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UniProtKB - Q9VWF2 (SAYP_DROME)

Entry version 152 (02 Dec 2020)
Sequence version 3 (05 Jul 2004)
Previous versions | rss
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Protein

Supporter of activation of yellow protein

Gene

e(y)3

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential transcription regulator during early development. Coactivates transcription of some euchromatin genes and repress transcription in of euchromatin genes translocated to heterochromatin.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri1694 – 1751PHD-type 1; degeneratePROSITE-ProRule annotationAdd BLAST58
Zinc fingeri1753 – 1796PHD-type 2; degeneratePROSITE-ProRule annotationAdd BLAST44

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Repressor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Supporter of activation of yellow protein
Alternative name(s):
Protein enhancer of yellow 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:e(y)3
Synonyms:l(1)G0084, SAYP
ORF Names:CG12238
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0087008, e(y)3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000593401 – 2006Supporter of activation of yellow proteinAdd BLAST2006

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9VWF2

PRoteomics IDEntifications database

More...PRIDEi		Q9VWF2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed. Highly expressed in ovary. Expressed in nursing cells and growing oocytes at all stages of development and accumulates in mature oocytes. Expressed in the nuclei of syncytium blastoderm of early embryos and in the nuclei of different tissues of late embryos, larvae, and adults.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed throughout all stages of development. Expressed at higher level in adult females.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0087008, Expressed in embryo and 56 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9VWF2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9VWF2, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		59261, 28 interactors

Database of interacting proteins

More...DIPi		DIP-48904N

Protein interaction database and analysis system

More...IntActi		Q9VWF2, 26 interactors

Molecular INTeraction database

More...MINTi		Q9VWF2

STRING: functional protein association networks

More...STRINGi		7227.FBpp0074531

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9VWF2

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1340 – 1573SAYAdd BLAST234

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi328 – 345Poly-SerAdd BLAST18
Compositional biasi375 – 379Poly-Gln5
Compositional biasi645 – 648Poly-Thr4
Compositional biasi1024 – 1028Poly-Asn5
Compositional biasi1045 – 1052Poly-Ser8
Compositional biasi1629 – 1635Poly-Ser7
Compositional biasi1960 – 1965Poly-Ser6

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PHD fingers mediate the transcription repression in heterochromatin.1 Publication
The SAY domain is essential for fly viability and transcription activation.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SAYP family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1694 – 1751PHD-type 1; degeneratePROSITE-ProRule annotationAdd BLAST58
Zinc fingeri1753 – 1796PHD-type 2; degeneratePROSITE-ProRule annotationAdd BLAST44

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1512, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155172

