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12859, ANAPC1, 1 hit
PF18122, APC1_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VXV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIAVAEPPLE FVPRGRQTSA EHPGPHDQPM ARHQLPTTEH LLLQRLQNVN 
        60         70         80         90        100
ISSAGEDCPS GGQESWTVRE LYDDYEASEE RAALRRKLTE RTKRCGLQAT 
       110        120        130        140        150
SLPNRLLNPP LVRRVEPMCD YMVNNEEELY VNRNTVVWTQ GVNDDDDTDN 
       160        170        180        190        200
GVYRRMCFTT DTPVRFACFL NRSFVRGRLA QLKAAVHPDD DHLTAICVMD 
       210        220        230        240        250
QDALRVYCSN GEDFLANLDF PVSQLWQTKY GLLLEKDSSN ALISHMSIPM 
       260        270        280        290        300
PRLFSMSHPL HEACPVVLKT ATGSTGYMTE PEYTVVFTTE ESDLVMLYDA 
       310        320        330        340        350
KFFKHFVARL RKVTPEEINY VSQQMELGQT LMGPRSMAGN SFSSTKQTGA 
       360        370        380        390        400
TPKATNLSFA ARNINTTTTG MGNQFGLSQS QSFSGVLGQS NRASLGTPLS 
       410        420        430        440        450
QLQSSISQQS MSVKDMRKLT HVKPAKPIEP ELCMEHIWTE NIYGTQREFC 
       460        470        480        490        500
EMATRAFIHT DLVGQTFLCY LLARSCRLQL VRLTGYGRGE VQLSTHASTL 
       510        520        530        540        550
AAKDAVGLKR MHMIAVLDPS GSLLLYTGTV LISKVHITPF LAPTSIPTPL 
       560        570        580        590        600
VTPMTAAPSP SASPAPSHVK TPMAAAGPAS GIPSGSSSFV EVRRSSLLPT 
       610        620        630        640        650
KAPGDVAAFE EELHMLSPIQ PQPVSYTQRQ AHNVCKSLRD PAGNRLTLVY 
       660        670        680        690        700
ATGRMLRIAL PFLNDTRLLT RCVATLRQVL SPTQFLDFVI RWYSDRNPPG 
       710        720        730        740        750
SRNYSIEQEW LLFRSTLLAL MGLTAAPDVD AGENYARCAT PPLHTQFGGG 
       760        770        780        790        800
ATATESSDGS SCSSNSTLGG QDEPKKRRIY NDCDDFTDDD WEFLLLQTTL 
       810        820        830        840        850
APCGADGHSY SVNIGALLFR MIPAIFFSLH LLYEDLKLDA DFYGALPYLA 
       860        870        880        890        900
TFLHQLAIDM QLESYVLHYI LDFPELSNRT GKLSLLGAEH GAMMLHQELL 
       910        920        930        940        950
RVPAPSVFAQ LEHIIVGEEE VMPYTFLECV NERSRILLQL VSLVTHGHER 
       960        970        980        990       1000
LNYWWQLLEI PGAVQANFTR RSKRNITADA PRSHQMLQLL LAMRLTRRDI 
      1010       1020       1030       1040       1050
ERFPAAVHLI VAEALEEARL SPPMGCSMAT YELILRPELA AHAQLPFLET 
      1060       1070       1080       1090       1100
STGQPHCGRV YKEDSLSARC PPTGGSETDS PAQLRRDDMD NMDTKLLRLR 
      1110       1120       1130       1140       1150
FPDDMRVDEV RRLLNSSEPV VIEVQQAPGT SDHEFIEEQE KQLFALCSRT 
      1160       1170       1180       1190       1200
MTLPVGRGMF TLRTMLPRPS ESLTMPKLCL LGKEPLKGTT IEMQQIEFPA 
      1210       1220       1230       1240       1250
NMQMWPSFHN GVATGLKISP QAQDIDSNWI VYNKPKTHSH NALEHAGFLM 
      1260       1270       1280       1290       1300
ALGLNGHLKT LSFMSVYKYL VKCDEMTNVG LLLGISAAHR GTMDTKTTKL 
      1310       1320       1330       1340       1350
LSVHLEALLP ATAMELDIPQ STQVAAIMGV GLLYQGSAKR HIAEVLLQEI 
      1360       1370       1380       1390       1400
GRPPGPEMEN SIERESYAMT AGLSLGLVTL GQGESPAGLR DLQLPDTLHY 
      1410       1420       1430       1440       1450
YMVGGVKRPI GGSQKEKYRL ASFQVREGDT VNIDVTAPGA TLALGLMFFN 
      1460       1470       1480       1490       1500
SGNAAIAEWM QPPDSRYLLD MVRPDFLLLR TISRGLILWQ DVRPDNAWFQ 
      1510       1520       1530       1540       1550
AQFPRALRAH LKLPFYENEY APEDYDVDYE AISQAYCNIM AGAAFCIGLK 
      1560       1570       1580       1590       1600
YAGTENLVAF ATLRSVIKDF LRFPSRPMGE CAGRTTVESC LMVLLISISL 
      1610       1620       1630       1640       1650
VFAGSGNCEI LRIIRFLRSR VGPQYPHITY GSHMAIHMSL GLLFLGAGRF 
      1660       1670       1680       1690       1700
TISQTPESIA ALVCAFFPKF PIHSNDNRYH LQALRHLYVL AVEPRLFLPR 
      1710       1720       1730       1740       1750
DIDTNKLCLA NISVLEVGAT ELRRLPIAPC ILPVLSTLQQ VVVDDENYWP 
      1760       1770       1780       1790       1800
VCFERSRNWD QLEKALEMSA PIDIKKRTGC LSHLEDPDRL KSMLAQTLTM 
      1810       1820       1830       1840       1850
EQSICWQIDM NDLQQFASER MVKQFLSRCL DTKGTDLSPP ELMKRHQVML 
      1860       1870       1880       1890       1900
LFYNAVVKDR MHFLPVYLTL YDHVTKSMPN NIDVWQMKLI DAYLSRSQES 
      1910       1920       1930       1940       1950
EHPLISVELI QMMQELFKQE MEDSTRELCL PLREFLSRRR LDPSYVTTVS 
      1960       1970       1980       1990       2000
GPDLQRAFCV INYYNLLPNM LNGVDLSTGT VNYMRLLYEF RRLNLGAHTI 
      2010       2020       2030
FGLMKILQSL ATEVVTLDEA ALLAYTMGDQ
Length:2,030
Mass (Da):227,274
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB9D22DC906C7C1C5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48455.1

