UniProtKB - Q9VT21 (Q9VT21_DROME)
Protein
Submitted name:
GH06403p
Gene
Dmel\CG8336
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- cyclosporin A binding Source: GO_Central
- peptidyl-prolyl cis-trans isomerase activity Source: GO_Central
GO - Biological processi
- protein folding Source: GO_Central
- protein peptidyl-prolyl isomerization Source: GO_Central
Keywordsi
Molecular function | IsomeraseImported |
Enzyme and pathway databases
Reactomei | R-DME-210991, Basigin interactions R-DME-6798695, Neutrophil degranulation |
Names & Taxonomyi
Protein namesi | Submitted name: GH06403pImportedSubmitted name: Uncharacterized protein, isoform AImportedSubmitted name: Uncharacterized protein, isoform BImportedSubmitted name: Uncharacterized protein, isoform CImportedSubmitted name: Uncharacterized protein, isoform DImported (EC:5.2.1.8Imported) |
Gene namesi | Name:Dmel\CG8336Imported ORF Names:CG8336Imported, Dmel_CG8336Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0036020, CG8336 |
Subcellular locationi
Other locations
- cytoplasm Source: GO_Central
- intracellular membrane-bounded organelle Source: GO_Central
Expressioni
Gene expression databases
Bgeei | FBgn0036020, Expressed in imaginal disc and 39 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 18 – 182 | PPIase cyclophilin-typeInterPro annotationAdd BLAST | 165 | |
Domaini | 286 – 353 | TPR_REGIONInterPro annotationAdd BLAST | 68 | |
Repeati | 286 – 319 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 320 – 353 | TPRPROSITE-ProRule annotationAdd BLAST | 34 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 326 – 346 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 353 – 380 | Sequence analysisAdd BLAST | 28 |
Keywords - Domaini
Coiled coilSequence analysis, RepeatARBA annotation, TPR repeatPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG0546, Eukaryota |
GeneTreei | ENSGT00940000173731 |
HOGENOMi | CLU_012062_37_3_1 |
OMAi | CKDFGNK |
OrthoDBi | 1403619at2759 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit 2.40.100.10, 1 hit |
InterProi | View protein in InterPro IPR029000, Cyclophilin-like_dom_sf IPR002130, Cyclophilin-type_PPIase_dom IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat |
Pfami | View protein in Pfam PF00160, Pro_isomerase, 1 hit PF13181, TPR_8, 1 hit |
PRINTSi | PR00153, CSAPPISMRASE |
SMARTi | View protein in SMART SM00028, TPR, 2 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit SSF50891, SSF50891, 1 hit |
PROSITEi | View protein in PROSITE PS50072, CSA_PPIASE_2, 1 hit PS50005, TPR, 2 hits PS50293, TPR_REGION, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9VT21-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEERKLLRAV KSTNPLVYLD ISIGKEDAGR MIIELRKDVV PKTAENFRAL
60 70 80 90 100
CTGECGIGTL GKPLHYKGTK FHKIKRVFVV QSGDVVKNDG SSGESIYGPV
110 120 130 140 150
FDDENFELSH NEEGVVSMAN YGKPNSNNSQ FFISAAGCEN LNGTNVVVGR
160 170 180 190 200
VLRGLGIVAE MEQNCTDEGD PTAPIVIRDC GEIAHNEDWG IECNDETTDK
210 220 230 240 250
LPAYPQDWPR KLDKFTGDGA VELLTGIRQS GNHFYQLGRY HEARAKYRKA
260 270 280 290 300
NRYYHYLSRQ FGWQQLNPLK KHLVDEDLLK VDGFSVVNNI NAAAVDLKVG
310 320 330 340 350
NYTSAREVCN EAIRLDPKCS KAFYRRAQAQ RGLRNYEEAI NDLKTAHNLL
360 370 380
PENKQILNEL NSTKQLLAQY NRQQRNALKN LFA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF50235.1 AY058303 mRNA Translation: AAL13532.1 AE014296 Genomic DNA Translation: AAN11947.1 AE014296 Genomic DNA Translation: AAN11948.1 AE014296 Genomic DNA Translation: AGB94331.1 |
RefSeqi | NP_001261636.1, NM_001274707.1 NP_648338.1, NM_140081.3 NP_729517.1, NM_168354.2 NP_729518.1, NM_168355.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0076384; FBpp0076113; FBgn0036020 FBtr0076385; FBpp0076114; FBgn0036020 FBtr0076386; FBpp0076115; FBgn0036020 FBtr0333855; FBpp0305988; FBgn0036020 |
GeneIDi | 39121 |
KEGGi | dme:Dmel_CG8336 |
UCSCi | CG8336-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014296 Genomic DNA Translation: AAF50235.1 AY058303 mRNA Translation: AAL13532.1 AE014296 Genomic DNA Translation: AAN11947.1 AE014296 Genomic DNA Translation: AAN11948.1 AE014296 Genomic DNA Translation: AGB94331.1 |
RefSeqi | NP_001261636.1, NM_001274707.1 NP_648338.1, NM_140081.3 NP_729517.1, NM_168354.2 NP_729518.1, NM_168355.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7227.FBpp0076113 |
Genome annotation databases
EnsemblMetazoai | FBtr0076384; FBpp0076113; FBgn0036020 FBtr0076385; FBpp0076114; FBgn0036020 FBtr0076386; FBpp0076115; FBgn0036020 FBtr0333855; FBpp0305988; FBgn0036020 |
GeneIDi | 39121 |
KEGGi | dme:Dmel_CG8336 |
UCSCi | CG8336-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0036020, CG8336 |
Phylogenomic databases
eggNOGi | KOG0546, Eukaryota |
GeneTreei | ENSGT00940000173731 |
HOGENOMi | CLU_012062_37_3_1 |
OMAi | CKDFGNK |
OrthoDBi | 1403619at2759 |
Enzyme and pathway databases
Reactomei | R-DME-210991, Basigin interactions R-DME-6798695, Neutrophil degranulation |
Miscellaneous databases
BioGRID-ORCSi | 39121, 0 hits in 1 CRISPR screen |
GenomeRNAii | 39121 |
Gene expression databases
Bgeei | FBgn0036020, Expressed in imaginal disc and 39 other tissues |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit 2.40.100.10, 1 hit |
InterProi | View protein in InterPro IPR029000, Cyclophilin-like_dom_sf IPR002130, Cyclophilin-type_PPIase_dom IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat |
Pfami | View protein in Pfam PF00160, Pro_isomerase, 1 hit PF13181, TPR_8, 1 hit |
PRINTSi | PR00153, CSAPPISMRASE |
SMARTi | View protein in SMART SM00028, TPR, 2 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit SSF50891, SSF50891, 1 hit |
PROSITEi | View protein in PROSITE PS50072, CSA_PPIASE_2, 1 hit PS50005, TPR, 2 hits PS50293, TPR_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9VT21_DROME | |
Accessioni | Q9VT21Primary (citable) accession number: Q9VT21 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | February 10, 2021 | |
This is version 183 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |