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Entry version 152 (02 Dec 2020)
Sequence version 3 (05 Jul 2004)
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Protein

Supporter of activation of yellow protein

Gene

e(y)3

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential transcription regulator during early development. Coactivates transcription of some euchromatin genes and repress transcription in of euchromatin genes translocated to heterochromatin.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri1694 – 1751PHD-type 1; degeneratePROSITE-ProRule annotationAdd BLAST58
Zinc fingeri1753 – 1796PHD-type 2; degeneratePROSITE-ProRule annotationAdd BLAST44

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Repressor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Supporter of activation of yellow protein
Alternative name(s):
Protein enhancer of yellow 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:e(y)3
Synonyms:l(1)G0084, SAYP
ORF Names:CG12238
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0087008, e(y)3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000593401 – 2006Supporter of activation of yellow proteinAdd BLAST2006

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VWF2

PRoteomics IDEntifications database

More...
PRIDEi
Q9VWF2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed. Highly expressed in ovary. Expressed in nursing cells and growing oocytes at all stages of development and accumulates in mature oocytes. Expressed in the nuclei of syncytium blastoderm of early embryos and in the nuclei of different tissues of late embryos, larvae, and adults.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed throughout all stages of development. Expressed at higher level in adult females.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0087008, Expressed in embryo and 56 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VWF2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VWF2, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
59261, 28 interactors

Database of interacting proteins

More...
DIPi
DIP-48904N

Protein interaction database and analysis system

More...
IntActi
Q9VWF2, 26 interactors

Molecular INTeraction database

More...
MINTi
Q9VWF2

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0074531

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VWF2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1340 – 1573SAYAdd BLAST234

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi328 – 345Poly-SerAdd BLAST18
Compositional biasi375 – 379Poly-Gln5
Compositional biasi645 – 648Poly-Thr4
Compositional biasi1024 – 1028Poly-Asn5
Compositional biasi1045 – 1052Poly-Ser8
Compositional biasi1629 – 1635Poly-Ser7
Compositional biasi1960 – 1965Poly-Ser6

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PHD fingers mediate the transcription repression in heterochromatin.1 Publication
The SAY domain is essential for fly viability and transcription activation.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SAYP family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1694 – 1751PHD-type 1; degeneratePROSITE-ProRule annotationAdd BLAST58
Zinc fingeri1753 – 1796PHD-type 2; degeneratePROSITE-ProRule annotationAdd BLAST44

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1512, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155172

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VWF2

Database of Orthologous Groups

More...
OrthoDBi
708781at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VWF2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00249, PHD, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57903, SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01359, ZF_PHD_1, 2 hits
PS50016, ZF_PHD_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9VWF2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNDLRQQQMV AATSSSGSES GTAVESAAAT STAGSAGAAG RPQSNCSANS
60 70 80 90 100
NAKSVAASST SEEEQRVSST SSPAQRDQQL NADRDREQEP EPQQQQQREE
110 120 130 140 150
ALQHQHNQPG HITSTTASPP PTLPPPTTPC DDAPSTTGAS ASASSASGEA
160 170 180 190 200
PSAASAAGAA GGPMAATALE VESEERDGHK IILKLSKHAN PNSNANESQP
210 220 230 240 250
GGDERRVEPL RIQLPCGGAE GGLVAKQQDA FDADASSCSS SCAEDEVATT
260 270 280 290 300
LGQQLRNTPH IVPKLTIRAA NERRVGSVVP KLTIKLPENP AASGSNSNSG
310 320 330 340 350
SCSAAVSGAQ SAMPAKNDAH LSSLSPASAS SSSASSSSSS SSSSSLAEMQ
360 370 380 390 400
TVPKLMIKTT LAGSSCISSS EELPQQQQQI PKLTIKTGGG GQEHVHTVIM
410 420 430 440 450
THDLNNAQSI PKLTIKTKSI EMIEDEQAAK LEQQLQPLPK LTIKNLCSPK
460 470 480 490 500
HKVRAVLEEK PPTAASKLAI PKPTPNPTPA PMTNGGESNS SSQEFCGFSD
510 520 530 540 550
PDADIAAPAS DDVRRNSDDM VIDDSLSKEH DPKIFHNLPP MPASNGIASG
560 570 580 590 600
GSKASKASKS AQSQHNVVDM VDLTSSPSPG SSPTHVPNNF TGRISPKGLL
610 620 630 640 650
IDCLRMQTAI GCYVPEEADS RVRPAASPNS NILLSQLTAP AKSFTTTTPK
660 670 680 690 700
SKSSKYPQLT ERLMANGSGT GGGSVIAAES EAVVGPLPAA NPAQSIIESI
710 720 730 740 750
EILDTPDGSP RVAYMDEDSN PMLNKHLQTI HKLAMDHGVE QRMDTQDNNN
760 770 780 790 800
ENHLKRTNSE GNESPSSRLP PSKQRRLDND ENDQQTQNCH DPARKCSESL
810 820 830 840 850
QALPPSHRSR KQKHERILNT DLEGSLFPPT QQQSISTPDQ NGALSSEVEG
860 870 880 890 900
EDAKAQDPLE PATPQPPPVA TPAGTGKKRG RPKRIQNQSS PDGGGAVTPK
910 920 930 940 950
PGTPQEEANS AVKSRRVQLL RKRLAIDMVS VGQEQADMKA KEKESSVGVP
960 970 980 990 1000
NARVEDGLAE TLESPKTRDH RPLRATRRTT TSTNTNLQPT PKSTRKRQSK
1010 1020 1030 1040 1050
ASVQQSQLPP PTMAQFGSSE SESNNNNNSS ISFALSAQID LTMCSSSSST
1060 1070 1080 1090 1100
SSGAAANQQV IGGSGSSSML PPTTILSSSD PLPDVIFQPN DFSSIMATQQ
1110 1120 1130 1140 1150
LRSSRPSSIS CGSTGGSQPD CHDEDNYTSA LDNSGDETAL PMPPTRGRGR
1160 1170 1180 1190 1200
GRRSRGGRGR GSSSVDRAVS VGGTASTTPA TQPRAPRMSR GASAVAKAIA
1210 1220 1230 1240 1250
MSRPRCVGGL KHQPDPERLK GLFSPSPQVF EEDTRMSADL SNSNQSMASL
1260 1270 1280 1290 1300
MEPPLTPQKQ PDFLNNEESQ SSMVSNVSMM DSNQGQSADA ILGSALKRPK
1310 1320 1330 1340 1350
KKKMETCVAE DTDYSASSIA EYDWPPPKGC CPSKNRDTFM IQEQVALYLG
1360 1370 1380 1390 1400
ITSFKRKYPD LPRRSVDMEE RNWLQEKGLV SEKLCDLGIT AVWASDILDI
1410 1420 1430 1440 1450
MYADFFDKYE EYKEYIRRKH LREIEAKQKA LGLTVGAGRG LQARDRAMLS
1460 1470 1480 1490 1500
ATKWNAYFNK SRKDERQSCM DLQTFTINQP QPRTAPTCTR LERSTSDLIR
1510 1520 1530 1540 1550
AVAEEANIPA PPNLLPPRDY DEAFRNSDYA YPLTVVPDQF SMAYRQFEPA
1560 1570 1580 1590 1600
ELRAYPLDTA LDKPPTDLMA QLLQAKSEAV GSDEIKTSAP APKDLGQEQS
1610 1620 1630 1640 1650
AIKSVTVTAP VRRSRRSTRQ QTDKVRTASS SSTSSAQSVS SASSGNGSSS
1660 1670 1680 1690 1700
DTESGDESDF SSTSSCSSST GASSGAGSED EDGNECSSSV RLSTCGVCLR
1710 1720 1730 1740 1750
SQHRNARDMP EAFIRCYTCR KRVHPSCVDM PPRMVGRVRN YNWQCAGCKC
1760 1770 1780 1790 1800
CIKCRSSQRP GKMLYCEQCD RGYHIYCLGL RTVPDGRWSC ERCCFCMRCG
1810 1820 1830 1840 1850
ATKPEGLPQV AALSQASGGP SANGDRSKAA RNKRLKWVHE YRIDHVTKIR
1860 1870 1880 1890 1900
EHAAMFCVPC ARNKPAKRQS AAGAAGAAAV TPVLEATSAQ TDDSPMPSPG
1910 1920 1930 1940 1950
LTTNGGRALS PTAALSPKAA VPVASLPPVL EATTVTTNIA GTIGRRQAGN
1960 1970 1980 1990 2000
AVNITTMQCS SSSSSNFSGN GVTEDAANVT ATGTATAAAG APAATPIGIA

