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Entry version 162 (11 Dec 2019)
Sequence version 1 (01 May 2000)
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Protein
Submitted name:

Bazooka, isoform A

Gene

baz

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Bazooka, isoform AImported
Submitted name:
LD13977pImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:bazImported
Synonyms:BAZImported, BazImported, BazookaImported, CG5055-RAImported, D-Par3Imported, D-par3Imported, Dmel\CG5055Imported, dPar-3Imported, l(1)G0484Imported, PAR-3Imported, Par-3Imported, par-3Imported, PAR3Imported, Par3Imported, par3Imported
ORF Names:CG5055Imported, Dmel_CG5055Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0000163 baz

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0000163 Expressed in 31 organ(s), highest expression level in embryo

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9VX75, 9 interactors

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini311 – 394PDZInterPro annotationAdd BLAST84
Domaini444 – 529PDZInterPro annotationAdd BLAST86
Domaini624 – 716PDZInterPro annotationAdd BLAST93

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni75 – 138DisorderedSequence analysisAdd BLAST64
Regioni163 – 186DisorderedSequence analysisAdd BLAST24
Regioni211 – 233DisorderedSequence analysisAdd BLAST23
Regioni259 – 298DisorderedSequence analysisAdd BLAST40
Regioni557 – 590DisorderedSequence analysisAdd BLAST34
Regioni597 – 616DisorderedSequence analysisAdd BLAST20
Regioni744 – 860DisorderedSequence analysisAdd BLAST117
Regioni904 – 951DisorderedSequence analysisAdd BLAST48
Regioni1100 – 1133DisorderedSequence analysisAdd BLAST34
Regioni1150 – 1172DisorderedSequence analysisAdd BLAST23
Regioni1209 – 1273DisorderedSequence analysisAdd BLAST65
Regioni1291 – 1341DisorderedSequence analysisAdd BLAST51
Regioni1356 – 1377DisorderedSequence analysisAdd BLAST22
Regioni1413 – 1464DisorderedSequence analysisAdd BLAST52

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi92 – 138PolarSequence analysisAdd BLAST47
Compositional biasi259 – 287PolarSequence analysisAdd BLAST29
Compositional biasi571 – 590PolarSequence analysisAdd BLAST20
Compositional biasi744 – 786PolarSequence analysisAdd BLAST43
Compositional biasi822 – 858PolarSequence analysisAdd BLAST37
Compositional biasi915 – 951PolarSequence analysisAdd BLAST37
Compositional biasi1105 – 1123PolyampholyteSequence analysisAdd BLAST19
Compositional biasi1151 – 1165PolarSequence analysisAdd BLAST15
Compositional biasi1209 – 1241PolarSequence analysisAdd BLAST33
Compositional biasi1311 – 1341PolarSequence analysisAdd BLAST31

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410ITAJ Eukaryota
ENOG410ZDVK LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183214