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9VWF2

Database of Orthologous Groups

More...OrthoDBi		708781at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9VWF2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00249, PHD, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57903, SSF57903, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01359, ZF_PHD_1, 2 hits
PS50016, ZF_PHD_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9VWF2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNDLRQQQMV AATSSSGSES GTAVESAAAT STAGSAGAAG RPQSNCSANS 
        60         70         80         90        100
NAKSVAASST SEEEQRVSST SSPAQRDQQL NADRDREQEP EPQQQQQREE 
       110        120        130        140        150
ALQHQHNQPG HITSTTASPP PTLPPPTTPC DDAPSTTGAS ASASSASGEA 
       160        170        180        190        200
PSAASAAGAA GGPMAATALE VESEERDGHK IILKLSKHAN PNSNANESQP 
       210        220        230        240        250
GGDERRVEPL RIQLPCGGAE GGLVAKQQDA FDADASSCSS SCAEDEVATT 
       260        270        280        290        300
LGQQLRNTPH IVPKLTIRAA NERRVGSVVP KLTIKLPENP AASGSNSNSG 
       310        320        330        340        350
SCSAAVSGAQ SAMPAKNDAH LSSLSPASAS SSSASSSSSS SSSSSLAEMQ 
       360        370        380        390        400
TVPKLMIKTT LAGSSCISSS EELPQQQQQI PKLTIKTGGG GQEHVHTVIM 
       410        420        430        440        450
THDLNNAQSI PKLTIKTKSI EMIEDEQAAK LEQQLQPLPK LTIKNLCSPK 
       460        470        480        490        500
HKVRAVLEEK PPTAASKLAI PKPTPNPTPA PMTNGGESNS SSQEFCGFSD 
       510        520        530        540        550
PDADIAAPAS DDVRRNSDDM VIDDSLSKEH DPKIFHNLPP MPASNGIASG 
       560        570        580        590        600
GSKASKASKS AQSQHNVVDM VDLTSSPSPG SSPTHVPNNF TGRISPKGLL 
       610        620        630        640        650
IDCLRMQTAI GCYVPEEADS RVRPAASPNS NILLSQLTAP AKSFTTTTPK 
       660        670        680        690        700
SKSSKYPQLT ERLMANGSGT GGGSVIAAES EAVVGPLPAA NPAQSIIESI 
       710        720        730        740        750
EILDTPDGSP RVAYMDEDSN PMLNKHLQTI HKLAMDHGVE QRMDTQDNNN 
       760        770        780        790        800
ENHLKRTNSE GNESPSSRLP PSKQRRLDND ENDQQTQNCH DPARKCSESL 
       810        820        830        840        850
QALPPSHRSR KQKHERILNT DLEGSLFPPT QQQSISTPDQ NGALSSEVEG 
       860        870        880        890        900
EDAKAQDPLE PATPQPPPVA TPAGTGKKRG RPKRIQNQSS PDGGGAVTPK 
       910        920        930        940        950
PGTPQEEANS AVKSRRVQLL RKRLAIDMVS VGQEQADMKA KEKESSVGVP 
       960        970        980        990       1000
NARVEDGLAE TLESPKTRDH RPLRATRRTT TSTNTNLQPT PKSTRKRQSK 
      1010       1020       1030       1040       1050
ASVQQSQLPP PTMAQFGSSE SESNNNNNSS ISFALSAQID LTMCSSSSST 
      1060       1070       1080       1090       1100
SSGAAANQQV IGGSGSSSML PPTTILSSSD PLPDVIFQPN DFSSIMATQQ 
      1110       1120       1130       1140       1150
LRSSRPSSIS CGSTGGSQPD CHDEDNYTSA LDNSGDETAL PMPPTRGRGR 
      1160       1170       1180       1190       1200
GRRSRGGRGR GSSSVDRAVS VGGTASTTPA TQPRAPRMSR GASAVAKAIA 
      1210       1220       1230       1240       1250
MSRPRCVGGL KHQPDPERLK GLFSPSPQVF EEDTRMSADL SNSNQSMASL 
      1260       1270       1280       1290       1300
MEPPLTPQKQ PDFLNNEESQ SSMVSNVSMM DSNQGQSADA ILGSALKRPK 
      1310       1320       1330       1340       1350
KKKMETCVAE DTDYSASSIA EYDWPPPKGC CPSKNRDTFM IQEQVALYLG 
      1360       1370       1380       1390       1400
ITSFKRKYPD LPRRSVDMEE RNWLQEKGLV SEKLCDLGIT AVWASDILDI 
      1410       1420       1430       1440       1450
MYADFFDKYE EYKEYIRRKH LREIEAKQKA LGLTVGAGRG LQARDRAMLS 
      1460       1470       1480       1490       1500
ATKWNAYFNK SRKDERQSCM DLQTFTINQP QPRTAPTCTR LERSTSDLIR 
      1510       1520       1530       1540       1550
AVAEEANIPA PPNLLPPRDY DEAFRNSDYA YPLTVVPDQF SMAYRQFEPA 
      1560       1570       1580       1590       1600
ELRAYPLDTA LDKPPTDLMA QLLQAKSEAV GSDEIKTSAP APKDLGQEQS 
      1610       1620       1630       1640       1650
AIKSVTVTAP VRRSRRSTRQ QTDKVRTASS SSTSSAQSVS SASSGNGSSS 
      1660       1670       1680       1690       1700
DTESGDESDF SSTSSCSSST GASSGAGSED EDGNECSSSV RLSTCGVCLR 
      1710       1720       1730       1740       1750
SQHRNARDMP EAFIRCYTCR KRVHPSCVDM PPRMVGRVRN YNWQCAGCKC 
      1760       1770       1780       1790       1800
CIKCRSSQRP GKMLYCEQCD RGYHIYCLGL RTVPDGRWSC ERCCFCMRCG 
      1810       1820       1830       1840       1850
ATKPEGLPQV AALSQASGGP SANGDRSKAA RNKRLKWVHE YRIDHVTKIR 
      1860       1870       1880       1890       1900
EHAAMFCVPC ARNKPAKRQS AAGAAGAAAV TPVLEATSAQ TDDSPMPSPG 
      1910       1920       1930       1940       1950
LTTNGGRALS PTAALSPKAA VPVASLPPVL EATTVTTNIA GTIGRRQAGN 
      1960       1970       1980       1990       2000
AVNITTMQCS SSSSSNFSGN GVTEDAANVT ATGTATAAAG APAATPIGIA 

