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Entry version 152 (12 Aug 2020)
Sequence version 4 (01 Mar 2003)
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Protein

Putative U5 small nuclear ribonucleoprotein 200 kDa helicase

Gene

l(3)72Ab

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative RNA helicase involved in the second step of RNA splicing.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi503 – 510ATPPROSITE-ProRule annotation8
Nucleotide bindingi1350 – 1357ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • RNA binding Source: GO_Central
  • RNA helicase activity Source: FlyBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicase, Hydrolase
Biological processmRNA processing, mRNA splicing
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-72163, mRNA Splicing - Major Pathway
R-DME-72165, mRNA Splicing - Minor Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative U5 small nuclear ribonucleoprotein 200 kDa helicase (EC:3.6.4.13)
Alternative name(s):
Protein lethal (3) 72Ab
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CG5931
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0263599, l(3)72Ab

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus, Spliceosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001020891 – 2142Putative U5 small nuclear ribonucleoprotein 200 kDa helicaseAdd BLAST2142

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VUV9

PRoteomics IDEntifications database

More...
PRIDEi
Q9VUV9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0263599, Expressed in embryo and 38 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VUV9, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
65049, 18 interactors

Protein interaction database and analysis system

More...
IntActi
Q9VUV9, 7 interactors

Molecular INTeraction database

More...
MINTi
Q9VUV9

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0075282

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VUV9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini490 – 673Helicase ATP-binding 1PROSITE-ProRule annotationAdd BLAST184
Domaini684 – 917Helicase C-terminal 1PROSITE-ProRule annotationAdd BLAST234
Domaini981 – 1286SEC63 1Add BLAST306
Domaini1337 – 1511Helicase ATP-binding 2PROSITE-ProRule annotationAdd BLAST175
Domaini1544 – 1752Helicase C-terminal 2PROSITE-ProRule annotationAdd BLAST209
Domaini1811 – 2128SEC63 2Add BLAST318

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi615 – 618DEIH box4
Motifi1453 – 1456DELQ box4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi396 – 399Poly-Ala4

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Composed of two similar domains.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the helicase family. SKI2 subfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0951, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154966

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000335_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VUV9

KEGG Orthology (KO)

More...
KOi
K12854

Identification of Orthologs from Complete Genome Data

More...
OMAi
KKMENWW

Database of Orthologous Groups

More...
OrthoDBi
154891at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VUV9

