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Entry version 160 (05 Jun 2019)
Sequence version 3 (05 Jul 2004)
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Protein

E3 ubiquitin-protein ligase mind-bomb

Gene

mib1

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta (Dl) and Serrate (Ser) receptors, which act as ligands of Notch proteins. Positively regulates the Notch signaling by ubiquitinating the intracellular domain of Dl and Ser, leading to endocytosis of Dl and Ser receptors. Regulates a subset of Notch signaling events, including wing margin specification, leg segmentation and vein determination, that are distinct from those events requiring neuralize (neur) activity. Also modulates lateral inhibition, a neur- and Dl-dependent signaling event, suggesting a distinct but partially complementary function with neur.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.27

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri173 – 220ZZ-typePROSITE-ProRule annotationAdd BLAST48
Zinc fingeri970 – 1005RING-type 1PROSITE-ProRule annotationAdd BLAST36
Zinc fingeri1017 – 1052RING-type 2PROSITE-ProRule annotationAdd BLAST36
Zinc fingeri1183 – 1216RING-type 3PROSITE-ProRule annotationAdd BLAST34

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processNotch signaling pathway, Ubl conjugation pathway
LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9VUX2

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
E3 ubiquitin-protein ligase mind-bomb (EC:2.3.2.27)
Alternative name(s):
Mind bomb homolog
Short name:
D-mib
RING-type E3 ubiquitin transferase mind-bombCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mib1
Synonyms:mind-bomb
ORF Names:CG5841
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0263601 mib1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi457V → M in D-mib4; induces defects in Notch signaling. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000559511 – 1226E3 ubiquitin-protein ligase mind-bombAdd BLAST1226

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VUX2

PRoteomics IDEntifications database

More...
PRIDEi
Q9VUX2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous in the wing imaginal disk (at protein level).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0263601 Expressed in 31 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VUX2 differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VUX2 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with intracellular domain of Dl and Ser.1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
65061, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VUX2, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0075275

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VUX2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini100 – 168MIB/HERC2 1PROSITE-ProRule annotationAdd BLAST69
Domaini237 – 315MIB/HERC2 2PROSITE-ProRule annotationAdd BLAST79
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati567 – 596ANK 1Add BLAST30
Repeati600 – 629ANK 2Add BLAST30
Repeati633 – 662ANK 3Add BLAST30
Repeati666 – 695ANK 4Add BLAST30
Repeati699 – 731ANK 5Add BLAST33
Repeati735 – 765ANK 6Add BLAST31
Repeati769 – 798ANK 7Add BLAST30
Repeati802 – 833ANK 8Add BLAST32

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1159 – 1181Sequence analysisAdd BLAST23

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri173 – 220ZZ-typePROSITE-ProRule annotationAdd BLAST48
Zinc fingeri970 – 1005RING-type 1PROSITE-ProRule annotationAdd BLAST36
Zinc fingeri1017 – 1052RING-type 2PROSITE-ProRule annotationAdd BLAST36
Zinc fingeri1183 – 1216RING-type 3PROSITE-ProRule annotationAdd BLAST34

Keywords - Domaini

ANK repeat, Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0504 Eukaryota
KOG4582 Eukaryota
COG0666 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156781

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VUX2

KEGG Orthology (KO)

More...
KOi
K10645

Database of Orthologous Groups

More...
OrthoDBi
220300at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VUX2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 2 hits
cd02339 ZZ_Mind_bomb, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 2 hits
2.30.30.920, 2 hits
3.30.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR042056 MIB1/2_ZZ
IPR010606 Mib_Herc2
IPR037252 Mib_Herc2_sf
IPR040847 SH3_15
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR000433 Znf_ZZ