PPPVVA
Length:2,006
Mass (Da):212,726
Last modified:July 5, 2004 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1567640FB4E5084
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PI16M9PI16_DROME
Enhancer of yellow 3, isoform C
e(y)3 Dmel\CG12238, e(y)[3], l(1)G0084, l(1)G0266, l(1)G0283
2,012Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PHZ0M9PHZ0_DROME
Enhancer of yellow 3, isoform D
e(y)3 Dmel\CG12238, e(y)[3], l(1)G0084, l(1)G0266, l(1)G0283
2,011Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PHL0M9PHL0_DROME
Enhancer of yellow 3, isoform B
e(y)3 Dmel\CG12238, e(y)[3], l(1)G0084, l(1)G0266, l(1)G0283
2,006Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAM48352 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48990.3
BT099689 mRNA Translation: ACV44475.1
AY118323 mRNA Translation: AAM48352.1 Different initiation.

NCBI Reference Sequences

More...RefSeqi		NP_001259718.1, NM_001272789.1
NP_001259721.1, NM_001272792.1
NP_608334.3, NM_134490.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0074762; FBpp0074531; FBgn0087008
FBtr0334278; FBpp0306393; FBgn0087008
FBtr0334281; FBpp0306396; FBgn0087008

Database of genes from NCBI RefSeq genomes

More...GeneIDi		32965

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG12238

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48990.3
BT099689 mRNA Translation: ACV44475.1
AY118323 mRNA Translation: AAM48352.1 Different initiation.
RefSeqiNP_001259718.1, NM_001272789.1
NP_001259721.1, NM_001272792.1
NP_608334.3, NM_134490.3

3D structure databases

SMRiQ9VWF2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi59261, 28 interactors
DIPiDIP-48904N
IntActiQ9VWF2, 26 interactors
MINTiQ9VWF2
STRINGi7227.FBpp0074531

Proteomic databases

PaxDbiQ9VWF2
PRIDEiQ9VWF2

Genome annotation databases

EnsemblMetazoaiFBtr0074762; FBpp0074531; FBgn0087008
FBtr0334278; FBpp0306393; FBgn0087008
FBtr0334281; FBpp0306396; FBgn0087008
GeneIDi32965
KEGGidme:Dmel_CG12238

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		32965
FlyBaseiFBgn0087008, e(y)3

Phylogenomic databases

eggNOGiKOG1512, Eukaryota
GeneTreeiENSGT00940000155172
InParanoidiQ9VWF2
OrthoDBi708781at2759
PhylomeDBiQ9VWF2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		32965, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		32965

Protein Ontology

More...PROi		PR:Q9VWF2

Gene expression databases

BgeeiFBgn0087008, Expressed in embryo and 56 other tissues
ExpressionAtlasiQ9VWF2, baseline and differential
GenevisibleiQ9VWF2, DM

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD
SMARTiView protein in SMART
SM00249, PHD, 2 hits
SUPFAMiSSF57903, SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359, ZF_PHD_1, 2 hits
PS50016, ZF_PHD_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSAYP_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VWF2
Secondary accession number(s): C7LAD9, Q7JW70
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: December 2, 2020
This is version 152 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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