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041094, Brr2_helicase_PWI
IPR035892, C2_domain_sf
IPR011545, DEAD/DEAH_box_helicase_dom
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR014756, Ig_E-set
IPR027417, P-loop_NTPase
IPR004179, Sec63-dom
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00270, DEAD, 2 hits
PF00271, Helicase_C, 1 hit
PF18149, Helicase_PWI, 1 hit
PF02889, Sec63, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487, DEXDc, 2 hits
SM00490, HELICc, 2 hits
SM00973, Sec63, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 2 hits
SSF52540, SSF52540, 4 hits
SSF81296, SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 2 hits
PS51194, HELICASE_CTER, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VUV9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADAAARQLQ YEYKANSNLV LQADVRLIER PRRDEATGEV CSLVGKLDGT
60 70 80 90 100
RMGDRYQRTK PEKTEERKVK RQKRDEAQYD FERMKGATLL SEGIDEMVGI
110 120 130 140 150
VYRPKTQETR QTYEVLLSFI QEALGDQPRD ILCGAADEIL AVLKNDRLKD
160 170 180 190 200
RERKKDIDSL LGAVTDERFA LLVNLGKKIT DFGSDAVNAL TAAPNNEEQI
210 220 230 240 250
DETYGINVQF EESEEESDND MYGEIRDDDA QDEGEEARID HTLHAENLAN
260 270 280 290 300
EEAANNVKKE RSLHPLDIDA YWLQRCLSKF YKDAMVSQSK AADVLKILKD
310 320 330 340 350
AADDRDCENQ LVLLLGYDCF DFIKQLKLNR QMVLYCTMLA SAQTDSERQR
360 370 380 390 400
IREKMRGNSA LAKILRQLDT GKSEDQEEGE ARGSKRGKGD AEDGGAAAAG
410 420 430 440 450
QVAGVRQLLE LEEMAFTQGS HFMANKRCQL PDGSYRKQRK GYEEVHVPAL
460 470 480 490 500
KPVPFDANEE LQPVDKLPKY VQPVFEGFKT LNRIQSRLYK AALDSDENML
510 520 530 540 550
LCAPTGAGKT NVALLTMMRE IGKHINEDGT INAQDFKIIY VAPMKSLVQE
560 570 580 590 600
MVGNFGRRLA CYNLTVSELT GDHQLTREQI AATQVIVCTP EKWDIITRKG
610 620 630 640 650
GERTFVSLVR LVIIDEIHLL HDERGPVLEA LVARTIRNIE TTQEEVRLVG
660 670 680 690 700
LSATLPNYQD VATFLRVKPD KGLFYFDNSY RPVSLEQQYI GVTEKKALKR
710 720 730 740 750
FQVMNEIVYE KTMEHAGRNQ VLVFVHSRKE TGKTARAVRD MCLEQDTLGS
760 770 780 790 800
FLKEGSASME VLRTEAEQVK NTELKELLPY GFAIHHAGMT RVDRTLVEDL
810 820 830 840 850
FADRHIQVLV STATLAWGVN LPAHTVIIKG TQVYNPEKGR WVELSALDVL
860 870 880 890 900
QMLGRAGRPQ YDTKGEGILI TNHSELQFYL SLLNQQLPIE SQFISKLPDM
910 920 930 940 950
LNAEIVLGTV QHLQDAVNWL GYTYLYIRML RNPTLYGVSH DAIKADPLLE
960 970 980 990 1000
QHRADLLHTA ACCLERSGLI KYDRKTGHFQ VTDLGRIASH YYLTHETMLT
1010 1020 1030 1040 1050
YNQLLKQTLS EIELFRVFSL SSEFRHISVR EEEKLELQKL MERVPIPIKE
1060 1070 1080 1090 1100
SIEEHSAKVN VLLQAYISQL KLEGFALMSD MVFITQSAAR LMRAIFEIVL
1110 1120 1130 1140 1150
TRGWAQLADK TLTLCKMIDR RMWQSMTPLR QFKKMPDEIA KKLEKKHFPW
1160 1170 1180 1190 1200
GRLYDLEPHE LGELIRVPKL GKTIHKFVHQ FPKLELSTHI QPITRGTLRV
1210 1220 1230 1240 1250
ELTITPDFQW DEKVHGQSEG FWVLIEDVDS ELILHHEFFL LKQKYSQDEH
1260 1270 1280 1290 1300
QLKFFVPVFE PLPPQYFLRI VSDRWIGAET QLPVSFRHLI LPEKNMPPTE
1310 1320 1330 1340 1350
LLDLQPLPIS ALRQPKFESF YSQRFPQFNP IQTQVFNAVY NSDENVFVGA
1360 1370 1380 1390 1400
PTGSGKMTIA EFAIMRLFTT QSDARCVYLV SEEALADLVF ADWHSKFGSL
1410 1420 1430 1440 1450
DIKVVKLTGE TGTDLKLIAK GQLVITTADK WDVLSRRWKQ RKNVQLVNLF
1460 1470 1480 1490 1500
IVDELQLVGG EEGPVLEIVC SRMRYISSQI EKQIRIVALS ASLTDARDVA
1510 1520 1530 1540 1550
QWLGCNPNAT FNFHPSVRPI PLELHIQGYN VTHNATRIAT MSKPVYNAIL
1560 1570 1580 1590 1600
KYSAHKPVIV FVSSRKQARL TAIDVLTYAA SDLQPNRFFH AEEEDIKPFL
1610 1620 1630 1640 1650
ERMTDKTLKE TLAQGVAYLH EGLSASDHRL VEQLFDSGAV QVAVISRDLC
1660 1670 1680 1690 1700
WGMSISAHLV IIMDTQFYNG KNHSYEDYPI TDVLQMIGRA NRPNEDADAK
1710 1720 1730 1740 1750
CVLMCQSSKK DFFKKFINEP LPIESHLDHR MHDHFNAEVV TKTIENKQDA
1760 1770 1780 1790 1800
VDYLTWTFLY RRLTQNPNYY NLQGVTHRHL SDHLSELVEN TLSDLEQSKC
1810 1820 1830 1840 1850
ISVEDDMDTL PLNLGMIAAY YYINYTTIEL FSLSLNSKTK VRGLLEIISS
1860 1870 1880 1890 1900
AAEYEDVVVR HHEEQVLRTL SQRLPNKLTG PNETAPKFND PHIKTNLLLQ
1910 1920 1930 1940 1950
AHLSRLQLGP ELQGDTEQIL SKAIRLIQAC VDVLSSNGWL SPAVAAMELA
1960 1970 1980 1990 2000
QMVTQAMWSK DSYLKQLPHF SPEIVKRCTE KKIETVFDIM ELEDEDRTRL
2010 2020 2030 2040 2050
LQLSDLQMAD VARFCNRYPN IELNYEVVDK DRINSGSTVN VVVQLEREDE
2060 2070 2080 2090 2100
VTGPVIAPFF PQKREEGWWV VIGDPKTNSL LSIKRLTLQQ KAKVKLDFVA
2110 2120 2130 2140
PSPGKHDYTL YYMSDSYLGC DQEYKFSIEV GDFQSESESE SD
Length:2,142
Mass (Da):244,510
Last modified:March 1, 2003 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i10CFE9E84438F2BE
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAL39415 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49564.4
BT016121 mRNA Translation: AAV37006.1
AY069270 mRNA Translation: AAL39415.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_648818.3, NM_140561.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0075527; FBpp0075282; FBgn0263599

