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Entry version 162 (16 Oct 2019)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein, isoform B

Gene

Dmel\CG9425

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein, isoform BImported
Submitted name:
Uncharacterized protein, isoform CImported
Submitted name:
Uncharacterized protein, isoform DImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dmel\CG9425Imported
ORF Names:CG9425Imported, Dmel_CG9425Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0036451 CG9425

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q9VUH9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0036451 Expressed in 31 organ(s), highest expression level in second segment of antenna (Drosophila)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9VUH9, 2 interactors

Molecular INTeraction database

More...
MINTi
Q9VUH9

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0075443

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini281 – 303C2H2-typeInterPro annotationAdd BLAST23

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni195 – 242DisorderedSequence analysisAdd BLAST48
Regioni1355 – 1529DisorderedSequence analysisAdd BLAST175
Regioni1546 – 1645DisorderedSequence analysisAdd BLAST100
Regioni1697 – 1754DisorderedSequence analysisAdd BLAST58
Regioni1792 – 1872DisorderedSequence analysisAdd BLAST81
Regioni2044 – 2068DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi197 – 242PolarSequence analysisAdd BLAST46
Compositional biasi1394 – 1415Pro-richSequence analysisAdd BLAST22
Compositional biasi1439 – 1458PolarSequence analysisAdd BLAST20
Compositional biasi1459 – 1524Pro-richSequence analysisAdd BLAST66
Compositional biasi1557 – 1573Pro-richSequence analysisAdd BLAST17
Compositional biasi1574 – 1590PolarSequence analysisAdd BLAST17
Compositional biasi1591 – 1633Pro-richSequence analysisAdd BLAST43
Compositional biasi1731 – 1754PolarSequence analysisAdd BLAST24
Compositional biasi1803 – 1841PolarSequence analysisAdd BLAST39

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1804 Eukaryota
COG1112 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156686

Identification of Orthologs from Complete Genome Data

More...
OMAi
AWGKLND

Database of Orthologous Groups

More...
OrthoDBi
286011at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041679 DNA2/NAM7-like_AAA
IPR041677 DNA2/NAM7_AAA_11
IPR027417 P-loop_NTPase
IPR011990 TPR-like_helical_dom_sf
IPR013087 Znf_C2H2_type
IPR000571 Znf_CCCH

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13086 AAA_11, 2 hits
PF13087 AAA_12, 1 hit
PF00642 zf-CCCH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 1 hit
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9VUH9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAEKEMQAH DMVRRRSWAR AVALYDQLIA PSPGQGSGGQ SAGSRAQKDQ
60 70 80 90 100
QIACLLGRCE CLLELGKFEG CLADAYKVLT LLSEQTECLA SVSRARRWLV
110 120 130 140 150
HALFKMHKYG DAEIFLSKWI NELSGQQIYS DISKTLERYK SIIQMIMNGQ
160 170 180 190 200
HKAQALKIPH ARLEDEMAIL DTKLDHWATN NLPLDKYSKL LSNKGLKKRE
210 220 230 240 250
QQQQQQQQQQ QQNGNGIGSY ASSSSSSSTG SSSTMSSSST SLHKTNDLLA
260 270 280 290 300
AMKLTAGKHQ PGSGDGSGSD QGDQAAPSTT CSYCTITFQT RNELRQHCQT
310 320 330 340 350
EAHQKVIMSD EGRDWKWRPP PRGYTLDTYS LCETFSEAHI CHYGAQCVEA
360 370 380 390 400
HGQDELNEWK ERFEYRRMRM QKACEKELYG KSYTEQVLDR WIQATAPERV
410 420 430 440 450
MCERVPDMEA RCEQQLVTSI SSKTSKREWL FQLETKKPLK AVALLQDAHR
460 470 480 490 500
NHFALKSIKM CKPTESSMEL KSDQEWLAGS SSQSETSNED SATLIHEITV
510 520 530 540 550
EFHTEIYGTF RQAICFDVGQ EPLLVRHLCV DVLPVNDAEK IEEIKRDIIN
560 570 580 590 600
SSATRWDVAN TQLTRFETTI GTHLKTEAYL SDLEHERELL ERYPCPRAAT
610 620 630 640 650
FTLTQSTIVE KRLTQNNYRS RIHELLSVEE IARYEQIARY NVRTRLTVAS
660 670 680 690 700
NYILTPAGMA TSTAKYSLAG ELFALMRLGK DISEDTSPGR LILSNCSSVY
710 720 730 740 750
ISKPEDPDSK ADPTKRAVYE ALIEDKGKNV IYLKLSAKCV EAMALQADTE
760 770 780 790 800
LEVDIQFQLN RMPYCEWHNA VDKITDFRLI FPATELEPSI PWTPKKQWAD
810 820 830 840 850
SCEPKLNAKQ REAVNAITTA LSIKLPPILL IGPFGTGKTY TLAQAIKQLL
860 870 880 890 900
TQPEAKILIC THSNSAADLY IKEYLHPWIE EGLKEATPLR VYYHKRWSAT
910 920 930 940 950
VNGVVQKYCI TDGVGNFLRP TVEDIMRHRI VVVTLSISME LATLGLPKGL
960 970 980 990 1000
FTHIFLDEAA QAMECEAIMP LALANDSTRI VLAGDHMQMS PELFSAFAKE
1010 1020 1030 1040 1050
RKLHISLLER LYDHYPSNFP CKILLCENYR AHEAIIRFTS ELFYEQKLVA
1060 1070 1080 1090 1100
SGKQPRHDRF YPLTFFTTRG EDVQDKNSTA FYNNAEVYEV VERVSELRKR
1110 1120 1130 1140 1150
WPSAWGKLND TSIGIMTPYS DQVFRIRSEL RKRRMGGISV ERVLNVQGKQ
1160 1170 1180 1190 1200
FRAVFLSTVR TRRTCMPQGS APGSASTTSI GDADADYGFL SNSKLLNTAI
1210 1220 1230 1240 1250
TRAQSLVAVV GDPVALCSIG RCRKVWERFI EICDEHKSLF GLTWSNLRSQ
1260 1270 1280 1290 1300
LDGVELKRGY VLNPLAPEFV PRALQPEAYL REQAALYLNG PQHGHGGHGP
1310 1320 1330 1340 1350
PGPPAHFANA AGMLGPGPAA AAHQMNQMAA AMAANQQQLT AHMYSTHMAM
1360 1370 1380 1390 1400
MAAAVGGKSG NGPGPGTGGG PGPGPGPPPH YGGGGGGGGH MGMRGPPPPA
1410 1420 1430 1440 1450
PHLRGMPPGG PPPTQQPGGA GGGGGPPPPY GQYPAMQHWR PPQQGQNQGP
1460 1470 1480 1490 1500
GQQPPQNPNA SLWGPPPQTN PWSVLPPSKQ PQQPQPPPVS APGRGPGPLP
1510 1520 1530 1540 1550
PPLNANPSLP LRGGSVPPPP PNASTAAHLL RNPSELGYLA KKSLYNHGQA
1560 1570 1580 1590 1600
LPHHQLYGPG PGPPPPPSQQ QPQAPPMGMQ RGSSVPNGPM SPMENGPPPP
1610 1620 1630 1640 1650
PYLRHNGSGY NPGAPPPPPQ QQPQPPPNPF MYAGKQPSPS SMRFGPMTHE
1660 1670 1680 1690 1700
LLPPNVSIYD MAFNPKDEQY KWYVKLLETV GQDGANKFAE MLRQVMATMQ
1710 1720 1730 1740 1750
QQQQQHKPPQ PPMANNPMLN NPHVQRPQYP MMYPQGQQQQ QQQPPQQSVD
1760 1770 1780 1790 1800
ASPPLENFNQ QIDLVFNSIM NGANDVAQPI LRDVLGMVAG TGNAPGPPLS
1810 1820 1830 1840 1850
NGLNGVDLQQ QQQQQQQQQQ SRLFAMMQQQ QQQQQQQQAK PPLGPGPLYP
1860 1870 1880 1890 1900
NHLGGPGLHQ APPNGGGNLS GVGNTNFMGN AGNALLNDKP YNNVGMHNNV
1910 1920 1930 1940 1950
GLNIGGAGVA GHNSNNNNGM LTNGNNSVPL YRRQAHTGNG IGGGNGDYNN
1960 1970 1980 1990 2000
MHGMDAGANL IEALFQANNS VVDHSVKSSD HMHGLLYNNF NGLKGGGHEL
2010 2020 2030 2040 2050
DLFQAMAPSV PHSEAANHHQ QSSGSSATTY AAVLSQGPQA VVGGGVGTGP
2060 2070 2080 2090 2100
SPGQSQAQAG VAGSGTGGKV APAVGRNDLL EKDPFAAIRE LGQATTGFYN