PPPVVA
Length:2,006
Mass (Da):212,726
Last modified:July 5, 2004 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1567640FB4E5084
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PI16M9PI16_DROME
Enhancer of yellow 3, isoform C
e(y)3 Dmel\CG12238, e(y)[3], l(1)G0084, l(1)G0266, l(1)G0283
2,012Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PHZ0M9PHZ0_DROME
Enhancer of yellow 3, isoform D
e(y)3 Dmel\CG12238, e(y)[3], l(1)G0084, l(1)G0266, l(1)G0283
2,011Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9PHL0M9PHL0_DROME
Enhancer of yellow 3, isoform B
e(y)3 Dmel\CG12238, e(y)[3], l(1)G0084, l(1)G0266, l(1)G0283
2,006Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAM48352 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48990.3
BT099689 mRNA Translation: ACV44475.1
AY118323 mRNA Translation: AAM48352.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_001259718.1, NM_001272789.1
NP_001259721.1, NM_001272792.1
NP_608334.3, NM_134490.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0074762; FBpp0074531; FBgn0087008
FBtr0334278; FBpp0306393; FBgn0087008
FBtr0334281; FBpp0306396; FBgn0087008

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
32965

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG12238

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48990.3
BT099689 mRNA Translation: ACV44475.1
AY118323 mRNA Translation: AAM48352.1 Different initiation.
RefSeqiNP_001259718.1, NM_001272789.1
NP_001259721.1, NM_001272792.1
NP_608334.3, NM_134490.3

3D structure databases

SMRiQ9VWF2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi59261, 28 interactors
DIPiDIP-48904N
IntActiQ9VWF2, 26 interactors
MINTiQ9VWF2
STRINGi7227.FBpp0074531

Proteomic databases

PaxDbiQ9VWF2
PRIDEiQ9VWF2

Genome annotation databases

EnsemblMetazoaiFBtr0074762; FBpp0074531; FBgn0087008
FBtr0334278; FBpp0306393; FBgn0087008
FBtr0334281; FBpp0306396; FBgn0087008
GeneIDi32965
KEGGidme:Dmel_CG12238

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
32965
FlyBaseiFBgn0087008, e(y)3

Phylogenomic databases

eggNOGiKOG1512, Eukaryota
GeneTreeiENSGT00940000155172
InParanoidiQ9VWF2
OrthoDBi708781at2759
PhylomeDBiQ9VWF2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
32965, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
32965

Protein Ontology

More...
PROi
PR:Q9VWF2

Gene expression databases

BgeeiFBgn0087008, Expressed in embryo and 56 other tissues
ExpressionAtlasiQ9VWF2, baseline and differential
GenevisibleiQ9VWF2, DM

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD
SMARTiView protein in SMART
SM00249, PHD, 2 hits
SUPFAMiSSF57903, SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359, ZF_PHD_1, 2 hits
PS50016, ZF_PHD_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSAYP_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VWF2
Secondary accession number(s): C7LAD9, Q7JW70
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: December 2, 2020
This is version 152 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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