NCBI Reference Sequences

More...RefSeqi		NP_573025.2, NM_132797.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0074077; FBpp0073893; FBgn0004391

Database of genes from NCBI RefSeq genomes

More...GeneIDi		32473

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG9198

UCSC genome browser

More...UCSCi		CG9198-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48455.1
RefSeqiNP_573025.2, NM_132797.3

3D structure databases

AlphaFoldDBiQ9VXV3
SMRiQ9VXV3
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9VXV3, 14 interactors
STRINGi7227.FBpp0073893

Proteomic databases

PaxDbiQ9VXV3

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		32473

Genome annotation databases

EnsemblMetazoaiFBtr0074077; FBpp0073893; FBgn0004391
GeneIDi32473
KEGGidme:Dmel_CG9198
UCSCiCG9198-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		32473
FlyBaseiFBgn0004391, shtd
VEuPathDBiVectorBase:FBgn0004391

Phylogenomic databases

eggNOGiKOG1858, Eukaryota
GeneTreeiENSGT00390000016757
HOGENOMiCLU_001202_1_0_1
InParanoidiQ9VXV3
OMAiMQPPDSR
OrthoDBi738153at2759
PhylomeDBiQ9VXV3

Enzyme and pathway databases

ReactomeiR-DME-141430, Inactivation of APC/C via direct inhibition of the APC/C complex
R-DME-174048, APC/C:Cdc20 mediated degradation of Cyclin B
R-DME-174084, Autodegradation of Cdh1 by Cdh1:APC/C
R-DME-174154, APC/C:Cdc20 mediated degradation of Securin
R-DME-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
R-DME-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-DME-176407, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
R-DME-176408, Regulation of APC/C activators between G1/S and early anaphase
R-DME-176409, APC/C:Cdc20 mediated degradation of mitotic proteins
R-DME-176412, Phosphorylation of the APC/C
R-DME-179409, APC-Cdc20 mediated degradation of Nek2A
R-DME-2467813, Separation of Sister Chromatids
R-DME-2559582, Senescence-Associated Secretory Phenotype (SASP)
R-DME-69017, CDK-mediated phosphorylation and removal of Cdc6
R-DME-983168, Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		32473, 1 hit in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		shtd, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		32473

Gene expression databases

BgeeiFBgn0004391, Expressed in cleaving embryo and 36 other tissues
ExpressionAtlasiQ9VXV3, baseline and differential
GenevisibleiQ9VXV3, DM

Family and domain databases

Gene3Di1.25.10.10, 2 hits
InterProiView protein in InterPro
IPR024990, Apc1
IPR041221, APC1_C
IPR011989, ARM-like
PANTHERiPTHR12827, PTHR12827, 1 hit
PfamiView protein in Pfam
PF12859, ANAPC1, 1 hit
PF18122, APC1_C, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VXV3_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VXV3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 25, 2022
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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