Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 174 (10 Feb 2021)
Sequence version 2 (01 Mar 2001)
Previous versions | rss
Add a publicationFeedback
Protein

Solute carrier organic anion transporter family member 74D

Gene

Oatp74D

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transporter that mediates the cellular uptake of ecdysteroids, including ecdysone, from the hemolymph.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-189483, Heme degradation
R-DME-879518, Transport of organic anions

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier organic anion transporter family member 74DCurated
Alternative name(s):
Ecdysone Importer1 Publication
Short name:
EcI1 Publication
Organic anion transporting polypeptide 74DImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Oatp74DImported
ORF Names:CG7571Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0036732, Oatp74D

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 174CytoplasmicCuratedAdd BLAST174
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei175 – 195Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini196 – 213ExtracellularCuratedAdd BLAST18
Transmembranei214 – 234Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini235 – 242CytoplasmicCurated8
Transmembranei243 – 263Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini264 – 332ExtracellularCuratedAdd BLAST69
Transmembranei333 – 353Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini354 – 373CytoplasmicCuratedAdd BLAST20
Transmembranei374 – 394Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini395 – 413ExtracellularCuratedAdd BLAST19
Transmembranei414 – 434Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini435 – 488CytoplasmicCuratedAdd BLAST54
Transmembranei489 – 509Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini510 – 522ExtracellularCuratedAdd BLAST13
Transmembranei523 – 543Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini544 – 553CytoplasmicCurated10
Transmembranei554 – 574Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini575 – 667ExtracellularCuratedAdd BLAST93
Transmembranei668 – 688Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini689 – 707CytoplasmicCuratedAdd BLAST19
Transmembranei708 – 728Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini729 – 756ExtracellularCuratedAdd BLAST28
Transmembranei757 – 777Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini778 – 819CytoplasmicCuratedAdd BLAST42

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Development is arrested at the end of the first instar larval stage (PubMed:30293839). RNAi-mediated knockdown blocks ecdysone-dependent fat body cell migration into the pupal head (PubMed:30293839). In the fat body, results in defective ecdysone signaling (PubMed:30293839).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004465141 – 819Solute carrier organic anion transporter family member 74DAdd BLAST819

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi284N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi293N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi309N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi401N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi599 ↔ 630PROSITE-ProRule annotation
Glycosylationi604N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi607 ↔ 626PROSITE-ProRule annotation
Disulfide bondi616 ↔ 649PROSITE-ProRule annotation
Glycosylationi640N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VVH9

PRoteomics IDEntifications database

More...
PRIDEi
Q9VVH9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed ubiquitously during development in central nervous system, imaginal disk, fat body, gut, and to a lesser extent in Malpighian tubules.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0036732, Expressed in head and 41 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VVH9, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9VVH9, 3 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0074939

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini593 – 651Kazal-likePROSITE-ProRule annotationAdd BLAST59

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the organo anion transporter (TC 2.A.60) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3626, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT01010000222485

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008954_1_3_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
LVMRCTH

Database of Orthologous Groups

More...
OrthoDBi
1029129at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VVH9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002350, Kazal_dom
IPR036259, MFS_trans_sf
IPR004156, OATP