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 2 hits
PF06701 MIB_HERC2, 2 hits
PF18346 SH3_15, 2 hits
PF00569 ZZ, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 8 hits
SM00184 RING, 3 hits
SM00291 ZnF_ZZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF159034 SSF159034, 2 hits
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 6 hits
PS51416 MIB_HERC2, 2 hits
PS50089 ZF_RING_2, 3 hits
PS01357 ZF_ZZ_1, 1 hit
PS50135 ZF_ZZ_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9VUX2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSCAATLSSA KDSTNANASG GGGGGGGGGA PTNSNTNTNT NTQSTAVGVV
60 70 80 90 100
VSSAAGTGVG VGGGGGGGGS LPGGTTSSSS ASAAGGVAAG GGGNSAAALV
110 120 130 140 150
RRFSMEGVGA RVIRGPDWKW NKQDGGEGHV GTVRNFESAE EVVVVWDNGT
160 170 180 190 200
AANYRCAGAY DLRILDSAPT GVKHEGTMCD TCRQQPIFGI RWKCAECINY
210 220 230 240 250
DLCSICYHGD KHHLRHRFYR ITTPGGERTM LEPRRKSKKV LARGIFPGAR
260 270 280 290 300
VVRGVDWQWE DQDGGVGRRG KVNEIQDWSS ASPRSAAYVI WDNGSKNLYR
310 320 330 340 350
VGFEGMADLK VVNDAKGSNV YRDHLPLLGE NGPGKGPHGF QIGDKVTVDL
360 370 380 390 400
DLEIVQSLQH GHGGWTDGMF ECLSNAGMVV GIDEDHDIVV AYNSGNRWTF
410 420 430 440 450
NPAVLTKVSS PTTAPPEFQV GDIVKICSDV ESIKILQRGH GEWADAMQLT
460 470 480 490 500
LGKIGRVQQV YHDNDLKVEV GNTSWTYNPL AVCKVASSTA SDGSCAPVIP
510 520 530 540 550
SSERLSAILK KLFEPNVSGD ATEEFVKAAA NGFAARCEEY LAGAAQPSTS
560 570 580 590 600
SASPSSGPDV NVNGVFAGHT ALQAASQNGH IEVIQVLLRH AVDVEIEDKD
610 620 630 640 650
GDRAVHHAAF GDEAAVIEIL AKAGADLNAR NKRRQTSLHI AVNKGHLNVV
660 670 680 690 700
KTLLTLGCHP SLQDSEGDTP LHDAISKEHD EMLSLLLDFG ADITLNNNNG
710 720 730 740 750
FNALHHAALK GNPSAMKILL TKTNRPWIVE EKKDDGYTAL HLAALNNHVE
760 770 780 790 800
IAELLVHMGK ANMDRQNVNL QTALHLAVER QHVQIVKLLV QDGADLNIPD
810 820 830 840 850
KDGDTPLHEA LRHHTLSQLK QLQDVEGFGK LLMGLRNANN KKASASIACF
860 870 880 890 900
LAANGADLTL KNRKQQTPLD LCPDPNLCKT LVKCYNERKT DDSELPGNVA
910 920 930 940 950
GTSSSARARA ASGSLNQSSS VNMPLSSLAA SSTFPAASSS SIFALNGIAN
960 970 980 990 1000
EMSQSLHEDP PKSSASLDEC LVCSDAKRDT VFKPCGHVSC CETCAPRVKK
1010 1020 1030 1040 1050
CLICRETVSS REKIDECLVC SDRRAAVFFR PCGHMVACEH CSALMKKCVL
1060 1070 1080 1090 1100
CRTQIDEILS FSLCCGGSGR PEKVSVAAGA MATVGLPLPD DRFMEAAAAA
1110 1120 1130 1140 1150
ACANASGHSV AMNNTVVTPV AGSSNQLNSQ NNLLAAAAAS SNVSNLSAAG
1160 1170 1180 1190 1200
NAMVAPSNVN NFQMDDVQKL KQQLQDIKEQ TMCPVCFDRI KNMVFLCGHG
1210 1220
TCQMCGDQIE GCPICRKTVE KRILLF
Length:1,226
Mass (Da):129,872
Last modified:July 5, 2004 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA6D9212DC22211B8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M9PI73M9PI73_DROME
Mind bomb 1, isoform B
mib1 2, D-mib, D-mib1, Dmel\CG5841, Dmib
1,115Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49551.3
AY118647 mRNA Translation: AAM50016.1

NCBI Reference Sequences

More...
RefSeqi
NP_648826.2, NM_140569.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0075520; FBpp0075275; FBgn0263601

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
39750

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5841

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49551.3
AY118647 mRNA Translation: AAM50016.1
RefSeqiNP_648826.2, NM_140569.2

3D structure databases

SMRiQ9VUX2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi65061, 7 interactors
IntActiQ9VUX2, 1 interactor
STRINGi7227.FBpp0075275

Proteomic databases

PaxDbiQ9VUX2
PRIDEiQ9VUX2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0075520; FBpp0075275; FBgn0263601
GeneIDi39750
KEGGidme:Dmel_CG5841

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57534
FlyBaseiFBgn0263601 mib1

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
KOG4582 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00940000156781
InParanoidiQ9VUX2
KOiK10645
OrthoDBi220300at2759
PhylomeDBiQ9VUX2

Enzyme and pathway databases

UniPathwayiUPA00143
SignaLinkiQ9VUX2

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
mib1 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
39750

Protein Ontology

More...
PROi
PR:Q9VUX2

Gene expression databases

BgeeiFBgn0263601 Expressed in 31 organ(s), highest expression level in embryo
ExpressionAtlasiQ9VUX2 differential
GenevisibleiQ9VUX2 DM

Family and domain databases

CDDicd00204 ANK, 2 hits
cd02339 ZZ_Mind_bomb, 1 hit
Gene3Di1.25.40.20, 2 hits
2.30.30.920, 2 hits
3.30.40.10, 3 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR042056 MIB1/2_ZZ
IPR010606 Mib_Herc2
IPR037252 Mib_Herc2_sf
IPR040847 SH3_15
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR000433 Znf_ZZ
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF06701 MIB_HERC2, 2 hits
PF18346 SH3_15, 2 hits
PF00569 ZZ, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 8 hits
SM00184 RING, 3 hits
SM00291 ZnF_ZZ, 1 hit
SUPFAMiSSF159034 SSF159034, 2 hits
SSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 6 hits
PS51416 MIB_HERC2, 2 hits
PS50089 ZF_RING_2, 3 hits
PS01357 ZF_ZZ_1, 1 hit
PS50135 ZF_ZZ_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMIB_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VUX2
Secondary accession number(s): Q8MSR3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 5, 2004
Last modified: June 5, 2019
This is version 160 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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