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UniProtKB - Q9VVX6 (Q9VVX6_DROME)
Protein
Submitted name:
Blocked early in transport 1, isoform A
Gene
Bet1
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- SNAP receptor activity Source: FlyBase
- syntaxin binding Source: FlyBase
GO - Biological processi
- endoplasmic reticulum to Golgi vesicle-mediated transport Source: FlyBase
- protein transport Source: UniProtKB-KW
- vesicle fusion with Golgi apparatus Source: GO_Central
- vesicle-mediated transport Source: FlyBase
Keywordsi
Biological process | Protein transportARBA annotation, Transport |
Enzyme and pathway databases
Reactomei | R-DME-204005, COPII-mediated vesicle transport R-DME-6807878, COPI-mediated anterograde transport |
Names & Taxonomyi
Protein namesi | Submitted name: Blocked early in transport 1, isoform AImportedSubmitted name: Blocked early in transport 1, isoform BImportedSubmitted name: RH40423pImported |
Gene namesi | Name:Bet1Imported Synonyms:BcDNA:RH40423Imported, BET1Imported, bs16e01.y1Imported, Dm Bet1Imported, Dmel\CG14084Imported, G14084Imported ORF Names:CG14084Imported, Dmel_CG14084Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0260857, Bet1 |
VEuPathDBi | VectorBase:FBgn0260857 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type IV membrane protein ARBA annotation
Golgi apparatus
- Golgi trans cisterna Source: GO_Central
- integral component of Golgi membrane Source: InterPro
Other locations
- SNARE complex Source: FlyBase
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 96 – 114 | HelicalSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
Golgi apparatusARBA annotation, MembraneExpressioni
Gene expression databases
Bgeei | FBgn0260857, Expressed in saliva-secreting gland and 37 other tissues |
Interactioni
GO - Molecular functioni
- syntaxin binding Source: FlyBase
Protein-protein interaction databases
IntActi | Q9VVX6, 24 interactors |
STRINGi | 7227.FBpp0074758 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 24 – 86 | T-SNARE coiled-coil homologyInterPro annotationAdd BLAST | 63 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 30 | DisorderedSequence analysisAdd BLAST | 30 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 16 | Polar residuesSequence analysisAdd BLAST | 16 |
Keywords - Domaini
Coiled coilPROSITE-ProRule annotationARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG3385, Eukaryota |
GeneTreei | ENSGT00940000163414 |
HOGENOMi | CLU_086133_2_1_1 |
OMAi | DENERMT |
OrthoDBi | 1450835at2759 |
Family and domain databases
CDDi | cd15853, SNARE_Bet1, 1 hit |
InterProi | View protein in InterPro IPR039897, BET1 IPR039899, BET1_SNARE IPR000727, T_SNARE_dom |
PANTHERi | PTHR12791, PTHR12791, 1 hit |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit |
SMARTi | View protein in SMART SM00397, t_SNARE, 1 hit |
PROSITEi | View protein in PROSITE PS50192, T_SNARE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VVX6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRRNNYPYQP LNQHPSGPHP ASHDALEAEN EQAAEELKQK IGALKSLTID
60 70 80 90 100
IGNEVRYQDK LLRGIDDDMD RTSGFLGNAM TRVVRLAKQG GGARQMCYMF
110
LFILVVFLIL WITLKFK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF49180.1 AY113588 mRNA Translation: AAM29593.1 AE014296 Genomic DNA Translation: AAN11658.1 |
RefSeqi | NP_649096.1, NM_140839.4 NP_730391.1, NM_168789.5 |
Genome annotation databases
EnsemblMetazoai | FBtr0074989; FBpp0074757; FBgn0260857 FBtr0074990; FBpp0074758; FBgn0260857 |
GeneIDi | 40094 |
KEGGi | dme:Dmel_CG14084 |
UCSCi | CG14084-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF49180.1 AY113588 mRNA Translation: AAM29593.1 AE014296 Genomic DNA Translation: AAN11658.1 |
RefSeqi | NP_649096.1, NM_140839.4 NP_730391.1, NM_168789.5 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q9VVX6, 24 interactors |
STRINGi | 7227.FBpp0074758 |
Protocols and materials databases
DNASUi | 40094 |
Genome annotation databases
EnsemblMetazoai | FBtr0074989; FBpp0074757; FBgn0260857 FBtr0074990; FBpp0074758; FBgn0260857 |
GeneIDi | 40094 |
KEGGi | dme:Dmel_CG14084 |
UCSCi | CG14084-RA, d. melanogaster |
Organism-specific databases
CTDi | 10282 |
FlyBasei | FBgn0260857, Bet1 |
VEuPathDBi | VectorBase:FBgn0260857 |
Phylogenomic databases
eggNOGi | KOG3385, Eukaryota |
GeneTreei | ENSGT00940000163414 |
HOGENOMi | CLU_086133_2_1_1 |
OMAi | DENERMT |
OrthoDBi | 1450835at2759 |
Enzyme and pathway databases
Reactomei | R-DME-204005, COPII-mediated vesicle transport R-DME-6807878, COPI-mediated anterograde transport |
Miscellaneous databases
BioGRID-ORCSi | 40094, 0 hits in 1 CRISPR screen |
GenomeRNAii | 40094 |
Gene expression databases
Bgeei | FBgn0260857, Expressed in saliva-secreting gland and 37 other tissues |
Family and domain databases
CDDi | cd15853, SNARE_Bet1, 1 hit |
InterProi | View protein in InterPro IPR039897, BET1 IPR039899, BET1_SNARE IPR000727, T_SNARE_dom |
PANTHERi | PTHR12791, PTHR12791, 1 hit |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit |
SMARTi | View protein in SMART SM00397, t_SNARE, 1 hit |
PROSITEi | View protein in PROSITE PS50192, T_SNARE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VVX6_DROME | |
Accessioni | Q9VVX6Primary (citable) accession number: Q9VVX6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | January 19, 2022 | |
This is version 174 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |