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Entry version 148 (11 Dec 2019)
Sequence version 1 (01 May 2000)
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Protein

Phosphoglucomutase

Gene

Pgm1

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This enzyme participates in both the breakdown and synthesis of glucose.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+1 PublicationNote: Binds 1 Mg2+ ion per subunit.1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=140 µM for glucose-1-phosphate (for Pgm-A at pH 6.0)1 Publication
  2. KM=158 µM for glucose-1-phosphate (for Pgm-A at pH 7.4)1 Publication
  3. KM=4.4 µM for glucose-1,6-diphosphate (for Pgm-A at pH 6.0)1 Publication
  4. KM=4.4 µM for glucose-1,6-diphosphate (for Pgm-A at pH 7.4)1 Publication
  5. KM=142.2 µM for glucose-1-phosphate (for Pgm-B at pH 6.0)1 Publication
  6. KM=112.4 µM for glucose-1-phosphate (for Pgm-B at pH 7.4)1 Publication
  7. KM=21.7 µM for glucose-1,6-diphosphate (for Pgm-B at pH 6.0)1 Publication
  8. KM=4.2 µM for glucose-1,6-diphosphate (for Pgm-B at pH 7.4)1 Publication
  1. Vmax=32.8 µmol/min/mg enzyme toward glucose-1-phosphate (for Pgm-A at pH 6.0)1 Publication
  2. Vmax=129 µmol/min/mg enzyme toward glucose-1-phosphate (for Pgm-A at pH 7.4)1 Publication
  3. Vmax=20.8 µmol/min/mg enzyme toward glucose-1,6-diphosphate (for Pgm-A at pH 6.0)1 Publication
  4. Vmax=111 µmol/min/mg enzyme toward glucose-1,6-diphosphate (for Pgm-A at pH 7.4)1 Publication
  5. Vmax=35 µmol/min/mg enzyme toward glucose-1-phosphate (for Pgm-B at pH 6.0)1 Publication
  6. Vmax=120.9 µmol/min/mg enzyme toward glucose-1-phosphate (for Pgm-B at pH 7.4)1 Publication
  7. Vmax=14.5 µmol/min/mg enzyme toward glucose-1,6-diphosphate (for Pgm-B at pH 6.0)1 Publication
  8. Vmax=100 µmol/min/mg enzyme toward glucose-1,6-diphosphate (for Pgm-B at pH 7.4)1 Publication

pH dependencei

Optimum pH is 7.4-7.6.1 Publication

Temperature dependencei

Pgm-A is more thermostable than Pgm-B.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei20SubstrateBy similarity1
Binding sitei24SubstrateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei116Phosphoserine intermediateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi116Magnesium; via phosphate groupBy similarity1
Binding sitei129SubstrateBy similarity1
Metal bindingi288MagnesiumBy similarity1
Metal bindingi290MagnesiumBy similarity1
Metal bindingi292MagnesiumBy similarity1
Binding sitei357SubstrateBy similarity1
Binding sitei389SubstrateBy similarity1
Binding sitei515SubstrateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • galactose catabolic process Source: GO_Central
  • glucose metabolic process Source: GO_Central
  • glycogen biosynthetic process Source: FlyBase

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Glucose metabolism
LigandMagnesium, Metal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-3322077 Glycogen synthesis
R-DME-6798695 Neutrophil degranulation

SABIO-RK: Biochemical Reaction Kinetics Database

More...
SABIO-RKi
Q9VUY9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphoglucomutase (EC:5.4.2.2)
Short name:
PGM
Alternative name(s):
Glucose phosphomutase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pgm1Imported
ORF Names:CG5165Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0003076 Pgm1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001477891 – 560PhosphoglucomutaseAdd BLAST560

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei116Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VUY9

PRoteomics IDEntifications database

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PRIDEi
Q9VUY9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9VUY9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Localized primarily to fat bodies in third instar larvae.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0003076 Expressed in 32 organ(s), highest expression level in capitellum (Drosophila)

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VUY9 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
68773, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VUY9, 7 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0075247

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VUY9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni116 – 117Substrate bindingBy similarity2
Regioni292 – 293Substrate bindingBy similarity2
Regioni376 – 378Substrate bindingBy similarity3

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the phosphohexose mutase family.1 Publication

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0625 Eukaryota
COG0033 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000173602

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9VUY9

KEGG Orthology (KO)

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KOi
K01835

Identification of Orthologs from Complete Genome Data

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OMAi
DIYKIYA

Database of Orthologous Groups

More...
OrthoDBi
555015at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VUY9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005844 A-D-PHexomutase_a/b/a-I
IPR016055 A-D-PHexomutase_a/b/a-I/II/III
IPR005845 A-D-PHexomutase_a/b/a-II
IPR005846 A-D-PHexomutase_a/b/a-III
IPR005843 A-D-PHexomutase_C
IPR036900 A-D-PHexomutase_C_sf
IPR016066 A-D-PHexomutase_CS
IPR005841 Alpha-D-phosphohexomutase_SF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02878 PGM_PMM_I, 1 hit
PF02879 PGM_PMM_II, 1 hit
PF02880 PGM_PMM_III, 1 hit
PF00408 PGM_PMM_IV, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00509 PGMPMM

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53738 SSF53738, 3 hits
SSF55957 SSF55957, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00710 PGM_PMM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VUY9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLTVEIVAT KPYEGQKPGT SGLRKKVKVF TQPNYTENFV QAILEANGAA
60 70 80 90 100
LAGSTLVVGG DGRFYCKEAA ELIVRLSAAN GVSKLLVGQN GILSTPAVSS
110 120 130 140 150
LIRHNKALGG IVLTASHNPG GPENDFGIKF NCENGGPAPD AFTNHIYKIT
160 170 180 190 200
TEIKEYKLVR NLQIDISKVG VTSFDIAGKP FTVEVIDSVA NYVRHMEEIF
210 220 230 240 250
DFAKLKDFVS GKATGKPLKM RIDAMNGVTG SYVREIFLNR LGATESSVVH
260 270 280 290 300
TTPLPDFGGL HPDPNLTYAK DLVDTVAQGD YDIGAAFDGD GDRNMIIGSK
310 320 330 340 350
AFFVTPSDSL AVIAHYLEAI PYFQKNGVQG FARSMPTASA VDLVGRKLGK
360 370 380 390 400
EVFEVPTGWK YFGNLMDAGR LCLCGEESFG TGSNHIREKD GIWAVLAWIS
410 420 430 440 450
VMQHTGKGIE DILKQHWSVY GRNYFTRYDY EECASDPCNE MVATMEKTIT
460 470 480 490 500
APEFVGKSYS SGGKTYKVKE ADNFSYTDPV DKSVATKQGL RIVFEDGSRI
510 520 530 540 550
VVRLSGTGSS GATVRLYIDS YEKENVLGQA SVMLKPLIDI ALEISQLPKF
560
TGRNAPTVIT
Length:560
Mass (Da):60,766
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i10320D78D41C1BEC
GO

<p>This subsection of the ‘Sequence’ section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

The polymorphisms show clinal variations. There are 2 common electrophoretic variants, Pgm-A and Pgm-B, which differ in their kinetic and stability parameters. Variations in Pgm are associated with differences in enzyme activity and glycogen content.

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti6E → G1 Publication1
Natural varianti9A → T in strain: dpf95_94.1 and zim_26H. 4 Publications1
Natural varianti17K → Q1 Publication1
Natural varianti28K → N1 Publication1
Natural varianti36T → M2 Publications1
Natural varianti50A → V in strain: zim_38H. 1 Publication1
Natural varianti52A → I in strain: zim_36H. 2 Publications1
Natural varianti52A → V in strain: dpf95_48.2, dpf95_100.3 and hfl97_93.0. 2 Publications1
Natural varianti64F → Y in strain: zim_36H. 1 Publication1
Natural varianti109G → A in strain: B4039. 1 Publication1
Natural varianti197E → K in strain: dpf95_56.1. 2 Publications1
Natural varianti235E → K in strain: dpf95_13.0. 2 Publications1
Natural varianti240R → L in strain: dpf95_38.3 and dpf95_4.2. 4 Publications1
Natural varianti245E → D in strain: dpf95_38.3 and dpf95_4.2. 4 Publications1
Natural varianti338A → S in strain: dpf95_36.4. 2 Publications1
Natural varianti341V → M in strain: B4039, dpf95_77.4 and dpf95_90.2. 3 Publications1
Natural varianti346R → K in strain: dpf95_90.2, hfl97_1.0, hfl97_13.0, hfl97_15.0, hfl97_50.0, md90_709.1, zim_36H and zim_39H. 2 Publications1
Natural varianti351E → K1 Publication1
Natural varianti465T → S in strain: dpf95_29.3. 3 Publications1
Natural varianti484V → L in strain: dpf95_38.3, dpf95_4.2, dpf95_44.3, dpf95_48.2, dpf95_53.1, dpf95_56.1, dpf95_85.1, hfl97_1.0, hfl97_13.0, hfl97_15.0, hfl97_50.0, hfl97_93.0, md90_709.1, zim_11S, zim_23H, zim_35S, zim_36H, zim_38H, zim_39H, zim_44H, zim_48S and zim_49S. 3 Publications1
Natural varianti530A → T in strain: dpf95_44.3, dpf95_53.1 and dpf95_85.1. 3 Publications1
Natural varianti540I → F in strain: zim_48S. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF290313 Genomic DNA Translation: AAG44900.1
AF290314 Genomic DNA Translation: AAG44901.1
AF290315 Genomic DNA Translation: AAG44902.1
AF290316 Genomic DNA Translation: AAG44903.1
AF290317 Genomic DNA Translation: AAG44904.1
AF290318 Genomic DNA Translation: AAG44905.1
AF290319 Genomic DNA Translation: AAG44906.1
AF290320 Genomic DNA Translation: AAG44907.1
AF290321 Genomic DNA Translation: AAG44908.1
AF290322 Genomic DNA Translation: AAG44909.1
AF290323 Genomic DNA Translation: AAG44910.1
AF290324 Genomic DNA Translation: AAG44911.1
AF290325 Genomic DNA Translation: AAG44912.1
AF290326 Genomic DNA Translation: AAG44913.1
AF290327 Genomic DNA Translation: AAG44914.1
AF290328 Genomic DNA Translation: AAG44915.1
AF290329 Genomic DNA Translation: AAG44916.1
AF290330 Genomic DNA Translation: AAG44917.1
AF290331 Genomic DNA Translation: AAG44918.1
AF290332 Genomic DNA Translation: AAG44919.1
AF290333 Genomic DNA Translation: AAG44920.1
AF290334 Genomic DNA Translation: AAG44921.1
AF290335 Genomic DNA Translation: AAG44922.1
AF290336 Genomic DNA Translation: AAG44923.1
AF290337 Genomic DNA Translation: AAG44924.1
AF290338 Genomic DNA Translation: AAG44925.1
AF290339 Genomic DNA Translation: AAG44926.1
AF290340 Genomic DNA Translation: AAG44927.1
AF290341 Genomic DNA Translation: AAG44928.1
AF290342 Genomic DNA Translation: AAG44929.1
AF290343 Genomic DNA Translation: AAG44930.1
AF290344 Genomic DNA Translation: AAG44931.1
AF290345 Genomic DNA Translation: AAG44932.1
AF290346 Genomic DNA Translation: AAG44933.1
AF290347 Genomic DNA Translation: AAG44934.1
AF290348 Genomic DNA Translation: AAG44935.1
AF290349 Genomic DNA Translation: AAG44936.1
AF290350 Genomic DNA Translation: AAG44937.1
AF290351 Genomic DNA Translation: AAG44938.1
AF290352 Genomic DNA Translation: AAG44939.1
AF290353 Genomic DNA Translation: AAG44940.1
AF290354 Genomic DNA Translation: AAG44941.1
AF290355 Genomic DNA Translation: AAG44942.1
AF290356 Genomic DNA Translation: AAG44943.1
AF416981 mRNA Translation: AAL08565.1
AF416982 mRNA Translation: AAL08566.1
AF416983 mRNA Translation: AAL08567.1
AF416984 mRNA Translation: AAL08568.1
AE014296 Genomic DNA Translation: AAF49533.1
BT010043 mRNA Translation: AAQ22512.1

NCBI Reference Sequences

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RefSeqi
NP_524675.1, NM_079936.3

Genome annotation databases

Ensembl metazoan genome annotation project

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EnsemblMetazoai
FBtr0075492; FBpp0075247; FBgn0003076