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021922 Par3/HAL_N
IPR001478 PDZ
IPR036034 PDZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12053 Par3_HAL_N_term, 1 hit
PF00595 PDZ, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228 PDZ, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106 PDZ, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9VX75-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKVTVCFGDV RILVPCGSGE LLVRDLVKEA TRRYIKAAGK PDSWVTVTHL
60 70 80 90 100
QTQSGILDPD DCVRDVADDR EQILAHFDDP GPDPGVPQGG GDGASGSSSV
110 120 130 140 150
GTGSPDIFRD PTNTEAPTCP RDLSTPHIEV TSTTSGPMAG LGVGLMVRRS
160 170 180 190 200
SDPNLLASLK AEGSNKRWSA AAPHYAGGDS PERLFLDKAG GQLSPQWEED
210 220 230 240 250
DDPSHQLKEQ LLHQQQPHAA NGGSSSGNHQ PFARSGRLSM QFLGDGNGYK
260 270 280 290 300
WMEAAEKLQN QPPAQQTYQQ GSHHAGHGQN GAYSSKSLPR ESKRKEPLGQ
310 320 330 340 350
AYESIREKDG EMLLIINEYG SPLGLTALPD KEHGGGLLVQ HVEPGSRAER
360 370 380 390 400
GRLRRDDRIL EINGIKLIGL TESQVQEQLR RALESSELRV RVLRGDRNRR
410 420 430 440 450
QQRDSKVAEM VEVATVSPTR KPHAAPVGTS LQVANTRKLG RKIEIMLKKG
460 470 480 490 500
PNGLGFSVTT RDNPAGGHCP IYIKNILPRG AAIEDGRLKP GDRLLEVDGT
510 520 530 540 550
PMTGKTQTDV VAILRGMPAG ATVRIVVSRQ QELAEQADQP AEKSAGVAVA
560 570 580 590 600
PSVAPPAVPA AAAPAPPIPV QKSSSARSLF THQQQSQLNE SQHFIDAGSE
610 620 630 640 650
SAASNDSLPP SSNSWHSREE LTLHIPVHDT EKAGLGVSVK GKTCSNLNAS
660 670 680 690 700
GSSASSGSNG LMKHDGDLGI FVKNVIHGGA ASRDGRLRMN DQLLSVNGVS
710 720 730 740 750
LRGQNNAEAM ETLRRAMVNT PGKHPGTITL LVGRKILRSA SSSDILDHSN
760 770 780 790 800
SHSHSHSNSS GGSNSNGSGN NNNSSSNASD NSGATVIYLS PEKREQRCNG
810 820 830 840 850
GGGGGSAGNE MNRWSNPVLD RLTGGICSSN SAQPSSQQSH QQQPHPSQQQ
860 870 880 890 900
QQQRRLPAAP VCSSAALRNE SYYMATNDNW SPAQMHLMTA HGNTALLIED
910 920 930 940 950
DAEPMSPTLP ARPHDGQHCN TSSANPSQNL AVGNQGPPIN TVPGTPSTSS
960 970 980 990 1000
NFDATYSSQL SLETNSGVEH FSRDALGRRS ISEKHHAALD ARETGTYQRN
1010 1020 1030 1040 1050
KKLREERERE RRIQLTKSAV YGGSIESLTA RIASANAQFS GYKHAKTASS
1060 1070 1080 1090 1100
IEQRETQQQL AAAEAEARDQ LGDLGPSLGM KKSSSLESLQ TMVQELQMSD
1110 1120 1130 1140 1150
EPRGHQALRA PRGRGREDSL RAAVVSEPDA SKPRKTWLLE DGDHEGGFAS
1160 1170 1180 1190 1200
QRNGPFQSSL NDGKHGCKSS RAKKPSILRG IGHMFRFGKN RKDGVVPVDN
1210 1220 1230 1240 1250
YAVNISPPTS VVSTATSPQL QQQQQQQLQQ HQQQQQIPTA ALAALERNGK
1260 1270 1280 1290 1300
PPAYQPPPPL PAPNGVGSNG IHQNDIFNHR YQHYANYEDL HQQHQQHQIS
1310 1320 1330 1340 1350
RRHQHYHSQR SARSQDVSMH STSSGSQPGS LAQPQAQSNG VRPMSSYYEY
1360 1370 1380 1390 1400
ETVQQQRVGS IKHSHSSSAT SSSSSPINVP HWKAAAMNGY SPASLNSSAR
1410 1420 1430 1440 1450
SRGPFVTQVT IREQSSGGIP AHLLQQHQQQ QLQQQQPTYQ TVQKMSGPSQ
1460
YGSAAGSQPH ASKV
Length:1,464
Mass (Da):157,427
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i089B43434CA818C3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q0KHR3Q0KHR3_DROME
Bazooka, isoform B
baz BAZ, Baz, Bazooka, D-Par3, D-par3
1,520Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X2JFU8X2JFU8_DROME
Bazooka, isoform C
baz BAZ, Baz, Bazooka, D-Par3, D-par3
1,499Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X2JCB3X2JCB3_DROME
Bazooka, isoform D
baz BAZ, Baz, Bazooka, D-Par3, D-par3
1,485Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48703.1
BT032834 mRNA Translation: ACD81848.1

NCBI Reference Sequences

More...
RefSeqi
NP_001334669.1, NM_001347807.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0074388; FBpp0074162; FBgn0000163

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
32703

UCSC genome browser

More...
UCSCi
CG5055-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48703.1
BT032834 mRNA Translation: ACD81848.1
RefSeqiNP_001334669.1, NM_001347807.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9VX75, 9 interactors

Genome annotation databases

EnsemblMetazoaiFBtr0074388; FBpp0074162; FBgn0000163
GeneIDi32703
UCSCiCG5055-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
32703
FlyBaseiFBgn0000163 baz

Phylogenomic databases

eggNOGiENOG410ITAJ Eukaryota
ENOG410ZDVK LUCA
GeneTreeiENSGT00950000183214

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
baz fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
32703

Gene expression databases

BgeeiFBgn0000163 Expressed in 31 organ(s), highest expression level in embryo

Family and domain databases

InterProiView protein in InterPro
IPR021922 Par3/HAL_N
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF12053 Par3_HAL_N_term, 1 hit
PF00595 PDZ, 3 hits
SMARTiView protein in SMART
SM00228 PDZ, 3 hits
SUPFAMiSSF50156 SSF50156, 3 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VX75_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VX75
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: December 11, 2019
This is version 162 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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