The PANTHER Classification System

More...
PANTHERi
PTHR11388, PTHR11388, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03137, OATP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473, SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00805, oat, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51465, KAZAL_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VVH9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKSNGDVEA AAQVQSLGGK PSNGHGQLNG NGYHQNGGRR DSSQAFTPLL
60 70 80 90 100
SQHNNGTTNG EVTTPPPSTV LYESTPSNNN EWKAPEDLGH LKNGLGNILS
110 120 130 140 150
SNNNGTGNGH SLSEKYAHEQ APLTGGYKLP PRSSESEESD FDSDLNGGSS
160 170 180 190 200
AESSSSCGLF GCRPRWARRF ASTHVFMVVF LLAYILQGMY MTYFVSVITT
210 220 230 240 250
IEKLFQIKSK TTGILLSASE MGQICTAMLL TYFAGRGHRP RWIACGMVLF
260 270 280 290 300
SIAAFSCALP HFIFGEQLMH SSVILQQTQV SPPNNSFSSH WLNASSEQVN
310 320 330 340 350
PNLCILGGNQ THSGSECNEE RQLEQASHSK ITVIVLCIFF GSLLSSGIGQ
360 370 380 390 400
TAVATLGIPY IDDNVGSKQS PMYMAVTIGM RILGPASGFI FGSFCTRWYV
410 420 430 440 450
NFSNPGFDAT DPRWIGAWWL GPVAIGSLML LASIAMFSFP KQLRGKQKPP
460 470 480 490 500
GQTATPAAPV EPEEKPKLKD FPKTVRRQLS NDILMFRTAS CVFHLLPIAG
510 520 530 540 550
LYTFLPKYLE TQFRLATYDA NMIAAFCGIL VMGIGIVISG LFILKRKPTA
560 570 580 590 600
RGVAAWIAFT ALVYSAGMII LMFIGCSMND FAGYKPSDGN SPALIEPTCS
610 620 630 640 650
AALNCTCDKE NFAPICADGK MYISACHAGC SSSSLRPSDN RTLYSDCACI
660 670 680 690 700
PDAPEAVNGY CDNNCKNFIY FILIFAICVF MHSTSEVGSM LLVMRCTHPK
710 720 730 740 750
DKAMAMGVIQ SAIGLFGNVP CPIIYGAVVD SACLIWKSVC GKHGACSLYD
760 770 780 790 800
ADTFRQYFLG ITAGIMFLAF LMDLVVWRKA HRIDIAPEDP QEGGPASNGR
810
TLEVSESKQP ITPAPDTTV
Length:819
Mass (Da):88,506
Last modified:March 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2C33EAF513C0D87C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49332.2
AE014296 Genomic DNA Translation: ACZ94731.1
AE014296 Genomic DNA Translation: AHN58120.1
AE014296 Genomic DNA Translation: AHN58121.1
BT001436 mRNA Translation: AAN71191.1

NCBI Reference Sequences

More...
RefSeqi
NP_001163460.1, NM_001169989.2
NP_001287095.1, NM_001300166.1
NP_001287096.1, NM_001300167.1
NP_648989.1, NM_140732.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0075173; FBpp0074939; FBgn0036732
FBtr0302041; FBpp0291251; FBgn0036732
FBtr0345117; FBpp0311342; FBgn0036732
FBtr0345118; FBpp0311343; FBgn0036732

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
39954

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG7571

UCSC genome browser

More...
UCSCi
CG7571-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49332.2
AE014296 Genomic DNA Translation: ACZ94731.1
AE014296 Genomic DNA Translation: AHN58120.1
AE014296 Genomic DNA Translation: AHN58121.1
BT001436 mRNA Translation: AAN71191.1
RefSeqiNP_001163460.1, NM_001169989.2
NP_001287095.1, NM_001300166.1
NP_001287096.1, NM_001300167.1
NP_648989.1, NM_140732.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9VVH9, 3 interactors
STRINGi7227.FBpp0074939

Proteomic databases

PaxDbiQ9VVH9
PRIDEiQ9VVH9

Genome annotation databases

EnsemblMetazoaiFBtr0075173; FBpp0074939; FBgn0036732
FBtr0302041; FBpp0291251; FBgn0036732
FBtr0345117; FBpp0311342; FBgn0036732
FBtr0345118; FBpp0311343; FBgn0036732
GeneIDi39954
KEGGidme:Dmel_CG7571
UCSCiCG7571-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
39954
FlyBaseiFBgn0036732, Oatp74D

Phylogenomic databases

eggNOGiKOG3626, Eukaryota
GeneTreeiENSGT01010000222485
HOGENOMiCLU_008954_1_3_1
OMAiLVMRCTH
OrthoDBi1029129at2759
PhylomeDBiQ9VVH9

Enzyme and pathway databases

ReactomeiR-DME-189483, Heme degradation
R-DME-879518, Transport of organic anions

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
39954, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
39954

Protein Ontology

More...
PROi
PR:Q9VVH9

Gene expression databases

BgeeiFBgn0036732, Expressed in head and 41 other tissues
ExpressionAtlasiQ9VVH9, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002350, Kazal_dom
IPR036259, MFS_trans_sf
IPR004156, OATP
PANTHERiPTHR11388, PTHR11388, 1 hit
PfamiView protein in Pfam
PF03137, OATP, 1 hit
SUPFAMiSSF103473, SSF103473, 1 hit
TIGRFAMsiTIGR00805, oat, 1 hit
PROSITEiView protein in PROSITE
PS51465, KAZAL_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSO74D_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VVH9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 10, 2019
Last sequence update: March 1, 2001
Last modified: February 10, 2021
This is version 174 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again