Database of genes from NCBI RefSeq genomes

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GeneIDi
44010

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5165

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF290313 Genomic DNA Translation: AAG44900.1
AF290314 Genomic DNA Translation: AAG44901.1
AF290315 Genomic DNA Translation: AAG44902.1
AF290316 Genomic DNA Translation: AAG44903.1
AF290317 Genomic DNA Translation: AAG44904.1
AF290318 Genomic DNA Translation: AAG44905.1
AF290319 Genomic DNA Translation: AAG44906.1
AF290320 Genomic DNA Translation: AAG44907.1
AF290321 Genomic DNA Translation: AAG44908.1
AF290322 Genomic DNA Translation: AAG44909.1
AF290323 Genomic DNA Translation: AAG44910.1
AF290324 Genomic DNA Translation: AAG44911.1
AF290325 Genomic DNA Translation: AAG44912.1
AF290326 Genomic DNA Translation: AAG44913.1
AF290327 Genomic DNA Translation: AAG44914.1
AF290328 Genomic DNA Translation: AAG44915.1
AF290329 Genomic DNA Translation: AAG44916.1
AF290330 Genomic DNA Translation: AAG44917.1
AF290331 Genomic DNA Translation: AAG44918.1
AF290332 Genomic DNA Translation: AAG44919.1
AF290333 Genomic DNA Translation: AAG44920.1
AF290334 Genomic DNA Translation: AAG44921.1
AF290335 Genomic DNA Translation: AAG44922.1
AF290336 Genomic DNA Translation: AAG44923.1
AF290337 Genomic DNA Translation: AAG44924.1
AF290338 Genomic DNA Translation: AAG44925.1
AF290339 Genomic DNA Translation: AAG44926.1
AF290340 Genomic DNA Translation: AAG44927.1
AF290341 Genomic DNA Translation: AAG44928.1
AF290342 Genomic DNA Translation: AAG44929.1
AF290343 Genomic DNA Translation: AAG44930.1
AF290344 Genomic DNA Translation: AAG44931.1
AF290345 Genomic DNA Translation: AAG44932.1
AF290346 Genomic DNA Translation: AAG44933.1
AF290347 Genomic DNA Translation: AAG44934.1
AF290348 Genomic DNA Translation: AAG44935.1
AF290349 Genomic DNA Translation: AAG44936.1
AF290350 Genomic DNA Translation: AAG44937.1
AF290351 Genomic DNA Translation: AAG44938.1
AF290352 Genomic DNA Translation: AAG44939.1
AF290353 Genomic DNA Translation: AAG44940.1
AF290354 Genomic DNA Translation: AAG44941.1
AF290355 Genomic DNA Translation: AAG44942.1
AF290356 Genomic DNA Translation: AAG44943.1
AF416981 mRNA Translation: AAL08565.1
AF416982 mRNA Translation: AAL08566.1
AF416983 mRNA Translation: AAL08567.1
AF416984 mRNA Translation: AAL08568.1
AE014296 Genomic DNA Translation: AAF49533.1
BT010043 mRNA Translation: AAQ22512.1
RefSeqiNP_524675.1, NM_079936.3

3D structure databases

SMRiQ9VUY9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi68773, 6 interactors
IntActiQ9VUY9, 7 interactors
STRINGi7227.FBpp0075247

PTM databases

iPTMnetiQ9VUY9

Proteomic databases

PaxDbiQ9VUY9
PRIDEiQ9VUY9

Genome annotation databases

EnsemblMetazoaiFBtr0075492; FBpp0075247; FBgn0003076
GeneIDi44010
KEGGidme:Dmel_CG5165

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5236
FlyBaseiFBgn0003076 Pgm1

Phylogenomic databases

eggNOGiKOG0625 Eukaryota
COG0033 LUCA
GeneTreeiENSGT00940000173602
InParanoidiQ9VUY9
KOiK01835
OMAiDIYKIYA
OrthoDBi555015at2759
PhylomeDBiQ9VUY9

Enzyme and pathway databases

ReactomeiR-DME-3322077 Glycogen synthesis
R-DME-6798695 Neutrophil degranulation
SABIO-RKiQ9VUY9

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Pgm fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
44010

Protein Ontology

More...
PROi
PR:Q9VUY9

Gene expression databases

BgeeiFBgn0003076 Expressed in 32 organ(s), highest expression level in capitellum (Drosophila)
GenevisibleiQ9VUY9 DM

Family and domain databases

InterProiView protein in InterPro
IPR005844 A-D-PHexomutase_a/b/a-I
IPR016055 A-D-PHexomutase_a/b/a-I/II/III
IPR005845 A-D-PHexomutase_a/b/a-II
IPR005846 A-D-PHexomutase_a/b/a-III
IPR005843 A-D-PHexomutase_C
IPR036900 A-D-PHexomutase_C_sf
IPR016066 A-D-PHexomutase_CS
IPR005841 Alpha-D-phosphohexomutase_SF
PfamiView protein in Pfam
PF02878 PGM_PMM_I, 1 hit
PF02879 PGM_PMM_II, 1 hit
PF02880 PGM_PMM_III, 1 hit
PF00408 PGM_PMM_IV, 1 hit
PRINTSiPR00509 PGMPMM
SUPFAMiSSF53738 SSF53738, 3 hits
SSF55957 SSF55957, 1 hit
PROSITEiView protein in PROSITE
PS00710 PGM_PMM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPGM_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VUY9
Secondary accession number(s): Q95VC1
, Q9GN12, Q9GN65, Q9GN80, Q9GN99, Q9GNA0, Q9GNH5, Q9GNJ1, Q9GQ71, Q9GQ72, Q9GQ73, Q9GQ74, Q9GQ75, Q9GQ76, Q9GQ77, Q9GQ78, Q9GQ79, Q9GQ80
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: May 1, 2000
Last modified: December 11, 2019
This is version 148 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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