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
39737

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5931

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49564.4
BT016121 mRNA Translation: AAV37006.1
AY069270 mRNA Translation: AAL39415.1 Different initiation.
RefSeqiNP_648818.3, NM_140561.4

3D structure databases

SMRiQ9VUV9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi65049, 18 interactors
IntActiQ9VUV9, 7 interactors
MINTiQ9VUV9
STRINGi7227.FBpp0075282

Proteomic databases

PaxDbiQ9VUV9
PRIDEiQ9VUV9

Genome annotation databases

EnsemblMetazoaiFBtr0075527; FBpp0075282; FBgn0263599
GeneIDi39737
KEGGidme:Dmel_CG5931

Organism-specific databases

FlyBaseiFBgn0263599, l(3)72Ab

Phylogenomic databases

eggNOGiKOG0951, Eukaryota
GeneTreeiENSGT00940000154966
HOGENOMiCLU_000335_2_1_1
InParanoidiQ9VUV9
KOiK12854
OMAiKKMENWW
OrthoDBi154891at2759
PhylomeDBiQ9VUV9

Enzyme and pathway databases

ReactomeiR-DME-72163, mRNA Splicing - Major Pathway
R-DME-72165, mRNA Splicing - Minor Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
39737, 0 hits in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
l(3)72Ab, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
39737

Protein Ontology

More...
PROi
PR:Q9VUV9

Gene expression databases

BgeeiFBgn0263599, Expressed in embryo and 38 other tissues
GenevisibleiQ9VUV9, DM

Family and domain databases

Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR041094, Brr2_helicase_PWI
IPR035892, C2_domain_sf
IPR011545, DEAD/DEAH_box_helicase_dom
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR014756, Ig_E-set
IPR027417, P-loop_NTPase
IPR004179, Sec63-dom
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF00270, DEAD, 2 hits
PF00271, Helicase_C, 1 hit
PF18149, Helicase_PWI, 1 hit
PF02889, Sec63, 2 hits
SMARTiView protein in SMART
SM00487, DEXDc, 2 hits
SM00490, HELICc, 2 hits
SM00973, Sec63, 2 hits
SUPFAMiSSF46785, SSF46785, 2 hits
SSF52540, SSF52540, 4 hits
SSF81296, SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 2 hits
PS51194, HELICASE_CTER, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiU520_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VUV9
Secondary accession number(s): Q5U0X1, Q8T9I9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2003
Last sequence update: March 1, 2003
Last modified: August 12, 2020
This is version 152 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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