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Entry version 130 (16 Jan 2019)
Sequence version 2 (01 Oct 2002)
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Protein
Submitted name:

Uncharacterized protein, isoform A

Gene

Arts

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • nuclear localization sequence binding Source: GO_Central
  • protein transporter activity Source: GO_Central
  • Ran GTPase binding Source: InterPro

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein, isoform AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ArtsImported
Synonyms:CG18219Imported, CG18860Imported, Dmel\CG32164Imported
ORF Names:CG32164Imported, Dmel_CG32164Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0042177 Arts

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9VV82

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0042177 Expressed in 4 organ(s), highest expression level in larva

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VV82 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VV82 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9VV82, 8 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9VV82

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VV82

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini23 – 91Importin N-terminalInterPro annotationAdd BLAST69

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IQKY Eukaryota
ENOG410XP2Z LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00550000075074

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VV82

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VV82

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR001494 Importin-beta_N
IPR040122 Importin_beta

The PANTHER Classification System

More...
PANTHERi
PTHR10527 PTHR10527, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03810 IBN_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00913 IBN_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50166 IMPORTIN_B_NT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VV82-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEAAILDIIN GILAIDTERI RESTAKMLKA YENPDSLLVL TQIVMSDRPV
60 70 80 90 100
QERQVAAVLL KRRVKKLRHW QLVPAEHQAA IKSNMLQVLI AVKEKTVKGT
110 120 130 140 150
VAFIIGSLVR HEEDKQNSWR EEILKFIYER CSSPDPIESE RGSSIFSSLM
160 170 180 190 200
DAAPDQFSNH TDTIFPLLAG ILVTAEANGN MATPTVHNML AGTCVLLPFI
210 220 230 240 250
SGHSDAEQIM VKAVPLILKA LAAFAEKGNS NEFMGAFDII DSMAEYVPHL
260 270 280 290 300
LTGNVKLLLE FCLMIARNKQ FDASIRVQVL TFVGSLVRLK KKIIMKQKLL
310 320 330 340 350
QPTLSVLFEV ICQDDLKEDD DYFSSESLNS PSNAAAQTLD LMALHMVPDK
360 370 380 390 400
FIPPLLDLLE PALQSPEPVL RRSSFICMGV IAEGCSEAIG KKYLEVMLNI
410 420 430 440 450
IKAGVLDSVM FVRTAAFFAL GQFSEFLQPT ICKFAPQILP VLFDYLNQLV
460 470 480 490 500
LELKVGEPDS KHMDRMFYAL ETFCENLDED IVPYLPTLMD RLFGVMEPQN
510 520 530 540 550
SNQMREMALS AIAAVSAAAK ENLMPYFPRI MTVLQGCLVK DCPKEMYSQR
560 570 580 590 600
IQAIDTLAAL CRELGKDNII PLADETMNFC LMMLEDGPDD PEFRRSIYNL
610 620 630 640 650
MSSLSSVVNE SMASVFPKFI DRIMESVISS EDMVPNVSDN AEDDLALVDA
660 670 680 690 700
PDIEIDLEHT DDEDDQDAYL GENDYIVEKE EAILSLKEFA THTGAAFAPY
710 720 730 740 750
LQSAFENVYK MIDHPQGDVR MACIDSICSF ITALHKLDDA AGLKRACEIA
760 770 780 790 800
IPKFAHIMRT DDQVAVVLRM LDVLYDVFKY VPAINSQEHA ELIFGCIRDI
810 820 830 840 850
FTNKMACQFN EESGGGDDEC SEESENDEML FENAANLFPM FGLTLQPELF
860 870 880 890 900
SLYFGRLYHF YIQRLAKVKE RDLPEQRAYI YGALADCCKA LKGCCATYFD
910 920 930 940 950
ALRPIFIAGS RDSDAKARQN SYFALGEIVF HSEEKSFESY PTILQALSEA
960 970 980 990 1000
IVRESVPAAM DNICGAVARL IVTNPDSVPL GQVLPVWLNH LPLKDDTVEN
1010 1020 1030 1040 1050
DVIQKAFRVL YLKARPSIEA HLEQILAITI EASYKKQMPD VETTESAVAL
1060 1070
IKEIRANYPE LFSKVSNMNP EVFNYVQAL
Length:1,079
Mass (Da):120,809
Last modified:October 1, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i70A0351CEBBB87BA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PFR8M9PFR8_DROME
Uncharacterized protein, isoform B
Arts CG18219, CG18860, Dmel\CG32164, CG32164, Dmel_CG32164
1,080Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49437.2

NCBI Reference Sequences

More...
RefSeqi
NP_730184.1, NM_168677.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Dm.1565

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0075313; FBpp0075073; FBgn0042177

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
59215

UCSC genome browser

More...
UCSCi
CG32164-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49437.2
RefSeqiNP_730184.1, NM_168677.2
UniGeneiDm.1565

3D structure databases

ProteinModelPortaliQ9VV82
SMRiQ9VV82
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9VV82, 8 interactors

Proteomic databases

PRIDEiQ9VV82

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0075313; FBpp0075073; FBgn0042177
GeneIDi59215
UCSCiCG32164-RA d. melanogaster

Organism-specific databases

FlyBaseiFBgn0042177 Arts

Phylogenomic databases

eggNOGiENOG410IQKY Eukaryota
ENOG410XP2Z LUCA
GeneTreeiENSGT00550000075074
InParanoidiQ9VV82
PhylomeDBiQ9VV82

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
59215

Gene expression databases

BgeeiFBgn0042177 Expressed in 4 organ(s), highest expression level in larva
ExpressionAtlasiQ9VV82 baseline and differential
GenevisibleiQ9VV82 DM

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR001494 Importin-beta_N
IPR040122 Importin_beta
PANTHERiPTHR10527 PTHR10527, 1 hit
PfamiView protein in Pfam
PF03810 IBN_N, 1 hit
SMARTiView protein in SMART
SM00913 IBN_N, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50166 IMPORTIN_B_NT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VV82_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VV82
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: October 1, 2002
Last modified: January 16, 2019
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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