YFQ
Length:2,103
Mass (Da):230,290
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2AE8E4C9B645F1C9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49702.2
AE014296 Genomic DNA Translation: AAS65008.1
AE014296 Genomic DNA Translation: AGB94541.1

NCBI Reference Sequences

More...
RefSeqi
NP_001261848.1, NM_001274919.2
NP_648725.2, NM_140468.3
NP_996084.1, NM_206362.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0075693; FBpp0075443; FBgn0036451
FBtr0333074; FBpp0305287; FBgn0036451
FBtr0333075; FBpp0305288; FBgn0036451

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
39613

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG9425

UCSC genome browser

More...
UCSCi
CG9425-RA d. melanogaster
CG9425-RB d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA Translation: AAF49702.2
AE014296 Genomic DNA Translation: AAS65008.1
AE014296 Genomic DNA Translation: AGB94541.1
RefSeqiNP_001261848.1, NM_001274919.2
NP_648725.2, NM_140468.3
NP_996084.1, NM_206362.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ9VUH9, 2 interactors
MINTiQ9VUH9
STRINGi7227.FBpp0075443

Proteomic databases

PRIDEiQ9VUH9

Genome annotation databases

EnsemblMetazoaiFBtr0075693; FBpp0075443; FBgn0036451
FBtr0333074; FBpp0305287; FBgn0036451
FBtr0333075; FBpp0305288; FBgn0036451
GeneIDi39613
KEGGidme:Dmel_CG9425
UCSCiCG9425-RA d. melanogaster
CG9425-RB d. melanogaster

Organism-specific databases

FlyBaseiFBgn0036451 CG9425

Phylogenomic databases

eggNOGiKOG1804 Eukaryota
COG1112 LUCA
GeneTreeiENSGT00940000156686
OMAiAWGKLND
OrthoDBi286011at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CG9425 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
39613

Gene expression databases

BgeeiFBgn0036451 Expressed in 31 organ(s), highest expression level in second segment of antenna (Drosophila)

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR041679 DNA2/NAM7-like_AAA
IPR041677 DNA2/NAM7_AAA_11
IPR027417 P-loop_NTPase
IPR011990 TPR-like_helical_dom_sf
IPR013087 Znf_C2H2_type
IPR000571 Znf_CCCH
PfamiView protein in Pfam
PF13086 AAA_11, 2 hits
PF13087 AAA_12, 1 hit
PF00642 zf-CCCH, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ9VUH9_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VUH9
Secondary accession number(s): Q7KUL0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: June 26, 2013
Last modified: October 16, 2019
This is version 162 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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